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Title
Heat shock proteins in neurodegenerative disorders and aging
Authors
Keywords
Chaperone, Vitagene, Proteostasis, Ageing, Aging, Adaptation, Hormesis
Journal
Journal of Cell Communication and Signaling
Volume 8, Issue 4, Pages 293-310
Publisher
Springer Nature
Online
2014-09-10
DOI
10.1007/s12079-014-0243-9
References
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Note: Only part of the references are listed.- Impact of aging on heat shock protein expression in the substantia nigra and striatum of the female rat
- (2014) A. M. Gleixner et al. CELL AND TISSUE RESEARCH
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- (2014) Donna Kennedy et al. IUBMB LIFE
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- Policy: NIH to balance sex in cell and animal studies
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- The Hallmarks of Aging
- (2013) Carlos López-Otín et al. CELL
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- (2013) Amanda M. Titler et al. CELL AND TISSUE RESEARCH
- Overexpression of Hsp27 ameliorates symptoms of Alzheimer's disease in APP/PS1 mice
- (2013) Melinda Erzsébet Tóth et al. CELL STRESS & CHAPERONES
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- (2013) Ajay S. Unnithan et al. NEUROSCIENCE LETTERS
- Neocortex and Allocortex Respond Differentially to Cellular Stress In Vitro and Aging In Vivo
- (2013) Jessica M. Posimo et al. PLoS One
- Neurotoxicity of Amyloid -Protein: Synaptic and Network Dysfunction
- (2013) L. Mucke et al. Cold Spring Harbor Perspectives in Medicine
- Stress responses, vitagenes and hormesis as critical determinants in aging and longevity: Mitochondria as a “chi”
- (2013) Carolin Cornelius et al. Immunity & Ageing
- The G2385R variant of leucine-rich repeat kinase 2 associated with Parkinson's disease is a partial loss-of-function mutation
- (2012) Iakov N. Rudenko et al. BIOCHEMICAL JOURNAL
- Molecular Chaperones as Rational Drug Targets for Parkinsons Disease Therapeutics
- (2012) S. K. Kalia et al. CNS & Neurological Disorders-Drug Targets
- Autophagy in the Central Nervous System: Implications for Neurodegenerative Disorders
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- Small heat shock proteins HSP27 (HspB1), αB-crystallin (HspB5) and HSP22 (HspB8) as regulators of cell death
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- Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice
- (2012) Kelvin C. Luk et al. JOURNAL OF EXPERIMENTAL MEDICINE
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- (2012) E.-J. Bae et al. JOURNAL OF NEUROSCIENCE
- Endoplasmic Reticulum Enrollment in Alzheimer’s Disease
- (2012) Ricardo J. S. Viana et al. MOLECULAR NEUROBIOLOGY
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- (2012) Leonid Molochnikov et al. Molecular Neurodegeneration
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- (2012) Marina S Gorbatyuk et al. MOLECULAR THERAPY
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- (2012) Meijuan Zhang et al. PROGRESS IN NEUROBIOLOGY
- Pathological -Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
- (2012) K. C. Luk et al. SCIENCE
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- (2012) Erin K. Butler et al. PLoS Genetics
- Cellular stress responses, hormetic phytochemicals and vitagenes in aging and longevity
- (2011) Vittorio Calabrese et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
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- (2010) Antero Salminen et al. PROGRESS IN NEUROBIOLOGY
- Chaperone-mediated autophagy: Molecular mechanisms and physiological relevance
- (2010) Samantha J. Orenstein et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Integration of Clearance Mechanisms: The Proteasome and Autophagy
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- (2009) Cintia Roodveldt et al. EMBO JOURNAL
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- Recent advances in our understanding of neurodegeneration
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- (2009) Karin M. Danzer et al. JOURNAL OF NEUROCHEMISTRY
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- (2009) Xiaodong Ding et al. PLoS One
- Inclusion formation and neuronal cell death through neuron-to-neuron transmission of -synuclein
- (2009) P. Desplats et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2009) Han Seok Ko et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2009) Heather A. Boger et al. PROGRESS IN NEUROBIOLOGY
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- (2008) Chad Dickey et al. AMERICAN JOURNAL OF PATHOLOGY
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