LAR and PTPσ receptors are negative regulators of oligodendrogenesis and oligodendrocyte integrity in spinal cord injury

Perturbing chondroitin sulfate proteoglycan signaling through LAR and PTPσ receptors promotes a beneficial inflammatory response following spinal cord injury

(2018) Scott Dyck et al.   Journal of Neuroinflammation

Neuregulin-1 positively modulates glial response and improves neurological recovery following traumatic spinal cord injury

(2017) Arsalan Alizadeh et al.   GLIA

Neuregulin-1 promotes remyelination and fosters a pro-regenerative inflammatory response in focal demyelinating lesions of the spinal cord

(2017) Hardeep Kataria et al.   GLIA

Microenvironmental regulation of oligodendrocyte replacement and remyelination in spinal cord injury

(2016) Arsalan Alizadeh et al.   JOURNAL OF PHYSIOLOGY-LONDON

High-throughput proteomics reveal alarmins as amplifiers of tissue pathology and inflammation after spinal cord injury

(2016) Athanasios Didangelos et al.   Scientific Reports

Two PTP receptors mediate CSPG inhibition by convergent and divergent signaling pathways in neurons

(2016) Yosuke Ohtake et al.   Scientific Reports

Chondroitin sulfate proteoglycans: Key modulators in the developing and pathologic central nervous system

(2015) Scott M. Dyck et al.   EXPERIMENTAL NEUROLOGY

Interleukin-10 is a critical regulator of white matter lesion containment following viral induced demyelination

(2015) Shweta S. Puntambekar et al.   GLIA

Chronic Oligodendrogenesis and Remyelination after Spinal Cord Injury in Mice and Rats

(2015) Z. C. Hesp et al.   JOURNAL OF NEUROSCIENCE

Chondroitin Sulfate Proteoglycans Negatively Modulate Spinal Cord Neural Precursor Cells by Signaling Through LAR and RPTPσ and Modulation of the Rho/ROCK Pathway

(2015) Scott M. Dyck et al.   STEM CELLS

Myelin damage and repair in pathologic CNS: challenges and prospects

(2015) Arsalan Alizadeh et al.   Frontiers in Molecular Neuroscience

Functional regeneration beyond the glial scar

(2014) Jared M. Cregg et al.   EXPERIMENTAL NEUROLOGY

Regulation of IL-10 by Chondroitinase ABC Promotes a Distinct Immune Response following Spinal Cord Injury

(2014) Athanasios Didangelos et al.   JOURNAL OF NEUROSCIENCE

Modulation of the proteoglycan receptor PTPσ promotes recovery after spinal cord injury

(2014) Bradley T. Lang et al.   NATURE

Dysregulation of the neuregulin-1-ErbB network modulates endogenous oligodendrocyte differentiation and preservation after spinal cord injury

(2013) Marie-Krystel Gauthier et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The Rho-kinase inhibitor fasudil restores normal motor nerve conduction velocity in diabetic rats by assuring the proper localization of adhesion-related molecules in myelinating Schwann cells

(2013) Yasushi Kanazawa et al.   EXPERIMENTAL NEUROLOGY

Chondroitin sulfate proteoglycans inhibit oligodendrocyte myelination through PTPσ

(2013) James C. Pendleton et al.   EXPERIMENTAL NEUROLOGY

Selective expression of CSPG receptors PTPσ and LAR in poorly regenerating reticulospinal neurons of lamprey

(2013) Guixin Zhang et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Resident Neural Stem Cells Restrict Tissue Damage and Neuronal Loss After Spinal Cord Injury in Mice

(2013) H. Sabelstrom et al.   SCIENCE

Chondroitin sulfate proteoglycans in demyelinated lesions impair remyelination

(2012) Lorraine W. Lau et al.   ANNALS OF NEUROLOGY

The Delayed Post-Injury Administration of Soluble Fas Receptor Attenuates Post-Traumatic Neural Degeneration and Enhances Functional Recovery after Traumatic Cervical Spinal Cord Injury

(2012) Sherri Robins-Steele et al.   JOURNAL OF NEUROTRAUMA

Chondroitinase and Growth Factors Enhance Activation and Oligodendrocyte Differentiation of Endogenous Neural Precursor Cells after Spinal Cord Injury

(2012) Soheila Karimi-Abdolrezaee et al.   PLoS One

Delayed treatment with Chondroitinase ABC reverses chronic atrophy of rubrospinal neurons following spinal cord injury

(2011) Lucy M. Carter et al.   EXPERIMENTAL NEUROLOGY

Chondroitinase treatment following spinal contusion injury increases migration of oligodendrocyte progenitor cells

(2011) Justin R. Siebert et al.   EXPERIMENTAL NEUROLOGY

Leukocyte Common Antigen-Related Phosphatase Is a Functional Receptor for Chondroitin Sulfate Proteoglycan Axon Growth Inhibitors

(2011) D. Fisher et al.   JOURNAL OF NEUROSCIENCE

Functional regeneration of respiratory pathways after spinal cord injury

(2011) Warren J. Alilain et al.   NATURE

Repertoire of microglial and macrophage responses after spinal cord injury

(2011) Samuel David et al.   NATURE REVIEWS NEUROSCIENCE

Origin of New Glial Cells in Intact and Injured Adult Spinal Cord

(2010) Fanie Barnabé-Heider et al.   Cell Stem Cell

Synergistic Effects of Transplanted Adult Neural Stem/Progenitor Cells, Chondroitinase, and Growth Factors Promote Functional Repair and Plasticity of the Chronically Injured Spinal Cord

(2010) S. Karimi-Abdolrezaee et al.   JOURNAL OF NEUROSCIENCE

Rho-Associated Kinase II (ROCKII) Limits Axonal Growth after Trauma within the Adult Mouse Spinal Cord

(2009) P. Duffy et al.   JOURNAL OF NEUROSCIENCE

Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis

(2008) T. Kuhlmann et al.   BRAIN

Stem Cells for Spinal Cord Repair

(2008) Fanie Barnabé-Heider et al.   Cell Stem Cell

The life, death, and replacement of oligodendrocytes in the adult CNS

(2008) Dana M. McTigue et al.   JOURNAL OF NEUROCHEMISTRY

Cell Death after Spinal Cord Injury Is Exacerbated by Rapid TNF -Induced Trafficking of GluR2-Lacking AMPARs to the Plasma Membrane

(2008) A. R. Ferguson et al.   JOURNAL OF NEUROSCIENCE

The Yellow Fluorescent Protein (YFP-H) Mouse Reveals Neuroprotection as a Novel Mechanism Underlying Chondroitinase ABC-Mediated Repair after Spinal Cord Injury

(2008) L. M. Carter et al.   JOURNAL OF NEUROSCIENCE

Spinal Cord Injury Reveals Multilineage Differentiation of Ependymal Cells

(2008) Konstantinos Meletis et al.   PLOS BIOLOGY