Re-purposing Chloroquine for Glioblastoma: Potential Merits and Confounding Variables
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Title
Re-purposing Chloroquine for Glioblastoma: Potential Merits and Confounding Variables
Authors
Keywords
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Journal
Frontiers in Oncology
Volume 8, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2018-08-27
DOI
10.3389/fonc.2018.00335
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Note: Only part of the references are listed.- GBP3 promotes glioma cell proliferation via SQSTM1/p62-ERK1/2 axis
- (2018) Hui Xu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- NF-κB Signaling Activation Induced by Chloroquine Requires Autophagosome, p62 Protein, and c-Jun N-terminal Kinase (JNK) Signaling and Promotes Tumor Cell Resistance
- (2017) Seungwon Yang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Study protocol of a phase IB/II clinical trial of metformin and chloroquine in patients with IDH1 -mutated or IDH2 -mutated solid tumours
- (2017) Remco J Molenaar et al. BMJ Open
- Oxidative stress, mitochondrial abnormalities and antioxidant defense in Ataxia-telangiectasia, Bloom syndrome and Nijmegen breakage syndrome
- (2017) Mateusz Maciejczyk et al. Redox Biology
- Chloroquine, an autophagy inhibitor, potentiates the radiosensitivity of glioma initiating cells by inhibiting autophagy and activating apoptosis
- (2016) Hongxing Ye et al. BMC Neurology
- The autophagy inhibitor chloroquine targets cancer stem cells in triple negative breast cancer by inducing mitochondrial damage and impairing DNA break repair
- (2016) Diana H. Liang et al. CANCER LETTERS
- Inhibition of cholesterol metabolism underlies synergy between mTOR pathway inhibition and chloroquine in bladder cancer cells
- (2016) M A King et al. ONCOGENE
- Effects of primaquine and chloroquine on oxidative stress parameters in rats
- (2015) FRANCIANNE GIOVANELLA et al. ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS
- The synergistic effect of combination temozolomide and chloroquine treatment is dependent on autophagy formation and p53 status in glioma cells
- (2015) Seung Woo Lee et al. CANCER LETTERS
- Selective Inhibition of Parallel DNA Damage Response Pathways Optimizes Radiosensitization of Glioblastoma Stem-like Cells
- (2015) S. U. Ahmed et al. CANCER RESEARCH
- Impact of Autophagy Inhibition at Different Stages on Cytotoxic Effect of Autophagy Inducer in Glioblastoma Cells
- (2015) Chenguang Li et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- p62/SQSTM1 functions as a signaling hub and an autophagy adaptor
- (2015) Yoshinori Katsuragi et al. FEBS Journal
- Cancer stem cells in glioblastoma
- (2015) Justin D. Lathia et al. GENES & DEVELOPMENT
- Impact of nuclear factor erythroid-derived 2–like 2 and p62/sequestosome expression on prognosis of patients with gliomas
- (2015) Mingfei Zhao et al. HUMAN PATHOLOGY
- Chloroquine analogues in drug discovery: new directions of uses, mechanisms of actions and toxic manifestations from malaria to multifarious diseases
- (2015) M. A. A. Al-Bari JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- p53 in survival, death and metabolic health: a lifeguard with a licence to kill
- (2015) Flore Kruiswijk et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Nuclear factor-κB in glioblastoma: insights into regulators and targeted therapy
- (2015) Kirk E. Cahill et al. NEURO-ONCOLOGY
- Loss of autophagy causes a synthetic lethal deficiency in DNA repair
- (2015) Emma Y. Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy
- (2015) Christina H. Eng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- EZH2 Protects Glioma Stem Cells from Radiation-Induced Cell Death in a MELK/FOXM1-Dependent Manner
- (2015) Sung-Hak Kim et al. Stem Cell Reports
- How to teach an old dog new tricks: Autophagy-independent action of chloroquine on the tumor vasculature
- (2014) Hannelore Maes et al. Autophagy
- A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme
- (2014) Myrna R Rosenfeld et al. Autophagy
- Tumor Vessel Normalization by Chloroquine Independent of Autophagy
- (2014) Hannelore Maes et al. CANCER CELL
- Chloroquine potentiates temozolomide cytotoxicity by inhibiting mitochondrial autophagy in glioma cells
- (2014) Yusuke S. Hori et al. JOURNAL OF NEURO-ONCOLOGY
- EANO guideline for the diagnosis and treatment of anaplastic gliomas and glioblastoma
- (2014) Michael Weller et al. LANCET ONCOLOGY
- Chloroquine enhances temozolomide cytotoxicity in malignant gliomas by blocking autophagy
- (2014) Encouse B. Golden et al. Neurosurgical Focus
- Hominoid-specific enzyme GLUD2 promotes growth ofIDH1R132Hglioma
- (2014) Ruihuan Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- FET-PET-based reirradiation and chloroquine in patients with recurrent glioblastoma
- (2014) Angelika Bilger et al. STRAHLENTHERAPIE UND ONKOLOGIE
- Oxidative stress activates a specific p53 transcriptional response that regulates cellular senescence and aging
- (2013) Valentina Gambino et al. AGING CELL
- Chloroquine in Cancer Therapy: A Double-Edged Sword of Autophagy
- (2013) T. Kimura et al. CANCER RESEARCH
- Chloroquine: Modes of action of an undervalued drug
- (2013) Rodolfo Thomé et al. IMMUNOLOGY LETTERS
- Molecular neuro-oncology in clinical practice: a new horizon
- (2013) Michael Weller et al. LANCET ONCOLOGY
- EGFR overexpressing cells and tumors are dependent on autophagy for growth and survival
- (2013) Barry Jutten et al. RADIOTHERAPY AND ONCOLOGY
- The ATM signaling network in development and disease
- (2013) Travis H. Stracker et al. Frontiers in Genetics
- The dual PI3K/mTOR inhibitor NVP-BEZ235 and chloroquine synergize to trigger apoptosisviamitochondrial-lysosomal cross-talk
- (2012) Christian Seitz et al. INTERNATIONAL JOURNAL OF CANCER
- Autophagy and cancer - issues we need to digest
- (2012) E. Y. Liu et al. JOURNAL OF CELL SCIENCE
- Chloroquine or Chloroquine-PI3K/Akt Pathway Inhibitor Combinations Strongly Promote γ-Irradiation-Induced Cell Death in Primary Stem-Like Glioma Cells
- (2012) Elke Firat et al. PLoS One
- Chloroquine inhibits glutamate-induced death of a neuronal cell line by reducing reactive oxygen species through sigma-1 receptor
- (2011) Yoko Hirata et al. JOURNAL OF NEUROCHEMISTRY
- Chloroquine activates the p53 pathway and induces apoptosis in human glioma cells
- (2011) E. L. Kim et al. NEURO-ONCOLOGY
- Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas
- (2010) Christian Hartmann et al. ACTA NEUROPATHOLOGICA
- The induction of autophagy by γ-radiation contributes to the radioresistance of glioma stem cells
- (2009) Stephanie L. Lomonaco et al. INTERNATIONAL JOURNAL OF CANCER
- Comprehensive genomic characterization defines human glioblastoma genes and core pathways
- (2008) Roger McLendon et al. NATURE
- Chloroquine mediated molecular tuning of astrocytes for enhanced permissiveness to HIV infection
- (2008) Theophilus S. Vijaykumar et al. VIROLOGY
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