Nutritional systems biology of type 2 diabetes

Impairment of Wound Healing in Patients With Type 2 Diabetes Mellitus Influences Circulating MicroRNA Patterns via Inflammatory Cytokines

(2015) S. Dangwal et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Circadian systems biology in Metazoa

(2015) L.-L. Lin et al.   BRIEFINGS IN BIOINFORMATICS

Modulation of the faecal microbiome of healthy adult dogs by inclusion of potato fibre in the diet

(2015) Matthew R. Panasevich et al.   BRITISH JOURNAL OF NUTRITION

Genetic Architecture of Insulin Resistance in the Mouse

(2015) Brian W. Parks et al.   Cell Metabolism

Metabolomics as a tool in nutritional research

(2015) Helena Gibbons et al.   CURRENT OPINION IN LIPIDOLOGY

High fat, high sucrose diet causes cardiac mitochondrial dysfunction due in part to oxidative post-translational modification of mitochondrial complex II

(2015) Aaron L. Sverdlov et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome

(2015) Benoit Chassaing et al.   NATURE

Long non-coding RNAs as regulators of the endocrine system

(2015) Marko Knoll et al.   Nature Reviews Endocrinology

RNA-mediated epigenetic regulation of gene expression

(2015) Daniel Holoch et al.   NATURE REVIEWS GENETICS

Nutriproteomics: Facts, concepts, and perspectives

(2015) Sascha Sauer et al.   PROTEOMICS

The Emerging Role of microRNAs and Nutrition in Modulating Health and Disease

(2014) Sharon A. Ross et al.   Annual Review of Nutrition

Beneficial effects of soluble dietary Jerusalem artichoke (Helianthus tuberosus) in the prevention of the onset of type 2 diabetes and non-alcoholic fatty liver disease in high-fructose diet-fed rats

(2014) Wan-Ching Chang et al.   BRITISH JOURNAL OF NUTRITION

Multilayered Genetic and Omics Dissection of Mitochondrial Activity in a Mouse Reference Population

(2014) Yibo Wu et al.   CELL

The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones

(2014) Thomas R. Cech et al.   CELL

Insights Into the Role of the Microbiome in Obesity and Type 2 Diabetes

(2014) Annick V. Hartstra et al.   DIABETES CARE

Discovery of Molecular Pathways Mediating 1,25-Dihydroxyvitamin D3Protection Against Cytokine-Induced Inflammation and Damage of Human and Male Mouse Islets of Langerhans

(2014) H. Wolden-Kirk et al.   ENDOCRINOLOGY

Sexual Dimorphism in Offspring Glucose-Sensitive Hypothalamic Gene Expression and Physiological Responses to Maternal High-Fat Diet Feeding

(2014) Laura Dearden et al.   ENDOCRINOLOGY

Paternal high-fat diet consumption induces common changes in the transcriptomes of retroperitoneal adipose and pancreatic islet tissues in female rat offspring

(2014) Sheau-Fang Ng et al.   FASEB JOURNAL

Diet and the Intestinal Microbiome: Associations, Functions, and Implications for Health and Disease

(2014) Lindsey G. Albenberg et al.   GASTROENTEROLOGY

Distinct signatures of host–microbial meta-metabolome and gut microbiome in two C57BL/6 strains under high-fat diet

(2014) Alesia Walker et al.   ISME Journal

Open Chromatin Profiling in Mice Livers Reveals Unique Chromatin Variations Induced by High Fat Diet

(2014) Amy Leung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Maternal Overnutrition Programs Changes in the Expression of Skeletal Muscle Genes That Are Associated with Insulin Resistance and Defects of Oxidative Phosphorylation in Adult Male Rat Offspring

(2014) Celine Latouche et al.   JOURNAL OF NUTRITION

A draft map of the human proteome

(2014) Min-Sik Kim et al.   NATURE

Artificial sweeteners induce glucose intolerance by altering the gut microbiota

(2014) Jotham Suez et al.   NATURE

The emergence of proteome-wide technologies: systematic analysis of proteins comes of age

(2014) Michal Breker et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Microarray Analysis of Rat Pancreas Reveals Altered Expression of Alox15 and Regenerating Islet-Derived Genes in Response to Iron Deficiency and Overload

(2014) Richard Coffey et al.   PLoS One

Alterations of Pancreatic Islet Structure, Metabolism and Gene Expression in Diet-Induced Obese C57BL/6J Mice

(2014) Regan Roat et al.   PLoS One

Transcriptome Analysis on the Inflammatory Cell Infiltration of Nonalcoholic Steatohepatitis in Bama Minipigs Induced by a Long-Term High-Fat, High-Sucrose Diet

(2014) Jihan Xia et al.   PLoS One

Defining a personal, allele-specific, and single-molecule long-read transcriptome

(2014) Hagen Tilgner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vitamin D Status Affects Serum Metabolomic Profiles in Pregnant Adolescents

(2014) Julia L. Finkelstein et al.   Reproductive Sciences

High-fat maternal diet during pregnancy persistently alters the offspring microbiome in a primate model

(2014) Jun Ma et al.   Nature Communications

Genome-Wide Associations between Genetic and Epigenetic Variation Influence mRNA Expression and Insulin Secretion in Human Pancreatic Islets

(2014) Anders H. Olsson et al.   PLoS Genetics

Circadian control of glucose metabolism

(2014) Andries Kalsbeek et al.   Molecular Metabolism

Regulation of metabolism by long, non-coding RNAs

(2014) Jan-Wilhelm Kornfeld et al.   Frontiers in Genetics

Divergent compensatory responses to high-fat diet between C57BL6/J and C57BLKS/J inbred mouse strains

(2013) Emily K. Sims et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Reprogramming of the Circadian Clock by Nutritional Challenge

(2013) Kristin L. Eckel-Mahan et al.   CELL

Mapping Human Epigenomes

(2013) Chloe M. Rivera et al.   CELL

Genetic Control of Obesity and Gut Microbiota Composition in Response to High-Fat, High-Sucrose Diet in Mice

(2013) Brian W. Parks et al.   Cell Metabolism

Nupr1 deletion protects against glucose intolerance by increasing beta cell mass

(2013) Helena C. Barbosa-Sampaio et al.   DIABETOLOGIA

Maternal obesity and diabetes induces latent metabolic defects and widespread epigenetic changes in isogenic mice

(2013) Cheryl C.Y. Li et al.   Epigenetics

Epigenetics meets metabolomics: an epigenome-wide association study with blood serum metabolic traits

(2013) Ann-Kristin Petersen et al.   HUMAN MOLECULAR GENETICS

DNA hypomethylation of inflammation-associated genes in adipose tissue of female mice after multigenerational high fat diet feeding

(2013) Y Ding et al.   INTERNATIONAL JOURNAL OF OBESITY

Parental Dietary Fat Intake Alters Offspring Microbiome and Immunity

(2013) I. A. Myles et al.   JOURNAL OF IMMUNOLOGY

High throughput sequencing methods and analysis for microbiome research

(2013) Julia M. Di Bella et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Metabolite Profile Analysis Reveals Functional Effects of 28-Day Vitamin B-6 Restriction on One-Carbon Metabolism and Tryptophan Catabolic Pathways in Healthy Men and Women

(2013) Vanessa R. da Silva et al.   JOURNAL OF NUTRITION

Current practice of liquid chromatography–mass spectrometry in metabolomics and metabonomics

(2013) Helen G. Gika et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Early Diet Impacts Infant Rhesus Gut Microbiome, Immunity, and Metabolism

(2013) Aifric O’Sullivan et al.   JOURNAL OF PROTEOME RESEARCH

PPAR signaling pathway is a key modulator of liver proteome in pups born to vitamin B12 deficient rats

(2013) Shadab Ahmad et al.   Journal of Proteomics

Quantitative Proteomic and Functional Analysis of Liver Mitochondria from High Fat Diet (HFD) Diabetic Mice

(2013) Yurong Guo et al.   MOLECULAR & CELLULAR PROTEOMICS

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

Global burden of disease—where does diabetes mellitus fit in?

(2013) K. George M. M. Alberti et al.   Nature Reviews Endocrinology

“Seq-ing” Insights into the Epigenetics of Neuronal Gene Regulation

(2013) Francesca Telese et al.   NEURON

The miRNA Profile of Human Pancreatic Islets and Beta-Cells and Relationship to Type 2 Diabetes Pathogenesis

(2013) Martijn van de Bunt et al.   PLoS One

MiR-155 Has a Protective Role in the Development of Non-Alcoholic Hepatosteatosis in Mice

(2013) Ashley M. Miller et al.   PLoS One

Nutrigenomics of High Fat Diet Induced Obesity in Mice Suggests Relationships between Susceptibility to Fatty Liver Disease and the Proteasome

(2013) Helen Waller-Evans et al.   PLoS One

Low paternal dietary folate alters the mouse sperm epigenome and is associated with negative pregnancy outcomes

(2013) R. Lambrot et al.   Nature Communications

Nutritional Epigenomics: A Portal to Disease Prevention

(2013) Sang-Woon Choi et al.   Advances in Nutrition

Mechanisms of Inflammatory Responses in Obese Adipose Tissue

(2012) Shengyi Sun et al.   Annual Review of Nutrition

Unconventional microarray design reveals the response to obesity is largely tissue specific: analysis of common and divergent responses to diet-induced obesity in insulin-sensitive tissues

(2012) Robyn K. Lee et al.   Applied Physiology Nutrition and Metabolism

A low protein diet during pregnancy provokes a lasting shift of hepatic expression of genes related to cell cycle throughout ontogenesis in a porcine model

(2012) Michael Oster et al.   BMC GENOMICS

A whole-body mathematical model of cholesterol metabolism and its age-associated dysregulation

(2012) Mark T Mc Auley et al.   BMC Systems Biology

Personal Omics Profiling Reveals Dynamic Molecular and Medical Phenotypes

(2012) Rui Chen et al.   CELL

High Fat Diet Differentially Regulates the Expression of Olfactory Receptors in the Duodenum of Obesity-Prone and Obesity-Resistant Rats

(2012) Stefany D. Primeaux et al.   DIGESTIVE DISEASES AND SCIENCES

DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients

(2012) Michael Volkmar et al.   EMBO JOURNAL

Analysis of hepatic gene expression profile in a spontaneous mouse model of type 2 diabetes under a high sucrose diet

(2012) Koji Nojima et al.   ENDOCRINE JOURNAL

Transfer of Intestinal Microbiota From Lean Donors Increases Insulin Sensitivity in Individuals With Metabolic Syndrome

(2012) Anne Vrieze et al.   GASTROENTEROLOGY

Foodomics: a new comprehensive approach to food and nutrition

(2012) Francesco Capozzi et al.   Genes and Nutrition

Higher dietary fructose is associated with impaired hepatic adenosine triphosphate homeostasis in obese individuals with type 2 diabetes

(2012) Manal F. Abdelmalek et al.   HEPATOLOGY

Network analysis of adipose tissue gene expression highlights altered metabolic and regulatory transcriptomic activity in high-fat-diet-fed IL-1RI knockout mice

(2012) Melissa J. Morine et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Unraveling the effects of 1,25(OH)2D3 on global gene expression in pancreatic islets

(2012) H. Wolden-Kirk et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits

(2012) Anatole Ghazalpour et al.   MAMMALIAN GENOME

DNA microarray analysis reveals differential gene expression in the soleus muscle between male and female rats exposed to a high fat diet

(2012) Tae Seok Oh et al.   MOLECULAR BIOLOGY REPORTS

A metagenome-wide association study of gut microbiota in type 2 diabetes

(2012) Junjie Qin et al.   NATURE

DNA methylation profiling in the clinic: applications and challenges

(2012) Holger Heyn et al.   NATURE REVIEWS GENETICS

MicroRNA profiling: approaches and considerations

(2012) Colin C. Pritchard et al.   NATURE REVIEWS GENETICS

High Fat Diet-Induced Gut Microbiota Exacerbates Inflammation and Obesity in Mice via the TLR4 Signaling Pathway

(2012) Kyung-Ah Kim et al.   PLoS One

Assessment of the Effect of High or Low Protein Diet on the Human Urine Metabolome as Measured by NMR

(2012) Lone G. Rasmussen et al.   Nutrients

Reconstruction and analysis of human heart-specific metabolic network based on transcriptome and proteome data

(2011) Yuqi Zhao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Globalization of Diabetes: The role of diet, lifestyle, and genes

(2011) F. B. Hu   DIABETES CARE

The False-positive to False-negative Ratio in Epidemiologic Studies

(2011) John P. A. Ioannidis et al.   EPIDEMIOLOGY

Lifestyle and Genetics in Obesity and type 2 Diabetes

(2011) T. Temelkova-Kurktschiev et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

MicroRNA regulation in mammalian adipogenesis

(2011) Josue M Romao et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Using the reconstructed genome-scale human metabolic network to study physiology and pathology

(2011) A. Bordbar et al.   JOURNAL OF INTERNAL MEDICINE

Nutrient excess and altered mitochondrial proteome and function contribute to neurodegeneration in diabetes

(2011) Subir K. Roy Chowdhury et al.   MITOCHONDRION

Beyond glucose: metabolic shifts in responses to the effects of the oral glucose tolerance test and the high-fructose diet in rats

(2011) Shuhai Lin et al.   Molecular BioSystems

Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling

(2011) Haitao Wen et al.   NATURE IMMUNOLOGY

Metabolite profiles and the risk of developing diabetes

(2011) Thomas J Wang et al.   NATURE MEDICINE

The worldwide epidemiology of type 2 diabetes mellitus—present and future perspectives

(2011) Lei Chen et al.   Nature Reviews Endocrinology

Linking Long-Term Dietary Patterns with Gut Microbial Enterotypes

(2011) G. D. Wu et al.   SCIENCE

Diminished Superoxide Generation Is Associated With Respiratory Chain Dysfunction and Changes in the Mitochondrial Proteome of Sensory Neurons From Diabetic Rats

(2010) E. Akude et al.   DIABETES

A high-resolution association mapping panel for the dissection of complex traits in mice

(2010) B. J. Bennett et al.   GENOME RESEARCH

An 8-Week High-Fat Diet Induces Obesity and Insulin Resistance with Small Changes in the Muscle Transcriptome of C57BL/6J Mice

(2010) Janneke de Wilde et al.   Journal of Nutrigenetics and Nutrigenomics

Metabolomic Analysis of Livers and Serum from High-Fat Diet Induced Obese Mice

(2010) Hyun-Jin Kim et al.   JOURNAL OF PROTEOME RESEARCH

RNA sequencing: advances, challenges and opportunities

(2010) Fatih Ozsolak et al.   NATURE REVIEWS GENETICS

Principles and challenges of genome-wide DNA methylation analysis

(2010) Peter W. Laird   NATURE REVIEWS GENETICS

Diabetic kidney disease: act now or pay later

(2010) Robert C. Atkins et al.   Nature Reviews Nephrology

Gut Microbiota in Human Adults with Type 2 Diabetes Differs from Non-Diabetic Adults

(2010) Nadja Larsen et al.   PLoS One

Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa

(2010) C. De Filippo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nutritional Systems Biology: Definitions and Approaches

(2009) Gianni Panagiotou et al.   Annual Review of Nutrition

Lipoic acid attenuates high fat diet-induced chronic oxidative stress and immunosuppression in mice jejunum: A microarray analysis

(2009) Jue Cui et al.   CELLULAR IMMUNOLOGY

Butyrate Improves Insulin Sensitivity and Increases Energy Expenditure in Mice

(2009) Z. Gao et al.   DIABETES

Ketohexokinase-Dependent Metabolism of Fructose Induces Proinflammatory Mediators in Proximal Tubular Cells

(2009) P. Cirillo et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Proteome, Phosphoproteome, and Hydroxyproteome of Liver Mitochondria in Diabetic Rats at Early Pathogenic Stages

(2009) Wen-Jun Deng et al.   MOLECULAR & CELLULAR PROTEOMICS

Epigenetic mechanisms that underpin metabolic and cardiovascular diseases

(2009) Peter D. Gluckman et al.   Nature Reviews Endocrinology

Effect of high-fat feeding on expression of genes controlling availability of dopamine in mouse hypothalamus

(2009) Alex K. Lee et al.   NUTRITION

Nutritional Systems Biology Modeling: From Molecular Mechanisms to Physiology

(2009) Albert A. de Graaf et al.   PLoS Computational Biology

Applications of next-generation sequencing technologies in functional genomics

(2008) Olena Morozova et al.   GENOMICS

Proteomic analysis of fructose-induced fatty liver in hamsters

(2008) Lihe Zhang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Proteomics in diabetes research

(2008) T SUNDSTEN et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

RNA-Seq: a revolutionary tool for transcriptomics

(2008) Zhong Wang et al.   NATURE REVIEWS GENETICS

Obesity Upregulates Genes Involved in Oxidative Phosphorylation in Livers of Diabetic Patients

(2008) Toshinari Takamura et al.   Obesity

Nutritional Deficiencies in Morbidly Obese Patients: A New Form of Malnutrition?

(2008) Orit Kaidar-Person et al.   OBESITY SURGERY

Nutritional Deficiencies in Morbidly Obese Patients: A New Form of Malnutrition?

(2008) Orit Kaidar-Person et al.   OBESITY SURGERY

Real-Time DNA Sequencing from Single Polymerase Molecules

(2008) J. Eid et al.   SCIENCE