Effect of miR-21 and miR-30b/c on TRAIL-induced apoptosis in glioma cells

Therapeutic effect of neural stem cells expressing TRAIL and bortezomib in mice with glioma xenografts

(2011) Irina V. Balyasnikova et al.   CANCER LETTERS

A Combined Array-Based Comparative Genomic Hybridization and Functional Library Screening Approach Identifies mir-30d As an Oncomir in Cancer

(2011) N. Li et al.   CANCER RESEARCH

MiR-195, miR-196b, miR-181c, miR-21 expression levels and O-6-methylguanine-DNA methyltransferase methylation status are associated with clinical outcome in glioblastoma patients

(2011) Radek Lakomy et al.   CANCER SCIENCE

Bortezomib Primes Glioblastoma, Including Glioblastoma Stem Cells, for TRAIL by Increasing tBid Stability and Mitochondrial Apoptosis

(2011) T. Unterkircher et al.   CLINICAL CANCER RESEARCH

miR221/222 in Cancer: Their Role in Tumor Progression and Response to Therapy

(2011) M. Garofalo et al.   CURRENT MOLECULAR MEDICINE

EGFR and MET receptor tyrosine kinase–altered microRNA expression induces tumorigenesis and gefitinib resistance in lung cancers

(2011) Michela Garofalo et al.   NATURE MEDICINE

Downregulation of Pdcd4 by mir-21 facilitates glioblastoma proliferation in vivo

(2011) A. B. Gaur et al.   NEURO-ONCOLOGY

Downregulation of Spry2 by miR-21 triggers malignancy in human gliomas

(2011) H-J Kwak et al.   ONCOGENE

A Phase 1b/2 trial of mapatumumab in patients with relapsed/refractory non-Hodgkin's lymphoma

(2010) A Younes et al.   BRITISH JOURNAL OF CANCER

Phase II trial of mapatumumab, a fully human agonistic monoclonal antibody that targets and activates the tumour necrosis factor apoptosis-inducing ligand receptor-1 (TRAIL-R1), in patients with refractory colorectal cancer

(2010) T Trarbach et al.   BRITISH JOURNAL OF CANCER

miR-212 Increases Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand Sensitivity in Non–Small Cell Lung Cancer by Targeting the Antiapoptotic Protein PED

(2010) Mariarosaria Incoronato et al.   CANCER RESEARCH

c-FLIPL enhances anti-apoptotic Akt functions by modulation of Gsk3β activity

(2010) C Quintavalle et al.   CELL DEATH AND DIFFERENTIATION

Targeting miR-21 in glioma: a small RNA with big potential

(2010) Lynette M Moore et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Survival comparison between glioblastoma multiforme and other incurable cancers

(2010) B. Tran et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Mir-30 reduction maintains self-renewal and inhibits apoptosis in breast tumor-initiating cells

(2010) F Yu et al.   ONCOGENE

New insights into apoptosis signaling by Apo2L/TRAIL

(2010) F Gonzalvez et al.   ONCOGENE

The miR-30 family microRNAs confer epithelial phenotype to human pancreatic cells

(2010) Mugdha V. Joglekar et al.   Islets

miR-30 Regulates Mitochondrial Fission through Targeting p53 and the Dynamin-Related Protein-1 Pathway

(2010) Jincheng Li et al.   PLoS Genetics

Identification and Functional Characterization of microRNAs Involved in the Malignant Progression of Gliomas

(2009) Bastian Malzkorn et al.   BRAIN PATHOLOGY

miR-221&222 Regulate TRAIL Resistance and Enhance Tumorigenicity through PTEN and TIMP3 Downregulation

(2009) Michela Garofalo et al.   CANCER CELL

MicroRNAs as regulators of death receptors signaling

(2009) M Garofalo et al.   CELL DEATH AND DIFFERENTIATION

Causes and consequences of microRNA dysregulation in cancer

(2009) Carlo M. Croce   NATURE REVIEWS GENETICS

Advances in the genetics of glioblastoma: are we reaching critical mass?

(2009) Benjamin Purow et al.   Nature Reviews Neurology

MicroRNA-21 Targets a Network of Key Tumor-Suppressive Pathways in Glioblastoma Cells

(2008) T. Papagiannakopoulos et al.   CANCER RESEARCH

MicroRNAs in diseases and drug response

(2008) M GAROFALO et al.   CURRENT OPINION IN PHARMACOLOGY

PED is overexpressed and mediates TRAIL resistance in human non-small cell lung cancer

(2008) Ciro Zanca et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

MicroRNA 21 Promotes Glioma Invasion by Targeting Matrix Metalloproteinase Regulators

(2008) G. Gabriely et al.   MOLECULAR AND CELLULAR BIOLOGY

MicroRNA signatures of TRAIL resistance in human non-small cell lung cancer

(2008) M Garofalo et al.   ONCOGENE