Improving pregnancy outcomes in humans through studies in sheep

Placental Expression of Glucose Transporter Proteins in Pregnancies Complicated by Gestational and Pregestational Diabetes Mellitus

(2018) Paweł Jan Stanirowski et al.   Canadian Journal of Diabetes

EXTENDing fetal life: postnatal placentae for preterm babies

(2018) Mary Judith Berry   JOURNAL OF PHYSIOLOGY-LONDON

Guinea pig models for translation of the developmental origins of health and disease hypothesis into the clinic

(2018) Janna L. Morrison et al.   JOURNAL OF PHYSIOLOGY-LONDON

The role of miRNA regulation in fetal cardiomyocytes, cardiac maturation and the risk of heart disease in adults

(2018) Mitchell C. Lock et al.   JOURNAL OF PHYSIOLOGY-LONDON

The CRISPR tool kit for genome editing and beyond

(2018) Mazhar Adli   Nature Communications

Mammalian genomic regulatory regions predicted by utilizing human genomics, transcriptomics, and epigenetics data

(2018) Quan H Nguyen et al.   GigaScience

CRISPR/Cas9-mediated loss of FGF5 function increases wool staple length in sheep

(2017) Wen-Rong Li et al.   FEBS Journal

Delayed intranasal infusion of human amnion epithelial cells improves white matter maturation after asphyxia in preterm fetal sheep

(2017) Lotte G van den Heuij et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Antenatal dexamethasone before asphyxia promotes cystic neural injury in preterm fetal sheep by inducing hyperglycemia

(2017) Christopher A Lear et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Akt signaling as a mediator of cardiac adaptation to low birth weight

(2017) Kimberley C W Wang et al.   JOURNAL OF ENDOCRINOLOGY

RNAseq profiling of primary microglia and astrocyte cultures in near-term ovine fetus: A glial in vivo-in vitro multi-hit paradigm in large mammalian brain

(2017) M. Cortes et al.   JOURNAL OF NEUROSCIENCE METHODS

Surfactant phospholipid composition of gastric aspirate samples differs between male and female very preterm infants

(2017) Foula Sozo et al.   PEDIATRIC RESEARCH

Mid-Childhood Bone Mass After Exposure to Repeat Doses of Antenatal Glucocorticoids: A Randomized Trial

(2017) Christopher J.D. McKinlay et al.   PEDIATRICS

Uptake and release of amino acids in the fetal-placental unit in human pregnancies

(2017) Maia Blomhoff Holm et al.   PLoS One

Gene expression allelic imbalance in ovine brown adipose tissue impacts energy homeostasis

(2017) Shila Ghazanfar et al.   PLoS One

Effect of proline rich 15-deficiency on trophoblast viability and survival

(2017) Katherine C. Gates et al.   PLoS One

Reconstruction and evolutionary history of eutherian chromosomes

(2017) Jaebum Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CRISPR is knocking on barn door

(2017) I Lamas-Toranzo et al.   REPRODUCTION IN DOMESTIC ANIMALS

Disruption of the sheep BMPR-IB gene by CRISPR/Cas9 in in vitro -produced embryos

(2017) Xuemei Zhang et al.   THERIOGENOLOGY

Sheep Placenta Cotyledons: A Noninvasive Source of Ovine Mesenchymal Stem Cells

(2017) Iris Ribitsch et al.   TISSUE ENGINEERING PART C-METHODS

An extra-uterine system to physiologically support the extreme premature lamb

(2017) Emily A. Partridge et al.   Nature Communications

Alteration of sheep coat color pattern by disruption of ASIP gene via CRISPR Cas9

(2017) Xuemei Zhang et al.   Scientific Reports

The effects of preterm birth and its antecedents on the cardiovascular system

(2016) Jonathan G. Bensley et al.   ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA

Outside-in? Acute fetal systemic inflammation in very preterm chronically catheterized sheep fetuses is not driven by cells in the fetal blood

(2016) Matthew W. Kemp et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Maternofetal pharmacokinetics and fetal lung responses in chronically catheterized sheep receiving constant, low-dose infusions of betamethasone phosphate

(2016) Matthew W. Kemp et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Impact of maternal undernutrition around the time of conception on factors regulating hepatic lipid metabolism and microRNAs in singleton and twin fetuses

(2016) Shervi Lie et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Development of ovine chorionic somatomammotropin hormone-deficient pregnancies

(2016) Callie M. Baker et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

FoetalUreaplasma parvumbacteraemia as a function of gestation-dependent complement insufficiency: Evidence from a sheep model of pregnancy

(2016) Matthew W. Kemp et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Biallelicβ-carotene oxygenase 2knockout results in yellow fat in sheep via CRISPR/Cas9

(2016) Y. Niu et al.   ANIMAL GENETICS

Neonatal milk supplementation in lambs has persistent effects on growth and metabolic function that differ by sex and gestational age

(2016) Mary J. Berry et al.   BRITISH JOURNAL OF NUTRITION

Novel Approaches to Neonatal Resuscitation and the Impact on Birth Asphyxia

(2016) Arjan B. Te Pas et al.   CLINICS IN PERINATOLOGY

Empowering Translational Research in Fetal Growth Restriction: Sheep and Swine Animal Models

(2016) Antonio Gonzalez-Bulnes et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Maternal Administration of Sildenafil Citrate Alters Fetal and Placental Growth and Fetal–Placental Vascular Resistance in the Growth-Restricted Ovine FetusNovelty and Significance

(2016) Charlotte Oyston et al.   HYPERTENSION

In utero Programming of Allergic Susceptibility

(2016) Jessica A. Grieger et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

S0118 A hierarchy of epigenetic changes in the developmental transition from brown to white perirenal adipose tissue

(2016) T. Vuocolo et al.   JOURNAL OF ANIMAL SCIENCE

Betamethasone-exposed preterm birth does not impair insulin action in adult sheep

(2016) R De Matteo et al.   JOURNAL OF ENDOCRINOLOGY

Effects of preterm birth and ventilation on glomerular capillary growth in the neonatal lamb kidney

(2016) Megan R. Sutherland et al.   JOURNAL OF HYPERTENSION

Neuroinflammation and structural injury of the fetal ovine brain following intra-amniotic Candida albicans exposure

(2016) Daan R. M. G. Ophelders et al.   Journal of Neuroinflammation

Fetalin vivocontinuous cardiovascular function during chronic hypoxia

(2016) B. J. Allison et al.   JOURNAL OF PHYSIOLOGY-LONDON

The fetal brain sparing response to hypoxia: physiological mechanisms

(2016) Dino A. Giussani   JOURNAL OF PHYSIOLOGY-LONDON

Mid-Childhood Outcomes of Repeat Antenatal Corticosteroids: A Randomized Controlled Trial

(2016) C. A. Crowther et al.   PEDIATRICS

Programming the brain: Common outcomes and gaps in knowledge from animal studies of IUGR

(2016) Damien S. Hunter et al.   PHYSIOLOGY & BEHAVIOR

Intrauterine Candida albicans Infection Causes Systemic Fetal Candidiasis With Progressive Cardiac Dysfunction in a Sheep Model of Early Pregnancy

(2016) Sarah J. Stock et al.   Reproductive Sciences

Experimentally Induced Preterm Birth in Sheep Following a Clinical Course of Antenatal Betamethasone: Effects on Growth and Long-Term Survival

(2016) Vivian B. Nguyen et al.   Reproductive Sciences

Limited fetal metabolism of rosiglitazone: Elimination via the maternal compartment in the pregnant ewe

(2016) Maryam Bazargan et al.   REPRODUCTIVE TOXICOLOGY

Noninvasive high-intensity focused ultrasound treatment of twin-twin transfusion syndrome: A preliminary in vivo study

(2016) Caroline J. Shaw et al.   Science Translational Medicine

Stress-induced decrease of uterine blood flow in sheep is mediated by alpha 1-adrenergic receptors

(2016) Michelle Dreiling et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

Antenatal drug consumption: the burden of self-medication in a developing world setting

(2016) Abiodun Idowu Adanikin et al.   TROPICAL DOCTOR

A review of fundamental principles for animal models of DOHaD research: an Australian perspective

(2016) H. Dickinson et al.   Journal of Developmental Origins of Health and Disease

Intra-amniotic Candida albicans infection induces mucosal injury and inflammation in the ovine fetal intestine

(2016) Maria Nikiforou et al.   Scientific Reports

Placental Nutrient Transport and Intrauterine Growth Restriction

(2016) Francesca Gaccioli et al.   Frontiers in Physiology

Induction of Human iPSC-Derived Cardiomyocyte Proliferation Revealed by Combinatorial Screening in High Density Microbioreactor Arrays

(2016) Drew M. Titmarsh et al.   Scientific Reports

Cardiometabolic Risk Factors in Young Adults Who Were Born Preterm

(2015) M. Sipola-Leppanen et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Depletion of polymorphonuclear leukocytes has no effect on preterm delivery in a mouse model of Escherichia coli-induced labor

(2015) Yana Filipovich et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Effect of placental restriction and neonatal exendin-4 treatment on postnatal growth, adult body composition, and in vivo glucose metabolism in the sheep

(2015) Hong Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Utility of large-animal models of BPD: chronically ventilated preterm lambs

(2015) Kurt H. Albertine   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Acute exercise increases insulin sensitivity in adult sheep: a new preclinical model

(2015) Glenn K. McConell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

IGF-2R-Gαq signaling and cardiac hypertrophy in the low-birth-weight lamb

(2015) Kimberley C. W. Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Impact of chronic hypoxemia on blood flow to the brain, heart, and adrenal gland in the late-gestation IUGR sheep fetus

(2015) Rajan Poudel et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Biological Roles of Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1), HSD11B2, and Glucocorticoid Receptor (NR3C1) in Sheep Conceptus Elongation1

(2015) Kelsey Brooks et al.   BIOLOGY OF REPRODUCTION

Differential effect of intrauterine growth restriction on childhood neurodevelopment: a systematic review

(2015) E Murray et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Regulation of microRNA during cardiomyocyte maturation in sheep

(2015) Janna L Morrison et al.   BMC GENOMICS

Enhancer Evolution across 20 Mammalian Species

(2015) Diego Villar et al.   CELL

Dynamics of Cell Generation and Turnover in the Human Heart

(2015) Olaf Bergmann et al.   CELL

Percutaneous Fetal Cardiac Catheterization Technique for Stenting the Foramen Ovale in a Midgestation Lamb Model

(2015) A. Edwards et al.   Circulation-Cardiovascular Interventions

Principles and standards for reporting animal experiments inThe Journal of PhysiologyandExperimental Physiology

(2015) David Grundy   EXPERIMENTAL PHYSIOLOGY

Timing of cardiomyocyte growth, maturation, and attrition in perinatal sheep

(2015) Sonnet S. Jonker et al.   FASEB JOURNAL

Using 2 Assessment Methods May Better Describe Dietary Supplement Intakes in the United States

(2015) Holly L Nicastro et al.   JOURNAL OF NUTRITION

Cardiovascular function in term fetal sheep conceived, gestated and studied in the hypobaric hypoxia of the Andeanaltiplano

(2015) Emilio A. Herrera et al.   JOURNAL OF PHYSIOLOGY-LONDON

Intra-amniotic pharmacological blockade of inflammatory signalling pathways in an ovine chorioamnionitis model

(2015) D. J. Ireland et al.   MOLECULAR HUMAN REPRODUCTION

Fluconazole treatment of intrauterine Candida albicans infection in fetal sheep

(2015) Gunlawadee Maneenil et al.   PEDIATRIC RESEARCH

Cardiovascular Risk Factors in Children After Repeat Doses of Antenatal Glucocorticoids: An RCT

(2015) C. J. D. McKinlay et al.   PEDIATRICS

Preterm Birth and Poor Fetal Growth as Risk Factors of Attention-Deficit/Hyperactivity Disorder

(2015) M. Sucksdorff et al.   PEDIATRICS

Patterns of gene expression in the sheep heart during the perinatal period revealed by transcriptomic modeling

(2015) Elaine M. Richards et al.   PHYSIOLOGICAL GENOMICS

Placental and fetal growth restriction, size at birth and neonatal growth alter cognitive function and behaviour in sheep in an age- and sex-specific manner

(2015) Damien S. Hunter et al.   PHYSIOLOGY & BEHAVIOR

Do I turn left or right? Effects of sex, age, experience and exit route on maze test performance in sheep

(2015) Damien S. Hunter et al.   PHYSIOLOGY & BEHAVIOR

Efficient Generation of Myostatin Knock-Out Sheep Using CRISPR/Cas9 Technology and Microinjection into Zygotes

(2015) M. Crispo et al.   PLoS One

Folate and folic acid in the periconceptional period: recommendations from official health organizations in thirty-six countries worldwide and WHO

(2015) Sandra Gomes et al.   PUBLIC HEALTH NUTRITION

Coordinated international action to accelerate genome-to-phenome with FAANG, the Functional Annotation of Animal Genomes project

(2015) Leif Andersson et al.   GENOME BIOLOGY

Instrumentation of Near-term Fetal Sheep for Multivariate Chronic Non-anesthetized Recordings

(2015) Patrick Burns et al.   Jove-Journal of Visualized Experiments

Repeated maternal intramuscular or intraamniotic erythromycin incompletely resolves intrauterine Ureaplasma parvum infection in a sheep model of pregnancy

(2014) Matthew W. Kemp et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Impact of embryo number and maternal undernutrition around the time of conception on insulin signaling and gluconeogenic factors and microRNAs in the liver of fetal sheep

(2014) Shervi Lie et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Chorioamnionitis-induced fetal gut injury is mediated by direct gut exposure of inflammatory mediators or by lung inflammation

(2014) Tim G. A. M. Wolfs et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Genomic architecture of histone 3 lysine 27 trimethylation during late ovine skeletal muscle development

(2014) K. Byrne et al.   ANIMAL GENETICS

Maternal Intravenous Treatment with either Azithromycin or Solithromycin Clears Ureaplasma parvum from the Amniotic Fluid in an Ovine Model of Intrauterine Infection

(2014) Yuichiro Miura et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Transcriptomics of the late gestation ovine fetal brain: modeling the co-expression of immune marker genes

(2014) Maria B Rabaglino et al.   BMC GENOMICS

The Oxygen-Rich Postnatal Environment Induces Cardiomyocyte Cell-Cycle Arrest through DNA Damage Response

(2014) Bao N. Puente et al.   CELL

Rapidly alternating photoperiods disrupt central and peripheral rhythmicity and decrease plasma glucose, but do not affect glucose tolerance or insulin secretion in sheep

(2014) Tamara J. Varcoe et al.   EXPERIMENTAL PHYSIOLOGY

Decidual Neutrophil Infiltration Is Not Required for Preterm Birth in a Mouse Model of Infection-Induced Preterm Labor

(2014) S. F. Rinaldi et al.   JOURNAL OF IMMUNOLOGY

Melatonin improves cerebrovascular function and decreases oxidative stress in chronically hypoxic lambs

(2014) Emilio A. Herrera et al.   JOURNAL OF PINEAL RESEARCH

Antenatal antioxidant treatment with melatonin to decrease newborn neurodevelopmental deficits and brain injury caused by fetal growth restriction

(2014) Suzanne L. Miller et al.   JOURNAL OF PINEAL RESEARCH

Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts

(2014) James J. H. Chong et al.   NATURE

Defining the role of common variation in the genomic and biological architecture of adult human height

(2014) Andrew R Wood et al.   NATURE GENETICS

Genomicus update 2015: KaryoView and MatrixView provide a genome-wide perspective to multispecies comparative genomics

(2014) Alexandra Louis et al.   NUCLEIC ACIDS RESEARCH

Ventilation-Induced Increases in EGFR Ligand mRNA Are Not Altered by Intra-Amniotic LPS or Ureaplasma in Preterm Lambs

(2014) Noah H. Hillman et al.   PLoS One

Early Detection of Ventilation-Induced Brain Injury Using Magnetic Resonance Spectroscopy and Diffusion Tensor Imaging: An In Vivo Study in Preterm Lambs

(2014) Béatrice Skiöld et al.   PLoS One

A percutaneous fetal cardiac catheterization technique for pulmonary valvuloplasty and valvulotomy in a mid-gestation lamb model

(2014) Andrew Edwards et al.   PRENATAL DIAGNOSIS

Defining functional DNA elements in the human genome

(2014) M. Kellis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The sheep genome illuminates biology of the rumen and lipid metabolism

(2014) Y. Jiang et al.   SCIENCE

A Comparison of the Histological Structure of the Placenta in Experimental Animals

(2014) Satoshi Furukawa et al.   Journal of Toxicologic Pathology

Patterns of psychotropic medicine use in pregnancy in the United States from 2006 to 2011 among women with private insurance

(2014) Gillian E Hanley et al.   BMC Pregnancy and Childbirth

Optimal Management of the Critically Ill: Anaesthesia, Monitoring, Data Capture, and Point-of-Care Technological Practices in Ovine Models of Critical Care

(2014) Saul Chemonges et al.   Biomed Research International

Chronic Hypoxemia in Late Gestation Decreases Cardiomyocyte Number but Does Not Change Expression of Hypoxia‐Responsive Genes

(2014) Kimberley J. Botting et al.   Journal of the American Heart Association

Prenatal Programming of Pulmonary Hypertension Induced by Chronic Hypoxia or Ductal Ligation in Sheep

(2014) Demosthenes G. Papamatheakis et al.   Pulmonary Circulation

Antenatal corticosteroid exposure at term increases adult adiposity: an experimental study in sheep

(2013) Mary J. Berry et al.   ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA

The developmental transition of ovine adipose tissue through early life

(2013) M. Pope et al.   Acta Physiologica

Impact of embryo number and periconceptional undernutrition on factors regulating adipogenesis, lipogenesis, and metabolism in adipose tissuein the sheep fetus

(2013) Shervi Lie et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Prenatal exposure to selective serotonin reuptake inhibitors and childhood overweight at 7 years of age

(2013) Luke E. Grzeskowiak et al.   ANNALS OF EPIDEMIOLOGY

Ureaplasma parvum Undergoes Selection In Utero Resulting in Genetically Diverse Isolates Colonizing the Chorioamnion of Fetal Sheep1

(2013) Samantha J. Dando et al.   BIOLOGY OF REPRODUCTION

Periconceptional Undernutrition Programs Changes in Insulin-Signaling Molecules and MicroRNAs in Skeletal Muscle in Singleton and Twin Fetal Sheep1

(2013) Shervi Lie et al.   BIOLOGY OF REPRODUCTION

Regulation of fetal lung development in response to maternal overnutrition

(2013) Mitchell Lock et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Mechanisms of Melatonin-Induced Protection in the Brain of Late Gestation Fetal Sheep in Response to Hypoxia

(2013) Tamara Yawno et al.   DEVELOPMENTAL NEUROSCIENCE

Effects of Antenatal Synthetic Glucocorticoid on Glucocorticoid Receptor Binding, DNA Methylation, and Genome-Wide mRNA Levels in the Fetal Male Hippocampus

(2013) Ariann Crudo et al.   ENDOCRINOLOGY

Blood pressure regulation VIII: resistance vessel tone and implications for a pro-atherogenic conduit artery endothelial cell phenotype

(2013) Jaume Padilla et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Alteration of cardiac glucose metabolism in association to low birth weight: Experimental evidence in lambs with left ventricular hypertrophy

(2013) Kimberley C.W. Wang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Umbilical uptakes and transplacental concentration ratios of amino acids in severe fetal growth restriction

(2013) Timothy R.H. Regnault et al.   PEDIATRIC RESEARCH

Characterisation of the Maternal Response to Chronic Phase Shifts during Gestation in the Rat: Implications for Fetal Metabolic Programming

(2013) Tamara J. Varcoe et al.   PLoS One

Selective Exposure of the Fetal Lung and Skin/Amnion (but Not Gastro-Intestinal Tract) to LPS Elicits Acute Systemic Inflammation in Fetal Sheep

(2013) Matthew W. Kemp et al.   PLoS One

Preterm Birth Has Sex-Specific Effects on Autonomic Modulation of Heart Rate Variability in Adult Sheep

(2013) Mary Berry et al.   PLoS One

Dietary restriction in the periconceptional period in normal-weight or obese ewes results in increased abundance of angiotensin-converting enzyme (ACE) and angiotensin type 1 receptor (AT1R) in the absence of changes in ACE or AT1R methylation in the adrenal of the offspring

(2013) Song Zhang et al.   REPRODUCTION

Australasian randomised trial to evaluate the role of maternal intramuscular dexamethasone versus betamethasone prior to preterm birth to increase survival free of childhood neurosensory disability (A*STEROID): study protocol

(2013) Caroline A Crowther et al.   BMC Pregnancy and Childbirth

Prolonged infusion of amino acids increases leucine oxidation in fetal sheep

(2012) Anne M. Maliszewski et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Sex differences in cardiorespiratory transition and surfactant composition following preterm birth in sheep

(2012) Noreen Ishak et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Preterm Birth and Psychiatric Disorders in Young Adult Life

(2012) Chiara Nosarti et al.   ARCHIVES OF GENERAL PSYCHIATRY

Hypothermia for Neonatal Hypoxic Ischemic Encephalopathy

(2012) Mohamed A. Tagin et al.   ARCHIVES OF PEDIATRICS & ADOLESCENT MEDICINE

IGF-2R-Mediated Signaling Results in Hypertrophy of Cultured Cardiomyocytes from Fetal Sheep1

(2012) Kimberley C.W. Wang et al.   BIOLOGY OF REPRODUCTION

Detection of gene expression changes at chromosomal rearrangement breakpoints in evolution

(2012) Adriana Muñoz et al.   BMC BIOINFORMATICS

Early origins of heart disease: Low birth weight and the role of the insulin-like growth factor system in cardiac hypertrophy

(2012) Kimberley CW Wang et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

The development of autonomic cardiovascular control is altered by preterm birth

(2012) Stephanie R. Yiallourou et al.   EARLY HUMAN DEVELOPMENT

Placental Restriction Reduces Insulin Sensitivity and Expression of Insulin Signaling and Glucose Transporter Genes in Skeletal Muscle, But Not Liver, in Young Sheep

(2012) Miles J. De Blasio et al.   ENDOCRINOLOGY

Fetal cardiac function after labetalol or pindolol for maternal hypertension in a sheep model of increased placental vascular resistance

(2012) Tiina Erkinaro et al.   European Journal of Obstetrics & Gynecology and Reproductive Biology

Lipid metabolism, adipocyte depot physiology and utilization of meat animals as experimental models for metabolic research

(2012) Michael V. Dodson et al.   International Journal of Biological Sciences

microRNA expression profiling of the developing mouse heart

(2012) LI CAO et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

National, regional, and worldwide estimates of preterm birth rates in the year 2010 with time trends since 1990 for selected countries: a systematic analysis and implications

(2012) Hannah Blencowe et al.   LANCET

Antenatal ureaplasma infection impairs development of the fetal ovine gut in an IL-1-dependent manner

(2012) T G A M Wolfs et al.   Mucosal Immunology

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

The Instrumented Fetal Sheep as a Model of Cerebral White Matter Injury in the Premature Infant

(2012) Stephen A. Back et al.   Neurotherapeutics

Quantitative Allele-Specific Expression and DNA Methylation Analysis of H19, IGF2 and IGF2R in the Human Placenta across Gestation Reveals H19 Imprinting Plasticity

(2012) Sam Buckberry et al.   PLoS One

Functional roles of fructose

(2012) J. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adipose tissue development during early life: novel insights into energy balance from small and large mammals

(2012) Michael E. Symonds et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Growth in the neonatal period after repeat courses of antenatal corticosteroids: data from the ACTORDS randomised trial

(2011) Malcolm Battin et al.   Archives of Disease in Childhood-Fetal and Neonatal Edition

Genetic architecture of gene expression in ovine skeletal muscle

(2011) Lisette JA Kogelman et al.   BMC GENOMICS

White Matter Protection with Insulin-Like Growth Factor 1 and Hypothermia Is Not Additive after Severe Reversible Cerebral Ischemia in Term Fetal Sheep

(2011) S. George et al.   DEVELOPMENTAL NEUROSCIENCE

Baroreflex control of renal sympathetic nerve activity and heart rate in near-term fetal sheep

(2011) Lindsea C. Booth et al.   EXPERIMENTAL PHYSIOLOGY

Simple HPLC method for determination of rosiglitazone in sheep plasma and amniotic fluid and its application in a pregnant sheep model

(2011) Maryam Bazargan et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Maternal dexamethasone and EEG hyperactivity in preterm fetal sheep

(2011) Joanne O. Davidson et al.   JOURNAL OF PHYSIOLOGY-LONDON

Fetal growth restriction and the programming of heart growth and cardiac insulin-like growth factor 2 expression in the lamb

(2011) Kimberley C. W. Wang et al.   JOURNAL OF PHYSIOLOGY-LONDON

Statin treatment depresses the fetal defence to acute hypoxia via increasing nitric oxide bioavailability

(2011) Andrew D. Kane et al.   JOURNAL OF PHYSIOLOGY-LONDON

Fetal and postnatal pulmonary circulation in the Alto Andino

(2011) A.J. Llanos et al.   PLACENTA

Upregulation of growth signaling and nutrient transporters in cotyledons of early to mid-gestational nutrient restricted ewes☆

(2011) Y. Ma et al.   PLACENTA

Executive Decision-Making in the Domestic Sheep

(2011) A. Jennifer Morton et al.   PLoS One

Ontogenesis of phase I hepatic drug metabolic enzymes in sheep

(2011) Manoja Pretheeban et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

Interleukin-1 in Lipopolysaccharide Induced Chorioamnionitis in the Fetal Sheep

(2011) Clare A. Berry et al.   Reproductive Sciences

Preterm Cerebellar Growth Impairment After Postnatal Exposure to Glucocorticoids

(2011) E. W. Y. Tam et al.   Science Translational Medicine

A Small-Molecule Smoothened Agonist Prevents Glucocorticoid-Induced Neonatal Cerebellar Injury

(2011) V. M. Heine et al.   Science Translational Medicine

Intrauterine infection and preterm labor

(2011) Varkha Agrawal et al.   Seminars in Fetal & Neonatal Medicine

The Early Origins of Cardiovascular Health and Disease: Who, When, and How

(2011) Christian Rueda-Clausen et al.   SEMINARS IN REPRODUCTIVE MEDICINE

Maternal obesity markedly increases placental fatty acid transporter expression and fetal blood triglycerides at midgestation in the ewe

(2010) Mei J. Zhu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Effect of Maternal Protein Restriction During Pregnancy and Lactation on the Number of Cardiomyocytes in the Postproliferative Weanling Rat Heart

(2010) Kyungjoon Lim et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Isoflurane-induced Neuroapoptosis in the Neonatal Rhesus Macaque Brain

(2010) Ansgar M. Brambrink et al.   ANESTHESIOLOGY

Carbohydrate quantitative digestion and absorption in ruminants: from feed starch and fibre to nutrients available for tissues

(2010) P. Nozière et al.   Animal

Development of the hypothalamus-pituitary-adrenal axis of the equine fetus: A comparative review

(2010) C. E. WOOD et al.   EQUINE VETERINARY JOURNAL

Periconceptional undernutrition in normal and overweight ewes leads to increased adrenal growth and epigenetic changes in adrenal IGF2/H19 gene in offspring

(2010) Song Zhang et al.   FASEB JOURNAL

Prenatal hypoxia independent of undernutrition promotes molecular markers of insulin resistance in adult offspring

(2010) E. J. Camm et al.   FASEB JOURNAL

Melatonin and vitamin C increase umbilical blood flow via nitric oxide-dependent mechanisms

(2010) Avnesh S. Thakor et al.   JOURNAL OF PINEAL RESEARCH

Improving bioscience research reporting: ARRIVE-ing at a solution

(2010) C Kilkenny et al.   LABORATORY ANIMALS

Sex bias in trials and treatment must end

(2010) Alison M. Kim et al.   NATURE

Effects of sex, litter size and periconceptional ewe nutrition on offspring behavioural and physiological response to isolation

(2010) C.E. Hernandez et al.   PHYSIOLOGY & BEHAVIOR

Review: Placental Programming of Postnatal Diabetes and Impaired Insulin Action after IUGR

(2010) K.L. Gatford et al.   PLACENTA

Induced Preterm Birth in Sheep: A Suitable Model for Studying the Developmental Effects of Moderately Preterm Birth

(2010) Robert De Matteo et al.   Reproductive Sciences

Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research

(2010) Carol Kilkenny et al.   PLOS BIOLOGY

Betamethasone dose and formulation for induced lung maturation in fetal sheep

(2009) Alan H. Jobe et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Modulation of fetal inflammatory response on exposure to lipopolysaccharide by chorioamnion, lung, or gut in sheep

(2009) Boris W. Kramer et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Resveratrol, an activator of SIRT1, upregulates sarcoplasmic calcium ATPase and improves cardiac function in diabetic cardiomyopathy

(2009) M. Sulaiman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

IL-8 signaling does not mediate intra-amniotic LPS-induced inflammation and maturation in preterm fetal lamb lung

(2009) Suhas G. Kallapur et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Effects of litter size, sex and periconceptional ewe nutrition on side preference and cognitive flexibility in the offspring

(2009) Carlos E. Hernandez et al.   BEHAVIOURAL BRAIN RESEARCH

The Involvement of Proline-Rich 15 in Early Conceptus Development in Sheep1

(2009) Scott H. Purcell et al.   BIOLOGY OF REPRODUCTION

Reconstruction of metabolic pathways for the cattle genome

(2009) Seongwon Seo et al.   BMC Systems Biology

Lung function in developing lambs: is it affected by preterm birth?

(2009) Robert De Matteo et al.   JOURNAL OF APPLIED PHYSIOLOGY

Prenatal nicotine-exposure alters fetal autonomic activity and medullary neurotransmitter receptors: implications for sudden infant death syndrome

(2009) Jhodie R. Duncan et al.   JOURNAL OF APPLIED PHYSIOLOGY

The transition from fetal growth restriction to accelerated postnatal growth: a potential role for insulin signalling in skeletal muscle

(2009) B. S. Muhlhausler et al.   JOURNAL OF PHYSIOLOGY-LONDON

Undernutrition Before Mating in Ewes Impairs the Development of Insulin Resistance During Pregnancy

(2009) Anne L. Jaquiery et al.   OBSTETRICS AND GYNECOLOGY

Airway Injury From Initiating Ventilation in Preterm Sheep

(2009) Noah H Hillman et al.   PEDIATRIC RESEARCH

Differing Prevalence and Diversity of Bacterial Species in Fetal Membranes from Very Preterm and Term Labor

(2009) Hannah E. Jones et al.   PLoS One

The Genome Sequence of Taurine Cattle: A Window to Ruminant Biology and Evolution

(2009) et al.   SCIENCE

Experimental amniotic fluid infection in sheep: Effects of Ureaplasma parvum serovars 3 and 6 on preterm or term fetal sheep

(2008) Timothy J.M. Moss et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

The transplacental transport of essential amino acids in uncomplicated human pregnancies

(2008) Henry L. Galan et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

The effects of sildenafil citrate (Viagra) on uterine blood flow and well being in the intrauterine growth-restricted fetus

(2008) Suzanne L. Miller et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Arrested oligodendrocyte lineage maturation in chronic perinatal white matter injury

(2008) Kristen N. Segovia et al.   ANNALS OF NEUROLOGY

SHEEP MODELS OF INTRAUTERINE GROWTH RESTRICTION: FETAL ADAPTATIONS AND CONSEQUENCES

(2008) Janna L Morrison   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Cerebrovascular Injury in Premature Infants: Current Understanding and Challenges for Future Prevention

(2008) Adré J. du Plessis   CLINICS IN PERINATOLOGY

Impaired β-Cell Function and Inadequate Compensatory Increases in β-Cell Mass after Intrauterine Growth Restriction in Sheep

(2008) Kathryn L. Gatford et al.   ENDOCRINOLOGY

Prescription drug use during pregnancy: a population-based study in Regione Emilia-Romagna, Italy

(2008) Joshua J. Gagne et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Expression of glucocorticoid receptor, mineralocorticoid receptor, and 11β-hydroxysteroid dehydrogenase 1 and 2 in the fetal and postnatal ovine hippocampus: ontogeny and effects of prenatal glucocorticoid exposure

(2008) Deborah M Sloboda et al.   JOURNAL OF ENDOCRINOLOGY

Multiple courses of antenatal corticosteroids

(2008) John P Newnham et al.   LANCET

Epidemiology and causes of preterm birth

(2008) Robert L Goldenberg et al.   LANCET

Glucose Replacement to Euglycemia Causes Hypoxia, Acidosis, and Decreased Insulin Secretion in Fetal Sheep With Intrauterine Growth Restriction

(2008) Paul J Rozance et al.   PEDIATRIC RESEARCH

Uteroplacental insufficiency alters the mammary gland response to lactogenic hormonesin vitro

(2008) Rachael O'Dowd et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

Effects of Betamethasone Treatment on Central Myelination in Fetal Sheep: An Electron Microscopical Study

(2007) C. Raschke et al.   ANATOMIA HISTOLOGIA EMBRYOLOGIA

Influence of maternal undernutrition and overfeeding on cardiac ciliary neurotrophic factor receptor and ventricular size in fetal sheep

(2007) Feng Dong et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY