Shaping the landscape: mechanistic consequences of ubiquitin modification of chromatin

The Cul4-Ddb1Cdt2 Ubiquitin Ligase Inhibits Invasion of a Boundary-Associated Antisilencing Factor into Heterochromatin

(2011) Sigurd Braun et al.   CELL

The F Box Protein Partner of Paired Regulates Stability of Drosophila Centromeric Histone H3, CenH3CID

(2011) Olga Moreno-Moreno et al.   CURRENT BIOLOGY

Gene expression control by protein deubiquitinases

(2011) Lori Frappier et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Structural regulation of cullin-RING ubiquitin ligase complexes

(2011) David M Duda et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

The Arabidopsis CUL4-DDB1 complex interacts with MSI1 and is required to maintainMEDEAparental imprinting

(2011) Eva Dumbliauskas et al.   EMBO JOURNAL

Mechanism of CRL4Cdt2, a PCNA-dependent E3 ubiquitin ligase

(2011) C. G. Havens et al.   GENES & DEVELOPMENT

Genome-wide function of H2B ubiquitylation in promoter and genic regions

(2011) K. Batta et al.   GENES & DEVELOPMENT

The SKP1-Cul1-F-box and Leucine-rich Repeat Protein 4 (SCF-FbxL4) Ubiquitin Ligase Regulates Lysine Demethylase 4A (KDM4A)/Jumonji Domain-containing 2A (JMJD2A) Protein

(2011) Capucine Van Rechem et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SET8 is degraded via PCNA-coupled CRL4(CDT2) ubiquitylation in S phase and after UV irradiation

(2011) Stine Jørgensen et al.   JOURNAL OF CELL BIOLOGY

RNF20 Inhibits TFIIS-Facilitated Transcriptional Elongation to Suppress Pro-oncogenic Gene Expression

(2011) Efrat Shema et al.   MOLECULAR CELL

The RING Finger Protein MSL2 in the MOF Complex Is an E3 Ubiquitin Ligase for H2B K34 and Is Involved in Crosstalk with H3 K4 and K79 Methylation

(2011) Lipeng Wu et al.   MOLECULAR CELL

BRCA1 tumour suppression occurs via heterochromatin-mediated silencing

(2011) Quan Zhu et al.   NATURE

Histone H2B ubiquitylation disrupts local and higher-order chromatin compaction

(2011) Beat Fierz et al.   Nature Chemical Biology

Hsk1- and SCFPof3-Dependent Proteolysis of S. pombe Ams2 Ensures Histone Homeostasis and Centromere Function

(2010) Yuko Takayama et al.   DEVELOPMENTAL CELL

Cul8/Rtt101 Forms a Variety of Protein Complexes That Regulate DNA Damage Response and Transcriptional Silencing

(2010) Satoru Mimura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activity of a C-terminal Plant Homeodomain (PHD) of Msc1 Is Essential for Function

(2010) Xinxing Qiu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Psh1 Is an E3 Ubiquitin Ligase that Targets the Centromeric Histone Variant Cse4

(2010) Geetha Hewawasam et al.   MOLECULAR CELL

An E3 Ubiquitin Ligase Prevents Ectopic Localization of the Centromeric Histone H3 Variant via the Centromere Targeting Domain

(2010) Prerana Ranjitkar et al.   MOLECULAR CELL

Regulation of the Histone H4 Monomethylase PR-Set7 by CRL4Cdt2-Mediated PCNA-Dependent Degradation during DNA Damage

(2010) Hisanobu Oda et al.   MOLECULAR CELL

CRL4Cdt2-Mediated Destruction of the Histone Methyltransferase Set8 Prevents Premature Chromatin Compaction in S Phase

(2010) Richard C. Centore et al.   MOLECULAR CELL

CRL4Cdt2 Regulates Cell Proliferation and Histone Gene Expression by Targeting PR-Set7/Set8 for Degradation

(2010) Tarek Abbas et al.   MOLECULAR CELL

Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB

(2010) Johanna C. Scheuermann et al.   NATURE

Transcriptional activation of polycomb-repressed genes by ZRF1

(2010) Holger Richly et al.   NATURE

The histone H4 Lys 20 methyltransferase PR-Set7 regulates replication origins in mammalian cells

(2010) Mathieu Tardat et al.   NATURE CELL BIOLOGY

Involvement of Elongin C in the spread of repressive histone modifications

(2010) Tomohito Yamasaki et al.   PLANT JOURNAL

UBR2 mediates transcriptional silencing during spermatogenesis via histone ubiquitination

(2010) J. Y. An et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of DIM-7, a protein required to target the DIM-5 H3 methyltransferase to chromatin

(2010) Z. A. Lewis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polycomb Group Targeting through Different Binding Partners of RING1B C-Terminal Domain

(2010) Renjing Wang et al.   STRUCTURE

DNA Methylation and Normal Chromosome Behavior in Neurospora Depend on Five Components of a Histone Methyltransferase Complex, DCDC

(2010) Zachary A. Lewis et al.   PLoS Genetics

DCAF26, an Adaptor Protein of Cul4-Based E3, Is Essential for DNA Methylation in Neurospora crassa

(2010) Hui Xu et al.   PLoS Genetics

Polyubiquitination of the demethylase Jhd2 controls histone methylation and gene expression

(2009) D. P. Mersman et al.   GENES & DEVELOPMENT

Interaction of APC/C-E3 Ligase with Swi6/HP1 and Clr4/Suv39 in Heterochromatin Assembly in Fission Yeast

(2009) Rudra Narayan Dubey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone Variant H2A.Z Regulates Centromere Silencing and Chromosome Segregation in Fission Yeast

(2009) Haitong Hou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ubiquitin Ligase Components Cullin4 and DDB1 Are Essential for DNA Methylation inNeurospora crassa

(2009) Yuanbiao Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone H2A.Z cooperates with RNAi and heterochromatin factors to suppress antisense RNAs

(2009) Martin Zofall et al.   NATURE

Role of the polycomb protein EED in the propagation of repressive histone marks

(2009) Raphael Margueron et al.   NATURE

Building ubiquitin chains: E2 enzymes at work

(2009) Yihong Ye et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

In Brief

(2009)   NATURE REVIEWS NEUROSCIENCE

Msc1 links dynamic Swi6/HP1 binding to cell fate determination

(2009) R. J. Lawrence et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ubiquitination of histone H2B regulates chromatin dynamics by enhancing nucleosome stability

(2009) M. B. Chandrasekharan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Schizosaccharomyces pombe JmjC-Protein, Msc1, Prevents H2A.Z Localization in Centromeric and Subtelomeric Chromatin Domains

(2009) Luke Buchanan et al.   PLoS Genetics

Deubiquitylation of histone H2A activates transcriptional initiation via trans-histone cross-talk with H3K4 di- and trimethylation

(2008) T. Nakagawa et al.   GENES & DEVELOPMENT

dKDM2 couples histone H2A ubiquitylation to histone H3 demethylation during Polycomb group silencing

(2008) A. Lagarou et al.   GENES & DEVELOPMENT

Polyubiquitylation of Histone H2B

(2008) Fuqiang Geng et al.   MOLECULAR BIOLOGY OF THE CELL

Histone Ubiquitination: Triggering Gene Activity

(2008) Vikki M. Weake et al.   MOLECULAR CELL

H2B Ubiquitylation Plays a Role in Nucleosome Dynamics during Transcription Elongation

(2008) Alastair B. Fleming et al.   MOLECULAR CELL

Histone H2A Monoubiquitination Represses Transcription by Inhibiting RNA Polymerase II Transcriptional Elongation

(2008) Wenlai Zhou et al.   MOLECULAR CELL

Ubiquitylation of the COMPASS component Swd2 links H2B ubiquitylation to H3K4 trimethylation

(2008) Adeline Vitaliano-Prunier et al.   NATURE CELL BIOLOGY

Drosophila Stem Cells Share a Common Requirement for the Histone H2B Ubiquitin Protease Scrawny

(2008) M. Buszczak et al.   SCIENCE