Cellular senescence is associated with reorganization of the microtubule cytoskeleton

The effects of donor age on organ transplants: A review and implications for aging research

(2018) Jose Carlos Dayoub et al.   EXPERIMENTAL GERONTOLOGY

Cellular senescence as a therapeutic target to improve renal transplantation outcome

(2018) Hester van Willigenburg et al.   PHARMACOLOGICAL RESEARCH

Distinct and complementary functions of rho kinase isoforms ROCK1 and ROCK2 in prefrontal cortex structural plasticity

(2018) Kelsey M. Greathouse et al.   Brain Structure & Function

Senescence and aging: Causes, consequences, and therapeutic avenues

(2017) Domhnall McHugh et al.   JOURNAL OF CELL BIOLOGY

Microtubules in 3D cell motility

(2017) Benjamin P. Bouchet et al.   JOURNAL OF CELL SCIENCE

The tubulin code at a glance

(2017) Sudarshan Gadadhar et al.   JOURNAL OF CELL SCIENCE

Treatment-limiting renal tubulopathy in patients treated with tenofovir disoproxil fumarate

(2017) L. Hamzah et al.   JOURNAL OF INFECTION

Molecular mechanisms of renal aging

(2017) Roland Schmitt et al.   KIDNEY INTERNATIONAL

ROCK1 but not ROCK2 contributes to RhoA signaling and NMIIA-mediated contractility at the epithelial zonula adherens

(2017) Rashmi Priya et al.   MOLECULAR BIOLOGY OF THE CELL

Regulation of glomerulotubular balance: flow-activated proximal tubule function

(2017) Tong Wang et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Regulation of microtubule nucleation mediated by γ-tubulin complexes

(2017) Vadym Sulimenko et al.   PROTOPLASMA

LINC complexes and nuclear positioning

(2017) Yin Loon Lee et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Short Chain Fatty Acids in the Colon and Peripheral Tissues: A Focus on Butyrate, Colon Cancer, Obesity and Insulin Resistance

(2017) Sean McNabney et al.   Nutrients

Cellular senescence, senescence-associated secretory phenotype, and chronic kidney disease

(2017) Wen-Juan Wang et al.   Oncotarget

ZBP-89 function in colonic stem cells and during butyrate-induced senescence

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Analysis of the gut microbiome and plasma short-chain fatty acid profiles in a spontaneous mouse model of metabolic syndrome

(2017) Kazuchika Nishitsuji et al.   Scientific Reports

Cellular senescence in the aging and diseased kidney

(2017) F. A. Valentijn et al.   Journal of Cell Communication and Signaling

Small molecule compounds that induce cellular senescence

(2016) Nadezhda V. Petrova et al.   AGING CELL

miR-34a is a common link in both HIV- and antiretroviral therapy-induced vascular aging

(2016) Jiaxin Zhan et al.   Aging-US

The growing landscape of tubulin acetylation: lysine 40 and many more

(2016) K. Sadoul et al.   BIOCHEMICAL JOURNAL

Managing chronic kidney disease in the older adults living with HIV

(2016) Frank A. Post   CURRENT OPINION IN INFECTIOUS DISEASES

The emerging role of the tubulin code: From the tubulin molecule to neuronal function and disease

(2016) Soumyananda Chakraborti et al.   Cytoskeleton

Matrix stiffness exerts biphasic control over monocyte–endothelial adhesion via Rho-mediated ICAM-1 clustering

(2016) Harry A. Scott et al.   Integrative Biology

Renal Aging: Causes and Consequences

(2016) Eoin D. O’Sullivan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Cellular senescence in renal ageing and disease

(2016) Ines Sturmlechner et al.   Nature Reviews Nephrology

Alpha-tubulin enhanced renal tubular cell proliferation and tissue repair but reduced cell death and cell-crystal adhesion

(2016) Juthatip Manissorn et al.   Scientific Reports

The Biology of Proteostasis in Aging and Disease

(2015) Johnathan Labbadia et al.   Annual Review of Biochemistry

Lamins: Nuclear Intermediate Filament Proteins with Fundamental Functions in Nuclear Mechanics and Genome Regulation

(2015) Yosef Gruenbaum et al.   Annual Review of Biochemistry

Expression of basolateral organic anion and cation transporters in experimental cadmium nephrotoxicity in rat kidney

(2015) Marija Ljubojević et al.   ARCHIVES OF TOXICOLOGY

Tubulin acetylation: responsible enzymes, biological functions and human diseases

(2015) Lin Li et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Shaping of interphase chromosomes by the microtubule network

(2015) Yael Maizels et al.   FEBS Journal

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(2015) Amy R. Barker et al.   PROTOPLASMA

Targeting of γ-tubulin complexes to microtubule organizing centers: conservation and divergence

(2015) Tien-chen Lin et al.   TRENDS IN CELL BIOLOGY

Histone deacetylase 6 in health and disease

(2015) Carole Seidel et al.   Epigenomics

The aging kidney revisited: A systematic review

(2014) Davide Bolignano et al.   AGEING RESEARCH REVIEWS

Gold nanoparticles induce nuclear damage in breast cancer cells, which is further amplified by hyperthermia

(2014) Mohamed Kodiha et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Aging and Chronic Kidney Disease

(2014) Kosaku Nitta et al.   KIDNEY & BLOOD PRESSURE RESEARCH

Multimodal Effects of Small Molecule ROCK and LIMK Inhibitors on Mitosis, and Their Implication as Anti-Leukemia Agents

(2014) Yusuke Oku et al.   PLoS One

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Advances in the studies of roles of Rho/Rho-kinase in diseases and the development of its inhibitors

(2013) Ronggui Guan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Inhibition of HDAC6 Deacetylase Activity Increases Its Binding with Microtubules and Suppresses Microtubule Dynamic Instability in MCF-7 Cells

(2013) Jayant Asthana et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct roles for ROCK1 and ROCK2 in the regulation of cell detachment

(2013) Jianjian Shi et al.   Cell Death & Disease

Tight Junction Proteins and Oxidative Stress in Heavy Metals-Induced Nephrotoxicity

(2013) José L. Reyes et al.   Biomed Research International

Distinct Distribution and Localization of Rho-kinase in Mouse Epithelial, Muscle and Neural Tissues

(2012) Michiro Iizuka et al.   CELL STRUCTURE AND FUNCTION

Loss of contraction force in dermal fibroblasts with aging due to decreases in myosin light chain phosphorylation enzymes

(2011) Tsutomu Fujimura et al.   ARCHIVES OF PHARMACAL RESEARCH

Quantitative nucleolar proteomics reveals nuclear re-organization during stress- induced senescence in mouse fibroblast

(2011) Bishnupriya kar et al.   BMC CELL BIOLOGY

Nuclear γ-tubulin associates with nucleoli and interacts with tumor suppressor protein C53

(2011) Barbora Hořejší et al.   JOURNAL OF CELLULAR PHYSIOLOGY

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(2011) M. Kunin et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Optimizing Optical Flow Cytometry for Cell Volume-Based Sorting and Analysis

(2011) Amit Tzur et al.   PLoS One

Age-Related Intimal Stiffening Enhances Endothelial Permeability and Leukocyte Transmigration

(2011) J. Huynh et al.   Science Translational Medicine

Premature Senescence of Vascular Cells Is Induced by HIV Protease Inhibitors

(2010) Chloé Lefèvre et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Review on Pharmacokinetics and Pharmacodynamics and the Aging Kidney

(2010) C. Aymanns et al.   Clinical Journal of the American Society of Nephrology

Chronic kidney disease: a public health priority and harbinger of premature cardiovascular disease

(2010) P. Stenvinkel   JOURNAL OF INTERNAL MEDICINE

Cell Senescence in the Aging Kidney

(2010) H. Yang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Microtubules Regulate Migratory Polarity through Rho/ROCK Signaling in T Cells

(2010) Aya Takesono et al.   PLoS One

Rho-kinase inhibitors as therapeutics: from pan inhibition to isoform selectivity

(2009) C. Hahmann et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

RhoA/ROCK1 signaling regulates stress granule formation and apoptosis

(2009) Nien-Pei Tsai et al.   CELLULAR SIGNALLING

Structural Plasticity in Actin and Tubulin Polymer Dynamics

(2009) H. Y. Kueh et al.   SCIENCE

Oxidative stress mislocalizes and retains transport factor importin-α and nucleoporins Nup153 and Nup88 in nuclei where they generate high molecular mass complexes

(2007) Mohamed Kodiha et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH