Chromosome instability and carcinogenesis: Insights from murine models of human pancreatic cancer associated with BRCA2 inactivation

Mouse models for studying angiogenesis and lymphangiogenesis in cancer

(2013) Lauri Eklund et al.   Molecular Oncology

Genetically engineered mouse models of pancreatic adenocarcinoma

(2013) Carmen Guerra et al.   Molecular Oncology

High grade prostatic intraepithelial neoplasia does not display loss of heterozygosity at the mutation locus inBRCA2mutation carriers with aggressive prostate cancer

(2012) Amber Willems-Jones et al.   BJU INTERNATIONAL

Genome-Wide Somatic Copy Number Alterations in Low-Grade PanINs and IPMNs from Individuals with a Family History of Pancreatic Cancer

(2012) S.-M. Hong et al.   CLINICAL CANCER RESEARCH

BRCA2 Fine-Tunes the Spindle Assembly Checkpoint through Reinforcement of BubR1 Acetylation

(2012) Eunhee Choi et al.   DEVELOPMENTAL CELL

BRCA2 Localization to the Midbody by Filamin A Regulates CEP55 Signaling and Completion of Cytokinesis

(2012) Gourish Mondal et al.   DEVELOPMENTAL CELL

Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer

(2012) Michael A Jacobetz et al.   GUT

Gamma secretase inhibition promotes hypoxic necrosis in mouse pancreatic ductal adenocarcinoma

(2012) Natalie Cook et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

(2012) Andrew V. Biankin et al.   NATURE

nab -Paclitaxel Potentiates Gemcitabine Activity by Reducing Cytidine Deaminase Levels in a Mouse Model of Pancreatic Cancer

(2012) Kristopher K. Frese et al.   Cancer Discovery

Inactivation ofBrca2cooperates withTrp53R172Hto induce invasive pancreatic ductal adenocarcinomas in mice

(2011) Georg Feldmann et al.   CANCER BIOLOGY & THERAPY

Double-Strand Break Repair-Independent Role for BRCA2 in Blocking Stalled Replication Fork Degradation by MRE11

(2011) Katharina Schlacher et al.   CELL

A genetic screen identifies BRCA2 and PALB2 as key regulators of G2 checkpoint maintenance

(2011) Tobias Menzel et al.   EMBO REPORTS

Tetraploidy in BRCA2 breast tumours

(2011) Asta Bjork Jonsdottir et al.   EUROPEAN JOURNAL OF CANCER

Inactivation of Brca2 Promotes Trp53-Associated but Inhibits KrasG12D-Dependent Pancreatic Cancer Development in Mice

(2011) Matthew Rowley et al.   GASTROENTEROLOGY

Integrated genomic analyses of ovarian carcinoma

(2011) D. Bell et al.   NATURE

Germline Brca2 Heterozygosity Promotes KrasG12D -Driven Carcinogenesis in a Murine Model of Familial Pancreatic Cancer

(2010) Ferdinandos Skoulidis et al.   CANCER CELL

brca2 in zebrafish ovarian development, spermatogenesis, and tumorigenesis

(2010) H. R. Shive et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Carboxyl Terminus of Brca2 Links the Disassembly of Rad51 Complexes to Mitotic Entry

(2009) Nabieh Ayoub et al.   CURRENT BIOLOGY

Inhibition of γ-Secretase Activity Inhibits Tumor Progression in a Mouse Model of Pancreatic Ductal Adenocarcinoma

(2009) Ruben Plentz et al.   GASTROENTEROLOGY

Exomic Sequencing Identifies PALB2 as a Pancreatic Cancer Susceptibility Gene

(2009) S. Jones et al.   SCIENCE

Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer

(2009) K. P. Olive et al.   SCIENCE

Pancreatic Cancer

(2008) Anirban Maitra et al.   Annual Review of Pathology-Mechanisms of Disease

Linking the Cellular Functions of BRCA Genes to Cancer Pathogenesis and Treatment

(2008) Ashok R. Venkitaraman   Annual Review of Pathology-Mechanisms of Disease

Loss of Heterozygosity at the BRCA2 Locus Detected by Multiplex Ligation-Dependent Probe Amplification is Common in Prostate Cancers from Men with a Germline BRCA2 Mutation

(2008) A. J. Willems et al.   CLINICAL CANCER RESEARCH