Piezo1 mediates angiogenesis through activation of MT1-MMP signaling

Src-dependent phosphorylation of caveolin-1 Tyr-14 promotes swelling and release of caveolae

(2016) Adriana M. Zimnicka et al.   MOLECULAR BIOLOGY OF THE CELL

Removal of the mechanoprotective influence of the cytoskeleton reveals PIEZO1 is gated by bilayer tension

(2016) Charles D. Cox et al.   Nature Communications

Quantitative phospho-proteomics reveals the Plasmodium merozoite triggers pre-invasion host kinase modification of the red cell cytoskeleton

(2016) Elizabeth S. Zuccala et al.   Scientific Reports

Fluid shear stress promotes proprotein convertase-dependent activation of MT1-MMP

(2015) Hojin Kang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Architecture of the mammalian mechanosensitive Piezo1 channel

(2015) Jingpeng Ge et al.   NATURE

Piezo1 regulates mechanotransductive release of ATP from human RBCs

(2015) Eyup Cinar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Piezo1 ion channel pore properties are dictated by C-terminal region

(2015) Bertrand Coste et al.   Nature Communications

Piezo1 forms mechanosensitive ion channels in the human MCF-7 breast cancer cell line

(2015) Chouyang Li et al.   Scientific Reports

Chemical activation of the mechanotransduction channel Piezo1

(2015) Ruhma Syeda et al.   eLife

Piezo1 links mechanical forces to red blood cell volume

(2015) Stuart M Cahalan et al.   eLife

Mechanical sensitivity of Piezo1 ion channels can be tuned by cellular membrane tension

(2015) Amanda H Lewis et al.   eLife

The Role of Mechanical Forces in Tumor Growth and Therapy

(2014) Rakesh K. Jain et al.   Annual Review of Biomedical Engineering

Piezo1 Is as a Novel Trefoil Factor Family 1 Binding Protein that Promotes Gastric Cancer Cell Mobility In Vitro

(2014) Xiao-Ning Yang et al.   DIGESTIVE DISEASES AND SCIENCES

Piezo1 integration of vascular architecture with physiological force

(2014) Jing Li et al.   NATURE

Stretch-activated ion channel Piezo1 directs lineage choice in human neural stem cells

(2014) Medha M. Pathak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Engineered kinase activation reveals unique morphodynamic phenotypes and associated trafficking for Src family isoforms

(2014) P.-H. Chu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Piezo1, a mechanically activated ion channel, is required for vascular development in mice

(2014) S. S. Ranade et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective deletion of the endothelial sphingosine-1-phosphate 1 receptor exacerbates kidney ischemia–reperfusion injury

(2013) Ahrom Ham et al.   KIDNEY INTERNATIONAL

Xerocytosis is caused by mutations that alter the kinetics of the mechanosensitive channel PIEZO1

(2013) C. Bae et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Calpain-mediated vimentin cleavage occurs upstream of MT1-MMP membrane translocation to facilitate endothelial sprout initiation

(2012) Hyeong-Il Kwak et al.   ANGIOGENESIS

Synergistic Regulation of Angiogenic Sprouting by Biochemical Factors and Wall Shear Stress

(2011) Roland Kaunas et al.   Cellular and Molecular Bioengineering

Fluid Shear Stress and Sphingosine 1-Phosphate Activate Calpain to Promote Membrane Type 1 Matrix Metalloproteinase (MT1-MMP) Membrane Translocation and Endothelial Invasion into Three-dimensional Collagen Matrices

(2011) Hojin Kang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of Sphingosine 1-Phosphate Receptor 2 Protects against Renal Ischemia-Reperfusion Injury

(2011) S. Won Park et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives

(2011) Jeng-Jiann Chiu et al.   PHYSIOLOGICAL REVIEWS

Angiogenesis

(2011) D. R. Senger et al.   Cold Spring Harbor Perspectives in Biology

Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

(2010) Kai Kessenbrock et al.   CELL

Manganese superoxide dismutase expression in endothelial progenitor cells accelerates wound healing in diabetic mice

(2010) Eric J. Marrotte et al.   JOURNAL OF CLINICAL INVESTIGATION

The Effects of Hemodynamic Force on Embryonic Development

(2010) JAMES C. CULVER et al.   MICROCIRCULATION

VEGF and endothelial guidance in angiogenic sprouting

(2010) Holger Gerhardt   Organogenesis

Endothelial cell lumen and vascular guidance tunnel formation requires MT1-MMP-dependent proteolysis in 3-dimensional collagen matrices

(2009) A. N. Stratman et al.   BLOOD

Fluid shear stress modulates endothelial cell invasion into three-dimensional collagen matrices

(2008) Hojin Kang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Interstitial Fluid Flow Intensity Modulates Endothelial Sprouting in Restricted Src-Activated Cell Clusters During Capillary Morphogenesis

(2008) Rodrigo Hernández Vera et al.   TISSUE ENGINEERING PART A