Myeloid‐derived suppressor cells and tumor: Current knowledge and future perspectives

The role of STAT3 in leading the crosstalk between human cancers and the immune system

(2018) Yu Wang et al.   CANCER LETTERS

Presence of S100A8/Gr1-Positive Myeloid-Derived Suppressor Cells in Primary Tumors and Visceral Organs Invaded by Breast Carcinoma Cells

(2018) Gamze Tanriover et al.   Clinical Breast Cancer

Plasticity of myeloid-derived suppressor cells in cancer

(2018) Evgenii Tcyganov et al.   CURRENT OPINION IN IMMUNOLOGY

Activation of p53 in Immature Myeloid Precursor Cells Controls Differentiation into Ly6c + CD103 + Monocytic Antigen-Presenting Cells in Tumors

(2018) Madhav D. Sharma et al.   IMMUNITY

Phytochemicals inhibit the immunosuppressive functions of myeloid-derived suppressor cells (MDSC): Impact on cancer and age-related chronic inflammatory disorders

(2018) Antero Salminen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The host protecting the tumor from the host — targeting PD‑L1 expressed by host cells

(2018) David H. Munn   JOURNAL OF CLINICAL INVESTIGATION

Myeloid-Derived Suppressor Cells: Immune-Suppressive Cells That Impair Antitumor Immunity and Are Sculpted by Their Environment

(2018) Suzanne Ostrand-Rosenberg et al.   JOURNAL OF IMMUNOLOGY

Abstract 3447: IL-6 promotes tumor metastasis by promoting anoikis resistance and stemness phenotype in cancer cells via the activation of FAK and nanog stabilization

(2018) Arti Yadav et al.   CANCER RESEARCH

SOCS3 Suppression Promoted the Recruitment of CD11b+Gr-1−F4/80−MHCII− Early-Stage Myeloid-Derived Suppressor Cells and Accelerated Interleukin-6-Related Tumor Invasion via Affecting Myeloid Differentiation in Breast Cancer

(2018) Wenwen Zhang et al.   Frontiers in Immunology

Neutrophils, G-CSF and their contribution to breast cancer metastasis

(2017) Kellie A. Mouchemore et al.   FEBS Journal

Recruited monocytic myeloid-derived suppressor cells promote the arrest of tumor cells in the premetastatic niche through an IL-1β-mediated increase in E-selectin expression

(2017) Huifang Shi et al.   INTERNATIONAL JOURNAL OF CANCER

The Dark Side of IFN-γ: Its Role in Promoting Cancer Immunoevasion

(2017) Marija Mojic et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Myeloid-derived suppressor cells: Important contributors to tumor progression and metastasis

(2017) Elham Safarzadeh et al.   JOURNAL OF CELLULAR PHYSIOLOGY

DNA-Containing Exosomes Derived from Cancer Cells Treated with Topotecan Activate a STING-Dependent Pathway and Reinforce Antitumor Immunity

(2017) Yuichi Kitai et al.   JOURNAL OF IMMUNOLOGY

Novel Role of S100A9-Induced Overexpression of PD-1/PD-L1 in HSPC and MDSC Contribute to Ineffective Hematopoiesis in MDS

(2017) S. Wei et al.   LEUKEMIA RESEARCH

Role of exosomal proteins in cancer diagnosis

(2017) Weihua Li et al.   Molecular Cancer

STING, DCs and the link between innate and adaptive tumor immunity

(2017) Ralph E. Vatner et al.   MOLECULAR IMMUNOLOGY

Chemerin has a protective role in hepatocellular carcinoma by inhibiting the expression of IL-6 and GM-CSF and MDSC accumulation

(2017) Y Lin et al.   ONCOGENE

Tumour-derived PGD2 and NKp30-B7H6 engagement drives an immunosuppressive ILC2-MDSC axis

(2017) Sara Trabanelli et al.   Nature Communications

T-cell defect in diffuse large B-cell lymphomas involves expansion of myeloid-derived suppressor cells

(2016) I. Azzaoui et al.   BLOOD

Toward harmonized phenotyping of human myeloid-derived suppressor cells by flow cytometry: results from an interim study

(2016) Susanna Mandruzzato et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

IL6 Blockade Reprograms the Lung Tumor Microenvironment to Limit the Development and Progression of K-ras-Mutant Lung Cancer

(2016) M. S. Caetano et al.   CANCER RESEARCH

Abstract 4155: Regulation of MDSC trafficking and function in RCC by CXCR4 in the presence of a VEGF-R antagonist

(2016) David J. Panka et al.   CANCER RESEARCH

Human Head and Neck Squamous Cell Carcinoma–Associated Semaphorin 4D Induces Expansion of Myeloid-Derived Suppressor Cells

(2016) Rania H. Younis et al.   JOURNAL OF IMMUNOLOGY

The Nature of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment

(2016) Vinit Kumar et al.   TRENDS IN IMMUNOLOGY

Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards

(2016) Vincenzo Bronte et al.   Nature Communications

Granulocytic myeloid-derived suppressor cells promote angiogenesis in the context of multiple myeloma

(2016) Marilène Binsfeld et al.   Oncotarget

Regulation of Tumor Metastasis by Myeloid-Derived Suppressor Cells

(2015) Thomas Condamine et al.   Annual Review of Medicine

RORC1 Regulates Tumor-Promoting “Emergency” Granulo-Monocytopoiesis

(2015) Laura Strauss et al.   CANCER CELL

Sunitinib pretreatment improves tumor-infiltrating lymphocyte expansion by reduction in intratumoral content of myeloid-derived suppressor cells in human renal cell carcinoma

(2015) Aurelie Guislain et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Abstract B03: Hypoxia-induced carbonic anhydrase IX promotes MDSC recruitment and establishment of the breast cancer premetastatic niche by stimulating G-CSF production

(2015) Shawn C. Chafe et al.   CANCER RESEARCH

Targeting of IL-4 and IL-13 receptors for cancer therapy

(2015) Akiko Suzuki et al.   CYTOKINE

Myeloid-derived suppressor cells in the tumor microenvironment: expect the unexpected

(2015) Douglas Marvel et al.   JOURNAL OF CLINICAL INVESTIGATION

Tumor-induced myeloid deviation: when myeloid-derived suppressor cells meet tumor-associated macrophages

(2015) Stefano Ugel et al.   JOURNAL OF CLINICAL INVESTIGATION

Tumor-induced myeloid-derived suppressor cells promote tumor progression through oxidative metabolism in human colorectal cancer

(2015) Li-Ying OuYang et al.   Journal of Translational Medicine

Exosomal Hsp70 mediates immunosuppressive activity of the myeloid-derived suppressor cells via phosphorylation of Stat3

(2015) Jianjun Diao et al.   MEDICAL ONCOLOGY

The immunobiology of myeloid-derived suppressor cells in cancer

(2015) Morteza Motallebnezhad et al.   TUMOR BIOLOGY

MPGES-1-derived PGE2 suppresses CD80 expression on tumor-associated phagocytes to inhibit anti-tumor immune responses in breast cancer

(2015) Catherine Olesch et al.   Oncotarget

Regulation of the inflammatory profile of stromal cells in human breast cancer: prominent roles for TNF-α and the NF-κB pathway

(2015) Christina Katanov et al.   Stem Cell Research & Therapy

CCL2 Promotes Colorectal Carcinogenesis by Enhancing Polymorphonuclear Myeloid-Derived Suppressor Cell Population and Function

(2015) Eunyoung Chun et al.   Cell Reports

Paving the Road to Tumor Development and Spreading: Myeloid-Derived Suppressor Cells are Ruling the Fate

(2015) Yaron Meirow et al.   Frontiers in Immunology

Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment

(2015) Kirsten Ridder et al.   OncoImmunology

Myeloid-derived suppressor cell heterogeneity in human cancers

(2014) Samantha Solito et al.   Annals of the New York Academy of Sciences

Human fibrocytic myeloid-derived suppressor cells express IDO and promote tolerance via Treg-cell expansion

(2014) Alessia Zoso et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Myeloid-derived suppressor cells in malignant melanoma

(2014) Viktor Umansky et al.   JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT

PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activation

(2014) Muhammad Zaeem Noman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Proinflammatory S100 Proteins Regulate the Accumulation of Myeloid-Derived Suppressor Cells

(2014) P. Sinha et al.   JOURNAL OF IMMUNOLOGY

Subsets of Myeloid-Derived Suppressor Cells in Tumor-Bearing Mice

(2014) J.-I. Youn et al.   JOURNAL OF IMMUNOLOGY

Galectin-3 contributes to cisplatin-induced myeloid derived suppressor cells (MDSCs) recruitment in Lewis lung cancer-bearing mice

(2014) Tian Wang et al.   MOLECULAR BIOLOGY REPORTS

Generation of a new therapeutic peptide that depletes myeloid-derived suppressor cells in tumor-bearing mice

(2014) Hong Qin et al.   NATURE MEDICINE

Infiltration of Alternatively Activated Macrophages in Cancer Tissue Is Associated with MDSC and Th2 Polarization in Patients with Esophageal Cancer

(2014) Jingjing Gao et al.   PLoS One

Myeloid-Derived Suppressor Cells in Cancer: Therapeutic, Predictive, and Prognostic Implications

(2014) C. Marcela Diaz-Montero et al.   SEMINARS IN ONCOLOGY

Fibrocytes represent a novel MDSC subset circulating in patients with metastatic cancer

(2013) H. Zhang et al.   BLOOD

CXCR2-Expressing Myeloid-Derived Suppressor Cells Are Essential to Promote Colitis-Associated Tumorigenesis

(2013) Hiroshi Katoh et al.   CANCER CELL

The effects of gemcitabine and capecitabine combination chemotherapy and of low-dose adjuvant GM-CSF on the levels of myeloid-derived suppressor cells in patients with advanced pancreatic cancer

(2013) Nicola E. Annels et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Increased CD14+HLA-DR-/low myeloid-derived suppressor cells correlate with extrathoracic metastasis and poor response to chemotherapy in non-small cell lung cancer patients

(2013) Ang Huang et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Cancer immunotherapy strategies based on overcoming barriers within the tumor microenvironment

(2013) Thomas F Gajewski et al.   CURRENT OPINION IN IMMUNOLOGY

Tumor Necrosis Factor-α Blocks Differentiation and Enhances Suppressive Activity of Immature Myeloid Cells during Chronic Inflammation

(2013) Moshe Sade-Feldman et al.   IMMUNITY

Vemurafenib reverses immunosuppression by myeloid derived suppressor cells

(2013) Bastian Schilling et al.   INTERNATIONAL JOURNAL OF CANCER

Myeloid-derived suppressor cell development is regulated by a STAT/IRF-8 axis

(2013) Jeremy D. Waight et al.   JOURNAL OF CLINICAL INVESTIGATION

Transmembrane TNF-  Promotes Suppressive Activities of Myeloid-Derived Suppressor Cells via TNFR2

(2013) X. Hu et al.   JOURNAL OF IMMUNOLOGY

Reciprocal Relationship between Myeloid-Derived Suppressor Cells and T Cells

(2013) S. Nagaraj et al.   JOURNAL OF IMMUNOLOGY

Up-Regulation of PD-L1, IDO, and Tregs in the Melanoma Tumor Microenvironment Is Driven by CD8+ T Cells

(2013) S. Spranger et al.   Science Translational Medicine

Myeloid-Derived Suppressor Cells Interact with Tumors in Terms of Myelopoiesis, Tumorigenesis and Immunosuppression: Thick as Thieves

(2013) Alexandra Sevko et al.   Journal of Cancer

Multipotent Human Mesenchymal Stromal Cells Mediate Expansion of Myeloid-Derived Suppressor Cells via Hepatocyte Growth Factor/c-Met and STAT3

(2013) B. Linju Yen et al.   Stem Cell Reports

The metastatic niche and stromal progression

(2012) Jonathan P. Sleeman   CANCER AND METASTASIS REVIEWS

Tumor-Derived Granulocyte-Macrophage Colony-Stimulating Factor Regulates Myeloid Inflammation and T Cell Immunity in Pancreatic Cancer

(2012) Lauren J. Bayne et al.   CANCER CELL

Pancreatic adenocarcinoma induces bone marrow mobilization of myeloid-derived suppressor cells which promote primary tumor growth

(2012) Matthew R. Porembka et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Neutrophils and granulocytic myeloid-derived suppressor cells: immunophenotyping, cell biology and clinical relevance in human oncology

(2012) Claudia A. Dumitru et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

MUC1 Vaccine for Individuals with Advanced Adenoma of the Colon: A Cancer Immunoprevention Feasibility Study

(2012) T. Kimura et al.   Cancer Prevention Research

Aptamer-Mediated Blockade of IL4R  Triggers Apoptosis of MDSCs and Limits Tumor Progression

(2012) F. Roth et al.   CANCER RESEARCH

Anti-IL-6 receptor mAb eliminates myeloid-derived suppressor cells and inhibits tumor growth by enhancing T-cell responses

(2012) Kentaro Sumida et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mice That Express Human Interleukin-8 Have Increased Mobilization of Immature Myeloid Cells, Which Exacerbates Inflammation and Accelerates Colon Carcinogenesis

(2012) Samuel Asfaha et al.   GASTROENTEROLOGY

Myeloid derived suppressor cells (MDSCs) can induce the generation of Th17 response from naïve CD4+ T cells

(2012) Shilpak Chatterjee et al.   IMMUNOBIOLOGY

Mouse CD11b + Gr-1 + Myeloid Cells Can Promote Th17 Cell Differentiation and Experimental Autoimmune Encephalomyelitis

(2012) Huanfa Yi et al.   JOURNAL OF IMMUNOLOGY

Myeloid-derived Suppressor Cells in Cancer Patients

(2012) Alberto J. Montero et al.   JOURNAL OF IMMUNOTHERAPY

Significance of IL-6 in the transition of hormone-resistant prostate cancer and the induction of myeloid-derived suppressor cells

(2012) Chun-Te Wu et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

New insights into chronic inflammation-induced immunosuppression

(2012) Julia Kanterman et al.   SEMINARS IN CANCER BIOLOGY

Melanoma-induced immunosuppression and its neutralization

(2012) Viktor Umansky et al.   SEMINARS IN CANCER BIOLOGY

Recent advances on the role of tumor exosomes in immunosuppression and disease progression

(2012) Paola Filipazzi et al.   SEMINARS IN CANCER BIOLOGY

Cross-talk between myeloid-derived suppressor cells (MDSC), macrophages, and dendritic cells enhances tumor-induced immune suppression

(2012) Suzanne Ostrand-Rosenberg et al.   SEMINARS IN CANCER BIOLOGY

Role of HLA-G in tumor escape through expansion of myeloid-derived suppressor cells and cytokinic balance in favor of Th2 versus Th1/Th17

(2011) S. Agaugue et al.   BLOOD

Matrix metalloproteinase 12 overexpression in myeloid lineage cells plays a key role in modulating myelopoiesis, immune suppression, and lung tumorigenesis

(2011) P. Qu et al.   BLOOD

Positive feedback between PGE2 and COX2 redirects the differentiation of human dendritic cells toward stable myeloid-derived suppressor cells

(2011) N. Obermajer et al.   BLOOD

A human promyelocytic-like population is responsible for the immune suppression mediated by myeloid-derived suppressor cells

(2011) S. Solito et al.   BLOOD

Angiogenesis and immunity: a bidirectional link potentially relevant for the monitoring of antiangiogenic therapy and the development of novel therapeutic combination with immunotherapy

(2011) Eric Tartour et al.   CANCER AND METASTASIS REVIEWS

Overcoming immunosuppression in the melanoma microenvironment induced by chronic inflammation

(2011) Viktor Umansky et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

COX-2 Blockade Suppresses Gliomagenesis by Inhibiting Myeloid-Derived Suppressor Cells

(2011) M. Fujita et al.   CANCER RESEARCH

The Two Faces of Interferon-  in Cancer

(2011) M. R. Zaidi et al.   CLINICAL CANCER RESEARCH

Granulocyte–macrophage colony-stimulating factor as an autocrine survival-growth factor in human gliomas

(2011) Roberto P. Revoltella et al.   CYTOKINE

Myeloid derived suppressor cells in human diseases

(2011) Tim F. Greten et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Chemokine nitration prevents intratumoral infiltration of antigen-specific T cells

(2011) Barbara Molon et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Crucial Role of Granulocytic Myeloid-Derived Suppressor Cells in the Regulation of Central Nervous System Autoimmune Disease

(2011) M. Ioannou et al.   JOURNAL OF IMMUNOLOGY

Functional characterization of human Cd33+ And Cd11b+ myeloid-derived suppressor cell subsets induced from peripheral blood mononuclear cells co-cultured with a diverse set of human tumor cell lines

(2011) Melissa G Lechner et al.   Journal of Translational Medicine

Tumor-Derived G-CSF Facilitates Neoplastic Growth through a Granulocytic Myeloid-Derived Suppressor Cell-Dependent Mechanism

(2011) Jeremy D. Waight et al.   PLoS One

Chronic inflammation promotes myeloid-derived suppressor cell activation blocking antitumor immunity in transgenic mouse melanoma model

(2011) C. Meyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The secreted factors responsible for pre-metastatic niche formation: Old sayings and new thoughts

(2011) Héctor Peinado et al.   SEMINARS IN CANCER BIOLOGY

CD15+/CD16low human granulocytes from terminal cancer patients: granulocytic myeloid-derived suppressor cells that have suppressive function

(2011) Jahyang Choi et al.   TUMOR BIOLOGY

Leukocyte Complexity Predicts Breast Cancer Survival and Functionally Regulates Response to Chemotherapy

(2011) David G. DeNardo et al.   Cancer Discovery

Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1-dependent mechanism that is up-regulated by interleukin-13

(2010) S. L. Highfill et al.   BLOOD

Zoledronic acid impairs myeloid differentiation to tumour-associated macrophages in mesothelioma

(2010) J D Veltman et al.   BRITISH JOURNAL OF CANCER

Myeloid-derived suppressor cells: more mechanisms for inhibiting antitumor immunity

(2010) Suzanne Ostrand-Rosenberg   CANCER IMMUNOLOGY IMMUNOTHERAPY

Immature Immunosuppressive CD14+HLA-DR−/low Cells in Melanoma Patients Are Stat3hi and Overexpress CD80, CD83, and DC-Sign

(2010) Isabel Poschke et al.   CANCER RESEARCH

5-Fluorouracil Selectively Kills Tumor-Associated Myeloid-Derived Suppressor Cells Resulting in Enhanced T Cell-Dependent Antitumor Immunity

(2010) J. Vincent et al.   CANCER RESEARCH

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

IL-1β regulates a novel myeloid-derived suppressor cell subset that impairs NK cell development and function

(2010) Moshe Elkabets et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Tumor-Induced Tolerance and Immune Suppression Depend on the C/EBPβ Transcription Factor

(2010) Ilaria Marigo et al.   IMMUNITY

Gr-1+CD11b+ myeloid-derived suppressor cells: Formidable partners in tumor metastasis

(2010) Li Yang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

IL-17 Promotes Tumor Development through the Induction of Tumor Promoting Microenvironments at Tumor Sites and Myeloid-Derived Suppressor Cells

(2010) Donggou He et al.   JOURNAL OF IMMUNOLOGY

Changes in Dendritic Cell Phenotype After a New High-dose Weekly Schedule of Interleukin-2 Therapy for Kidney Cancer and Melanoma

(2010) Steven E. Finkelstein et al.   JOURNAL OF IMMUNOTHERAPY

Subsets, expansion and activation of myeloid-derived suppressor cells

(2010) Eliana Ribechini et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes

(2010) M. Kowanetz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stat 6-Dependent Induction of Myeloid Derived Suppressor Cells After Physical Injury Regulates Nitric Oxide Response to Endotoxin

(2009) Veronica Munera et al.   ANNALS OF SURGERY

Complex and Context Dependent Regulation of Hematopoiesis by TGF-β Superfamily Signaling

(2009) Sofie Singbrant Söderberg et al.   Annals of the New York Academy of Sciences

Targeting distinct tumor-infiltrating myeloid cells by inhibiting CSF-1 receptor: combating tumor evasion of antiangiogenic therapy

(2009) S. J. Priceman et al.   BLOOD

GM-CSF is one of the main breast tumor-derived soluble factors involved in the differentiation of CD11b-Gr1- bone marrow progenitor cells into myeloid-derived suppressor cells

(2009) Johanna K. Morales et al.   BREAST CANCER RESEARCH AND TREATMENT

IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer

(2009) Sergei Grivennikov et al.   CANCER CELL

Myeloid-Derived Suppressor Cells Inhibit T-Cell Activation by Depleting Cystine and Cysteine

(2009) M. K. Srivastava et al.   CANCER RESEARCH

CC chemokine ligand 2 (CCL2) promotes prostate cancer tumorigenesis and metastasis

(2009) Jian Zhang et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Hierarchy of immunosuppressive strength among myeloid-derived suppressor cell subsets is determined by GM-CSF

(2009) Luigi Dolcetti et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Myeloid-derived suppressor cells in inflammation: Uncovering cell subsets with enhanced immunosuppressive functions

(2009) Vincenzo Bronte   EUROPEAN JOURNAL OF IMMUNOLOGY

Myeloid derived suppressor cells inhibit natural killer cells in patients with hepatocellular carcinoma via the NKp30 receptor

(2009) Bastian Hoechst et al.   HEPATOLOGY

Mammary tumor heterogeneity in the expansion of myeloid-derived suppressor cells

(2009) Moses K. Donkor et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Mechanism Regulating Reactive Oxygen Species in Tumor-Induced Myeloid-Derived Suppressor Cells

(2009) C. A. Corzo et al.   JOURNAL OF IMMUNOLOGY

Inflammation enhances myeloid-derived suppressor cell cross-talk by signaling through Toll-like receptor 4

(2009) Stephanie K. Bunt et al.   JOURNAL OF LEUKOCYTE BIOLOGY

G-CSF-initiated myeloid cell mobilization and angiogenesis mediate tumor refractoriness to anti-VEGF therapy in mouse models

(2009) F. Shojaei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity

(2008) K. Movahedi et al.   BLOOD

Overexpression of Interleukin-1β Induces Gastric Inflammation and Cancer and Mobilizes Myeloid-Derived Suppressor Cells in Mice

(2008) Shuiping Tu et al.   CANCER CELL

Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein

(2008) Pingyan Cheng et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ IL-10+ Foxp3− effector T cells

(2008) Valérie Dardalhon et al.   NATURE IMMUNOLOGY

Melanoma and innate immunity – Active inflammation or just erroneous attraction?

(2008) Alexander A. Navarini-Meury et al.   SEMINARS IN CANCER BIOLOGY