Modulation of Nuclear Shape by Substrate Rigidity

Extracellular-matrix tethering regulates stem-cell fate

(2012) Britta Trappmann et al.   NATURE MATERIALS

Regulation of the Matrix Microenvironment for Stem Cell Engineering and Regenerative Medicine

(2011) Ngan F. Huang et al.   ANNALS OF BIOMEDICAL ENGINEERING

Nesprin-3: a versatile connector between the nucleus and the cytoskeleton

(2011) Mirjam Ketema et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Synergistic regulation of cell function by matrix rigidity and adhesive pattern

(2011) Shinuo Weng et al.   BIOMATERIALS

Stress fibers stabilize the position of intranuclear DNA through mechanical connection with the nucleus in vascular smooth muscle cells

(2011) Kazuaki Nagayama et al.   FEBS LETTERS

Structure of Sad1-UNC84 Homology (SUN) Domain Defines Features of Molecular Bridge in Nuclear Envelope

(2011) Zhaocai Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Interaction between Nesprins and Sun Proteins at the Nuclear Envelope Is Critical for Force Transmission between the Nucleus and Cytoskeleton

(2011) Maria L. Lombardi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The nucleoskeleton as a genome-associated dynamic 'network of networks'

(2011) Dan N. Simon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Acto-myosin based response to stiffness and rigidity sensing

(2011) Jonathan Fouchard et al.   Cell Adhesion & Migration

Interactions Between Nuclei and the Cytoskeleton Are Mediated by SUN-KASH Nuclear-Envelope Bridges

(2010) Daniel A. Starr et al.   Annual Review of Cell and Developmental Biology

Nuclear morphology and deformation in engineered cardiac myocytes and tissues

(2010) Mark-Anthony P. Bray et al.   BIOMATERIALS

Actomyosin Tension Exerted on the Nucleus through Nesprin-1 Connections Influences Endothelial Cell Adhesion, Migration, and Cyclic Strain-Induced Reorientation

(2010) T.J. Chancellor et al.   BIOPHYSICAL JOURNAL

Interfering with the connection between the nucleus and the cytoskeleton affects nuclear rotation, mechanotransduction and myogenesis

(2010) Michaela Brosig et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Matrix elasticity, cytoskeletal forces and physics of the nucleus: how deeply do cells 'feel' outside and in?

(2010) A. Buxboim et al.   JOURNAL OF CELL SCIENCE

How deeply cells feel: methods for thin gels

(2010) Amnon Buxboim et al.   JOURNAL OF PHYSICS-CONDENSED MATTER

Optimal matrix rigidity for stress-fibre polarization in stem cells

(2010) A. Zemel et al.   Nature Physics

Linear Arrays of Nuclear Envelope Proteins Harness Retrograde Actin Flow for Nuclear Movement

(2010) G. W. G. Luxton et al.   SCIENCE

Prestress and Adhesion Site Dynamics Control Cell Sensitivity to Extracellular Stiffness

(2009) S. Féréol et al.   BIOPHYSICAL JOURNAL

The Mechanical Rigidity of the Extracellular Matrix Regulates the Structure, Motility, and Proliferation of Glioma Cells

(2009) T. A. Ulrich et al.   CANCER RESEARCH

Matrix Strains Induced by Cells: Computing How Far Cells Can Feel

(2009) Shamik Sen et al.   Cellular and Molecular Bioengineering

The nuclear envelope—a scaffold for silencing?

(2009) Benjamin D Towbin et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Nuclei Take a Position: Managing Nuclear Location

(2009) Brian Burke et al.   DEVELOPMENTAL CELL

Nesprin 1 is critical for nuclear positioning and anchorage

(2009) Jianlin Zhang et al.   HUMAN MOLECULAR GENETICS

Nesprin 4 is an outer nuclear membrane protein that can induce kinesin-mediated cell polarization

(2009) K. J. Roux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A perinuclear actin cap regulates nuclear shape

(2009) Shyam B. Khatau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nonmuscle myosin II is responsible for maintaining endothelial cell basal tone and stress fiber integrity

(2008) Zoe M. Goeckeler et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Vascular endothelial responses to altered shear stress: Pathologic implications for atherosclerosis

(2008) Jeng-Jiann Chiu et al.   ANNALS OF MEDICINE

Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness

(2008) P.J. Stewart-Hutchinson et al.   EXPERIMENTAL CELL RESEARCH

Traction forces and rigidity sensing regulate cell functions

(2008) Marion Ghibaudo et al.   Soft Matter