The Role of Copper Homeostasis at the Host-Pathogen Axis: From Bacteria to Fungi

Genome-wide analysis of the regulation of Cu metabolism in Cryptococcus neoformans

(2018) Sarela Garcia-Santamarina et al.   MOLECULAR MICROBIOLOGY

The CpxR/CpxA system contributes to Salmonella gold-resistance by controlling the GolS-dependent gesABC transcription

(2017) Sebastián Cerminati et al.   ENVIRONMENTAL MICROBIOLOGY

Aspergillus fumigatus morphology and dynamic host interactions

(2017) Frank L. van de Veerdonk et al.   NATURE REVIEWS MICROBIOLOGY

Cryptococcus neoformans Iron-Sulfur Protein Biogenesis Machinery Is a Novel Layer of Protection against Cu Stress

(2017) Sarela Garcia-Santamarina et al.   mBio

Stop neglecting fungi

(2017)   Nature Microbiology

Iron, Copper, and Zinc Concentration in Aβ Plaques in the APP/PS1 Mouse Model of Alzheimer’s Disease Correlates with Metal Levels in the Surrounding Neuropil

(2016) Simon A. James et al.   ACS Chemical Neuroscience

Als1 and Als3 regulate the intracellular uptake of copper ions when Candida albicans biofilms are exposed to metallic copper surfaces

(2016) Sha Zheng et al.   FEMS YEAST RESEARCH

The Yin and Yang of copper during infection

(2016) Angelique N. Besold et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Interactions of fungal pathogens with phagocytes

(2016) Lars P. Erwig et al.   NATURE REVIEWS MICROBIOLOGY

Candida albicans cell-type switching and functional plasticity in the mammalian host

(2016) Suzanne M. Noble et al.   NATURE REVIEWS MICROBIOLOGY

CsoR Is Essential for Maintaining Copper Homeostasis in Mycobacterium tuberculosis

(2016) Sarah A. Marcus et al.   PLoS One

Host-Imposed Copper Poisoning Impacts Fungal Micronutrient Acquisition during Systemic Candida albicans Infections

(2016) Joanna Mackie et al.   PLoS One

Mycobacterium tuberculosisand Copper: A Newly Appreciated Defense against an Old Foe?

(2015) K. Heran Darwin   JOURNAL OF BIOLOGICAL CHEMISTRY

How to bolster the antifungal pipeline

(2015) D. W. Denning et al.   SCIENCE

Copper binding in IscA inhibits iron-sulphur cluster assembly inEscherichia coli

(2014) Guoqiang Tan et al.   MOLECULAR MICROBIOLOGY

Candida albicans SOD5 represents the prototype of an unprecedented class of Cu-only superoxide dismutases required for pathogen defense

(2014) J. E. Gleason et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Copper-Responsive RicR Regulon Contributes to Mycobacterium tuberculosis Virulence

(2014) X. Shi et al.   mBio

Reciprocal functions of Cryptococcus neoformans copper homeostasis machinery during pulmonary infection and meningoencephalitis

(2014) Tian-Shu Sun et al.   Nature Communications

Cryptococcus neoformans Copper Detoxification Machinery Is Critical for Fungal Virulence

(2013) Chen Ding et al.   Cell Host & Microbe

Regulation of Copper Toxicity by Candida albicans GPA2

(2013) Jennifer A. Schwartz et al.   EUKARYOTIC CELL

Dissecting the Metal Selectivity of MerR Monovalent Metal Ion Sensors in Salmonella

(2013) M. M. Ibanez et al.   JOURNAL OF BACTERIOLOGY

Species-specific activation of Cu/Zn SOD by its CCS copper chaperone in the pathogenic yeast Candida albicans

(2013) Julie E. Gleason et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Copper redistribution in murine macrophages in response toSalmonellainfection

(2012) Maud E. S. Achard et al.   BIOCHEMICAL JOURNAL

Copper in Microbial Pathogenesis: Meddling with the Metal

(2012) Marie I. Samanovic et al.   Cell Host & Microbe

Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Theo Vos et al.   LANCET

Hidden Killers: Human Fungal Infections

(2012) G. D. Brown et al.   Science Translational Medicine

P-Type ATPases

(2011) Michael G. Palmgren et al.   Annual Review of Biophysics

Adaptation of Cryptococcus neoformans to Mammalian Hosts: Integrated Regulation of Metabolism and Virulence

(2011) Jim Kronstad et al.   EUKARYOTIC CELL

The copper regulon of the human fungal pathogen Cryptococcus neoformans H99

(2011) Chen Ding et al.   MOLECULAR MICROBIOLOGY

Expanding fungal pathogenesis: Cryptococcus breaks out of the opportunistic box

(2011) James W. Kronstad et al.   NATURE REVIEWS MICROBIOLOGY

Candida albicans morphogenesis and host defence: discriminating invasion from colonization

(2011) Neil A. R. Gow et al.   NATURE REVIEWS MICROBIOLOGY

Calcium-dependent copper redistributions in neuronal cells revealed by a fluorescent copper sensor and X-ray fluorescence microscopy

(2011) S. C. Dodani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Copper resistance is essential for virulence of Mycobacterium tuberculosis

(2011) F. Wolschendorf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Homeostasis of Iron, Copper, and Zinc in Paracoccidioides Brasiliensis, Cryptococcus Neoformans Var. Grubii, and Cryptococcus Gattii: A Comparative Analysis

(2011) Mirelle Garcia Silva et al.   Frontiers in Microbiology

Cardiac Copper Deficiency Activates a Systemic Signaling Mechanism that Communicates with the Copper Acquisition and Storage Organs

(2010) Byung-Eun Kim et al.   Cell Metabolism

Copper Stress Affects Iron Homeostasis by Destabilizing Iron-Sulfur Cluster Formation in Bacillus subtilis

(2010) S. Chillappagari et al.   JOURNAL OF BACTERIOLOGY

Copper Homeostasis inSalmonellaIs Atypical and Copper-CueP Is a Major Periplasmic Metal Complex

(2010) Deenah Osman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel copper-responsive regulon in Mycobacterium tuberculosis

(2010) Richard A. Festa et al.   MOLECULAR MICROBIOLOGY

CtpV: a putative copper exporter required for full virulence of Mycobacterium tuberculosis

(2010) Sarah K. Ward et al.   MOLECULAR MICROBIOLOGY

Ctr2 Links Copper Homeostasis to Polysaccharide Capsule Formation and Phagocytosis Inhibition in the Human Fungal Pathogen Cryptococcus neoformans

(2010) Cheryl D. Chun et al.   PLoS One

A Role for the ATP7A Copper-transporting ATPase in Macrophage Bactericidal Activity

(2009) Carine White et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Three-dimensional structure of the human copper transporter hCTR1

(2009) C. J. De Feo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of Cu/Zn superoxide dismutase from the heavy-metal-tolerant yeast Cryptococcus liquefaciens strain N6

(2008) Aik-Hong Teh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identification of a copper-binding metallothionein in pathogenic mycobacteria

(2008) Ben Gold et al.   Nature Chemical Biology

Mechanisms for copper acquisition, distribution and regulation

(2008) Byung-Eun Kim et al.   Nature Chemical Biology

Occurrence of Copper Proteins through the Three Domains of Life: A Bioinformatic Approach

(2007) Claudia Andreini et al.   JOURNAL OF PROTEOME RESEARCH