Targeting T Cell Immunometabolism for Cancer Immunotherapy; Understanding the Impact of the Tumor Microenvironment
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Title
Targeting T Cell Immunometabolism for Cancer Immunotherapy; Understanding the Impact of the Tumor Microenvironment
Authors
Keywords
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Journal
Frontiers in Oncology
Volume 4, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2014-05-16
DOI
10.3389/fonc.2014.00107
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Note: Only part of the references are listed.- Sarcopenia, obesity, and natural killer cell immune senescence in aging: Altered cytokine levels as a common mechanism
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