Candida albicans morphogenesis and host defence: discriminating invasion from colonization

The Macrophage-Inducible C-Type Lectin, Mincle, Is an Essential Component of the Innate Immune Response to Candida albicans

(2014) C. A. Wells et al.   JOURNAL OF IMMUNOLOGY

Sch9 Kinase Integrates Hypoxia and CO 2 Sensing To Suppress Hyphal Morphogenesis in Candida albicans

(2011) Catrin Stichternoth et al.   EUKARYOTIC CELL

IL-22 and TNF-α represent a key cytokine combination for epidermal integrity during infection withCandida albicans

(2011) Stefanie Eyerich et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The inflammasome drives protective Th1 and Th17 cellular responses in disseminated candidiasis

(2011) Frank L. van de Veerdonk et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

C. albicans increases cell wall mannoprotein, but not mannan, in response to blood, serum and cultivation at physiological temperature

(2011) M. Kruppa et al.   GLYCOBIOLOGY

Recognition and Blocking of Innate Immunity Cells by Candida albicans Chitin

(2011) Héctor M. Mora-Montes et al.   INFECTION AND IMMUNITY

Interaction of the mucosal barrier with accessory immune cells during fungal infection

(2011) Günther Weindl et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Host–pathogen interactions and virulence-associated genes during Candida albicans oral infections

(2011) Ronny Martin et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Gain-of-function humanSTAT1mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis

(2011) Luyan Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The dectin-1/inflammasome pathway is responsible for the induction of protective T-helper 17 responses that discriminate between yeasts and hyphae of Candida albicans

(2011) Shih-Chin Cheng et al.   JOURNAL OF LEUKOCYTE BIOLOGY

STAT1Mutations in Autosomal Dominant Chronic Mucocutaneous Candidiasis

(2011) Frank L. van de Veerdonk et al.   NEW ENGLAND JOURNAL OF MEDICINE

From Attachment to Damage: Defined Genes of Candida albicans Mediate Adhesion, Invasion and Damage during Interaction with Oral Epithelial Cells

(2011) Betty Wächtler et al.   PLoS One

Chronic Mucocutaneous Candidiasis in Humans with Inborn Errors of Interleukin-17 Immunity

(2011) A. Puel et al.   SCIENCE

A Biphasic Innate Immune MAPK Response Discriminates between the Yeast and Hyphal Forms of Candida albicans in Epithelial Cells

(2010) David L. Moyes et al.   Cell Host & Microbe

Hyphal growth in Candida albicans requires the phosphorylation of Sec2 by the Cdc28-Ccn1/Hgc1 kinase

(2010) Amy Bishop et al.   EMBO JOURNAL

Farnesol Induces Hydrogen Peroxide Resistance in Candida albicans Yeast by Inhibiting the Ras-Cyclic AMP Signaling Pathway

(2010) Aurélie Deveau et al.   EUKARYOTIC CELL

Candida albicans Als3, a Multifunctional Adhesin and Invasin

(2010) Yaoping Liu et al.   EUKARYOTIC CELL

Epithelial Cell-Derived S100 Calcium-Binding Proteins as Key Mediators in the Hallmark Acute Neutrophil Response during Candida Vaginitis

(2010) J. Yano et al.   INFECTION AND IMMUNITY

Impaired TH17 responses in patients with chronic mucocutaneous candidiasis with and without autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy

(2010) Wan-Fai Ng et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

CARD9 Mediates Dectin-2-induced IκBα Kinase Ubiquitination Leading to Activation of NF-κB in Response to Stimulation by the Hyphal Form ofCandida albicans

(2010) Liangkuan Bi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autoantibodies against IL-17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type I

(2010) Anne Puel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokines

(2010) Kai Kisand et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Candida albicans Dampens Host Defense by Downregulating IL-17 Production

(2010) S.-C. Cheng et al.   JOURNAL OF IMMUNOLOGY

Candida albicansHyr1p Confers Resistance to Neutrophil Killing and Is a Potential Vaccine Target

(2010) Guanpingsheng Luo et al.   JOURNAL OF INFECTIOUS DISEASES

Absence of functional TLR4 impairs response of macrophages afterCandida albicansinfection

(2010) Thaís Helena Gasparoto et al.   MEDICAL MYCOLOGY

Thioredoxin Regulates Multiple Hydrogen Peroxide-Induced Signaling Pathways in Candida albicans

(2010) A. da Silva Dantas et al.   MOLECULAR AND CELLULAR BIOLOGY

CO2 Acts as a Signalling Molecule in Populations of the Fungal Pathogen Candida albicans

(2010) Rebecca A. Hall et al.   PLoS Pathogens

Hypoxic Adaptation by Efg1 Regulates Biofilm Formation by Candida albicans

(2009) C. Stichternoth et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

(2009) Ivaylo I. Ivanov et al.   CELL

The Macrophage Mannose Receptor Induces IL-17 in Response to Candida albicans

(2009) Frank L. van de Veerdonk et al.   Cell Host & Microbe

An Essential Role for the NLRP3 Inflammasome in Host Defense against the Human Fungal Pathogen Candida albicans

(2009) Amy G. Hise et al.   Cell Host & Microbe

Candida albicansinternalization by host cells is mediated by a clathrin-dependent mechanism

(2009) Emilia Moreno-Ruiz et al.   CELLULAR MICROBIOLOGY

Cellular interactions ofCandida albicanswith human oral epithelial cells and enterocytes

(2009) Frederic Dalle et al.   CELLULAR MICROBIOLOGY

Milder clinical hyperimmunoglobulin E syndrome phenotype is associated with partial interleukin-17 deficiency

(2009) F. L. van de Veerdonk et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Early Stop Polymorphism in Human DECTIN‐1 Is Associated with IncreasedCandidaColonization in Hematopoietic Stem Cell Transplant Recipients

(2009) Theo S. Plantinga et al.   CLINICAL INFECTIOUS DISEASES

Hsp90 Orchestrates Temperature-Dependent Candida albicans Morphogenesis via Ras1-PKA Signaling

(2009) Rebecca S. Shapiro et al.   CURRENT BIOLOGY

Epithelial GM-CSF Induction by Candida glabrata

(2009) L. Li et al.   JOURNAL OF DENTAL RESEARCH

Evolutionarily conserved recognition and innate immunity to fungal pathogens by the scavenger receptors SCARF1 and CD36

(2009) Terry K. Means et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection

(2009) Matthew J. Robinson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Involvement of the NLRP3 Inflammasome in Innate and Humoral Adaptive Immune Responses to Fungal  -Glucan

(2009) H. Kumar et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Candida albicans Hyphae Formation Triggers Activation of the Nlrp3 Inflammasome

(2009) S. Joly et al.   JOURNAL OF IMMUNOLOGY

Bypassing Pathogen‐Induced Inflammasome Activation for the Regulation of Interleukin‐1β Production by the Fungal PathogenCandida albicans

(2009) Frank L. van de Veerdonk et al.   JOURNAL OF INFECTIOUS DISEASES

Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence

(2009) Olaf Gross et al.   NATURE

Dectin-1 directs T helper cell differentiation by controlling noncanonical NF-κB activation through Raf-1 and Syk

(2009) Sonja I Gringhuis et al.   NATURE IMMUNOLOGY

Human Dectin-1 Deficiency and Mucocutaneous Fungal Infections

(2009) Bart Ferwerda et al.   NEW ENGLAND JOURNAL OF MEDICINE

A HomozygousCARD9Mutation in a Family with Susceptibility to Fungal Infections

(2009) Erik-Oliver Glocker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Bacterial Peptidoglycan Triggers Candida albicans Hyphal Growth by Directly Activating the Adenylyl Cyclase Cyr1p

(2008) Xiao-Li Xu et al.   Cell Host & Microbe

Host Innate Immune Receptors and Beyond: Making Sense of Microbial Infections

(2008) Ken J. Ishii et al.   Cell Host & Microbe

Host–microbe interactions: innate pattern recognition of fungal pathogens

(2008) Frank L van de Veerdonk et al.   CURRENT OPINION IN MICROBIOLOGY

An Internal Polarity Landmark Is Important for Externally Induced Hyphal Behaviors inCandida albicans

(2008) Alexandra Brand et al.   EUKARYOTIC CELL

Generating cell surface diversity inCandida albicansand other fungal pathogens

(2008) Kerstin Nather et al.   FEMS MICROBIOLOGY LETTERS

Genome-wide analysis of Candida albicans gene expression patterns during infection of the mammalian kidney

(2008) Louise A. Walker et al.   FUNGAL GENETICS AND BIOLOGY

Th17 Cell Differentiation: The Long and Winding Road

(2008) Mandy J. McGeachy et al.   IMMUNITY

The Biological Functions of T Helper 17 Cell Effector Cytokines in Inflammation

(2008) Wenjun Ouyang et al.   IMMUNITY

Redundant role of TLR9 for anti-Candida host defense

(2008) F VANDEVEERDONK et al.   IMMUNOBIOLOGY

Microbe sensing, positive feedback loops, and the pathogenesis of inflammatory diseases

(2008) Bruce Beutler   IMMUNOLOGICAL REVIEWS

Dendritic Cell Interaction withCandida albicansCritically Depends onN-Linked Mannan

(2008) Alessandra Cambi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutations inSTAT3andIL12RB1impair the development of human IL-17–producing T cells

(2008) Ludovic de Beaucoudrey et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Colonization of Mice byCandida albicansIs Promoted by Chemically Induced Colitis and Augments Inflammatory Responses through Galectin‐3

(2008) Samir Jawhara et al.   JOURNAL OF INFECTIOUS DISEASES

Patients with Chronic Mucocutaneous Candidiasis Exhibit Reduced Production of Th17-Associated Cytokines IL-17 and IL-22

(2008) Kilian Eyerich et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

ATP drives lamina propria TH17 cell differentiation

(2008) Koji Atarashi et al.   NATURE

Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome

(2008) Joshua D. Milner et al.   NATURE

ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1  and IL-18 secretion in an autocrine way

(2008) A. Piccini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic, Morphotype-Specific Candida albicans β-Glucan Exposure during Infection and Drug Treatment

(2008) Robert T. Wheeler et al.   PLoS Pathogens

Stage-Specific Sampling by Pattern Recognition Receptors during Candida albicans Phagocytosis

(2008) Sigrid E. M. Heinsbroek et al.   PLoS Pathogens

Stimulation of Chitin Synthesis Rescues Candida albicans from Echinocandins

(2008) Louise A. Walker et al.   PLoS Pathogens

Role of TLR1 and TLR6 in the host defense against disseminated candidiasis

(2007) Mihai G. Netea et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

An integrated model of the recognition of Candida albicans by the innate immune system

(2007) Mihai G. Netea et al.   NATURE REVIEWS MICROBIOLOGY