Neuregulin-1 positively modulates glial response and improves neurological recovery following traumatic spinal cord injury

Neuregulin-1 controls an endogenous repair mechanism after spinal cord injury

(2016) Katalin Bartus et al.   BRAIN

Regulation of inflammatory responses by neuregulin-1 in brain ischemia and microglial cells in vitro involves the NF-kappa B pathway

(2016) Lauren J. Simmons et al.   Journal of Neuroinflammation

Monocyte-Derived Macrophages Contribute to Spontaneous Long-Term Functional Recovery after Stroke in Mice

(2016) S. Wattananit et al.   JOURNAL OF NEUROSCIENCE

Quantitative Phosphoproteomics Analysis of ERBB3/ERBB4 Signaling

(2016) Sebastian K. Wandinger et al.   PLoS One

Age decreases macrophage IL-10 expression: Implications for functional recovery and tissue repair in spinal cord injury

(2015) Bei Zhang et al.   EXPERIMENTAL NEUROLOGY

Chondroitin sulfate proteoglycans: Key modulators in the developing and pathologic central nervous system

(2015) Scott M. Dyck et al.   EXPERIMENTAL NEUROLOGY

Interleukin-10 is a critical regulator of white matter lesion containment following viral induced demyelination

(2015) Shweta S. Puntambekar et al.   GLIA

Neuregulin-1 inhibits neuroinflammatory responses in a rat model of organophosphate-nerve agent-induced delayed neuronal injury

(2015) Yonggang Li et al.   Journal of Neuroinflammation

Chondroitin Sulfate Proteoglycans Negatively Modulate Spinal Cord Neural Precursor Cells by Signaling Through LAR and RPTPσ and Modulation of the Rho/ROCK Pathway

(2015) Scott M. Dyck et al.   STEM CELLS

Myelin damage and repair in pathologic CNS: challenges and prospects

(2015) Arsalan Alizadeh et al.   Frontiers in Molecular Neuroscience

TLR-mediated STAT3 and ERK activation controls IL-10 secretion by human B cells

(2014) Bi-Sheng Liu et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

TGFβ produced by IL-10 redirected astrocytes attenuates microglial activation

(2014) Diana M. Norden et al.   GLIA

Signaling through MyD88 Regulates Leukocyte Recruitment after Brain Injury

(2014) A. A. Babcock et al.   JOURNAL OF IMMUNOLOGY

Neuregulin 1-Induced AKT and ERK Phosphorylation in Patients with Fragile X Syndrome (FXS) and Intellectual Disability Associated with Obstetric Complications

(2014) Tamás Kovács et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

TNF and Increased Intracellular Iron Alter Macrophage Polarization to a Detrimental M1 Phenotype in the Injured Spinal Cord

(2014) Antje Kroner et al.   NEURON

Toll-Like Receptors 2, -3 and -4 Prime Microglia but not Astrocytes Across Central Nervous System Regions for ATP-Dependent Interleukin-1β Release

(2014) Laura Facci et al.   Scientific Reports

The IL-10/STAT3-mediated anti-inflammatory response: recent developments and future challenges

(2013) A. P. Hutchins et al.   Briefings in Functional Genomics

Dysregulation of the neuregulin-1-ErbB network modulates endogenous oligodendrocyte differentiation and preservation after spinal cord injury

(2013) Marie-Krystel Gauthier et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Elevated MMP-9 in the Lumbar Cord Early after Thoracic Spinal Cord Injury Impedes Motor Relearning in Mice

(2013) C. N. Hansen et al.   JOURNAL OF NEUROSCIENCE

The Therapeutic Role of Interleukin-10 after Spinal Cord Injury

(2013) Colton D. Thompson et al.   JOURNAL OF NEUROTRAUMA

Time-dependent regulation of neuregulin-1β/ErbB/ERK pathways in cardiac differentiation of mouse embryonic stem cells

(2013) Ming Chen et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination

(2013) Veronique E Miron et al.   NATURE NEUROSCIENCE

Neuregulin Upregulates Microglial α7 Nicotinic Acetylcholine Receptor Expression in Immortalized Cell Lines: Implications for Regulating Neuroinflammation

(2013) Malwina Mencel et al.   PLoS One

ErbB1-4-dependent EGF/neuregulin signals and their cross talk in the central nervous system: pathological implications in schizophrenia and Parkinson's disease

(2013) Yuriko Iwakura et al.   Frontiers in Cellular Neuroscience

Chondroitin sulfate proteoglycans in demyelinated lesions impair remyelination

(2012) Lorraine W. Lau et al.   ANNALS OF NEUROLOGY

Interleukin-1 participates in the classical and alternative activation of microglia/macrophages after spinal cord injury

(2012) Atsushi Sato et al.   Journal of Neuroinflammation

Reactive Astrogliosis after Spinal Cord Injury—Beneficial and Detrimental Effects

(2012) Soheila Karimi-Abdolrezaee et al.   MOLECULAR NEUROBIOLOGY

Chondroitinase and Growth Factors Enhance Activation and Oligodendrocyte Differentiation of Endogenous Neural Precursor Cells after Spinal Cord Injury

(2012) Soheila Karimi-Abdolrezaee et al.   PLoS One

Role of Neuregulin-1/ErbB Signaling in Stem Cell Therapy for Spinal Cord Injury-Induced Chronic Neuropathic Pain

(2012) Feng Tao et al.   STEM CELLS

Following nerve injury neuregulin-1 drives microglial proliferation and neuropathic pain via the MEK/ERK pathway

(2011) Margarita Calvo et al.   GLIA

Astrocytes from the Contused Spinal Cord Inhibit Oligodendrocyte Differentiation of Adult Oligodendrocyte Precursor Cells by Increasing the Expression of Bone Morphogenetic Proteins

(2011) Y. Wang et al.   JOURNAL OF NEUROSCIENCE

Reactive Astrocytes Inhibit the Survival and Differentiation of Oligodendrocyte Precursor Cells by Secreted TNF-α

(2011) Zhida Su et al.   JOURNAL OF NEUROTRAUMA

Repertoire of microglial and macrophage responses after spinal cord injury

(2011) Samuel David et al.   NATURE REVIEWS NEUROSCIENCE

Cell type-specific regulation of IL-10 expression in inflammation and disease

(2010) Christian M. Hedrich et al.   IMMUNOLOGIC RESEARCH

Prolonged activation of ERK triggers glutamate-induced apoptosis of astrocytes: neuroprotective effect of FK506

(2010) Kinga Szydlowska et al.   JOURNAL OF NEUROCHEMISTRY

Cerebral ischemia induces micro vascular pro-inflammatory cytokine expression via the MEK/ERK pathway

(2010) Aida Maddahi et al.   Journal of Neuroinflammation

Soluble Neuregulin-1 Has Bifunctional, Concentration-Dependent Effects on Schwann Cell Myelination

(2010) N. Syed et al.   JOURNAL OF NEUROSCIENCE

Synergistic Effects of Transplanted Adult Neural Stem/Progenitor Cells, Chondroitinase, and Growth Factors Promote Functional Repair and Plasticity of the Chronically Injured Spinal Cord

(2010) S. Karimi-Abdolrezaee et al.   JOURNAL OF NEUROSCIENCE

Signals to promote myelin formation and repair

(2010) Carla Taveggia et al.   Nature Reviews Neurology

Reactive astrocytes as therapeutic targets for CNS disorders

(2010) Mary E. Hamby et al.   Neurotherapeutics

Astrocytes initiate inflammation in the injured mouse spinal cord by promoting the entry of neutrophils and inflammatory monocytes in an IL-1 receptor/MyD88-dependent fashion

(2009) Isabelle Pineau et al.   BRAIN BEHAVIOR AND IMMUNITY

IL-10 promotes neuronal survival following spinal cord injury

(2009) Zhigang Zhou et al.   EXPERIMENTAL NEUROLOGY

Interleukin-10 Production by Th1 Cells Requires Interleukin-12-Induced STAT4 Transcription Factor and ERK MAP Kinase Activation by High Antigen Dose

(2009) Margarida Saraiva et al.   IMMUNITY

Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord

(2009) K. A. Kigerl et al.   JOURNAL OF NEUROSCIENCE

Molecular dissection of reactive astrogliosis and glial scar formation

(2009) Michael V. Sofroniew   TRENDS IN NEUROSCIENCES

α4β1 integrin blockade after spinal cord injury decreases damage and improves neurological function

(2008) Jennifer C. Fleming et al.   EXPERIMENTAL NEUROLOGY

Effect of Neuregulin on Apoptosis and Expressions of STAT3 and GFAP in Rats Following Cerebral Ischemic Reperfusion

(2008) Qin Li et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Matrix Metalloproteinase-9 Facilitates Glial Scar Formation in the Injured Spinal Cord

(2008) J.-Y. C. Hsu et al.   JOURNAL OF NEUROSCIENCE

Type III Neuregulin-1 Is Required for Normal Sensorimotor Gating, Memory-Related Behaviors, and Corticostriatal Circuit Components

(2008) Y.-J. J. Chen et al.   JOURNAL OF NEUROSCIENCE

Cell Death after Spinal Cord Injury Is Exacerbated by Rapid TNF -Induced Trafficking of GluR2-Lacking AMPARs to the Plasma Membrane

(2008) A. R. Ferguson et al.   JOURNAL OF NEUROSCIENCE

Neuregulin 1 in neural development, synaptic plasticity and schizophrenia

(2008) Lin Mei et al.   NATURE REVIEWS NEUROSCIENCE

Inflammation and its role in neuroprotection, axonal regeneration and functional recovery after spinal cord injury

(2007) Dustin J. Donnelly et al.   EXPERIMENTAL NEUROLOGY