An alphavirus-based therapeutic cancer vaccine: from design to clinical trial
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Title
An alphavirus-based therapeutic cancer vaccine: from design to clinical trial
Authors
Keywords
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Journal
CANCER IMMUNOLOGY IMMUNOTHERAPY
Volume -, Issue -, Pages -
Publisher
Springer Nature America, Inc
Online
2018-11-21
DOI
10.1007/s00262-018-2276-z
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Note: Only part of the references are listed.- Potent therapeutic efficacy of an alphavirus replicon DNA vaccine expressing human papilloma virus E6 and E7 antigens
- (2018) Stephanie van de Wall et al. OncoImmunology
- HPV vaccines – A review of the first decade
- (2017) Diane M. Harper et al. GYNECOLOGIC ONCOLOGY
- Combination GITR targeting/PD-1 blockade with vaccination drives robust antigen-specific antitumor immunity
- (2017) Daniel O. Villarreal et al. Oncotarget
- Electroporation as a vaccine delivery system and a natural adjuvant to intradermal administration of plasmid DNA in macaques
- (2017) Biliana Todorova et al. Scientific Reports
- Both RIG-I and MDA5 detect alphavirus replication in concentration-dependent mode
- (2016) Ivan Akhrymuk et al. VIROLOGY
- Current therapeutic vaccination and immunotherapy strategies for HPV-related diseases
- (2016) Joseph G. Skeate et al. Human Vaccines & Immunotherapeutics
- Global estimates of human papillomavirus vaccination coverage by region and income level: a pooled analysis
- (2016) Laia Bruni et al. Lancet Global Health
- An HPV-E6/E7 immunotherapy plus PD-1 checkpoint inhibition results in tumor regression and reduction in PD-L1 expression
- (2015) A E Rice et al. CANCER GENE THERAPY
- Antigen design enhances the immunogenicity of Semliki Forest virus-based therapeutic human papillomavirus vaccines
- (2015) P P Ip et al. GENE THERAPY
- Complete Regression of Metastatic Cervical Cancer After Treatment With Human Papillomavirus–Targeted Tumor-Infiltrating T Cells
- (2015) Sanja Stevanović et al. JOURNAL OF CLINICAL ONCOLOGY
- Safety, efficacy, and immunogenicity of VGX-3100, a therapeutic synthetic DNA vaccine targeting human papillomavirus 16 and 18 E6 and E7 proteins for cervical intraepithelial neoplasia 2/3: a randomised, double-blind, placebo-controlled phase 2b trial
- (2015) Cornelia L Trimble et al. LANCET
- A rationally designed combined treatment with an alphavirus-based cancer vaccine, sunitinib and low-dose tumor irradiation completely blocks tumor development
- (2015) Oana Draghiciu et al. OncoImmunology
- Sunitinib depletes myeloid-derived suppressor cells and synergizes with a cancer vaccine to enhance antigen-specific immune responses and tumor eradication
- (2015) Oana Draghiciu et al. OncoImmunology
- Myeloid derived suppressor cells—An overview of combat strategies to increase immunotherapy efficacy
- (2015) Oana Draghiciu et al. OncoImmunology
- HPV-Specific Immunotherapy: Key Role for Immunomodulators
- (2014) Stephanie Wall et al. Anti-Cancer Agents in Medicinal Chemistry
- Self-replicating alphavirus RNA vaccines
- (2014) Karl Ljungberg et al. Expert Review of Vaccines
- Radiation-Induced CXCL16 Release by Breast Cancer Cells Attracts Effector T Cells
- (2014) S. Matsumura et al. JOURNAL OF IMMUNOLOGY
- TG1042 (Adenovirus-interferon-γ) in Primary Cutaneous B-cell Lymphomas: A Phase II Clinical Trial
- (2014) Brigitte Dreno et al. PLoS One
- Therapeutic immunization and local low-dose tumor irradiation, a reinforcing combination
- (2013) Oana Draghiciu et al. INTERNATIONAL JOURNAL OF CANCER
- HPV16 synthetic long peptide (HPV16-SLP) vaccination therapy of patients with advanced or recurrent HPV16-induced gynecological carcinoma, a phase II trial
- (2013) Mariette I E van Poelgeest et al. Journal of Translational Medicine
- Alphavirus-based Vaccines Encoding Nonstructural Proteins of Hepatitis C Virus Induce Robust and Protective T-cell Responses
- (2013) Peng Peng Ip et al. MOLECULAR THERAPY
- Phase I Safety and Immunogenicity Evaluations of an Alphavirus Replicon HIV-1 Subtype CgagVaccine in Healthy HIV-1-Uninfected Adults
- (2012) M. Wecker et al. Clinical and Vaccine Immunology
- Rational Design of DNA Vaccines for the Induction of Human Papillomavirus Type 16 E6- and E7-Specific Cytotoxic T-Cell Responses
- (2012) Koen Oosterhuis et al. HUMAN GENE THERAPY
- Immunization With WT1-derived Peptides by Tattooing Inhibits the Growth of TRAMP-C2 Prostate Tumor in Mice
- (2012) Katarina Babiarova et al. JOURNAL OF IMMUNOTHERAPY
- A phase I dose escalation trial of vaccine replicon particles (VRP) expressing prostate-specific membrane antigen (PSMA) in subjects with prostate cancer
- (2012) Susan F. Slovin et al. VACCINE
- Role of regulatory T-cells in immunization strategies involving a recombinant alphavirus vector system
- (2011) Mateusz Walczak et al. ANTIVIRAL THERAPY
- From Tumor Immunosuppression to Eradication: Targeting Homing and Activity of Immune Effector Cells to Tumors
- (2011) Oana Draghiciu et al. Clinical & Developmental Immunology
- Adenoviral Vector Immunity: Its Implications and Circumvention Strategies
- (2011) Yadvinder S. Ahi et al. CURRENT GENE THERAPY
- Anti-PD-1 synergizes with cyclophosphamide to induce potent anti-tumor vaccine effects through novel mechanisms
- (2011) Mikayel Mkrtichyan et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Role of innate signalling pathways in the immunogenicity of alphaviral replicon-based vaccines
- (2011) Tanja I Näslund et al. Virology Journal
- An alphavirus vector overcomes the presence of neutralizing antibodies and elevated numbers of Tregs to induce immune responses in humans with advanced cancer
- (2010) Michael A. Morse et al. JOURNAL OF CLINICAL INVESTIGATION
- Responses against a Subdominant CD8+ T Cell Epitope Protect against Immunopathology Caused by a Dominant Epitope
- (2010) T. J. Ruckwardt et al. JOURNAL OF IMMUNOLOGY
- Heterologous Prime-Boost Immunizations with a Virosomal and an Alphavirus Replicon Vaccine
- (2010) Mateusz Walczak et al. MOLECULAR PHARMACEUTICS
- Alphavirus vectors for cancer therapy
- (2010) Jose I. Quetglas et al. VIRUS RESEARCH
- Optimization of vaccine responses with an E1, E2b and E3-deleted Ad5 vector circumvents pre-existing anti-vector immunity
- (2009) T Osada et al. CANCER GENE THERAPY
- A structural and functional perspective of alphavirus replication and assembly
- (2009) Joyce Jose et al. Future Microbiology
- Vaccination against HPV-16 Oncoproteins for Vulvar Intraepithelial Neoplasia
- (2009) Gemma G. Kenter et al. NEW ENGLAND JOURNAL OF MEDICINE
- Vaccination with human papillomavirus type 16-derived peptides using a tattoo device
- (2009) Dana Pokorná et al. VACCINE
- Randomized, double-blind, Phase 1 trial of an alphavirus replicon vaccine for cytomegalovirus in CMV seronegative adult volunteers
- (2009) David I. Bernstein et al. VACCINE
- Induction of Tumor-Specific CD4+ and CD8+ T-Cell Immunity in Cervical Cancer Patients by a Human Papillomavirus Type 16 E6 and E7 Long Peptides Vaccine
- (2008) M. J.P. Welters et al. CLINICAL CANCER RESEARCH
- DNA vaccines: developing new strategies to enhance immune responses
- (2008) Shaheed A. Abdulhaqq et al. IMMUNOLOGIC RESEARCH
- An HIV-1 clade C DNA prime, NYVAC boost vaccine regimen induces reliable, polyfunctional, and long-lasting T cell responses
- (2008) Alexandre Harari et al. JOURNAL OF EXPERIMENTAL MEDICINE
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