Genome-wide analysis of the regulation of Cu metabolism in Cryptococcus neoformans

Cu-sensing transcription factor Mac1 coordinates with the Ctr transporter family to regulate Cu acquisition and virulence in Aspergillus fumigatus

(2017) Zhendong Cai et al.   FUNGAL GENETICS AND BIOLOGY

Global burden of disease of HIV-associated cryptococcal meningitis: an updated analysis

(2017) Radha Rajasingham et al.   LANCET INFECTIOUS DISEASES

Trojan Horse Transit Contributes to Blood-Brain Barrier Crossing of a Eukaryotic Pathogen

(2017) Felipe H. Santiago-Tirado et al.   mBio

Cryptococcus neoformans Iron-Sulfur Protein Biogenesis Machinery Is a Novel Layer of Protection against Cu Stress

(2017) Sarela Garcia-Santamarina et al.   mBio

Aspergillus fumigatus Copper Export Machinery and Reactive Oxygen Intermediate Defense Counter Host Copper-Mediated Oxidative Antimicrobial Offense

(2017) Philipp Wiemann et al.   Cell Reports

Elucidation of the calcineurin-Crz1 stress response transcriptional network in the human fungal pathogen Cryptococcus neoformans

(2017) Eve W. L. Chow et al.   PLoS Genetics

False friends: Phagocytes as Trojan horses in microbial brain infections

(2017) Felipe H. Santiago-Tirado et al.   PLoS Pathogens

Amino Acid Permeases and Virulence in Cryptococcus neoformans

(2016) Kevin Felipe Cruz Martho et al.   PLoS One

An Adaptation to Low Copper in Candida albicans Involving SOD Enzymes and the Alternative Oxidase

(2016) Chynna N. Broxton et al.   PLoS One

Secretome profiling of Cryptococcus neoformans reveals regulation of a subset of virulence-associated proteins and potential biomarkers by protein kinase A

(2015) Jennifer M. H. Geddes et al.   BMC MICROBIOLOGY

Virulence mechanisms and Cryptococcus neoformans pathogenesis

(2015) J. Andrew Alspaugh   FUNGAL GENETICS AND BIOLOGY

Copper tolerance and virulence in bacteria

(2015) Erik Ladomersky et al.   Metallomics

The Role of Amino Acid Permeases and Tryptophan Biosynthesis in Cryptococcus neoformans Survival

(2015) João Daniel Santos Fernandes et al.   PLoS One

A Genomic Safe Haven for Mutant Complementation in Cryptococcus neoformans

(2015) Samantha D. M. Arras et al.   PLoS One

Candida albicansadapts to host copper during infection by swapping metal cofactors for superoxide dismutase

(2015) Cissy X. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development of Protective Inflammation and Cell-Mediated Immunity against Cryptococcus neoformans after Exposure to Hyphal Mutants

(2015) Bing Zhai et al.   mBio

Systematic functional profiling of transcription factor networks in Cryptococcus neoformans

(2015) Kwang-Woo Jung et al.   Nature Communications

Target or barrier? The cell wall of early- and later-diverging plants vs cadmium toxicity: differences in the response mechanisms

(2015) Luigi Parrotta   Frontiers in Plant Science

VdCYC8, Encoding CYC8 Glucose Repression Mediator Protein, Is Required for Microsclerotia Formation and Full Virulence in Verticillium dahliae

(2015) Zhi-Fang Li et al.   PLoS One

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Exploiting Innate Immune Cell Activation of a Copper-Dependent Antimicrobial Agent during Infection

(2014) Richard A. Festa et al.   CHEMISTRY & BIOLOGY

The Mismetallation of Enzymes during Oxidative Stress

(2014) James A. Imlay   JOURNAL OF BIOLOGICAL CHEMISTRY

Copper binding in IscA inhibits iron-sulphur cluster assembly inEscherichia coli

(2014) Guoqiang Tan et al.   MOLECULAR MICROBIOLOGY

Reciprocal functions of Cryptococcus neoformans copper homeostasis machinery during pulmonary infection and meningoencephalitis

(2014) Tian-Shu Sun et al.   Nature Communications

ChIP-seq and In Vivo Transcriptome Analyses of the Aspergillus fumigatus SREBP SrbA Reveals a New Regulator of the Fungal Hypoxia Response and Virulence

(2014) Dawoon Chung et al.   PLoS Pathogens

Cryptococcus neoformans Copper Detoxification Machinery Is Critical for Fungal Virulence

(2013) Chen Ding et al.   Cell Host & Microbe

A copper hyperaccumulation phenotype correlates with pathogenesis in Cryptococcus neoformans

(2013) Meera R. Raja et al.   Metallomics

Full characterization of the Cu-, Zn-, and Cd-binding properties of CnMT1 and CnMT2, two metallothioneins of the pathogenic fungus Cryptococcus neoformans acting as virulence factors

(2013) Òscar Palacios et al.   Metallomics

The Cryptococcus neoformans Rim101 Transcription Factor Directly Regulates Genes Required for Adaptation to the Host

(2013) T. R. O'Meara et al.   MOLECULAR AND CELLULAR BIOLOGY

Transcriptional remodelling in response to changing copper levels in the Wilson and Menkes disease model of Saccharomyces cerevisiae

(2013) Ayca Cankorur-Cetinkaya et al.   Molecular BioSystems

Charting the travels of copper in eukaryotes from yeast to mammals

(2012) Tracy Nevitt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration

(2012) H. Thorvaldsdottir et al.   BRIEFINGS IN BIOINFORMATICS

Nutritional immunity: transition metals at the pathogen–host interface

(2012) M. Indriati Hood et al.   NATURE REVIEWS MICROBIOLOGY

A Glycosylphosphatidylinositol Anchor Is Required for Membrane Localization but Dispensable for Cell Wall Association of Chitin Deacetylase 2 in Cryptococcus neoformans

(2012) N. M. Gilbert et al.   mBio

The Link between Morphotype Transition and Virulence in Cryptococcus neoformans

(2012) Linqi Wang et al.   PLoS Pathogens

A Major Role for Capsule-Independent Phagocytosis-Inhibitory Mechanisms in Mammalian Infection by Cryptococcus neoformans

(2011) Cheryl D. Chun et al.   Cell Host & Microbe

Adaptation of Cryptococcus neoformans to Mammalian Hosts: Integrated Regulation of Metabolism and Virulence

(2011) Jim Kronstad et al.   EUKARYOTIC CELL

The copper regulon of the human fungal pathogen Cryptococcus neoformans H99

(2011) Chen Ding et al.   MOLECULAR MICROBIOLOGY

Integrative genomics viewer

(2011) James T Robinson et al.   NATURE BIOTECHNOLOGY

Systems Biology Approach inChlamydomonasReveals Connections between Copper Nutrition and Multiple Metabolic Steps

(2011) Madeli Castruita et al.   PLANT CELL

Copper resistance is essential for virulence of Mycobacterium tuberculosis

(2011) F. Wolschendorf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SREBP Coordinates Iron and Ergosterol Homeostasis to Mediate Triazole Drug and Hypoxia Responses in the Human Fungal Pathogen Aspergillus fumigatus

(2011) Michael Blatzer et al.   PLoS Genetics

On the role of the cell wall in the phenomenon of copper tolerance in Silene paradoxa L.

(2010) Ilaria Colzi et al.   ENVIRONMENTAL AND EXPERIMENTAL BOTANY

Cryptococcus neoformans Histone Acetyltransferase Gcn5 Regulates Fungal Adaptation to the Host

(2010) Teresa R. O'Meara et al.   EUKARYOTIC CELL

The Multi-Copper-Ion Oxidase CueO of Salmonella enterica Serovar Typhimurium Is Required for Systemic Virulence

(2010) M. E. S. Achard et al.   INFECTION AND IMMUNITY

Transcription Factors Mat2 and Znf2 Operate Cellular Circuits Orchestrating Opposite- and Same-Sex Mating in Cryptococcus neoformans

(2010) Xiaorong Lin et al.   PLoS Genetics

HapX Positively and Negatively Regulates the Transcriptional Response to Iron Deprivation in Cryptococcus neoformans

(2010) Won Hee Jung et al.   PLoS Pathogens

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Remodeling of Global Transcription Patterns ofCryptococcus neoformansGenes Mediated by the Stress-Activated HOG Signaling Pathways

(2009) Young-Joon Ko et al.   EUKARYOTIC CELL

A copper-responsive factor geneCUF1 is required for copper induction of laccase inCryptococcus neoformans

(2009) Nan Jiang et al.   FEMS MICROBIOLOGY LETTERS

A Role for the ATP7A Copper-transporting ATPase in Macrophage Bactericidal Activity

(2009) Carine White et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cryptococcus neoformansSite-2 protease is required for virulence and survival in the presence of azole drugs

(2009) Clara M. Bien et al.   MOLECULAR MICROBIOLOGY

MEME SUITE: tools for motif discovery and searching

(2009) T. L. Bailey et al.   NUCLEIC ACIDS RESEARCH

The iron-sulfur clusters of dehydratases are primary intracellular targets of copper toxicity

(2009) L. Macomber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Formulation of a Defined V8 Medium for Induction of Sexual Development of Cryptococcus neoformans

(2008) C. R. Kent et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Impact of cell wall structure on the behavior of bacterial cells in the binding of copper and cadmium

(2008) Linchuan Fang et al.   COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS

Impact of Mating Type, Serotype, and Ploidy on the Virulence of Cryptococcus neoformans

(2008) X. Lin et al.   INFECTION AND IMMUNITY

Copper-dependent transcriptional regulation by Candida albicans Mac1p

(2008) A. Woodacre et al.   MICROBIOLOGY-SGM

Iron Source Preference and Regulation of Iron Uptake in Cryptococcus neoformans

(2008) Won Hee Jung et al.   PLoS Pathogens

Patterns of Correlation of Plasma Ceruloplasmin in Sepsis

(2007) Carlo Chiarla et al.   JOURNAL OF SURGICAL RESEARCH