Functional screening identifies MCT4 as a key regulator of breast cancer cell metabolism and survival
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Functional screening identifies MCT4 as a key regulator of breast cancer cell metabolism and survival
Authors
Keywords
-
Journal
JOURNAL OF PATHOLOGY
Volume 237, Issue 2, Pages 152-165
Publisher
Wiley
Online
2015-05-12
DOI
10.1002/path.4562
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Expression of the hypoxia-inducible monocarboxylate transporter MCT4 is increased in triple negative breast cancer and correlates independently with clinical outcome
- (2014) J. Doyen et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Antitumor Activity of 7-Aminocarboxycoumarin Derivatives, a New Class of Potent Inhibitors of Lactate Influx but Not Efflux
- (2014) N. Draoui et al. MOLECULAR CANCER THERAPEUTICS
- MCT4 Defines a Glycolytic Subtype of Pancreatic Cancer with Poor Prognosis and Unique Metabolic Dependencies
- (2014) GuemHee Baek et al. Cell Reports
- HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
- (2013) Gregg L. Semenza JOURNAL OF CLINICAL INVESTIGATION
- Metabolic targets for cancer therapy
- (2013) Lorenzo Galluzzi et al. NATURE REVIEWS DRUG DISCOVERY
- Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate
- (2012) Patrick S. Ward et al. CANCER CELL
- New strategies for targeting the hypoxic tumour microenvironment in breast cancer
- (2012) Carol Ward et al. CANCER TREATMENT REVIEWS
- Mitochondrial metabolism in cancer metastasis
- (2012) Federica Sotgia et al. CELL CYCLE
- Using the “reverse Warburg effect” to identify high-risk breast cancer patients
- (2012) Agnieszka K. Witkiewicz et al. CELL CYCLE
- Inhibition of Monocarboxylate Transporter 2 Induces Senescence-Associated Mitochondrial Dysfunction and Suppresses Progression of Colorectal Malignancies In Vivo
- (2012) I. Lee et al. MOLECULAR CANCER THERAPEUTICS
- How cancer metabolism is tuned for proliferation and vulnerable to disruption
- (2012) Almut Schulze et al. NATURE
- Comprehensive molecular portraits of human breast tumours
- (2012) Daniel C. Koboldt et al. NATURE
- Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation
- (2011) Sophia Y. Lunt et al. Annual Review of Cell and Developmental Biology
- Evidence for a stromal-epithelial “lactate shuttle” in human tumors
- (2011) Diana Whitaker-Menezes et al. CELL CYCLE
- Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation
- (2011) A. R. Grassian et al. GENES & DEVELOPMENT
- In vivo pH in metabolic-defective Ras-transformed fibroblast tumors: Key role of the monocarboxylate transporter, MCT4, for inducing an alkaline intracellular pH
- (2011) Johanna Chiche et al. INTERNATIONAL JOURNAL OF CANCER
- Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
- (2011) Brian D. Lehmann et al. JOURNAL OF CLINICAL INVESTIGATION
- Gene expression profiling in breast cancer: classification, prognostication, and prediction
- (2011) Jorge S Reis-Filho et al. LANCET
- Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis
- (2011) Jason W Locasale et al. NATURE GENETICS
- Acidic Environment Leads to ROS-Induced MAPK Signaling in Cancer Cells
- (2011) Anne Riemann et al. PLoS One
- CD147 subunit of lactate/H+ symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumors
- (2011) R. Le Floch et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hypoxia and energetic tumour metabolism
- (2010) M Christiane Brahimi-Horn et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Monocarboxylate transporter 1 is up-regulated in basal-like breast carcinoma
- (2010) Céline Pinheiro et al. HISTOPATHOLOGY
- Diverse somatic mutation patterns and pathway alterations in human cancers
- (2010) Zhengyan Kan et al. NATURE
- HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment
- (2009) Britta Weigelt et al. BREAST CANCER RESEARCH AND TREATMENT
- Supervised Risk Predictor of Breast Cancer Based on Intrinsic Subtypes
- (2009) Joel S. Parker et al. JOURNAL OF CLINICAL ONCOLOGY
- Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment
- (2009) Zachary T. Schafer et al. NATURE
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Tumor-associated Carbonic Anhydrase 9 Spatially Coordinates Intracellular pH in Three-dimensional Multicellular Growths
- (2008) Pawel Swietach et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Disruption of the SRC-1 gene in mice suppresses breast cancer metastasis without affecting primary tumor formation
- (2008) S. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started