Heme oxygenase-1 protects airway epithelium against apoptosis by targeting the proinflammatory NLRP3–RXR axis in asthma

Induction of heme oxygenas-1 attenuates NLRP3 inflammasome activation in lipopolysaccharide-induced mastitis in mice

(2017) Hu Xiaoyu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice

(2017) Auvro R. Mridha et al.   JOURNAL OF HEPATOLOGY

TLR9 Regulates the NF-κB–NLRP3–IL-1β Pathway Negatively inSalmonella-Induced NKG2D-Mediated Intestinal Inflammation

(2017) Yan Li et al.   JOURNAL OF IMMUNOLOGY

NLRP3 Inflammasome Mediates Aldosterone-Induced Vascular DamageClinical Perspective

(2016) Thiago Bruder-Nascimento et al.   CIRCULATION

CORM-2 inhibits TXNIP/NLRP3 inflammasome pathway in LPS-induced acute lung injury

(2016) Lei Jiang et al.   INFLAMMATION RESEARCH

p52 Overexpression Increases Epithelial Apoptosis, Enhances Lung Injury, and Reduces Survival after Lipopolysaccharide Treatment

(2016) Jamie A. Saxon et al.   JOURNAL OF IMMUNOLOGY

Excess aldosterone is a critical danger signal for inflammasome activation in the development of renal fibrosis in mice

(2015) Hiroyuki Kadoya et al.   FASEB JOURNAL

The immunology of asthma

(2015) Bart N Lambrecht et al.   NATURE IMMUNOLOGY

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

(2015) Rebecca C Coll et al.   NATURE MEDICINE

Effects of RXR Agonists on Cell Proliferation/Apoptosis and ACTH Secretion/Pomc Expression

(2015) Akiko Saito-Hakoda et al.   PLoS One

Protective role of HO-1 and carbon monoxide in ethanol-induced hepatocyte cell death and liver injury in mice

(2014) Bakytzhan Bakhautdin et al.   JOURNAL OF HEPATOLOGY

Thrombomodulin domain 1 ameliorates diabetic nephropathy in mice via anti-NF-κB/NLRP3 inflammasome-mediated inflammation, enhancement of NRF2 antioxidant activity and inhibition of apoptosis

(2013) Shun-Min Yang et al.   DIABETOLOGIA

Retinoic X receptor subtypes exert differential effects on the regulation of Trh transcription

(2013) Stéphanie Decherf et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Asthma and Coagulation

(2013) Bart N. Lambrecht et al.   NEW ENGLAND JOURNAL OF MEDICINE

A2E Induces IL-1ß Production in Retinal Pigment Epithelial Cells via the NLRP3 Inflammasome

(2013) Owen A. Anderson et al.   PLoS One

NLRP3 inflammasome is required in murine asthma in the absence of aluminum adjuvant

(2011) A.-G. Besnard et al.   ALLERGY

Retinoid pathway and cancer therapeutics

(2010) Nathan Bushue et al.   ADVANCED DRUG DELIVERY REVIEWS

Mechanisms of Cell Protection by Heme Oxygenase-1

(2010) Raffaella Gozzelino et al.   Annual Review of Pharmacology and Toxicology

NF-κB–Inhibited Acute Myeloid Leukemia Cells Are Rescued from Apoptosis by Heme Oxygenase-1 Induction

(2010) Stuart A. Rushworth et al.   CANCER RESEARCH

Pre-activation of retinoid signaling facilitates neuronal differentiation of mesenchymal stem cells

(2010) Yang Bi et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

IL-13 and TH2 cytokine exposure triggers matrix metalloproteinase 7–mediated Fas ligand cleavage from bronchial epithelial cells

(2010) Samuel J. Wadsworth et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Retinoid X receptor   controls innate inflammatory responses through the up-regulation of chemokine expression

(2010) V. Nunez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Growth Factor-Antagonized Rexinoid Apoptosis Involves Permissive PPARγ/RXR Heterodimers to Activate the Intrinsic Death Pathway by NO

(2009) Pattabhiraman Shankaranarayanan et al.   CANCER CELL

HO-1 underlies resistance of AML cells to TNF-induced apoptosis

(2008) S. A. Rushworth et al.   BLOOD

Pharmacological and Clinical Aspects of Heme Oxygenase

(2008) N. G. Abraham et al.   PHARMACOLOGICAL REVIEWS