Misdelivery at the Nuclear Pore Complex—Stopping a Virus Dead in Its Tracks

Co-option of Membrane Wounding Enables Virus Penetration into Cells

(2015) Stefania Luisoni et al.   Cell Host & Microbe

Intracellular detection of viral nucleic acids

(2015) Konstantin MJ Sparrer et al.   CURRENT OPINION IN MICROBIOLOGY

Cellular Innate Immunity and Restriction of Viral Infection: Implications for Lentiviral Gene Therapy in Human Hematopoietic Cells

(2015) Anna Kajaste-Rudnitski et al.   HUMAN GENE THERAPY

A Triple-Arginine Motif in the Amino-Terminal Domain and Oligomerization Are Required for HIV-1 Inhibition by Human MX2

(2015) Caroline Goujon et al.   JOURNAL OF VIROLOGY

Influenza Virus-Induced Caspase-Dependent Enlargement of Nuclear Pores Promotes Nuclear Export of Viral Ribonucleoprotein Complexes

(2015) Dirk Mühlbauer et al.   JOURNAL OF VIROLOGY

Distribution of DNA-condensing protein complexes in the adenovirus core

(2015) Ana J. Pérez-Berná et al.   NUCLEIC ACIDS RESEARCH

Architecture of the nuclear pore complex coat

(2015) T. Stuwe et al.   SCIENCE

Early IFN type I response: Learning from microbial evasion strategies

(2015) Eliana M. Coccia et al.   SEMINARS IN IMMUNOLOGY

RNA degradation in antiviral immunity and autoimmunity

(2015) Rachel E. Rigby et al.   TRENDS IN IMMUNOLOGY

Interferons and viruses: an evolutionary arms race of molecular interactions

(2015) Hans-Heinrich Hoffmann et al.   TRENDS IN IMMUNOLOGY

DNA virus uncoating

(2015) Samuel Kilcher et al.   VIROLOGY

Innate immune recognition of DNA: A recent history

(2015) Alan Dempsey et al.   VIROLOGY

Old foes, new understandings: nuclear entry of small non-enveloped DNA viruses

(2015) Nikta Fay et al.   Current Opinion in Virology

Importin-β modulates the permeability of the nuclear pore complex in a Ran-dependent manner

(2015) Alan R Lowe et al.   eLife

Nup98 FG domains from diverse species spontaneously phase-separate into particles with nuclear pore-like permselectivity

(2015) Hermann Broder Schmidt et al.   eLife

Cellular Sensing of Viral DNA and Viral Evasion Mechanisms

(2014) Megan H. Orzalli et al.   Annual Review of Microbiology

How Cells Tune Viral Mechanics—Insights from Biophysical Measurements of Influenza Virus

(2014) Urs F. Greber   BIOPHYSICAL JOURNAL

Structural Insight into HIV-1 Restriction by MxB

(2014) Jennifer L. Fribourgh et al.   Cell Host & Microbe

Innate Immunity to Adenovirus

(2014) Rodinde Hendrickx et al.   HUMAN GENE THERAPY

Chemical Induction of Unfolded Protein Response Enhances Cancer Cell Killing through Lytic Virus Infection

(2014) V. Prasad et al.   JOURNAL OF VIROLOGY

Nuclear Import of Adenovirus DNA Involves Direct Interaction of Hexon with an N-Terminal Domain of the Nucleoporin Nup214

(2014) Aurélia Cassany et al.   JOURNAL OF VIROLOGY

Host and Viral Determinants of Mx2 Antiretroviral Activity

(2014) Idoia Busnadiego et al.   JOURNAL OF VIROLOGY

Transfer of the Amino-Terminal Nuclear Envelope Targeting Domain of Human MX2 Converts MX1 into an HIV-1 Resistance Factor

(2014) C. Goujon et al.   JOURNAL OF VIROLOGY

HIV-1 Uncoating Is Facilitated by Dynein and Kinesin 1

(2014) Z. Lukic et al.   JOURNAL OF VIROLOGY

The STING controlled cytosolic-DNA activated innate immune pathway and microbial disease

(2014) Hiroyasu Konno et al.   MICROBES AND INFECTION

At the centre: influenza A virus ribonucleoproteins

(2014) Amie J. Eisfeld et al.   NATURE REVIEWS MICROBIOLOGY

Host and viral determinants for MxB restriction of HIV-1 infection

(2014) Kenneth A Matreyek et al.   Retrovirology

Targeting of Viral Capsids to Nuclear Pores in a Cell-Free Reconstitution System

(2014) Fenja Anderson et al.   TRAFFIC

HIV-1 uncoating: connection to nuclear entry and regulation by host proteins

(2014) Zandrea Ambrose et al.   VIROLOGY

Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly

(2014) Amanda J. Price et al.   PLoS Pathogens

Quantitative microscopy of functional HIV post-entry complexes reveals association of replication with the viral capsid

(2014) Ke Peng et al.   eLife

Tracking Viral Genomes in Host Cells at Single-Molecule Resolution

(2013) I-Hsuan Wang et al.   Cell Host & Microbe

The Interferon-Inducible MxB Protein Inhibits HIV-1 Infection

(2013) Zhenlong Liu et al.   Cell Host & Microbe

Immune Sensing of DNA

(2013) Søren R. Paludan et al.   IMMUNITY

Cytosolic Sensing of Viruses

(2013) Delphine Goubau et al.   IMMUNITY

A Direct and Versatile Assay Measuring Membrane Penetration of Adenovirus in Single Cells

(2013) M. Suomalainen et al.   JOURNAL OF VIROLOGY

Oncolytic Virotherapy and Immunogenic Cancer Cell Death: Sharpening the Sword for Improved Cancer Treatment Strategies

(2013) Samuel T Workenhe et al.   MOLECULAR THERAPY

Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infection

(2013) Caroline Goujon et al.   NATURE

MX2 is an interferon-induced inhibitor of HIV-1 infection

(2013) Melissa Kane et al.   NATURE

Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection

(2013) Gilad Doitsh et al.   NATURE

New viruses for cancer therapy: meeting clinical needs

(2013) Tanner S. Miest et al.   NATURE REVIEWS MICROBIOLOGY

HIV-1 capsid undergoes coupled binding and isomerization by the nuclear pore protein NUP358

(2013) Katsiaryna Bichel et al.   Retrovirology

Nuclear Pore Scaffold Structure Analyzed by Super-Resolution Microscopy and Particle Averaging

(2013) A. Szymborska et al.   SCIENCE

Cellular Self-Defense: How Cell-Autonomous Immunity Protects Against Pathogens

(2013) F. Randow et al.   SCIENCE

IFI16 DNA Sensor Is Required for Death of Lymphoid CD4 T Cells Abortively Infected with HIV

(2013) K. M. Monroe et al.   SCIENCE

Viral Subversion of Nucleocytoplasmic Trafficking

(2013) Melanie L. Yarbrough et al.   TRAFFIC

Virus interactions with endocytic pathways in macrophages and dendritic cells

(2013) Jason Mercer et al.   TRENDS IN MICROBIOLOGY

Innate immune detection of microbial nucleic acids

(2013) Claudia Gürtler et al.   TRENDS IN MICROBIOLOGY

Viruses Challenge Selectivity Barrier of Nuclear Pores

(2013) Aksana Labokha et al.   Viruses-Basel

Uncoating of non-enveloped viruses

(2013) Maarit Suomalainen et al.   Current Opinion in Virology

Nucleoporin NUP153 Phenylalanine-Glycine Motifs Engage a Common Binding Pocket within the HIV-1 Capsid Protein to Mediate Lentiviral Infectivity

(2013) Kenneth A. Matreyek et al.   PLoS Pathogens

Divergent Roles of Autophagy in Virus Infection

(2013) Abhilash Chiramel et al.   Cells

Functional Architecture of the Nuclear Pore Complex

(2012) Einat Grossman et al.   Annual Review of Biophysics

A Virological View of Innate Immune Recognition

(2012) Akiko Iwasaki   Annual Review of Microbiology

Adenovirus signalling in entry

(2012) Nina Wolfrum et al.   CELLULAR MICROBIOLOGY

Recent advances in understanding viral evasion of type I interferon

(2012) Kathryne E. Taylor et al.   IMMUNOLOGY

Oncolytic virotherapy

(2012) Stephen J Russell et al.   NATURE BIOTECHNOLOGY

Intrinsic antiviral immunity

(2012) Nan Yan et al.   NATURE IMMUNOLOGY

Organization of the Influenza Virus Replication Machinery

(2012) A. Moeller et al.   SCIENCE

Species-Specific Inhibition of RIG-I Ubiquitination and IFN Induction by the Influenza A Virus NS1 Protein

(2012) Ricardo Rajsbaum et al.   PLoS Pathogens

DNA-PK is a DNA sensor for IRF-3-dependent innate immunity

(2012) Brian J Ferguson et al.   eLife

Virus strategies for passing the nuclear envelope barrier

(2012) Oren Kobiler et al.   Nucleus

Kinesin-1-Mediated Capsid Disassembly and Disruption of the Nuclear Pore Complex Promote Virus Infection

(2011) Sten Strunze et al.   Cell Host & Microbe

Coupling viruses to dynein and kinesin-1

(2011) Mark P Dodding et al.   EMBO JOURNAL

Pathogen Recognition by the Innate Immune System

(2011) Himanshu Kumar et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Suppression of TLR9 Immunostimulatory Motifs in the Genome of a Gammaherpesvirus

(2011) A. C. Pezda et al.   JOURNAL OF IMMUNOLOGY

Nuclear transport of baculovirus: Revealing the nuclear pore complex passage

(2011) Shelly Au et al.   JOURNAL OF STRUCTURAL BIOLOGY

Adenovirus Core Protein VII Protects the Viral Genome from a DNA Damage Response at Early Times after Infection

(2011) K. A. Karen et al.   JOURNAL OF VIROLOGY

Uncoupling Uncoating of Herpes Simplex Virus Genomes from Their Nuclear Import and Gene Expression

(2011) K. Rode et al.   JOURNAL OF VIROLOGY

Simulations of nuclear pore transport yield mechanistic insights and quantitative predictions

(2011) J. S. Mincer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate immune sensing of DNA viruses

(2011) Vijay A.K. Rathinam et al.   VIROLOGY

Pattern Recognition Receptors and the Innate Immune Response to Viral Infection

(2011) Mikayla R. Thompson et al.   Viruses-Basel

Innate immunity modulation in virus entry

(2011) Mathias Faure et al.   Current Opinion in Virology

HIV-1 Capsid-Cyclophilin Interactions Determine Nuclear Import Pathway, Integration Targeting and Replication Efficiency

(2011) Torsten Schaller et al.   PLoS Pathogens

Virus Entry by Endocytosis

(2010) Jason Mercer et al.   Annual Review of Biochemistry

How viruses access the nucleus

(2010) Sarah Cohen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Flexible Use of Nuclear Import Pathways by HIV-1

(2010) KyeongEun Lee et al.   Cell Host & Microbe

Intracellular Toll-like Receptors

(2010) Amanda L. Blasius et al.   IMMUNITY

Stepwise Loss of Fluorescent Core Protein V from Human Adenovirus during Entry into Cells

(2010) D. Puntener et al.   JOURNAL OF VIROLOGY

Selectivity mechanism of the nuclear pore complex characterized by single cargo tracking

(2010) Alan R. Lowe et al.   NATURE

The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1

(2010) Nan Yan et al.   NATURE IMMUNOLOGY

Structures of influenza A proteins and insights into antiviral drug targets

(2010) Kalyan Das et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal Structure of Human Adenovirus at 3.5 A Resolution

(2010) V. S. Reddy et al.   SCIENCE

Atomic Structure of Human Adenovirus by Cryo-EM Reveals Interactions Among Protein Networks

(2010) H. Liu et al.   SCIENCE

The Nuclear Pore Complex and Nuclear Transport

(2010) S. R. Wente et al.   Cold Spring Harbor Perspectives in Biology

Nucleoporin 153 Arrests the Nuclear Import of Hepatitis B Virus Capsids in the Nuclear Basket

(2010) André Schmitz et al.   PLoS Pathogens

Translocation through the nuclear pore: Kaps pave the way

(2009) Reiner Peters   BIOESSAYS

Age-Dependent Deterioration of Nuclear Pore Complexes Causes a Loss of Nuclear Integrity in Postmitotic Cells

(2009) Maximiliano A. D'Angelo et al.   CELL

RANBP2 is an allosteric activator of the conventional kinesin-1 motor protein, KIF5B, in a minimal cell-free system

(2009) Kyoung-in Cho et al.   EMBO REPORTS

The nuclear pore component Nup358 promotes transportin-dependent nuclear import

(2009) S. Hutten et al.   JOURNAL OF CELL SCIENCE

Structure and Energetics of Encapsidated DNA in Bacteriophage HK97 Studied by Scanning Calorimetry and Cryo-electron Microscopy

(2009) Robert L. Duda et al.   JOURNAL OF MOLECULAR BIOLOGY

Accurate single-day titration of adenovirus vectors based on equivalence of protein VII nuclear dots and infectious particles

(2009) Marcin P. Walkiewicz et al.   JOURNAL OF VIROLOGICAL METHODS

Herpesvirus Capsid Association with the Nuclear Pore Complex and Viral DNA Release Involve the Nucleoporin CAN/Nup214 and the Capsid Protein pUL25

(2009) D. Pasdeloup et al.   JOURNAL OF VIROLOGY

HIV-1 exploits importin 7 to maximize nuclear import of its DNA genome

(2009) Lyubov Zaitseva et al.   Retrovirology

Viruses and autophagy

(2009) Sagar B. Kudchodkar et al.   REVIEWS IN MEDICAL VIROLOGY

DNA-tumor virus entry—From plasma membrane to the nucleus

(2009) Daniel Puntener et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Virus Movements on the Plasma Membrane Support Infection and Transmission between Cells

(2009) Christoph J. Burckhardt et al.   PLoS Pathogens

Transportin-SR2 Imports HIV into the Nucleus

(2008) Frauke Christ et al.   CURRENT BIOLOGY

Autonomy and robustness of translocation through the nuclear pore complex: a single-molecule study

(2008) Thomas Dange et al.   JOURNAL OF CELL BIOLOGY

The UL25 Gene Product of Herpes Simplex Virus Type 1 Is Involved in Uncoating of the Viral Genome

(2008) V. G. Preston et al.   JOURNAL OF VIROLOGY

Proteolytic Cleavage of VP1-2 Is Required for Release of Herpes Simplex Virus 1 DNA into the Nucleus

(2008) V. Jovasevic et al.   JOURNAL OF VIROLOGY

X-ray structure of NS1 from a highly pathogenic H5N1 influenza virus

(2008) Zachary A. Bornholdt et al.   NATURE

Processing of Genome 5′ Termini as a Strategy of Negative-Strand RNA Viruses to Avoid RIG-I-Dependent Interferon Induction

(2008) Matthias Habjan et al.   PLoS One

Single-molecule measurements of importin  /cargo complex dissociation at the nuclear pore

(2008) C. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA