Galectin-3 is a regulator of metaflammation in adipose tissue and pancreatic islets

Galectin-3 Is a Negative Regulator of Lipopolysaccharide-Mediated Inflammation

(2014) Y. Li et al.   JOURNAL OF IMMUNOLOGY

Regulation of Alternative Macrophage Activation by Galectin-3

(2014) A. C. MacKinnon et al.   JOURNAL OF IMMUNOLOGY

Galectin-3 Deficiency Reduces the Severity of Experimental Autoimmune Encephalomyelitis

(2014) H.-R. Jiang et al.   JOURNAL OF IMMUNOLOGY

Galectin-3 Deficiency Accelerates High-Fat Diet-Induced Obesity and Amplifies Inflammation in Adipose Tissue and Pancreatic Islets

(2013) N. N. Pejnovic et al.   DIABETES

Inhibition of galectin-3 reduces atherosclerosis in apolipoprotein E-deficient mice

(2013) A. C. MacKinnon et al.   GLYCOBIOLOGY

Adipose tissue-specific modulation of galectin expression in lean and obese mice: Evidence for regulatory function

(2013) Davina H. Rhodes et al.   Obesity

Increased Adiposity, Dysregulated Glucose Metabolism and Systemic Inflammation in Galectin-3 KO Mice

(2013) Jingbo Pang et al.   PLoS One

TLR-induced NF-κB activation regulates NLRP3 expression in murine macrophages

(2012) Yu Qiao et al.   FEBS LETTERS

Direct control of hepatic glucose production by interleukin-13 in mice

(2012) Kristopher J. Stanya et al.   JOURNAL OF CLINICAL INVESTIGATION

Brown adipose tissue regulates glucose homeostasis and insulin sensitivity

(2012) Kristin I. Stanford et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of Galectin-3 in Classical and Alternative Macrophage Activation in the Liver following Acetaminophen Intoxication

(2012) A.-C. D. Dragomir et al.   JOURNAL OF IMMUNOLOGY

The cellular and signaling networks linking the immune system and metabolism in disease

(2012) Olivia Osborn et al.   NATURE MEDICINE

Inflammatory Mechanisms in Obesity

(2011) Margaret F. Gregor et al.   Annual Review of Immunology

Deletion of galectin-3 in the host attenuates metastasis of murine melanoma by modulating tumor adhesion and NK cell activity

(2011) Gordana Radosavljevic et al.   CLINICAL & EXPERIMENTAL METASTASIS

Galectin-3 deficiency prevents concanavalin A-induced hepatitis in mice

(2011) Vladislav Volarevic et al.   HEPATOLOGY

Inflammatory links between obesity and metabolic disease

(2011) Carey N. Lumeng et al.   JOURNAL OF CLINICAL INVESTIGATION

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

(2011) Bolormaa Vandanmagsar et al.   NATURE MEDICINE

Transcriptional analysis of the endothelial response to diabetes reveals a role for galectin-3

(2011) April L. Darrow et al.   PHYSIOLOGICAL GENOMICS

Inflammasome is a central player in the induction of obesity and insulin resistance

(2011) R. Stienstra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Galectins: regulators of acute and chronic inflammation

(2010) Fu-Tong Liu et al.   Annals of the New York Academy of Sciences

JNK1 and IKKβ: molecular links between obesity and metabolic dysfunction

(2010) Giovanni Solinas et al.   FASEB JOURNAL

Galectin-3 ablation protects mice from diet-induced NASH: A major scavenging role for galectin-3 in liver

(2010) Carla Iacobini et al.   JOURNAL OF HEPATOLOGY

T-Cell Recruitment and Th1 Polarization in Adipose Tissue During Diet-Induced Obesity in C57BL/6 Mice

(2010) Katherine J. Strissel et al.   Obesity

Induction of regulatory T cells decreases adipose inflammation and alleviates insulin resistance in ob/ob mice

(2010) Y. Ilan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The NLRP3 Inflammasome: A Sensor for Metabolic Danger?

(2010) K. Schroder et al.   SCIENCE

Accelerated Lipid-Induced Atherogenesis in Galectin-3-Deficient Mice

(2009) Carla Iacobini et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Natural Killer T Cells Are Involved in Adipose Tissues Inflammation and Glucose Intolerance in Diet-Induced Obese Mice

(2009) Kazue Ohmura et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Interleukin-10 Prevents Diet-Induced Insulin Resistance by Attenuating Macrophage and Cytokine Response in Skeletal Muscle

(2009) E.-G. Hong et al.   DIABETES

Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters

(2009) Markus Feuerer et al.   NATURE MEDICINE

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

(2009) Satoshi Nishimura et al.   NATURE MEDICINE

Galectin-3 negatively regulates TCR-mediated CD4+ T-cell activation at the immunological synapse

(2009) H.-Y. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeted disruption of the galectin-3 gene results in decreased susceptibility to multiple low dose streptozotocin-induced diabetes in mice

(2008) E.P.K. Mensah-Brown et al.   CLINICAL IMMUNOLOGY

Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet-Induced Obesity and Diabetes in Mice

(2008) P. D. Cani et al.   DIABETES