MicroRNA in Human Glioma

NEDD9, a novel target of miR-145, increases the invasiveness of glioblastoma

(2015) Maria Carmela Speranza et al.   Oncotarget

Exosomes from marrow stromal cells expressing miR-146b inhibit glioma growth

(2013) Mark Katakowski et al.   CANCER LETTERS

Expression and clinical significance of microRNA-326 in human glioma miR-326 expression in glioma

(2013) Shuai Wang et al.   MEDICAL ONCOLOGY

MicroRNA-195 Inhibits the Proliferation of Human Glioma Cells by Directly Targeting Cyclin D1 and Cyclin E1

(2013) Wang Hui et al.   PLoS One

MicroRNA-145 Is Downregulated in Glial Tumors and Regulates Glioma Cell Migration by Targeting Connective Tissue Growth Factor

(2013) Hae Kyung Lee et al.   PLoS One

E2F1 promotes angiogenesis through the VEGF-C/VEGFR-3 axis in a feedback loop for cooperative induction of PDGF-B

(2013) David Engelmann et al.   Journal of Molecular Cell Biology

MiR-16-1 Plays a Role in Reducing Migration and Invasion of Glioma Cells

(2012) Xiangdong Li et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Over-expression of miR-145 enhances the effectiveness of HSVtk gene therapy for malignant glioma

(2012) Sang-Jin Lee et al.   CANCER LETTERS

MiR-15b and miR-152 reduce glioma cell invasion and angiogenesis via NRP-2 and MMP-3

(2012) Xuguang Zheng et al.   CANCER LETTERS

Loss of miR-204 Expression Enhances Glioma Migration and Stem Cell-like Phenotype

(2012) Z. Ying et al.   CANCER RESEARCH

miR-486 sustains NF-κB activity by disrupting multiple NF-κB-negative feedback loops

(2012) Libing Song et al.   CELL RESEARCH

MiR-21 Modulates hTERT Through a STAT3-Dependent Manner on Glioblastoma Cell Growth

(2012) Ying-Yi Wang et al.   CNS Neuroscience & Therapeutics

MicroRNA-21 Expression is regulated by β-catenin/STAT3 Pathway and Promotes Glioma Cell Invasion by Direct Targeting RECK

(2012) Lei Han et al.   CNS Neuroscience & Therapeutics

miR-137 is frequently down-regulated in glioblastoma and is a negative regulator of Cox-2

(2012) Lingchao Chen et al.   EUROPEAN JOURNAL OF CANCER

Myc-associated zinc finger protein (MAZ) is regulated by miR-125b and mediates VEGF-induced angiogenesis in glioblastoma

(2012) Michiel Smits et al.   FASEB JOURNAL

miR-125b regulates the proliferation of glioblastoma stem cells by targeting E2F2

(2012) Ning Wu et al.   FEBS LETTERS

PDGF-B-mediated downregulation of miR-21: new insights into PDGF signaling in glioblastoma

(2012) Pedro M. Costa et al.   HUMAN MOLECULAR GENETICS

MiR-410 regulates MET to influence the proliferation and invasion of glioma

(2012) Lingchao Chen et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Loss of Brain-enriched miR-124 MicroRNA Enhances Stem-like Traits and Invasiveness of Glioma Cells

(2012) Hongping Xia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased Expression of microRNA-17 Predicts Poor Prognosis in Human Glioma

(2012) Shengkui Lu et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

TGF-β induces miR-182 to sustain NF-κB activation in glioma subsets

(2012) Libing Song et al.   JOURNAL OF CLINICAL INVESTIGATION

MicroRNA-21 Inhibitor Sensitizes Human Glioblastoma U251 Stem Cells to Chemotherapeutic Drug Temozolomide

(2012) Shuguang Zhang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

High level of miR-221/222 confers increased cell invasion and poor prognosis in glioma

(2012) Chunzhi Zhang et al.   Journal of Translational Medicine

MicroRNA-195 plays a tumor-suppressor role in human glioblastoma cells by targeting signaling pathways involved in cellular proliferation and invasion

(2012) Qian-Qian Zhang et al.   NEURO-ONCOLOGY

VHL regulates the effects of miR-23b on glioma survival and invasion via suppression of HIF-1α/VEGF and β-catenin/Tcf-4 signaling

(2012) Lingchao Chen et al.   NEURO-ONCOLOGY

CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2005-2009

(2012) T. A. Dolecek et al.   NEURO-ONCOLOGY

Methylation mediated silencing of miR-23b expression and its role in glioma stem cells

(2012) Jiong Geng et al.   NEUROSCIENCE LETTERS

Effect of miR-21 and miR-30b/c on TRAIL-induced apoptosis in glioma cells

(2012) C Quintavalle et al.   ONCOGENE

MiR-145 reduces ADAM17 expression and inhibits in vitro migration and invasion of glioma cells

(2012) YONG LU et al.   ONCOLOGY REPORTS

MiR-218 reverses high invasiveness of glioblastoma cells by targeting the oncogenic transcription factor LEF1

(2012) YANWEI LIU et al.   ONCOLOGY REPORTS

MiR-128 Inhibits Tumor Growth and Angiogenesis by Targeting p70S6K1

(2012) Zhu-mei Shi et al.   PLoS One

Genome-Wide Profiling Identified a Set of miRNAs that Are Differentially Expressed in Glioblastoma Stem Cells and Normal Neural Stem Cells

(2012) Ming-Fei Lang et al.   PLoS One

miRNA Expression Profiling in Migrating Glioblastoma Cells: Regulation of Cell Migration and Invasion by miR-23b via Targeting of Pyk2

(2012) Joseph C. Loftus et al.   PLoS One

Silencing of MicroRNA-21 Confers Radio-Sensitivity through Inhibition of the PI3K/AKT Pathway and Enhancing Autophagy in Malignant Glioma Cell Lines

(2012) Ho-Shin Gwak et al.   PLoS One

Noise Propagation in Gene Regulation Networks Involving Interlinked Positive and Negative Feedback Loops

(2012) Hui Zhang et al.   PLoS One

cAMP response element-binding protein promotes gliomagenesis by modulating the expression of oncogenic microRNA-23a

(2012) X. Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-34a Suppresses Cell Proliferation and Induces Apoptosis in U87 Glioma Stem Cells

(2012) Lihua Sun et al.   TECHNOLOGY IN CANCER RESEARCH & TREATMENT

Ginsenoside Rh2 inhibits glioma cell proliferation by targeting microRNA-128

(2011) Nan Wu et al.   ACTA PHARMACOLOGICA SINICA

Molecular imaging of a cancer-targeting theragnostics probe using a nucleolin aptamer- and microRNA-221 molecular beacon-conjugated nanoparticle

(2011) Jin Kyeoung Kim et al.   BIOMATERIALS

MicroRNA-10b induces glioma cell invasion by modulating MMP-14 and uPAR expression via HOXD10

(2011) Lihua Sun et al.   BRAIN RESEARCH

A miR-21 inhibitor enhances apoptosis and reduces G2-M accumulation induced by ionizing radiation in human glioblastoma U251 cells

(2011) Yi Li et al.   Brain Tumor Pathology

Human Glioma Growth Is Controlled by MicroRNA-10b

(2011) G. Gabriely et al.   CANCER RESEARCH

The effect of miR-7 on behavior and global protein expression in glioma cell lines

(2011) Ze Jun Lu et al.   ELECTROPHORESIS

Chromatin-modifying drugs induce miRNA-153 expression to suppress Irs-2 in glioblastoma cell lines

(2011) Jianzhen Xu et al.   INTERNATIONAL JOURNAL OF CANCER

MicroRNA-30e* promotes human glioma cell invasiveness in an orthotopic xenotransplantation model by disrupting the NF-κB/IκBα negative feedback loop

(2011) Lili Jiang et al.   JOURNAL OF CLINICAL INVESTIGATION

Downregulation of Pdcd4 by mir-21 facilitates glioblastoma proliferation in vivo

(2011) A. B. Gaur et al.   NEURO-ONCOLOGY

NF-kB and c-Jun induce the expression of the oncogenic miR-221 and miR-222 in prostate carcinoma and glioblastoma cells

(2011) S. Galardi et al.   NUCLEIC ACIDS RESEARCH

Downregulation of Spry2 by miR-21 triggers malignancy in human gliomas

(2011) H-J Kwak et al.   ONCOGENE

miR-221/222 overexpession in human glioblastoma increases invasiveness by targeting the protein phosphate PTPμ

(2011) C Quintavalle et al.   ONCOGENE

Pro-neural miR-128 is a glioma tumor suppressor that targets mitogenic kinases

(2011) T Papagiannakopoulos et al.   ONCOGENE

MicroRNA and Target Protein Patterns Reveal Physiopathological Features of Glioma Subtypes

(2011) Elodie Lages et al.   PLoS One

Frequency Domain Analysis Reveals External Periodic Fluctuations Can Generate Sustained p53 Oscillation

(2011) Yong-Jun Shin et al.   PLoS One

Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma

(2011) J. D. Arroyo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

microRNA-7 increases radiosensitivity of human cancer cells with activated EGFR-associated signaling

(2011) Kyung Min Lee et al.   RADIOTHERAPY AND ONCOLOGY

miR-182 as a Prognostic Marker for Glioma Progression and Patient Survival

(2010) Lili Jiang et al.   AMERICAN JOURNAL OF PATHOLOGY

Regulation of mRNA Translation and Stability by microRNAs

(2010) Marc Robert Fabian et al.   Annual Review of Biochemistry

MicroRNA-21 inhibitor sensitizes human glioblastoma cells U251 (PTEN-mutant) and LN229 (PTEN-wild type) to taxol

(2010) Yu Ren et al.   BMC CANCER

MiRNA-451 plays a role as tumor suppressor in human glioma cells

(2010) Yang Nan et al.   BRAIN RESEARCH

MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity

(2010) Lei Shi et al.   BRAIN RESEARCH

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

MiR-146b-5p Suppresses EGFR Expression and ReducesIn VitroMigration and Invasion of Glioma

(2010) Mark Katakowski et al.   CANCER INVESTIGATION

miR-195, miR-455-3p and miR-10a∗ are implicated in acquired temozolomide resistance in glioblastoma multiforme cells

(2010) Kenta Ujifuku et al.   CANCER LETTERS

Direct Inhibition of Elastase Activity by Indole-3-Carbinol Triggers a CD40-TRAF Regulatory Cascade That Disrupts NF-κB Transcriptional Activity in Human Breast Cancer Cells

(2010) Ida Aronchik et al.   CANCER RESEARCH

let-7 and miR-17-92: Small-sized major players in lung cancer development

(2010) Hirotaka Osada et al.   CANCER SCIENCE

Survival of Patients with Newly Diagnosed Glioblastoma Treated with Radiation and Temozolomide in Research Studies in the United States

(2010) S. A. Grossman et al.   CLINICAL CANCER RESEARCH

Let-7 microRNA inhibits the proliferation of human glioblastoma cells

(2010) Soon-Tae Lee et al.   JOURNAL OF NEURO-ONCOLOGY

Downregulation of miR-21 inhibits EGFR pathway and suppresses the growth of human glioblastoma cells independent of PTEN status

(2010) Xuan Zhou et al.   LABORATORY INVESTIGATION

MiR-221 and miR-222 target PUMA to induce cell survival in glioblastoma

(2010) Chun-Zhi Zhang et al.   Molecular Cancer

MicroRNA-451 Regulates LKB1/AMPK Signaling and Allows Adaptation to Metabolic Stress in Glioma Cells

(2010) Jakub Godlewski et al.   MOLECULAR CELL

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

(2010) Mark E. Davis et al.   NATURE

Pyruvate kinase M2 is a target of the tumor-suppressive microRNA-326 and regulates the survival of glioma cells

(2010) B. Kefas et al.   NEURO-ONCOLOGY

De-repression of CTGF via the miR-17-92 cluster upon differentiation of human glioblastoma spheroid cultures

(2010) A Ernst et al.   ONCOGENE

Integrative genome analysis reveals an oncomir/oncogene cluster regulating glioblastoma survivorship

(2010) H. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Pathobiology of Glioma Tumors

(2009) Candece L. Gladson et al.   Annual Review of Pathology-Mechanisms of Disease

MicroRNA-15b regulates cell cycle progression by targeting cyclins in glioma cells

(2009) Hongping Xia et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identification and Functional Characterization of microRNAs Involved in the Malignant Progression of Gliomas

(2009) Bastian Malzkorn et al.   BRAIN PATHOLOGY

microRNA-146b inhibits glioma cell migration and invasion by targeting MMPs

(2009) Hongping Xia et al.   BRAIN RESEARCH

MicroRNA-21 targets LRRFIP1 and contributes to VM-26 resistance in glioblastoma multiforme

(2009) Yiming Li et al.   BRAIN RESEARCH

MiR-125b is critical for the suppression of human U251 glioma stem cell proliferation

(2009) Lei Shi et al.   BRAIN RESEARCH

miR-221&222 Regulate TRAIL Resistance and Enhance Tumorigenicity through PTEN and TIMP3 Downregulation

(2009) Michela Garofalo et al.   CANCER CELL

MicroRNA-34a Inhibits Glioblastoma Growth by Targeting Multiple Oncogenes

(2009) Y. Li et al.   CANCER RESEARCH

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Autocrine TGF-β Signaling Maintains Tumorigenicity of Glioma-Initiating Cells through Sry-Related HMG-Box Factors

(2009) Hiroaki Ikushima et al.   Cell Stem Cell

MiR-125b Expression Affects the Proliferation and Apoptosis of Human Glioma Cells by Targeting Bmf

(2009) Hong-Fei Xia et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Therapeutic strategies for inhibiting invasion in glioblastoma

(2009) Jan Drappatz et al.   Expert Review of Neurotherapeutics

The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo

(2009) J. T. Huse et al.   GENES & DEVELOPMENT

MicroRNA-10b is overexpressed in malignant glioma and associated with tumor invasive factors, uPAR and RhoC

(2009) Takashi Sasayama et al.   INTERNATIONAL JOURNAL OF CANCER

The Neuronal MicroRNA miR-326 Acts in a Feedback Loop with Notch and Has Therapeutic Potential against Brain Tumors

(2009) B. Kefas et al.   JOURNAL OF NEUROSCIENCE

The First Targeted Delivery of siRNA in Humans via a Self-Assembling, Cyclodextrin Polymer-Based Nanoparticle: From Concept to Clinic

(2009) Mark E. Davis   MOLECULAR PHARMACEUTICS

Small silencing RNAs: an expanding universe

(2009) Megha Ghildiyal et al.   NATURE REVIEWS GENETICS

Smart Magnetic Fluorescent Nanoparticle Imaging Probes to Monitor MicroRNAs

(2009) Do Won Hwang et al.   Small

MicroRNAs in Cancer

(2008) Yong Sun Lee et al.   Annual Review of Pathology-Mechanisms of Disease

miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells

(2008) Joachim Silber et al.   BMC Medicine

hsa-mir-181a and hsa-mir-181b function as tumor suppressors in human glioma cells

(2008) Lei Shi et al.   BRAIN RESEARCH

miR-296 Regulates Growth Factor Receptor Overexpression in Angiogenic Endothelial Cells

(2008) Thomas Würdinger et al.   CANCER CELL

MicroRNA-21 down-regulates the expression of tumor suppressor PDCD4 in human glioblastoma cell T98G

(2008) Yang Chen et al.   CANCER LETTERS

miR-34a inhibits migration and invasion by down-regulation of c-Met expression in human hepatocellular carcinoma cells

(2008) Na Li et al.   CANCER LETTERS

microRNA-7 Inhibits the Epidermal Growth Factor Receptor and the Akt Pathway and Is Down-regulated in Glioblastoma

(2008) B. Kefas et al.   CANCER RESEARCH

Targeting of the Bmi-1 Oncogene/Stem Cell Renewal Factor by MicroRNA-128 Inhibits Glioma Proliferation and Self-Renewal

(2008) J. Godlewski et al.   CANCER RESEARCH

MicroRNAs 221 and 222 Bypass Quiescence and Compromise Cell Survival

(2008) R. Medina et al.   CANCER RESEARCH

MicroRNA-21 Targets a Network of Key Tumor-Suppressive Pathways in Glioblastoma Cells

(2008) T. Papagiannakopoulos et al.   CANCER RESEARCH

Overlapping expression of microRNAs in human embryonic colon and colorectal cancer

(2008) Mariano Monzo et al.   CELL RESEARCH

Downregulation of CCND1 and CDK6 by miR-34a induces cell cycle arrest

(2008) Fang Sun et al.   FEBS LETTERS

MicroRNA-128 inhibits glioma cells proliferation by targeting transcription factor E2F3a

(2008) Yu Zhang et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

MicroRNA 21 Promotes Glioma Invasion by Targeting Matrix Metalloproteinase Regulators

(2008) G. Gabriely et al.   MOLECULAR AND CELLULAR BIOLOGY

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

(2008) Witold Filipowicz et al.   NATURE REVIEWS GENETICS

Malignant Gliomas in Adults

(2008) Patrick Y. Wen et al.   NEW ENGLAND JOURNAL OF MEDICINE

miR-17 and miR-20a temper an E2F1-induced G1 checkpoint to regulate cell cycle progression

(2008) M T Pickering et al.   ONCOGENE

MiR-221 controls CDKN1C/p57 and CDKN1B/p27 expression in human hepatocellular carcinoma

(2008) F Fornari et al.   ONCOGENE