Notch signaling suppresses glucose metabolism in mesenchymal progenitors to restrict osteoblast differentiation
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Title
Notch signaling suppresses glucose metabolism in mesenchymal progenitors to restrict osteoblast differentiation
Authors
Keywords
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Journal
JOURNAL OF CLINICAL INVESTIGATION
Volume 128, Issue 12, Pages 5573-5586
Publisher
American Society for Clinical Investigation
Online
2018-10-05
DOI
10.1172/jci96221
References
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Note: Only part of the references are listed.- Energy Metabolism of the Osteoblast: Implications for Osteoporosis
- (2017) Wen-Chih Lee et al. ENDOCRINE REVIEWS
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- (2017) Rialnat A Lawal et al. JOURNAL OF BONE AND MINERAL RESEARCH
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- (2016) Timur Yorgan et al. BONE
- Notch stimulates growth by direct regulation of genes involved in the control of glycolysis and the tricarboxylic acid cycle
- (2016) Vera Slaninova et al. Open Biology
- Glucose Uptake and Runx2 Synergize to Orchestrate Osteoblast Differentiation and Bone Formation
- (2015) Jianwen Wei et al. CELL
- Hajdu Cheney Mouse Mutants Exhibit Osteopenia, Increased Osteoclastogenesis, and Bone Resorption
- (2015) Ernesto Canalis et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PTH Promotes Bone Anabolism by Stimulating Aerobic Glycolysis via IGF Signaling
- (2015) Emel Esen et al. JOURNAL OF BONE AND MINERAL RESEARCH
- NOTCH reprograms mitochondrial metabolism for proinflammatory macrophage activation
- (2015) Jun Xu et al. JOURNAL OF CLINICAL INVESTIGATION
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- (2015) Julie L. Frey et al. MOLECULAR AND CELLULAR BIOLOGY
- MnSOD upregulation sustains the Warburg effect via mitochondrial ROS and AMPK-dependent signalling in cancer
- (2015) Peter C. Hart et al. Nature Communications
- Alteration of Mitochondrial Proteome Due to Activation of Notch1 Signaling Pathway
- (2014) Nandini Pal Basak et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- NOTCH inhibits osteoblast formation in inflammatory arthritis via noncanonical NF-κB
- (2014) Hengwei Zhang et al. JOURNAL OF CLINICAL INVESTIGATION
- Increased glutamine catabolism mediates bone anabolism in response to WNT signaling
- (2014) Courtney M. Karner et al. JOURNAL OF CLINICAL INVESTIGATION
- Role of PFKFB3-Driven Glycolysis in Vessel Sprouting
- (2013) Katrien De Bock et al. CELL
- WNT-LRP5 Signaling Induces Warburg Effect through mTORC2 Activation during Osteoblast Differentiation
- (2013) Emel Esen et al. Cell Metabolism
- Treatment Trends and Outcomes of Small-Cell Carcinoma of the Bladder: In Regard to Koay et al. (Int J Radiat Oncol Biol Phys 2011 Oct 20)
- (2012) Nabil Ismaili INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Physiological Notch Signaling Maintains Bone Homeostasis via RBPjk and Hey Upstream of NFATc1
- (2012) Xiaolin Tu et al. PLoS Genetics
- Truncating mutations in the last exon of NOTCH2 cause a rare skeletal disorder with osteoporosis
- (2011) Bertrand Isidor et al. NATURE GENETICS
- Mutations in NOTCH2 cause Hajdu-Cheney syndrome, a disorder of severe and progressive bone loss
- (2011) Michael A Simpson et al. NATURE GENETICS
- Hypo- and hyperactivated Notch signaling induce a glycolytic switch through distinct mechanisms
- (2011) S. K.- J. Landor et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Notch2 Activation in the Embryonic Kidney Depletes Nephron Progenitors
- (2010) S. Fujimura et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism
- (2009) Raphael Kopan et al. CELL
- Notch Inhibits Osteoblast Differentiation and Causes Osteopenia
- (2008) Stefano Zanotti et al. ENDOCRINOLOGY
- Small-molecule inhibition of 6-phosphofructo-2-kinase activity suppresses glycolytic flux and tumor growth
- (2008) B. Clem et al. MOLECULAR CANCER THERAPEUTICS
- Dimorphic effects of Notch signaling in bone homeostasis
- (2008) Feyza Engin et al. NATURE MEDICINE
- Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation
- (2008) Matthew J Hilton et al. NATURE MEDICINE
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