Biotensegrity of the Extracellular Matrix: Physiology, Dynamic Mechanical Balance, and Implications in Oncology and Mechanotherapy

Catch Me Because You Can: A Mathematical Model for Mechanosensing

(2013) Ulrich S. Schwarz   BIOPHYSICAL JOURNAL

Quantifiable diagnosis of muscular dystrophies and neurogenic atrophies through network analysis

(2013) Aurora Sáez et al.   BMC Medicine

Treatment-induced secretion of WNT16B promotes tumor growth and acquired resistance to chemotherapy

(2013) Linda M. Johnson et al.   CANCER BIOLOGY & THERAPY

Mechanisms of action of tasquinimod on the tumour microenvironment

(2013) E. Raymond et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

TLR9 Signaling in the Tumor Microenvironment Initiates Cancer Recurrence after Radiotherapy

(2013) C. Gao et al.   CANCER RESEARCH

Modulation of Nuclear Shape by Substrate Rigidity

(2013) David B. Lovett et al.   Cellular and Molecular Bioengineering

Myosin II in mechanotransduction: master and commander of cell migration, morphogenesis, and cancer

(2013) Rocío Aguilar-Cuenca et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Cadherin mechanotransduction in tissue remodeling

(2013) Floor Twiss et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mechano-Regulation of Alternative Splicing

(2013) Huan Liu et al.   CURRENT GENOMICS

Guiding cell migration by tugging

(2013) Sergey V Plotnikov et al.   CURRENT OPINION IN CELL BIOLOGY

Integrins in mechanotransduction

(2013) Tyler D Ross et al.   CURRENT OPINION IN CELL BIOLOGY

Physical break-down of the classical view on cancer cell invasion and metastasis

(2013) Claudia T. Mierke   EUROPEAN JOURNAL OF CELL BIOLOGY

Maspin influences response to doxorubicin by changing the tumor microenvironment organization

(2013) Tiziana Triulzi et al.   INTERNATIONAL JOURNAL OF CANCER

Neuromuscular disease classification system

(2013) Aurora Sáez et al.   JOURNAL OF BIOMEDICAL OPTICS

Biological effects of cellular stretch on human dermal fibroblasts

(2013) Chenyu Huang et al.   Journal of Plastic Reconstructive and Aesthetic Surgery

Up-regulation of type I collagen during tumorigenesis of colorectal cancer revealed by quantitative proteomic analysis

(2013) Xia Zou et al.   Journal of Proteomics

Quantitative modeling of clinical, cellular and extracellular matrix variables suggest prognostic indicators in cancer: a model in neuroblastoma

(2013) Irene Tadeo et al.   PEDIATRIC RESEARCH

Topological Progression in Proliferating Epithelia Is Driven by a Unique Variation in Polygon Distribution

(2013) Daniel Sánchez-Gutiérrez et al.   PLoS One

Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation

(2013) J. Swift et al.   SCIENCE

Cooperation and competition in the dynamics of tissue architecture during homeostasis and tumorigenesis

(2013) Attila Csikász-Nagy et al.   SEMINARS IN CANCER BIOLOGY

Strategies to Increase Drug Penetration in Solid Tumors

(2013) Il-Kyu Choi et al.   Frontiers in Oncology

Segmental chromosomal alterations have prognostic impact in neuroblastoma: a report from the INRG project

(2012) G Schleiermacher et al.   BRITISH JOURNAL OF CANCER

Molecular Pathways: Involving Microenvironment Damage Responses in Cancer Therapy Resistance

(2012) Y. Sun et al.   CLINICAL CANCER RESEARCH

Connecting the nucleus to the cytoskeleton by SUN–KASH bridges across the nuclear envelope

(2012) Erin C Tapley et al.   CURRENT OPINION IN CELL BIOLOGY

Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B

(2012) Yu Sun et al.   NATURE MEDICINE

Independent regulation of tumor cell migration by matrix stiffness and confinement

(2012) A. Pathak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The mesenchymal tumor microenvironment

(2012) Edna Cukierman et al.   Cell Adhesion & Migration

Nesprin-3: a versatile connector between the nucleus and the cytoskeleton

(2011) Mirjam Ketema et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Bcl-2 Family Genetic Profiling Reveals Microenvironment-Specific Determinants of Chemotherapeutic Response

(2011) J. R. Pritchard et al.   CANCER RESEARCH

The Interaction between Nesprins and Sun Proteins at the Nuclear Envelope Is Critical for Force Transmission between the Nucleus and Cytoskeleton

(2011) Maria L. Lombardi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extracellular matrix and cell signalling: the dynamic cooperation of integrin, proteoglycan and growth factor receptor

(2011) Soo-Hyun Kim et al.   JOURNAL OF ENDOCRINOLOGY

Nesprin-3 regulates endothelial cell morphology, perinuclear cytoskeletal architecture, and flow-induced polarization

(2011) Joshua T. Morgan et al.   MOLECULAR BIOLOGY OF THE CELL

Balancing forces: architectural control of mechanotransduction

(2011) Christopher C. DuFort et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cell-ECM traction force modulates endogenous tension at cell-cell contacts

(2011) V. Maruthamuthu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epithelial organisation revealed by a network of cellular contacts

(2011) Luis M. Escudero et al.   Nature Communications

An in silico platform for the study of epithelial pre-invasive neoplastic development

(2010) Martial Guillaud et al.   BIOSYSTEMS

Vinculin potentiates E-cadherin mechanosensing and is recruited to actin-anchored sites within adherens junctions in a myosin II–dependent manner

(2010) Quint le Duc et al.   JOURNAL OF CELL BIOLOGY

Accumulation of Segmental Alterations Determines Progression in Neuroblastoma

(2010) Gudrun Schleiermacher et al.   JOURNAL OF CLINICAL ONCOLOGY

The dual role of the extracellular matrix in synaptic plasticity and homeostasis

(2010) Alexander Dityatev et al.   NATURE REVIEWS NEUROSCIENCE

Mechanical tugging force regulates the size of cell-cell junctions

(2010) Z. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Linear Arrays of Nuclear Envelope Proteins Harness Retrograde Actin Flow for Nuclear Movement

(2010) G. W. G. Luxton et al.   SCIENCE

Tensegrin in context

(2010) Ramin Zargham   Cell Adhesion & Migration

Integrin α8β1 regulates adhesion, migration and proliferation of human intestinal crypt cells via a predominant RhoA/ROCK-dependent mechanism

(2009) Yannick D. Benoit et al.   BIOLOGY OF THE CELL

Follicular lymphoma cells induce T-cell immunologic synapse dysfunction that can be repaired with lenalidomide: implications for the tumor microenvironment and immunotherapy

(2009) A. G. Ramsay et al.   BLOOD

Alterations in regulators of the extracellular matrix in non-Hodgkin lymphomas

(2009) Helene F. S. Negaard et al.   LEUKEMIA & LYMPHOMA

Regulation of cell signalling by uPAR

(2009) Harvey W. Smith et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Nesprin 4 is an outer nuclear membrane protein that can induce kinesin-mediated cell polarization

(2009) K. J. Roux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epithelial mesenchymal transition traits in human breast cancer cell lines

(2008) T. Blick et al.   CLINICAL & EXPERIMENTAL METASTASIS

Molecular signature and therapeutic perspective of the epithelial-to-mesenchymal transitions in epithelial cancers

(2008) Michèle Sabbah et al.   DRUG RESISTANCE UPDATES

Mechanotransduction - a field pulling together?

(2008) C. S. Chen   JOURNAL OF CELL SCIENCE

The International Neuroblastoma Risk Group (INRG) Classification System: An INRG Task Force Report

(2008) Susan L. Cohn et al.   JOURNAL OF CLINICAL ONCOLOGY

Tensegrity-based mechanosensing from macro to micro

(2008) Donald E. Ingber   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY