Can alternative epitope mapping approaches increase the impact of B-cell epitopes in food allergy diagnostics?

A new luminex-based peptide assay to identify reactivity to baked, fermented and whole milk

(2018) Cansin Sackesen et al.   ALLERGY

The pathophysiology of anaphylaxis

(2017) Laurent L. Reber et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Application of phage peptide display technology for the study of food allergen epitopes

(2017) Xueni Chen et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Modeling protein quaternary structure of homo- and hetero-oligomers beyond binary interactions by homology

(2017) Martino Bertoni et al.   Scientific Reports

Conformational IgE epitopes of peanut allergens Ara h 2 and Ara h 6

(2016) X. Chen et al.   CLINICAL AND EXPERIMENTAL ALLERGY

The conformational IgE epitope profile of soya bean allergen Gly m 4

(2016) F. Husslik et al.   CLINICAL AND EXPERIMENTAL ALLERGY

pH and heat induced structural changes of chicken ovalbumin in relation with antigenic properties

(2016) Nicoleta Stănciuc et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Monitoring the epitope recognition profiles of IgE, IgG 1 , and IgG 4 during birch pollen immunotherapy

(2016) Barbara Gepp et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Single B-cell deconvolution of peanut-specific antibody responses in allergic patients

(2016) Ramona A. Hoh et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Epitope Mapping of Rhi o 1 and Generation of a Hypoallergenic Variant

(2016) Gaurab Sircar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effect of Avoidance on Peanut Allergy after Early Peanut Consumption

(2016) George Du Toit et al.   NEW ENGLAND JOURNAL OF MEDICINE

The SWISS-MODEL Repository—new features and functionality

(2016) Stefan Bienert et al.   NUCLEIC ACIDS RESEARCH

IgE+ B cells are scarce, but allergen-specific B cells with a memory phenotype circulate in patients with allergic rhinitis

(2015) K. J. Wong et al.   ALLERGY

Screening and identification of mimotopes of the major shrimp allergen tropomyosin using one-bead-one-compound peptide libraries

(2015) Nicki YH Leung et al.   Cellular & Molecular Immunology

Epitope analysis of Ara h 2 and Ara h 6: characteristic patterns of IgE-binding fingerprints among individuals with similar clinical histories

(2015) K. Otsu et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Identification of novel peptide biomarkers to predict safety and efficacy of cow's milk oral immunotherapy by peptide microarray

(2015) J. Martínez-Botas et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Diagnostic accuracy of specific IgE to components in diagnosing peanut allergy: a systematic review

(2015) R. J. B. Klemans et al.   CLINICAL AND EXPERIMENTAL ALLERGY

MicroRNA regulation of allergic inflammation and asthma

(2015) Heather H Pua et al.   CURRENT OPINION IN IMMUNOLOGY

In vitro assessment of allergenicity features and localization of probable IgE binding regions

(2015) Ankita Mishra et al.   FOOD AND CHEMICAL TOXICOLOGY

Platelet activating factor in allergies

(2015) Krzysztof Pałgan et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Allergenicity of peanut component Ara h 2: Contribution of conformational versus linear hydroxyproline-containing epitopes

(2015) Hervé Bernard et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IgG4 inhibits peanut-induced basophil and mast cell activation in peanut-tolerant children sensitized to peanut major allergens

(2015) Alexandra F. Santos et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Peanut oral immunotherapy transiently expands circulating Ara h 2–specific B cells with a homologous repertoire in unrelated subjects

(2015) Sarita U. Patil et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Epitope mapping of 7S cashew antigen in complex with antibody by solution-phase H/D exchange monitored by FT-ICR mass spectrometry

(2015) Xiaoyan Guan et al.   JOURNAL OF MASS SPECTROMETRY

Randomized Trial of Peanut Consumption in Infants at Risk for Peanut Allergy

(2015) George Du Toit et al.   NEW ENGLAND JOURNAL OF MEDICINE

Clinical Management of Food Allergy

(2015) J. Andrew Bird et al.   Journal of Allergy and Clinical Immunology-In Practice

Risk multipliers for severe food anaphylaxis

(2015) Peter K Smith et al.   World Allergy Organization Journal

Down-Regulation of MicroRNA-223 Promotes Degranulation via the PI3K/Akt Pathway by Targeting IGF-1R in Mast Cells

(2015) Quan Wang et al.   PLoS One

Human IgE+ B cells are derived from T cell–dependent and T cell–independent pathways

(2014) Magdalena A. Berkowska et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information

(2014) Marco Biasini et al.   NUCLEIC ACIDS RESEARCH

Effect of heat treatment on milk and egg proteins allergenicity

(2014) Katherine A. Bloom et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Use of IgE and IgG4 epitope binding to predict the outcome of oral immunotherapy in cow's milk allergy

(2014) Emma M. Savilahti et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

A systematic review of the effect of thermal processing on the allergenicity of tree nuts

(2013) L. J. Masthoff et al.   ALLERGY

miR-142-3p enhances FcεRI-mediated degranulation in mast cells

(2013) Yoji Yamada et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regulation of IgE-mediated signalling in human basophils by CD32b and its role in Syk down-regulation

(2013) D. MacGlashan et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Evaluating pH-Induced Gastrointestinal Aggregation of Arachis hypogaea 1 Fragments as Potential Components of Peanut Allergy

(2013) I. John Khan et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The enigma of IgE+ B-cell memory in human subjects

(2013) Janet M. Davies et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Epitope specificity determines pathogenicity and detectability in ANCA-associated vasculitis

(2013) Aleeza J. Roth et al.   JOURNAL OF CLINICAL INVESTIGATION

Conformational epitope mapping of Pru du 6, a major allergen from almond nut

(2013) LeAnna N. Willison et al.   MOLECULAR IMMUNOLOGY

IgE versus IgG4 epitopes of the peanut allergen Ara h 1 in patients with severe allergy

(2013) K.L. Bøgh et al.   MOLECULAR IMMUNOLOGY

Evidence of pathway-specific basophil anergy induced by peanut oral immunotherapy in peanut-allergic children

(2012) A. Thyagarajan et al.   CLINICAL AND EXPERIMENTAL ALLERGY

A bioinformatics approach to identify patients with symptomatic peanut allergy using peptide microarray immunoassay

(2012) Jing Lin et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Peanut oral immunotherapy modifies IgE and IgG4 responses to major peanut allergens

(2012) Brian P. Vickery et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IgE epitopes of intact and digested Ara h 1: A comparative study in humans and rats

(2012) K.L. Bøgh et al.   MOLECULAR IMMUNOLOGY

Ara h 1 structure is retained after roasting and is important for enhanced binding to IgE

(2012) Jacqueline B. Nesbit et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Identification of Critical Amino Acids in an Immunodominant IgE Epitope of Pen c 13, a Major Allergen from Penicillium citrinum

(2012) Jui-Chieh Chen et al.   PLoS One

Mapping IgE binding epitopes of major shrimp (Penaeus monodon) allergen with immunoinformatics tools

(2011) Li-Na Zheng et al.   FOOD AND CHEMICAL TOXICOLOGY

Generation and epitope analysis of human monoclonal antibody isotypes with specificity for the timothy grass major allergen Phl p 5a

(2011) Julia Hecker et al.   MOLECULAR IMMUNOLOGY

MiR-221 Influences Effector Functions and Actin Cytoskeleton in Mast Cells

(2011) Ramon J. Mayoral et al.   PLoS One

Identification of amino acids critical for IgE-binding to sequential epitopes of bovine κ-casein and the similarity of these epitopes to the corresponding human κ-casein sequence

(2010) N. Han et al.   ALLERGY

The role of hen’s egg-specific IgE, IgG and IgG4 in the diagnostic procedure of hen’s egg allergy

(2010) B. Ahrens et al.   ALLERGY

Individualized IgE-based dosing of egg oral immunotherapy and the development of tolerance

(2010) Brian P. Vickery et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Toward the estimation of the absolute quality of individual protein structure models

(2010) Pascal Benkert et al.   BIOINFORMATICS

Automated comparative protein structure modeling with SWISS-MODEL and Swiss-PdbViewer: A historical perspective

(2010) Nicolas Guex et al.   ELECTROPHORESIS

Identification of an IgE-Binding Epitope of a Major Buckwheat Allergen, BWp16, by SPOTs Assay and Mimotope Screening

(2010) Rie Satoh et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Early recovery from cow's milk allergy is associated with decreasing IgE and increasing IgG4 binding to cow's milk epitopes

(2010) Emma M. Savilahti et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Correlation of IgE/IgG4 milk epitopes and affinity of milk-specific IgE antibodies with different phenotypes of clinical milk allergy

(2010) Julie Wang et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Digestion of peanut allergens Ara h 1, Ara h 2, Ara h 3, and Ara h 6: A comparative in vitro study and partial characterization of digestion-resistant peptides

(2010) Stef J. Koppelman et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Relevant B Cell Epitopes in Allergic Disease

(2009) Anna Pomés   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Allergen-specific basophil suppression associated with clinical tolerance in patients with milk allergy

(2009) Niya Wanich et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Clinical efficacy and immune regulation with peanut oral immunotherapy

(2009) Stacie M. Jones et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

High-Affinity IgE Recognition of a Conformational Epitope of the Major Respiratory Allergen Phl p 2 As Revealed by X-Ray Crystallography

(2009) S. Padavattan et al.   JOURNAL OF IMMUNOLOGY

IgE-binding epitopic peptide mapping on a three-dimensional model built for the 13S globulin allergen of buckwheat (Fagopyrum esculentum)

(2009) Camille Sordet et al.   PEPTIDES

Peripheral B cell subsets

(2008) David Allman et al.   CURRENT OPINION IN IMMUNOLOGY

Determination of Pepsin-Susceptible and Pepsin-Resistant Epitopes in Native and Heat-Treated Peanut Allergen Ara h 1

(2008) Evelien L. van Boxtel et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Several distinct properties of the IgE repertoire determine effector cell degranulation in response to allergen challenge

(2008) Lars Harder Christensen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Peanut epitopes for IgE and IgG4 in peanut-sensitized children in relation to severity of peanut allergy

(2008) Annebeth E. Flinterman et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The role of protein digestibility and antacids on food allergy outcomes

(2008) Eva Untersmayr et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mapping of the IgE and IgG4 sequential epitopes of milk allergens with a peptide microarray–based immunoassay

(2008) Inmaculada Cerecedo et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mapping and conformational analysis of IgE-binding epitopic regions on the molecular surface of the major Ara h 3 legumin allergen of peanut (Arachis hypogaea)

(2008) Pierre Rougé et al.   MOLECULAR IMMUNOLOGY

Platelet-Activating Factor, PAF Acetylhydrolase, and Severe Anaphylaxis

(2008) Peter Vadas et al.   NEW ENGLAND JOURNAL OF MEDICINE

Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning

(2007) Thomas Tiller et al.   JOURNAL OF IMMUNOLOGICAL METHODS