Glycolipid iGb3 feedback amplifies innate immune responses via CD1d reverse signaling

Metabolic and Epigenetic Coordination of T Cell and Macrophage Immunity

(2017) Anthony T. Phan et al.   IMMUNITY

The tyrosine kinase Src promotes phosphorylation of the kinase TBK1 to facilitate type I interferon production after viral infection

(2017) Xuelian Li et al.   Science Signaling

The tyrosine kinase Src promotes phosphorylation of the kinase TBK1 to facilitate type I interferon production after viral infection

(2017) Xuelian Li et al.   Science Signaling

Innate Immune Pattern Recognition: A Cell Biological Perspective

(2015) Sky W. Brubaker et al.   Annual Review of Immunology

Immune Regulation of Metabolic Homeostasis in Health and Disease

(2015) Jonathan R. Brestoff et al.   CELL

Metabolic reprogramming in macrophages and dendritic cells in innate immunity

(2015) Beth Kelly et al.   CELL RESEARCH

CD1d-dependent endogenous and exogenous lipid antigen presentation

(2015) Rosanna M McEwen-Smith et al.   CURRENT OPINION IN IMMUNOLOGY

Immunometabolism governs dendritic cell and macrophage function

(2015) Luke A.J. O’Neill et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6

(2015) Qian Zhang et al.   NATURE

Biology of CD1- and MR1-Restricted T Cells

(2014) Mariolina Salio et al.   Annual Review of Immunology

Metabolic Regulation of Immune Responses

(2014) Kirthana Ganeshan et al.   Annual Review of Immunology

Proresolving Lipid Mediators and Mechanisms in the Resolution of Acute Inflammation

(2014) Christopher D. Buckley et al.   IMMUNITY

The Identification of the Endogenous Ligands of Natural Killer T Cells Reveals the Presence of Mammalian α-Linked Glycosylceramides

(2014) Lisa Kain et al.   IMMUNITY

Targeted Prostaglandin E2 Inhibition Enhances Antiviral Immunity through Induction of Type I Interferon and Apoptosis in Macrophages

(2014) François Coulombe et al.   IMMUNITY

Macrophages, Immunity, and Metabolic Disease

(2014) Joanne C. McNelis et al.   IMMUNITY

Role and Regulation of CD1d in Normal and Pathological B Cells

(2014) Mohammed S. Chaudhry et al.   JOURNAL OF IMMUNOLOGY

Protective mucosal immunity mediated by epithelial CD1d and IL-10

(2014) Torsten Olszak et al.   NATURE

Metabolism of stromal and immune cells in health and disease

(2014) Bart Ghesquière et al.   NATURE

The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes

(2014) Rachel J. Perry et al.   NATURE

Sphingolipid metabolites in inflammatory disease

(2014) Michael Maceyka et al.   NATURE

TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation

(2014) Bart Everts et al.   NATURE IMMUNOLOGY

The STAT3-Binding Long Noncoding RNA lnc-DC Controls Human Dendritic Cell Differentiation

(2014) P. Wang et al.   SCIENCE

Protein Tyrosine Phosphatase with Proline-Glutamine-Serine-Threonine-Rich Motifs Negatively Regulates TLR-Triggered Innate Responses by Selectively Inhibiting I B Kinase  /NF- B Activation

(2013) P. Zhang et al.   JOURNAL OF IMMUNOLOGY

Crystal Structure and Mechanism of Activation of TANK-Binding Kinase 1

(2013) Amede Larabi et al.   Cell Reports

The Transcription Factor STAT-1 Couples Macrophage Synthesis of 25-Hydroxycholesterol to the Interferon Antiviral Response

(2012) Mathieu Blanc et al.   IMMUNITY

Constitutive MHC class I molecules negatively regulate TLR-triggered inflammatory responses via the Fps–SHP-2 pathway

(2012) Sheng Xu et al.   NATURE IMMUNOLOGY

Inhibition of Pyk2 blocks lung inflammation and injury in a mouse model of acute lung injury

(2012) Yingli Duan et al.   RESPIRATORY RESEARCH

Intracellular MHC class II molecules promote TLR-triggered innate immune responses by maintaining activation of the kinase Btk

(2011) Xingguang Liu et al.   NATURE IMMUNOLOGY

Lysosomal α-Galactosidase Controls the Generation of Self Lipid Antigens for Natural Killer T Cells

(2010) Alexandre Darmoise et al.   IMMUNITY

A Mouse Macrophage Lipidome

(2010) Edward A. Dennis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pyk2 Is Required for Neutrophil Degranulation and Host Defense Responses to Bacterial Infection

(2010) L. A. Kamen et al.   JOURNAL OF IMMUNOLOGY

Subcellular organelle lipidomics in TLR-4-activated macrophages,

(2010) Alexander Y. Andreyev et al.   JOURNAL OF LIPID RESEARCH

CD1d Expression in Paneth Cells and Rat Exocrine Pancreas Revealed by Novel Monoclonal Antibodies Which Differentially Affect NKT Cell Activation

(2010) Elisa Monzon-Casanova et al.   PLoS One

The evolved functions of CD1 during infection

(2009) Anne Kasmar et al.   CURRENT OPINION IN IMMUNOLOGY

Direct CD1d-Mediated Stimulation of APC IL-12 Production and Protective Immune Response to Virus Infection In Vivo

(2009) Simon C. Yue et al.   JOURNAL OF IMMUNOLOGY

Immunologic Glycosphingolipidomics and NKT Cell Development in Mouse Thymus

(2009) Yunsen Li et al.   JOURNAL OF PROTEOME RESEARCH

Crystal Structures of Mouse CD1d-iGb3 Complex and its Cognate Vα14 T Cell Receptor Suggest a Model for Dual Recognition of Foreign and Self Glycolipids

(2008) Dirk M. Zajonc et al.   JOURNAL OF MOLECULAR BIOLOGY