Article
Rheumatology
Anthony James Ocon, George Reed, Dimitrios A. Pappas, Jeffrey R. Curtis, Joel M. Kremer
Summary: The study found that initiating glucocorticoids in steroid-naive RA patients is associated with an increased risk of cardiovascular events, especially at daily doses of >= 5mg, cumulative doses exceeding 1100mg, and durations longer than 81 days. No increased risk was found at lower doses or shorter durations.
ANNALS OF THE RHEUMATIC DISEASES
(2021)
Review
Cardiac & Cardiovascular Systems
Dashuai Wang, Yang Lu, Manda Sun, Xiaofan Huang, Xinling Du, Zhouyang Jiao, Fuqiang Sun, Fei Xie
Summary: This article summarized the incidence, risk factors, and interventions for postoperative pneumonia (POP) after cardiovascular surgery, emphasizing the importance of prevention and treatment of POP.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Review
Biochemistry & Molecular Biology
Mirjam Mocnik, Natasa Marcun Varda
Summary: Obesity poses an increasing burden on cardiovascular health in children, highlighting the importance of prevention. Hormonal changes and vascular dysfunction associated with obesity can lead to chronic diseases and increased cardiovascular risk. Various preventive strategies are being implemented to reduce the cardiovascular burden in children.
Article
Hematology
Steve Raoul Noumegni, Vincent Mansourati, Cecile Tromeur, Raphael Le Mao, Clement Hoffmann, Emmanuelle Le Moigne, Bahaa Nasr, Jean-Christophe Gentric, Marie Guegan, Elise Poulhazan, Luc Bressollette, Karine Lacut, Francis Couturaud, Romain Didier
Summary: This study found that risk factors for CVDT after VTE in patients include some traditional cardiovascular risk factors as well as other risk factors related to characteristics of VTE and patients' comorbidities. Specific factors such as age, cancer-associated VTE, unprovoked VTE, tobacco use history, hypertension, chronic heart failure, etc., were associated with the risk of CVDT.
THROMBOSIS AND HAEMOSTASIS
(2022)
Review
Cardiac & Cardiovascular Systems
Yuan-Yuan Zeng, Min Zhang, Syeun Ko, Feng Chen
Summary: Kawasaki disease, first described in Japan 50 years ago, is a worldwide multisystem disease characterized by acute self-limited inflammation that can lead to coronary artery lesions in children, making it one of the common causes of acquired heart disease among children in developed countries. Patients with Kawasaki disease may develop severe complications such as coronary aneurysms, with concerns focusing on endothelial damage and early onset of atherosclerosis.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Multidisciplinary Sciences
Abdulrahman Altheaby, Nuha Alajlan, Mohammed F. Shaheen, Ghaleb Abosamah, Basma Ghallab, Basayl Aldawsari, Awatif Rashidi, Mohammed Gafar, Ziad Arabi
Summary: The study investigated the incidence of weight gain postrenal transplantation and identified potential risk factors, showing that patients with lower dialysis duration, a living kidney donor, and baseline obesity were more likely to gain weight. Close monitoring of weight changes in kidney transplant patients is necessary, and further research is needed to determine risk factors and appropriate interventions.
Article
Surgery
Sameh Hany Emile, Michael R. Freund, Nir Horesh, Zoe Garoufalia, Rachel Gefen, Emanuela Silva-Alvarenga, Steven D. Wexner
Summary: Longer operation time and previous open ileocolic resection are risk factors for complications and conversion to open surgery in repeat ileocolic resection for Crohn's disease.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Anesthesiology
Kumiko Tanabe, Takuma Ishihara, Yoshimi Nakamura, Noritaka Yoshimura, Shinobu Yamaguchi, Reiko Suetsugu, Hiroki Lida
Summary: The study aimed to measure changes in glucose levels after a single-dose dexamethasone injection with nerve blockade using a continuous glucose monitoring system in non-diabetes mellitus patients, and investigate potential risk factors for hyperglycemia.
Article
Health Care Sciences & Services
Alina-Costina Luca, Alexandrina-Stefania Curpan, Elena Emanuela Braha, Elena Tarca, Alin-Constantin Iordache, Florin-Alexandru Luca, Heidrun Adumitrachioaiei
Summary: Childhood obesity is a global health issue with significant cardiovascular impact. Hypertension, hypertrophic cardiomyopathy, atherosclerosis risk, and hypercholesterolemia are among the main cardiovascular conditions associated with obesity. Early detection and prevention of obesity and its complications are crucial to prevent cardiovascular dysfunction in adulthood.
Review
Psychology, Multidisciplinary
Anem Iftikhar, Mohammad Islam, Simon Shepherd, Sarah Jones, Ian Ellis
Summary: Lifestyle factors, including alcohol consumption and smoking, play a significant role in the development of head and neck cancers. Promoting healthy lifestyle choices is crucial for improving health and preventing diseases. Stress is known to contribute to the adoption of unhealthy habits such as alcohol and smoking. Understanding the impact of stress on lifestyle choices and exploring the underlying mechanisms can facilitate the development of prevention measures.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Psychiatry
Daphne J. Korczak, Kristin Cleverley, Catherine S. Birken, Tony Pignatiello, Farid H. Mahmud, Brian W. McCrindle
Summary: The study found that cardiovascular disease risk factors are prevalent among children and adolescents with Major Depressive Disorder, with over half of participants having at least two risk factors. Routine screening for cardiovascular risk factors may be warranted among youth with MDD, regardless of BMI, to prevent future cardiovascular disease.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Medicine, General & Internal
Esteban Sanchez-Toscano, Jesus Dominguez-Riscart, Laura Larran-Escandon, Isabel Mateo-Gavira, Manuel Aguilar-Diosdado
Summary: In the first year of hormonal treatment, transgender individuals experience changes in their metabolic profiles, including early alterations in lipid and carbohydrate metabolism, slight increases in blood pressure, and weight gain. Therefore, lifestyle interventions are necessary from the beginning of hormone therapy.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Frederick K. Ho, Stuart R. Gray, Paul Welsh, Jason M. R. Gill, Naveed Sattar, Jill P. Pell, Carlos Celis-Morales
Summary: This study explores the differences in cardiovascular disease (CVD) risk and associated factors among South Asian, Black, and White individuals. The results suggest that adiposity is an important risk factor for CVD regardless of ethnicity. Targeting interventions based on different risk profiles may be the most effective approach to address ethnic inequalities in CVD incidence.
Article
Cardiac & Cardiovascular Systems
Jennifer J. Stuart, Lauren J. Tanz, Eric B. Rimm, Donna Spiegelman, Stacey A. Missmer, Kenneth J. Mukamal, Kathryn M. Rexrode, Janet W. Rich-Edwards
Summary: This study aimed to evaluate the association between hypertensive disorders of pregnancy (HDP) and long-term cardiovascular disease (CVD) and identify the proportion mediated by established CVD risk factors. The results showed that women with HDP during their first pregnancy had a higher risk of CVD, which was mainly mediated by established CVD risk factors.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Endocrinology & Metabolism
Carolina C. V. Silva, Vincent W. V. Jaddoe, Chalana M. Sol, Hanan El Marroun, Maria-Pilar Martinez-Moral, Kurunthachalam Kannan, Leonardo Trasande, Susana Santos
Summary: The study found that higher levels of DNOP metabolites at 6 years old were associated with an increased risk of overweight and adverse cardiovascular profile at both 6 and 10 years. On the other hand, higher total bisphenols and bisphenol A concentrations were linked to a decrease in BMI from 6 to 10 years.
Article
Pediatrics
Elizabeth Anne Oliphant, Christopher J. D. McKinlay, David McNamara, Alana Cavadino, Jane M. Alsweiler
Summary: The study aimed to establish the most effective and best tolerated dose of caffeine citrate for preventing intermittent hypoxaemia (IH) in late preterm infants. The results showed that caffeine reduces the rate of IH in late preterm infants, with a dose of 20 mg/kg/day being the most effective.
ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION
(2023)
Article
Nursing
Billie F. Bradford, Robin S. Cronin, Jane Warland, Anna Akselsson, Ingela Radestad, Alexander E. P. Heazell, Christopher J. D. McKinlay, Tomasina Stacey, John M. D. Thompson, Lesley M. E. McCowan
Summary: Presentations for decreased fetal movements are common and associated with adverse pregnancy outcomes. Inconsistent practice and lack of evidence-based information about fetal movements are issues. Recent research suggests that comprehensive information tailored to individual needs may empower women to assess fetal wellbeing.
Review
Pediatrics
Shalini Ramachandran, Marlies Bruckner, Myra H. Wyckoff, Georg M. Schmolzer
Summary: This study found a limited number of clinical studies on neonatal cardiopulmonary resuscitation, with the majority of evidence coming from manikin and animal studies. The findings either supported or did not provide sufficient evidence to change previous recommendations.
ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION
(2023)
Article
Clinical Neurology
Darren W. T. Dai, Nike Franke, Christopher J. D. McKinlay, Trecia A. Wouldes, Gavin T. L. Brown, Rajesh Shah, Samson Nivins, Jane E. Harding
Summary: The aim of the study was to investigate the relationship between neonatal hypoglycemia and specific aspects of executive function and behavior in mid-childhood. Participants were assessed using performance-based and questionnaire-based measures, and it was found that children who experienced hypoglycemia had a higher risk of metacognition difficulties, peer problems, and conduct problems. Both performance-based and questionnaire-based executive functions were associated with behavior problems.
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
(2023)
Article
Pediatrics
Sophie L. St Clair, Darren W. T. Dai, Deborah L. Harris, Gregory D. Gamble, Christopher J. D. McKinlay, Samson Nivins, Rajesh K. Shah, Benjamin Thompson, Jane E. Harding
Summary: In the treatment of neonatal hypoglycaemia, dextrose gel is safe and effective, but at 9-10 years old, children in the dextrose gel group had slightly lower visual perception abilities compared to the placebo group.
Article
Pediatrics
Eleanor Kennedy, Samson Nivins, Benjamin Thompson, Christopher J. D. McKinlay, Jane Harding
Summary: This study investigated the association between neonatal hypoglycemia and caudate volume, as well as neurodevelopmental outcomes. The results showed that neonatal hypoglycemia is associated with smaller caudate volume but does not contribute to clinically relevant neurodevelopmental deficits. Smaller caudate volume is associated with emotional and behavioral difficulties in mid-childhood and poorer prosocial behavior.
PEDIATRIC RESEARCH
(2023)
Article
Pediatrics
Elizabeth E. Foglia, Peter Davis, Ruth Guinsburg, Vishal G. Kapadia, Helen Liley, Mario M. Ruediger, Georg L. Schmoelzer, Marya H. Strand, Myra Wyckoff, Jonathan M. Wyllie, Gary Weiner
Summary: Clinical research on neonatal resuscitation has been accelerated, but the lack of standardized definitions or reporting guidelines is a major limitation. To address this, a working group developed the first Utstein-style reporting guideline, focusing on the resuscitation of newborns immediately after birth. The guideline is expected to standardize data definitions, facilitate meta-analyses, and improve treatment recommendations.
Article
Nursing
Julena Ardern, Brooke Hayward, Alain C. C. Vandal, Margot Martin-Babin, Christin Coomarasamy, Chris McKinlay
Summary: The aim of this study was to investigate the effects of using admission lanyards on nurse confidence, care coordination, and infant health outcomes during neonatal emergency admissions. The results showed that the use of lanyards improved clarity of roles and responsibilities, communication, and task delegation, leading to better admission flow, team leadership, accountability, and improved nurse confidence. Additionally, there was a significant reduction in time to stabilization for infants in the intervention group.
JOURNAL OF PERINATAL & NEONATAL NURSING
(2023)
Article
Medicine, Research & Experimental
Brett J. Manley, C. Omar F. Kamlin, Susan Donath, Li Huang, Pita Birch, Jeanie L. Y. Cheong, Peter A. Dargaville, Jennifer A. Dawson, Lex W. Doyle, Susan E. Jacobs, Rodney Wilson, Peter G. Davis, Christopher J. D. McKinlay
Summary: This study aims to explore the method of administering budesonide mixed with surfactant through endotracheal tube or thin catheter in order to reduce the incidence of bronchopulmonary dysplasia in extremely preterm infants, and to improve their neurodevelopmental and respiratory outcomes.
Article
Psychology, Developmental
Andrew E. Silva, Jane Harding, Arijit W. Chakraborty, Darren W. D. Dai, Greg Gamble, Christopher J. D. McKinlay, Samson Nivins, Rajesh Shah, Benjamin Thompson
Summary: The study found widespread associations between dorsal stream functions and autistic traits, with sex differences in the associations between visual processing and neurodevelopment.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2023)
Article
Obstetrics & Gynecology
Michelle R. Wise, John M. D. Thompson, Malcolm Battin, Jenny McDougall, Jessica Wilson, Joy Marriott, Michael Stitely, Lynn Sadler
Summary: This study compared the effectiveness of outpatient balloon catheter induction with inpatient vaginal prostaglandin E2 induction. It was found that outpatient balloon catheter induction did not reduce the cesarean delivery rate compared to inpatient vaginal prostaglandin E2 induction, and it also did not increase the rate of adverse events.
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2023)
Article
Multidisciplinary Sciences
Trusha J. Purohit, Don Laing, Christopher J. D. Mckinlay, Jane M. Alsweiler, Sara M. Hanning
Summary: The present study developed and validated a efficient extraction method for quantifying diazoxide from neonatal plasma. The method showed good linearity and accuracy, and demonstrated the stability of diazoxide in plasma.
Article
Ophthalmology
Mukhit Kulmaganbetov, Myra Leung, Jane M. Alsweiler, Joanna Black, Frank H. Bloomfield, Greg D. Gamble, Jane E. Harding, Yannan Jiang, Tanya Poppe, Anna C. Tottman, Trecia A. Wouldes, Benjamin Thompson
Summary: This study aimed to assess the effect of increased protein intake on ophthalmic and visual development in school-age children born very preterm. The results showed that there were subtle and complex associations between early neonatal nutrition and visual development at school age.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2023)
Article
Pediatrics
Nike Franke, Trecia Ann Wouldes, Gavin Thomas Lumsden Brown, Kim Ward, Jenny Rogers, Jane E. Harding
Summary: This study explores the views of young adults on their participation in medical research during childhood, specifically focusing on the acceptability of consent and their priorities regarding health, development, and well-being as potential trial outcomes. The findings indicate that participants were comfortable with their parents giving consent on their behalf, but highlighted the challenges of obtaining autonomous child assent. They generally expressed satisfaction with the outcomes investigated in the follow-up studies, while also suggesting additional outcomes of interest such as mental health and learning disabilities.
ARCHIVES OF DISEASE IN CHILDHOOD
(2023)