Histones and Their Modifications in Ovarian Cancer – Drivers of Disease and Therapeutic Targets
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Histones and Their Modifications in Ovarian Cancer – Drivers of Disease and Therapeutic Targets
Authors
Keywords
-
Journal
Frontiers in Oncology
Volume 4, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2014-06-12
DOI
10.3389/fonc.2014.00144
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Nature as a remarkable chemist
- (2014) Mansukh C. Wani et al. ANTI-CANCER DRUGS
- Writing and reading H2B monoubiquitylation
- (2014) Gilad Fuchs et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Abstract A29: Loss of histone H2B monoubiquitination in ovarian cancer – new therapeutic targeting opportunities based on chromatin relaxation
- (2014) Deborah J. Marsh et al. CLINICAL CANCER RESEARCH
- Overexpression of long non-coding RNA HOTAIR predicts poor patient prognosis and promotes tumor metastasis in epithelial ovarian cancer
- (2014) Jun-jun Qiu et al. GYNECOLOGIC ONCOLOGY
- At the tipping point for epigenetic therapies in cancer
- (2014) Peter A. Jones JOURNAL OF CLINICAL INVESTIGATION
- Predicting response to epigenetic therapy
- (2014) Marianne B. Treppendahl et al. JOURNAL OF CLINICAL INVESTIGATION
- The multilayered complexity of ceRNA crosstalk and competition
- (2014) Yvonne Tay et al. NATURE
- Beyond Breast and Ovarian Cancers: PARP Inhibitors for BRCA Mutation-Associated and BRCA-Like Solid Tumors
- (2014) Ciara C. O’Sullivan et al. Frontiers in Oncology
- Effects of Valproic Acid on Proliferation, Apoptosis, Angiogenesis and Metastasis of Ovarian Cancer in Vitro and in Vivo
- (2013) Zhao Shan et al. Asian Pacific Journal of Cancer Prevention
- 3-Deazaneplanocin A is a Promising Therapeutic Agent for Ovarian Cancer Cells
- (2013) Liang Shen et al. Asian Pacific Journal of Cancer Prevention
- Transformation of the Fallopian Tube Secretory Epithelium Leads to High-Grade Serous Ovarian Cancer in Brca;Tp53;Pten Models
- (2013) Ruth Perets et al. CANCER CELL
- EZH2 blockade by RNA interference inhibits growth of ovarian cancer by facilitating re-expression of p21waf1/cip1 and by inhibiting mutant p53
- (2013) Shelly Seward et al. CANCER LETTERS
- Histone variants: emerging players in cancer biology
- (2013) Chiara Vardabasso et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- BRCA1 is a negative modulator of the PRC2 complex
- (2013) Lan Wang et al. EMBO JOURNAL
- Patterns of chemotherapy treatment for women with invasive epithelial ovarian cancer – A population-based study
- (2013) S. Jordan et al. GYNECOLOGIC ONCOLOGY
- Neoadjuvant chemotherapy with six cycles of carboplatin and paclitaxel in advanced ovarian cancer patients unsuitable for primary surgery: Safety and effectiveness
- (2013) Vanessa da Costa Miranda et al. GYNECOLOGIC ONCOLOGY
- The long non-coding RNA HOTAIR is upregulated in endometrial carcinoma and correlates with poor prognosis
- (2013) XIAOYING HE et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Conversations between chromatin modifications and DNA double strand break repair: A commentary
- (2013) Michael J. Hendzel et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Targeted disruption of the EZH2–EED complex inhibits EZH2-dependent cancer
- (2013) Woojin Kim et al. Nature Chemical Biology
- miRTarBase update 2014: an information resource for experimentally validated miRNA-target interactions
- (2013) Sheng-Da Hsu et al. NUCLEIC ACIDS RESEARCH
- Long Noncoding RNA HOTAIR Is a Prognostic Marker for Esophageal Squamous Cell Carcinoma Progression and Survival
- (2013) Xiao-Bin Lv et al. PLoS One
- The Anti-Tumor Effects and Molecular Mechanisms of Suberoylanilide Hydroxamic Acid (SAHA) on the Aggressive Phenotypes of Ovarian Carcinoma Cells
- (2013) Shuo Chen et al. PLoS One
- Brief Report: The lincRNA Hotair Is Required for Epithelial-to-Mesenchymal Transition and Stemness Maintenance of Cancer Cell Lines
- (2013) Cleidson Pádua Alves et al. STEM CELLS
- The emerging and diverse roles of sirtuins in cancer: a clinical perspective
- (2013) WenYong Chen et al. OncoTargets and Therapy
- Evaluating cell lines as tumour models by comparison of genomic profiles
- (2013) Silvia Domcke et al. Nature Communications
- Mechanisms of Resistance to PARP Inhibitors—Three and Counting
- (2013) Tito Fojo et al. Cancer Discovery
- PRIMA-1 increases cisplatin sensitivity in chemoresistant ovarian cancer cells with p53 mutation: a requirement for Akt down-regulation
- (2013) Noriko Kobayashi et al. Journal of Ovarian Research
- Enhanced Cytotoxic Effects of Combined Valproic Acid and the Aurora Kinase Inhibitor VE465 on Gynecologic Cancer Cells
- (2013) Yanfang Li et al. Frontiers in Oncology
- Role of EZH2 in Epithelial Ovarian Cancer: From Biological Insights to Therapeutic Target
- (2013) Hua Li et al. Frontiers in Oncology
- The COMPASS Family of Histone H3K4 Methylases: Mechanisms of Regulation in Development and Disease Pathogenesis
- (2012) Ali Shilatifard Annual Review of Biochemistry
- A Small Molecule Inhibitor of Ubiquitin-Specific Protease-7 Induces Apoptosis in Multiple Myeloma Cells and Overcomes Bortezomib Resistance
- (2012) Dharminder Chauhan et al. CANCER CELL
- HER2 Overexpression Renders Human Breast Cancers Sensitive to PARP Inhibition Independently of Any Defect in Homologous Recombination DNA Repair
- (2012) S. Nowsheen et al. CANCER RESEARCH
- Cancer Epigenetics: From Mechanism to Therapy
- (2012) Mark A. Dawson et al. CELL
- Shaping the landscape: mechanistic consequences of ubiquitin modification of chromatin
- (2012) Sigurd Braun et al. EMBO REPORTS
- The enigmatic role of H2Bub1 in cancer
- (2012) Steven A. Johnsen FEBS LETTERS
- Targeting the epigenome in ovarian cancer
- (2012) Susan K Murphy Future Oncology
- Romidepsin (FK228) combined with cisplatin stimulates DNA damage-induced cell death in ovarian cancer
- (2012) Andrew J. Wilson et al. GYNECOLOGIC ONCOLOGY
- Clinical trials and future potential of targeted therapy for ovarian cancer
- (2012) Hiroaki Itamochi et al. International Journal of Clinical Oncology
- Synergistic effects of suberoylanilide hydroxamic acid combined with cisplatin causing cell cycle arrest independent apoptosis in platinum-resistant ovarian cancer cells
- (2012) Paul Ho INTERNATIONAL JOURNAL OF ONCOLOGY
- Cancerous ovarian stem cells: Obscure targets for therapy but relevant to chemoresistance
- (2012) Nuzhat Ahmed et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- BRCA Mutation Frequency and Patterns of Treatment Response in BRCA Mutation–Positive Women With Ovarian Cancer: A Report From the Australian Ovarian Cancer Study Group
- (2012) Kathryn Alsop et al. JOURNAL OF CLINICAL ONCOLOGY
- Secondary mutations inBRCA2associated with clinical resistance to a PARP inhibitor
- (2012) Louise J Barber et al. JOURNAL OF PATHOLOGY
- Synergistic antileukemic action of a combination of inhibitors of DNA methylation and histone methylation
- (2012) Richard L. Momparler et al. LEUKEMIA RESEARCH
- Molecular Mechanisms Involved in the Synergistic Interaction of the EZH2 Inhibitor 3-Deazaneplanocin A with Gemcitabine in Pancreatic Cancer Cells
- (2012) A. Avan et al. MOLECULAR CANCER THERAPEUTICS
- EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations
- (2012) Michael T. McCabe et al. NATURE
- A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells
- (2012) Sarah K Knutson et al. Nature Chemical Biology
- Targeting Epigenetic Readers in Cancer
- (2012) Mark A. Dawson et al. NEW ENGLAND JOURNAL OF MEDICINE
- Chromatin H3K27me3/H3K4me3 histone marks define gene sets in high-grade serous ovarian cancer that distinguish malignant, tumour-sustaining and chemo-resistant ovarian tumour cells
- (2012) N Chapman-Rothe et al. ONCOGENE
- Candidate DNA methylation drivers of acquired cisplatin resistance in ovarian cancer identified by methylome and expression profiling
- (2012) C Zeller et al. ONCOGENE
- HOTAIR is a negative prognostic factor and exhibits pro-oncogenic activity in pancreatic cancer
- (2012) K Kim et al. ONCOGENE
- Long non-coding RNAs and cancer: a new frontier of translational research?
- (2012) R Spizzo et al. ONCOGENE
- Coupling of Glucose Deprivation with Impaired Histone H2B Monoubiquitination in Tumors
- (2012) Yasuyo Urasaki et al. PLoS One
- Selective inhibition of Ezh2 by a small molecule inhibitor blocks tumor cells proliferation
- (2012) W. Qi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeting Notch, a key pathway for ovarian cancer stem cells, sensitizes tumors to platinum therapy
- (2012) S. M. McAuliffe et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The hallmarks of cancer
- (2012) Tony Gutschner et al. RNA Biology
- Thailandepsins are new small molecule class I HDAC inhibitors with potent cytotoxic activity in ovarian cancer cells: a preclinical study of epigenetic ovarian cancer therapy
- (2012) Andrew J Wilson et al. Journal of Ovarian Research
- The role of PARP1 in the DNA damage response and its application in tumor therapy
- (2012) Zhifeng Wang et al. Frontiers of Medicine
- Biochemical, Molecular and Epigenetic Mechanisms of Valproic Acid Neuroprotection
- (2012) Barbara Monti et al. Current Molecular Pharmacology
- The role of poly adenosine diphosphate ribose polymerase inhibitors in breast and ovarian cancer: Current status and future directions
- (2011) Fiona CHIONH et al. Asia-Pacific Journal of Clinical Oncology
- Chatting histone modifications in mammals
- (2011) A. Izzo et al. Briefings in Functional Genomics
- Decitabine and suberoylanilide hydroxamic acid (SAHA) inhibit growth of ovarian cancer cell lines and xenografts while inducing expression of imprinted tumor suppressor genes, apoptosis, G2/M arrest, and autophagy
- (2011) Min-Yu Chen et al. CANCER
- The effect of the histone deacetylase inhibitor M344 on BRCA1 expression in breast and ovarian cancer cells
- (2011) Johanne I Weberpals et al. Cancer Cell International
- Estrogen-Dependent Gene Transcription in Human Breast Cancer Cells Relies upon Proteasome-Dependent Monoubiquitination of Histone H2B
- (2011) T. Prenzel et al. CANCER RESEARCH
- Long Noncoding RNA HOTAIR Regulates Polycomb-Dependent Chromatin Modification and Is Associated with Poor Prognosis in Colorectal Cancers
- (2011) R. Kogo et al. CANCER RESEARCH
- Chromatin Connections to Pluripotency and Cellular Reprogramming
- (2011) Stuart H. Orkin et al. CELL
- The Multifaceted Roles of USP7: New Therapeutic Opportunities
- (2011) Benjamin Nicholson et al. CELL BIOCHEMISTRY AND BIOPHYSICS
- An acetylation-monoubiquitination switch on Lysine 120 of H2B
- (2011) Raffaella Gatta et al. Epigenetics
- Profiling of linker histone variants in ovarian cancer
- (2011) Magdalena Medrzycki Frontiers in Bioscience-Landmark
- The tumor suppressor CDC73 interacts with the ring finger proteins RNF20 and RNF40 and is required for the maintenance of histone 2B monoubiquitination
- (2011) Michael A. Hahn et al. HUMAN MOLECULAR GENETICS
- Epigenetic Regulation of Cancer-Associated Genes in Ovarian Cancer
- (2011) Mi Jeong Kwon et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- QKI-Mediated Alternative Splicing of the Histone Variant MacroH2A1 Regulates Cancer Cell Proliferation
- (2011) L. Novikov et al. MOLECULAR AND CELLULAR BIOLOGY
- Ovarian Cancer Stem Cell-Like Side Populations Are Enriched Following Chemotherapy and Overexpress EZH2
- (2011) S. Rizzo et al. MOLECULAR CANCER THERAPEUTICS
- Regulation of Homologous Recombination by RNF20-Dependent H2B Ubiquitination
- (2011) Kyosuke Nakamura et al. MOLECULAR CELL
- The Polycomb complex PRC2 and its mark in life
- (2011) Raphaël Margueron et al. NATURE
- Integrated genomic analyses of ovarian carcinoma
- (2011) D. Bell et al. NATURE
- Regulation of u-PAR gene expression by H2A.Z is modulated by the MEK–ERK/AP-1 pathway
- (2011) Santosh Chauhan et al. NUCLEIC ACIDS RESEARCH
- Prevalence of Epithelial Ovarian Cancer Stem Cells Correlates with Recurrence in Early-Stage Ovarian Cancer
- (2011) Karina Dahl Steffensen et al. Journal of Oncology
- The therapeutic potential of deubiquitinating enzyme inhibitors
- (2010) Frédéric Colland BIOCHEMICAL SOCIETY TRANSACTIONS
- Cancer Statistics, 2010
- (2010) A. Jemal et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Overexpression of EZH2 contributes to acquired cisplatin resistance in ovarian cancer cells in vitro and in vivo
- (2010) Sha Hu et al. CANCER BIOLOGY & THERAPY
- EZH2 supports ovarian carcinoma cell invasion and/or metastasis via regulation of TGF-β1 and is a predictor of outcome in ovarian carcinoma patients
- (2010) Zhi-Yue Rao et al. CARCINOGENESIS
- The Language of Histone Crosstalk
- (2010) Jung-Shin Lee et al. CELL
- A MicroRNA Targeting Dicer for Metastasis Control
- (2010) Graziano Martello et al. CELL
- Epigenetics of ovarian cancer: From the lab to the clinic
- (2010) Reza Asadollahi et al. GYNECOLOGIC ONCOLOGY
- Type-specific roles of histone deacetylase (HDAC) overexpression in ovarian carcinoma: HDAC1 enhances cell proliferation and HDAC3 stimulates cell migration with downregulation of E-cadherin
- (2010) Akiko Hayashi et al. INTERNATIONAL JOURNAL OF CANCER
- Consolidation Therapy in Ovarian Cancer
- (2010) Paul Sabbatini INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
- Identification of aberrant promoter hypomethylation of HOXA10 in ovarian cancer
- (2010) Wenjun Cheng et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- The Chromatin Signaling Pathway: Diverse Mechanisms of Recruitment of Histone-Modifying Enzymes and Varied Biological Outcomes
- (2010) Edwin Smith et al. MOLECULAR CELL
- The DNA Damage Response: Making It Safe to Play with Knives
- (2010) Alberto Ciccia et al. MOLECULAR CELL
- Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
- (2010) Rajnish A. Gupta et al. NATURE
- Histone variants — ancient wrap artists of the epigenome
- (2010) Paul B. Talbert et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes
- (2010) M.-C. Tsai et al. SCIENCE
- RAD6-Mediated Transcription-Coupled H2B Ubiquitylation Directly Stimulates H3K4 Methylation in Human Cells
- (2009) Jaehoon Kim et al. CELL
- Minireview: Epigenetic Changes in Ovarian Cancer
- (2009) Curt Balch et al. ENDOCRINOLOGY
- Histone H2A.Z is essential for estrogen receptor signaling
- (2009) N. Gevry et al. GENES & DEVELOPMENT
- Suberoylanilide hydroxamic acid (SAHA) potentiates paclitaxel-induced apoptosis in ovarian cancer cell lines
- (2009) Charles S. Dietrich et al. GYNECOLOGIC ONCOLOGY
- DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation
- (2009) T. B. Miranda et al. MOLECULAR CANCER THERAPEUTICS
- Mir-214-Dependent Regulation of the Polycomb Protein Ezh2 in Skeletal Muscle and Embryonic Stem Cells
- (2009) Aster H. Juan et al. MOLECULAR CELL
- Long non-coding RNAs: insights into functions
- (2009) Tim R. Mercer et al. NATURE REVIEWS GENETICS
- Expression and prognostic significance of SIRT1 in ovarian epithelial tumours
- (2009) Kyu Yun Jang et al. PATHOLOGY
- Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression
- (2009) Ahmad M. Khalil et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Nucleosome Family: Dynamic and Growing
- (2009) Jordanka Zlatanova et al. STRUCTURE
- Histone Deacetylase Inhibitor Therapy in Epithelial Ovarian Cancer
- (2009) Noriyuki Takai et al. Journal of Oncology
- Valproic acid resensitizes cisplatin-resistant ovarian cancer cells
- (2008) Ching-Tai Lin et al. CANCER SCIENCE
- Unraveling Epigenetic Regulation in Embryonic Stem Cells
- (2008) Marina Bibikova et al. Cell Stem Cell
- Novel Molecular Subtypes of Serous and Endometrioid Ovarian Cancer Linked to Clinical Outcome
- (2008) R. W. Tothill et al. CLINICAL CANCER RESEARCH
- Diagnostic Markers for Early Detection of Ovarian Cancer
- (2008) I. Visintin et al. CLINICAL CANCER RESEARCH
- MicroRNA Expression Profiles in Serous Ovarian Carcinoma
- (2008) E. J. Nam et al. CLINICAL CANCER RESEARCH
- A phase II study of vorinostat in the treatment of persistent or recurrent epithelial ovarian or primary peritoneal carcinoma: A Gynecologic Oncology Group study
- (2008) Susan C. Modesitt et al. GYNECOLOGIC ONCOLOGY
- MicroRNA-26a Targets the Histone MethyltransferaseEnhancer of Zeste homolog 2during Myogenesis
- (2008) Chung Fai Wong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- New Insights Into the Pathogenesis of Serous Ovarian Cancer and Its Clinical Impact
- (2008) Keren Levanon et al. JOURNAL OF CLINICAL ONCOLOGY
- Trichostatin A up-regulates p73 and induces Bax-dependent apoptosis in cisplatin-resistant ovarian cancer cells
- (2008) Michela Muscolini et al. MOLECULAR CANCER THERAPEUTICS
- Loss of trimethylation at lysine 27 of histone H3 is a predictor of poor outcome in breast, ovarian, and pancreatic cancers
- (2008) Yongkun Wei et al. MOLECULAR CARCINOGENESIS
- Interaction of the Glucocorticoid Receptor with the Chromatin Landscape
- (2008) Sam John et al. MOLECULAR CELL
- Interplay among BRCA1, SIRT1, and Survivin during BRCA1-Associated Tumorigenesis
- (2008) Rui-Hong Wang et al. MOLECULAR CELL
- Epigenetic regulation of CD133 and tumorigenicity of CD133+ ovarian cancer cells
- (2008) T Baba et al. ONCOGENE
- Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer
- (2008) L. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now