Cellular Stress Responses, The Hormesis Paradigm, and Vitagenes: Novel Targets for Therapeutic Intervention in Neurodegenerative Disorders

The Transcription Factor Nrf2 Is a Therapeutic Target against Brain Inflammation

(2014) N. G. Innamorato et al.   JOURNAL OF IMMUNOLOGY

Preventing NAD+ Depletion Protects Neurons against Excitotoxicity

(2010) Dong Liu et al.   Annals of the New York Academy of Sciences

The Nrf2-ARE Pathway

(2010) Jeffrey A. Johnson et al.   Annals of the New York Academy of Sciences

Ferulic Acid Protects Human Umbilical Vein Endothelial Cells from Radiation Induced Oxidative Stress by Phosphatidylinositol 3-Kinase and Extracellular Signal-Regulated Kinase Pathways

(2010) Zeng-Chun Ma et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

A cellular perspective on conformational disease: the role of genetic background and proteostasis networks

(2010) Tali Gidalevitz et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

AIRAP, a New Human Heat Shock Gene Regulated by Heat Shock Factor 1

(2010) Antonio Rossi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Overexpression of Heme Oxygenase-1 Is Neuroprotective in a Model of Permanent Middle Cerebral Artery Occlusion in Transgenic Mice

(2010) Nariman Panahian et al.   JOURNAL OF NEUROCHEMISTRY

ER and aging—Protein folding and the ER stress response

(2009) Nirinjini Naidoo   AGEING RESEARCH REVIEWS

Dynamic regulation of PGC-1α localization and turnover implicates mitochondrial adaptation in calorie restriction and the stress response

(2009) Rozalyn M. Anderson et al.   AGING CELL

Age and energy intake interact to modify cell stress pathways and stroke outcome

(2009) Thiruma V. Arumugam et al.   ANNALS OF NEUROLOGY

Gene Expression Profiling Related to Anti-inflammatory Properties of Curcumin in K562 Leukemia Cells

(2009) Marie-Helene Teiten et al.   Annals of the New York Academy of Sciences

Nitric Oxide in Cell Survival: A Janus Molecule

(2009) Vittorio Calabrese et al.   ANTIOXIDANTS & REDOX SIGNALING

Carnosinase Levels in Aging Brain: Redox State Induction and Cellular Stress Response

(2009) Francesco Bellia et al.   ANTIOXIDANTS & REDOX SIGNALING

Novel Insights Into Hydrogen Sulfide–Mediated Cytoprotection

(2009) John W. Calvert et al.   ANTIOXIDANTS & REDOX SIGNALING

Nitric oxide and pathogenic mechanisms involved in the development of vascular diseases

(2009) Claudio Napoli et al.   ARCHIVES OF PHARMACAL RESEARCH

Getting the dose–response wrong: why hormesis became marginalized and the threshold model accepted

(2009) Edward J. Calabrese   ARCHIVES OF TOXICOLOGY

The road to linearity: why linearity at low doses became the basis for carcinogen risk assessment

(2009) Edward J. Calabrese   ARCHIVES OF TOXICOLOGY

RETRACTED: Design of curcumin-loaded PLGA nanoparticles formulation with enhanced cellular uptake, and increased bioactivity in vitro and superior bioavailability in vivo

(2009) Preetha Anand et al.   BIOCHEMICAL PHARMACOLOGY

Inhibitors of protein aggregation and toxicity

(2009) Hozefa Amijee et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Vitagenes, cellular stress response, and acetylcarnitine: Relevance to hormesis

(2009) Vittorio Calabrese et al.   BIOFACTORS

Interplay between protein homeostasis networks in protein aggregation and proteotoxicity

(2009) Peter M. Douglas et al.   BIOPOLYMERS

Genetic versus chemoprotective activation of Nrf2 signaling: overlapping yet distinct gene expression profiles between Keap1 knockout and triterpenoid-treated mice

(2009) Melinda S. Yates et al.   CARCINOGENESIS

Resveratrol is Not a Direct Activator of SIRT1 Enzyme Activity

(2009) Dirk Beher et al.   Chemical Biology & Drug Design

Hydrogen Sulfide Mediates Cardioprotection Through Nrf2 Signaling

(2009) John W. Calvert et al.   CIRCULATION RESEARCH

Age-Accelerated Atherosclerosis Correlates With Failure to Upregulate Antioxidant Genes

(2009) Alan R. Collins et al.   CIRCULATION RESEARCH

Pain and U-Shaped Dose Responses: Occurrence, Mechanisms, and Clinical Implications

(2009) Edward J. Calabrese   CRITICAL REVIEWS IN TOXICOLOGY

U-Shaped Dose Response in Behavioral Pharmacology: Historical Foundations

(2009) Edward J. Calabrese   CRITICAL REVIEWS IN TOXICOLOGY

Addiction and Dose Response: The Psychomotor Stimulant Theory of Addiction Reveals That Hormetic Dose Responses Are Dominant

(2009) Edward J. Calabrese   CRITICAL REVIEWS IN TOXICOLOGY

Awareness of Hormesis Will Enhance Future Research in Basic and Applied Neuroscience

(2009) Mark P. Mattson   CRITICAL REVIEWS IN TOXICOLOGY

Disaggregating Chaperones: An Unfolding Story

(2009) Sandeep Sharma et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Effects of carbon monoxide releasing molecule-liberated CO on severe acute pancreatitis in rats

(2009) Ping Chen et al.   CYTOKINE

A Perspective on the Scientific, Philosophical, and Policy Dimensions of Hormesis

(2009) George R. Hoffmann   Dose-Response

ER stress protects from retinal degeneration

(2009) César S Mendes et al.   EMBO JOURNAL

SIRT2-mediated protein deacetylation: An emerging key regulator in brain physiology and pathology

(2009) Kai Harting et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

The role of molecular chaperones in human misfolding diseases

(2009) Sarah A. Broadley et al.   FEBS LETTERS

Vitagenes, dietary antioxidants and neuroprotection in neurodegenerative diseases

(2009) Vittorio Calabrese   Frontiers in Bioscience-Landmark

The Shock of Aging: Molecular Chaperones and the Heat Shock Response in Longevity and Aging – A Mini-Review

(2009) Stuart K. Calderwood et al.   GERONTOLOGY

Curcumin Modulates the Radiosensitivity of Colorectal Cancer Cells by Suppressing Constitutive and Inducible NF-κB Activity

(2009) Santosh K. Sandur et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Vascular Endothelium Expresses 3-Mercaptopyruvate Sulfurtransferase and Produces Hydrogen Sulfide

(2009) N. Shibuya et al.   JOURNAL OF BIOCHEMISTRY

PGC-1α and PGC-1β Regulate Mitochondrial Density in Neurons

(2009) Przemyslaw Wareski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Nrf2-Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress

(2009) Truyen Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

S-Nitrosylation of Cardiac Ion Channels

(2009) Daniel R Gonzalez et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Measurement and biological significance of the volatile sulfur compounds hydrogen sulfide, methanethiol and dimethyl sulfide in various biological matrices

(2009) Albert Tangerman   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Mitigation of peroxynitrite-mediated nitric oxide (NO) toxicity as a mechanism of induced adaptive NO resistance in the CNS

(2009) Amy Bishop et al.   JOURNAL OF NEUROCHEMISTRY

Calpain-mediated activation of NO synthase in human neuroblastoma SK-N-BE cells

(2009) Monica Averna et al.   JOURNAL OF NEUROCHEMISTRY

Heme oxygenase-1 and neurodegeneration: expanding frontiers of engagement

(2009) Hyman M. Schipper et al.   JOURNAL OF NEUROCHEMISTRY

The SIRT1 activator resveratrol protects SK-N-BE cells from oxidative stress and against toxicity caused by α-synuclein or amyloid-β (1-42) peptide

(2009) Diego Albani et al.   JOURNAL OF NEUROCHEMISTRY

Liver X receptor agonist treatment regulates inflammatory response after spinal cord trauma

(2009) Irene Paterniti et al.   JOURNAL OF NEUROCHEMISTRY

Histone Deacetylases 1 and 2 Form a Developmental Switch That Controls Excitatory Synapse Maturation and Function

(2009) M. W. Akhtar et al.   JOURNAL OF NEUROSCIENCE

Nrf2 activators provide neuroprotection against 6-hydroxydopamine toxicity in rat organotypic nigrostriatal cocultures

(2009) Aubrey Siebert et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Protein denitrosylation: enzymatic mechanisms and cellular functions

(2009) Moran Benhar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Astrocytes produce the antiinflammatory and neuroprotective agent hydrogen sulfide

(2009) Moonhee Lee et al.   NEUROBIOLOGY OF AGING

Hydrogen sulfide: A novel signaling molecule in the central nervous system

(2009) Boon Hian Tan et al.   NEUROCHEMISTRY INTERNATIONAL

NAD+ Availability and Proteotoxicity

(2009) Alan R. Hipkiss   NEUROMOLECULAR MEDICINE

Nicotinamide Prevents NAD+ Depletion and Protects Neurons Against Excitotoxicity and Cerebral Ischemia: NAD+ Consumption by SIRT1 may Endanger Energetically Compromised Neurons

(2009) Dong Liu et al.   NEUROMOLECULAR MEDICINE

Nitric Oxide as an Initiator of Brain Lesions During the Development of Alzheimer Disease

(2009) Gjumrakch Aliev et al.   NEUROTOXICITY RESEARCH

The function of NO-sensitive guanylyl cyclase: What we can learn from genetic mouse models

(2009) Andreas Friebe et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

A chemical chaperone, sodium 4-phenylbutyric acid, attenuates the pathogenic potency in human α-synuclein A30P+A53T transgenic mice

(2009) Kazuhiko Ono et al.   PARKINSONISM & RELATED DISORDERS

H2O2-mediated modulation of cytosolic signaling and organelle function in rat hippocampus

(2009) Florian J. Gerich et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte

(2009) Pei-Chun Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antioxidants prevent health-promoting effects of physical exercise in humans

(2009) M. Ristow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Hypoxia-Inducible Factor 2  Signaling by the Stress-Responsive Deacetylase Sirtuin 1

(2009) E. M. Dioum et al.   SCIENCE

Stress-Inducible Regulation of Heat Shock Factor 1 by the Deacetylase SIRT1

(2009) S. D. Westerheide et al.   SCIENCE

Anoxia-Induced NF-kB-Dependent Upregulation of NCX1 Contributes to Ca 2+ Refilling Into Endoplasmic Reticulum in Cortical Neurons

(2009) Rossana Sirabella et al.   STROKE

Increased Nrf2 Activation in Livers from Keap1-Knockdown Mice Increases Expression of Cytoprotective Genes that Detoxify Electrophiles more than those that Detoxify Reactive Oxygen Species

(2009) Scott A. Reisman et al.   TOXICOLOGICAL SCIENCES

NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer

(2009) John D. Hayes et al.   TRENDS IN BIOCHEMICAL SCIENCES

Protein S-nitrosylation in health and disease: a current perspective

(2009) Matthew W. Foster et al.   TRENDS IN MOLECULAR MEDICINE

Pleiotropic functions of biliverdin reductase: cellular signaling and generation of cytoprotective and cytotoxic bilirubin

(2009) Jaime Kapitulnik et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Mitochondrial nitric oxide synthase, mitochondrial brain dysfunction in aging, and mitochondria-targeted antioxidants☆

(2008) Ana Navarro et al.   ADVANCED DRUG DELIVERY REVIEWS

Ursodeoxycholic acid stimulates Nrf2-mediated hepatocellular transport, detoxification, and antioxidative stress systems in mice

(2008) Kosuke Okada et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Decline in NRF2-regulated Antioxidants in Chronic Obstructive Pulmonary Disease Lungs Due to Loss of Its Positive Regulator, DJ-1

(2008) Deepti Malhotra et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The Nrf2/ARE Pathway as a Potential Therapeutic Target in Neurodegenerative Disease

(2008) Marcus J. Calkins et al.   ANTIOXIDANTS & REDOX SIGNALING

A Source of Hydrogen Sulfide and a Mechanism of Its Release in the Brain

(2008) Mari Ishigami et al.   ANTIOXIDANTS & REDOX SIGNALING

PGC-1α-mediated regulation of gene expression and metabolism: implications for nutrition and exercise prescriptions

(2008) Carley R. Benton et al.   Applied Physiology Nutrition and Metabolism

Simple ortho- and para-hydroquinones as compounds neuroprotective against oxidative stress in a manner associated with specific transcriptional activation

(2008) Takumi Satoh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SIRT1 regulates the ribosomal DNA locus: Epigenetic candles twinkle longevity in the Christmas tree

(2008) Antero Salminen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Two Distinct Disulfide Bonds Formed in Human Heat Shock Transcription Factor 1 Act in Opposition To Regulate Its DNA Binding Activity†

(2008) Ming Lu et al.   BIOCHEMISTRY

Therapeutic role of sirtuins in neurodegenerative disease

(2008) Tiago Fleming Outeiro et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

SIRT1 longevity factor suppresses NF-κB -driven immune responses: regulation of aging via NF-κB acetylation?

(2008) Antero Salminen et al.   BIOESSAYS

Toll-like receptors in neurodegeneration

(2008) Eitan Okun et al.   BRAIN RESEARCH REVIEWS

Superoxide Flashes in Single Mitochondria

(2008) Wang Wang et al.   CELL

SirT1 Inhibition Reduces IGF-I/IRS-2/Ras/ERK1/2 Signaling and Protects Neurons

(2008) Ying Li et al.   Cell Metabolism

Preinduction of HSP70 promotes hypoxic tolerance and facilitates acclimatization to acute hypobaric hypoxia in mouse brain

(2008) Kuan Zhang et al.   CELL STRESS & CHAPERONES

Two-Step Mechanism of Induction of the Gene Expression of a Prototypic Cancer-Protective Enzyme by Diphenols

(2008) René V. Bensasson et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Astrocytes: Adaptive Responses to Low Doses of Neurotoxins

(2008) Edward J. Calabrese   CRITICAL REVIEWS IN TOXICOLOGY

Dose-Response Features of Neuroprotective Agents: An Integrative Summary

(2008) Edward J. Calabrese   CRITICAL REVIEWS IN TOXICOLOGY

Enhancing and Regulating Neurite Outgrowth

(2008) Edward J. Calabrese   CRITICAL REVIEWS IN TOXICOLOGY

Neuroscience and Hormesis: Overview and General Findings

(2008) Edward J. Calabrese   CRITICAL REVIEWS IN TOXICOLOGY

P-Glycoprotein Efflux Transporter Activity Often Displays Biphasic Dose-Response Relationships

(2008) Edward J. Calabrese   CRITICAL REVIEWS IN TOXICOLOGY

Stress Biology and Hormesis: The Yerkes–Dodson Law in Psychology—A Special Case of the Hormesis Dose Response

(2008) Edward J. Calabrese   CRITICAL REVIEWS IN TOXICOLOGY

Drug Therapies for Stroke and Traumatic Brain Injury Often Display U-Shaped Dose Responses: Occurrence, Mechanisms, and Clinical Implications

(2008) Edward J. Calabrese   CRITICAL REVIEWS IN TOXICOLOGY

An Assessment of Anxiolytic Drug Screening Tests: Hormetic Dose Responses Predominate

(2008) Edward J. Calabrese   CRITICAL REVIEWS IN TOXICOLOGY

Alzheimer's Disease Drugs: An Application of the Hormetic Dose-Response Model

(2008) Edward J. Calabrese   CRITICAL REVIEWS IN TOXICOLOGY

Modulation of the Epileptic Seizure Threshold: Implications of Biphasic Dose Responses

(2008) Edward J. Calabrese   CRITICAL REVIEWS IN TOXICOLOGY

Pharmacological Enhancement of Neuronal Survival

(2008) Edward J. Calabrese   CRITICAL REVIEWS IN TOXICOLOGY

Chaperone machines in action

(2008) Helen R Saibil   CURRENT OPINION IN STRUCTURAL BIOLOGY

Hormesis [Biological Effects of Low Level Exposures (Belle)] and Dermatology

(2008) Haw-Yueh Thong et al.   Dose-Response

Hormesis and plant biology

(2008) Edward J. Calabrese et al.   ENVIRONMENTAL POLLUTION

HORMESIS: WHY IT IS IMPORTANT TO TOXICOLOGY AND TOXICOLOGISTS

(2008) Edward J. Calabrese   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Effect of S-diclofenac, a novel hydrogen sulfide releasing derivative inhibit rat vascular smooth muscle cell proliferation

(2008) Rajamanickam Baskar et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The unexpected role of acid sphingomyelinase in cell death and the pathophysiology of common diseases

(2008) Eric L. Smith et al.   FASEB JOURNAL

Hydrogen sulfide protects astrocytes against H2O2-induced neural injury via enhancing glutamate uptake

(2008) Ming Lu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Carbon monoxide, reactive oxygen signaling, and oxidative stress

(2008) Claude A. Piantadosi   FREE RADICAL BIOLOGY AND MEDICINE

Age-associated oxidative damage to the p62 promoter: implications for Alzheimer disease

(2008) Yifeng Du et al.   FREE RADICAL BIOLOGY AND MEDICINE

Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging

(2008) R. I. Morimoto   GENES & DEVELOPMENT

Vasoactive intestinal peptide protects against β-amyloid-induced neurodegeneration by inhibiting microglia activation at multiple levels

(2008) Mario Delgado et al.   GLIA

Hormesis Predicts Low-Dose Responses Better Than Threshold Models

(2008) Edward J. Calabrese et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Structural Classification of Toxic Amyloid Oligomers

(2008) Charles G. Glabe   JOURNAL OF BIOLOGICAL CHEMISTRY

Life Span Extension and Neuronal Cell Protection byDrosophilaNicotinamidase

(2008) Vitaly Balan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Direct Redox Regulation of Protein Kinase C Isoenzymes Mediates Oxidant-induced Neuritogenesis in PC12 Cells

(2008) Rayudu Gopalakrishna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lifelong running reduces oxidative stress and degenerative changes in the testes of mice

(2008) Srinivasulu Chigurupati et al.   JOURNAL OF ENDOCRINOLOGY

Genetic inactivation of p62 leads to accumulation of hyperphosphorylated tau and neurodegeneration

(2008) J. Ramesh Babu et al.   JOURNAL OF NEUROCHEMISTRY

Superoxide-Induced Potentiation in the Hippocampus Requires Activation of Ryanodine Receptor Type 3 and ERK

(2008) A. Tara Huddleston et al.   JOURNAL OF NEUROPHYSIOLOGY

Nicotinamide Restores Cognition in Alzheimer's Disease Transgenic Mice via a Mechanism Involving Sirtuin Inhibition and Selective Reduction of Thr231-Phosphotau

(2008) K. N. Green et al.   JOURNAL OF NEUROSCIENCE

Nrf2 Activation in Astrocytes Protects against Neurodegeneration in Mouse Models of Familial Amyotrophic Lateral Sclerosis

(2008) M. R. Vargas et al.   JOURNAL OF NEUROSCIENCE

Structural insights into the similar modes of Nrf2 transcription factor recognition by the cytoplasmic repressor Keap1

(2008) Balasundaram Padmanabhan et al.   JOURNAL OF SYNCHROTRON RADIATION

Efficacy and safety of oral fumarate in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study

(2008) Ludwig Kappos et al.   LANCET

Beyond transcription factors: The role of chromatin modifying enzymes in regulating transcription required for memory

(2008) R. M. Barrett et al.   LEARNING & MEMORY

Activation of Heat Shock and Antioxidant Responses by the Natural Product Celastrol: Transcriptional Signatures of a Thiol-targeted Molecule

(2008) Amy Trott et al.   MOLECULAR BIOLOGY OF THE CELL

Curcumin and the cellular stress response in free radical-related diseases

(2008) Vittorio Calabrese et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Paraxanthine, the Primary Metabolite of Caffeine, Provides Protection against Dopaminergic Cell Death via Stimulation of Ryanodine Receptor Channels

(2008) S. Guerreiro et al.   MOLECULAR PHARMACOLOGY

Sirt1 contributes critically to the redox-dependent fate of neural progenitors

(2008) Timour Prozorovski et al.   NATURE CELL BIOLOGY

Sirtuins — novel therapeutic targets to treat age-associated diseases

(2008) Siva Lavu et al.   NATURE REVIEWS DRUG DISCOVERY

The insulin paradox: aging, proteotoxicity and neurodegeneration

(2008) Ehud Cohen et al.   NATURE REVIEWS NEUROSCIENCE

Cellular Stress Response: A Novel Target for Chemoprevention and Nutritional Neuroprotection in Aging, Neurodegenerative Disorders and Longevity

(2008) Vittorio Calabrese et al.   NEUROCHEMICAL RESEARCH

Neuroprotective potential of phase II enzyme inducer diallyl trisulfide

(2008) Meng-Meng Sun et al.   NEUROLOGICAL RESEARCH

Mitochondria in Neuroplasticity and Neurological Disorders

(2008) Mark P. Mattson et al.   NEURON

Endogenous neuroprotection: Mitochondria as gateways to cerebral preconditioning?

(2008) Ulrich Dirnagl et al.   NEUROPHARMACOLOGY

Brain inflammation and adult neurogenesis: The dual role of microglia

(2008) C.T. Ekdahl et al.   NEUROSCIENCE

Best in small doses

(2008) Mark Mattson et al.   NEW SCIENTIST

Chaperone-dependent stabilization and degradation of p53 mutants

(2008) P Muller et al.   ONCOGENE

Molecular chaperones as regulators of cell death

(2008) A Hishiya et al.   ONCOGENE

Opposing Effects of Sirtuins on Neuronal Survival: SIRT1-Mediated Neuroprotection Is Independent of Its Deacetylase Activity

(2008) Jason A. Pfister et al.   PLoS One

Role of the hsp70 cochaperone BAG1 in glucocorticoid receptor function and stress-related diseases

(2008) U. Schmidt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coordinate regulation of enzyme markers for inflammation and for protection against oxidants and electrophiles

(2008) H. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis

(2008) B.-H. Ahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adapting Proteostasis for Disease Intervention

(2008) William E. Balch et al.   SCIENCE

Genetic or Pharmacologic Amplification of Nrf2 Signaling Inhibits Acute Inflammatory Liver Injury in Mice

(2008) William O. Osburn et al.   TOXICOLOGICAL SCIENCES

Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease

(2008) Ilya Bezprozvanny et al.   TRENDS IN NEUROSCIENCES

Putative biological roles of hydrogen sulfide in health and disease: a breath of not so fresh air?

(2008) L LI et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Dietary factors, hormesis and health

(2007) Mark P. Mattson   AGEING RESEARCH REVIEWS

Astrocyte-Derived CO Is a Diffusible Messenger That Mediates Glutamate-Induced Cerebral Arteriolar Dilation by Activating Smooth Muscle Cell K Ca Channels

(2007) Anlong Li et al.   CIRCULATION RESEARCH

Production, detection, and adaptive responses to free radicals in exercise

(2007) Sean Sachdev et al.   FREE RADICAL BIOLOGY AND MEDICINE

Carnosic acid, acatechol-typeelectrophilic compound, protects neurons bothin vitroandin vivothrough activation of the Keap1/Nrf2 pathway viaS-alkylation of targeted cysteines on Keap1

(2007) Takumi Satoh et al.   JOURNAL OF NEUROCHEMISTRY

DNA methylation and histone acetylation work in concert to regulate memory formation and synaptic plasticity

(2007) Courtney A. Miller et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Hydrogen sulfide: Neurochemistry and neurobiology

(2007) K. Qu et al.   NEUROCHEMISTRY INTERNATIONAL

Neural Stem/Progenitor Cells Initiate the Formation of Cellular Networks That Provide Neuroprotection by Growth Factor-Modulated Antioxidant Expression

(2007) Lalitha Madhavan et al.   STEM CELLS