Identification of Polycomb Group Protein EZH2-Mediated DNA Mismatch Repair Gene MSH2 in Human Uterine Fibroids

Microsatellite instability: an update

(2015) Hiroyuki Yamamoto et al.   ARCHIVES OF TOXICOLOGY

MicroRNA-144 suppresses tumorigenesis and tumor progression of astrocytoma by targeting EZH2

(2015) Lvbiao Lin et al.   HUMAN PATHOLOGY

MiR-137 inhibits proliferation and angiogenesis of human glioblastoma cells by targeting EZH2

(2015) Jie Sun et al.   JOURNAL OF NEURO-ONCOLOGY

The Mechanism and Function of Epigenetics in Uterine Leiomyoma Development

(2015) Qiwei Yang et al.   Reproductive Sciences

Mismatch repair gene expression in gastroesophageal cancers

(2015) Amelia Dracea et al.   Turkish Journal of Gastroenterology

IGF-1 signaling in neonatal hypoxia-induced pulmonary hypertension: Role of epigenetic regulation

(2015) Qiwei Yang et al.   VASCULAR PHARMACOLOGY

microRNA-217 inhibits tumor progression and metastasis by downregulating EZH2 and predicts favorable prognosis in gastric cancer

(2015) Dong-liang Chen et al.   Oncotarget

MED12 mutation frequency in unselected sporadic uterine leiomyomas

(2014) Hanna-Riikka Heinonen et al.   FERTILITY AND STERILITY

Colon and Endometrial Cancers With Mismatch Repair Deficiency Can Arise From Somatic, Rather Than Germline, Mutations

(2014) Sigurdis Haraldsdottir et al.   GASTROENTEROLOGY

Immunohistochemical Survey of Mismatch Repair Protein Expression in Uterine Sarcomas and Carcinosarcomas

(2014) Lien N. Hoang et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY

Targeting histone methyltransferase EZH2 as cancer treatment

(2014) Y. Kondo   JOURNAL OF BIOCHEMISTRY

MED12 and HMGA2 mutations: two independent genetic events in uterine leiomyoma and leiomyosarcoma

(2014) Elizabeth Bertsch et al.   MODERN PATHOLOGY

EZH2 Represses Target Genes through H3K27-Dependent and H3K27-Independent Mechanisms in Hepatocellular Carcinoma

(2014) Shu-Bin Gao et al.   MOLECULAR CANCER RESEARCH

HDAC6 Deacetylates and Ubiquitinates MSH2 to Maintain Proper Levels of MutSα

(2014) Mu Zhang et al.   MOLECULAR CELL

Novel MED12 gene somatic mutations in women from the Southern United States with symptomatic uterine fibroids

(2014) Sunil K. Halder et al.   MOLECULAR GENETICS AND GENOMICS

PRC2 is recurrently inactivated through EED or SUZ12 loss in malignant peripheral nerve sheath tumors

(2014) William Lee et al.   NATURE GENETICS

Deficiency of MSH2 expression is associated with clear cell renal cell carcinoma

(2014) KOO HAN YOO et al.   Oncology Letters

Complex MSH2 and MSH6 mutations in hypermutated microsatellite unstable advanced prostate cancer

(2014) Colin C. Pritchard et al.   Nature Communications

Regulation and Role of EZH2 in Cancer

(2014) Hirohito Yamaguchi et al.   Cancer Research and Treatment

DNA Mismatch Repair and Oxidative DNA Damage: Implications for Cancer Biology and Treatment

(2014) Gemma Bridge et al.   Cancers

EZH2: biology, disease and structure-based drug discovery

(2013) Jin-zhi Tan et al.   ACTA PHARMACOLOGICA SINICA

Role of histone deacetylases in regulation of phenotype of ovine newborn pulmonary arterial smooth muscle cells

(2013) Q. Yang et al.   CELL PROLIFERATION

Towards Gene Therapy of Postoperative Adhesions: Fiber and Transcriptional Modifications Enhance Adenovirus Targeting towards Human Adhesion Cells

(2013) S. Nair et al.   GYNECOLOGIC AND OBSTETRIC INVESTIGATION

Targeting adenoviral vectors for enhanced gene therapy of uterine leiomyomas

(2013) S. Nair et al.   HUMAN REPRODUCTION

Vitamin D3 inhibits expression and activities of matrix metalloproteinase-2 and -9 in human uterine fibroid cells

(2013) S. K. Halder et al.   HUMAN REPRODUCTION

Uterine Fibroids

(2013) Serdar E. Bulun   NEW ENGLAND JOURNAL OF MEDICINE

Epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A inhibits the growth of cholangiocarcinoma cells

(2013) SHIGEKI NAKAGAWA et al.   ONCOLOGY REPORTS

Mutation status of the mediator complex subunit 12 (MED12) in uterine leiomyomas and concurrent/metachronous multifocal peritoneal smooth muscle nodules (leiomyomatosis peritonealis disseminata)

(2013) Ralf J. Rieker et al.   PATHOLOGY

EZH2 Regulates the Expression of p16 in the Nasopharyngeal Cancer Cells

(2013) Jing Zhong et al.   TECHNOLOGY IN CANCER RESEARCH & TREATMENT

EZH2 Methyltransferase and H3K27 Methylation in Breast Cancer

(2012) Kyung Hyun Yoo et al.   International Journal of Biological Sciences

Epigenetic therapy with 3-deazaneplanocin A, an inhibitor of the histone methyltransferase EZH2, inhibits growth of non-small cell lung cancer cells

(2012) Junko Kikuchi et al.   LUNG CANCER

Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes

(2012) Karolina Holm et al.   Molecular Oncology

PRC2/EED-EZH2 Complex Is Up-Regulated in Breast Cancer Lymph Node Metastasis Compared to Primary Tumor and Correlates with Tumor Proliferation In Situ

(2012) Hongxiang Yu et al.   PLoS One

Association of Rad51 polymorphism with DNA repair in BRCA1 mutation carriers and sporadic breast cancer risk

(2011) Luisel J Ricks-Santi et al.   BMC CANCER

The role of EZH2 in tumour progression

(2011) C-J Chang et al.   BRITISH JOURNAL OF CANCER

EZH2 Promotes Expansion of Breast Tumor Initiating Cells through Activation of RAF1-β-Catenin Signaling

(2011) Chun-Ju Chang et al.   CANCER CELL

EZH2 Promotes Malignant Phenotypes and Is a Predictor of Oral Cancer Development in Patients with Oral Leukoplakia

(2011) W. Cao et al.   Cancer Prevention Research

Polycomb protein EZH2 regulates cancer cell fate decision in response to DNA damage

(2011) Z Wu et al.   CELL DEATH AND DIFFERENTIATION

Aberrations of EZH2 in Cancer

(2011) A. Chase et al.   CLINICAL CANCER RESEARCH

Pharmacologic disruption of Polycomb Repressive Complex 2 inhibits tumorigenicity and tumor progression in prostate cancer

(2011) Francesco Crea et al.   Molecular Cancer

EZH2-Dependent Suppression of a Cellular Senescence Phenotype in Melanoma Cells by Inhibition of p21/CDKN1A Expression

(2011) T. Fan et al.   MOLECULAR CANCER RESEARCH

Context-Specific Regulation of NF-κB Target Gene Expression by EZH2 in Breast Cancers

(2011) Shuet Theng Lee et al.   MOLECULAR CELL

Is genetic polymorphism of ER-α, CYP1A1, and CYP1B1 a risk factor for uterine leiomyoma?

(2010) Gehan A. El-Shennawy et al.   ARCHIVES OF GYNECOLOGY AND OBSTETRICS

Epigenetic alterations differ in phenotypically distinct human neuroblastoma cell lines

(2010) Qiwei Yang et al.   BMC CANCER

Polycomb Group Proteins: Multi-Faceted Regulators of Somatic Stem Cells and Cancer

(2010) Martin Sauvageau et al.   Cell Stem Cell

Missing mismatch repair: a key to T cell immortality

(2010) Antoaneta Belcheva et al.   LEUKEMIA & LYMPHOMA

Microsatellite instability in colorectal cancer—the stable evidence

(2010) Eduardo Vilar et al.   Nature Reviews Clinical Oncology

Role of MUTYH and MSH2 in the Control of Oxidative DNA Damage, Genetic Instability, and Tumorigenesis

(2009) M. T. Russo et al.   CANCER RESEARCH

Biochemical mechanisms of gene regulation by polycomb group protein complexes

(2009) Jürg Müller et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Genetic polymorphisms of DNA repair gene XRCC1 and risk of uterine leiomyoma

(2009) Yang Yang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Roles of the EZH2 histone methyltransferase in cancer epigenetics

(2008) Jeffrey A. Simon et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation

(2008) Yutaka Kondo et al.   NATURE GENETICS

Polycomb Repressive Complex 2 (PRC2) Restricts Hematopoietic Stem Cell Activity

(2008) Ian J Majewski et al.   PLOS BIOLOGY