Sorbitol treatment extends lifespan and induces the osmotic stress response in Caenorhabditis elegans

A Platform for Rapid Exploration of Aging and Diseases in a Naturally Short-Lived Vertebrate

(2015) Itamar Harel et al.   CELL

Why Is Aging Conserved and What Can We Do about It?

(2015) Jason N. Pitt et al.   PLOS BIOLOGY

Caloric restriction reduces age-related and all-cause mortality in rhesus monkeys

(2014) Ricki J. Colman et al.   Nature Communications

Molecular mechanisms underlying genotype-dependent responses to dietary restriction

(2013) Jennifer Schleit et al.   AGING CELL

Life-Span Extension From Hypoxia in Caenorhabditis elegans Requires Both HIF-1 and DAF-16 and Is Antagonized by SKN-1

(2013) Scott F. Leiser et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

mTOR is a key modulator of ageing and age-related disease

(2013) Simon C. Johnson et al.   NATURE

Genome-Wide RNAi Longevity Screens in Caenorhabditis elegans

(2012) Melana E. Yanos et al.   CURRENT GENOMICS

Response to Hyperosmotic Stress

(2012) H. Saito et al.   GENETICS

Dietary restriction in rats and mice: A meta-analysis and review of the evidence for genotype-dependent effects on lifespan

(2011) William R. Swindell   AGEING RESEARCH REVIEWS

Sir2 deletion prevents lifespan extension in 32 long-lived mutants

(2011) Joe R. Delaney et al.   AGING CELL

HIF-1 modulates longevity and healthspan in a temperature-dependent manner

(2011) Scott F. Leiser et al.   AGING CELL

The hypoxic response and aging

(2011) Matt Kaeberlein et al.   CELL CYCLE

Calorie restriction and prevention of age-associated chronic disease

(2011) Daniela Omodei et al.   FEBS LETTERS

A Method for High-Throughput Quantitative Analysis of Yeast Chronological Life Span

(2011) C. J. Murakami et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Regulation of Caenorhabditis elegans lifespan by sir-2.1 transgenes

(2011) Mohan Viswanathan et al.   NATURE

Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila

(2011) Camilla Burnett et al.   NATURE

Trehalose extends longevity in the nematode Caenorhabditis elegans

(2010) Yoko Honda et al.   AGING CELL

The hypoxia-inducible factor HIF-1 functions as both a positive and negative modulator of aging

(2010) Scott F. Leiser et al.   BIOLOGICAL CHEMISTRY

A molecular mechanism of chronological aging in yeast

(2010) Christopher R. Burtner et al.   CELL CYCLE

With TOR, Less Is More: A Key Role for the Conserved Nutrient-Sensing TOR Pathway in Aging

(2010) Pankaj Kapahi et al.   Cell Metabolism

Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice

(2010) Richard A. Miller et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Lessons on longevity from budding yeast

(2010) Matt Kaeberlein   NATURE

The genetics of ageing

(2010) Cynthia J. Kenyon   NATURE

Extending Healthy Life Span--From Yeast to Humans

(2010) L. Fontana et al.   SCIENCE

Genetic variation in the murine lifespan response to dietary restriction: from life extension to life shortening

(2009) Chen-Yu Liao et al.   AGING CELL

A High-Throughput Screen for Chemicals that Increase the Lifespan of Caenorhabditis elegans

(2009) Michael Petrascheck et al.   Annals of the New York Academy of Sciences

The von Hippel Lindau Tumor Suppressor Limits Longevity

(2009) R.-U. Muller et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Hydrogen Sulfide Increases Hypoxia-inducible Factor-1 Activity Independently of von Hippel–Lindau Tumor Suppressor-1 in C. elegans

(2009) Mark W. Budde et al.   MOLECULAR BIOLOGY OF THE CELL

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

(2009) David E. Harrison et al.   NATURE

The HIF-1 Hypoxia-Inducible Factor Modulates Lifespan in C. elegans

(2009) Yi Zhang et al.   PLoS One

Proteasomal Regulation of the Hypoxic Response Modulates Aging in C. elegans

(2009) R. Mehta et al.   SCIENCE

Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span

(2009) C. Selman et al.   SCIENCE

Measuring Caenorhabditis elegans Life Span on Solid Media

(2009) George L. Sutphin et al.   Jove-Journal of Visualized Experiments

Design of aging intervention studies: the NIA interventions testing program

(2008) N. L. Nadon et al.   AGE

Genome-wide RNAi screen and in vivo protein aggregation reporters identify degradation of damaged proteins as an essential hypertonic stress response

(2008) Keith P. Choe et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Age- and calorie-independent life span extension from dietary restriction by bacterial deprivation in Caenorhabditis elegans

(2008) Erica D Smith et al.   BMC DEVELOPMENTAL BIOLOGY

Dietary restriction by bacterial deprivation increases life span in wild-derived nematodes

(2007) George L. Sutphin et al.   EXPERIMENTAL GERONTOLOGY