Therapies for Musculoskeletal Disease: Can we Treat Two Birds with One Stone?
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Title
Therapies for Musculoskeletal Disease: Can we Treat Two Birds with One Stone?
Authors
Keywords
Muscle, Bone, Anabolic agents, Osteoporosis, Sarcopenia
Journal
Current Osteoporosis Reports
Volume 12, Issue 2, Pages 142-153
Publisher
Springer Nature
Online
2014-03-18
DOI
10.1007/s11914-014-0204-5
References
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- (2013) Ralf Nass et al. ANNALS OF INTERNAL MEDICINE
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- (2013) R. Serrano-Urrea et al. GERONTOLOGY
- Forum on bone and skeletal muscle interactions: Summary of the proceedings of an ASBMR workshop
- (2013) Lynda F Bonewald et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Bone and Skeletal Muscle: Neighbors With Close Ties
- (2013) Douglas J DiGirolamo et al. JOURNAL OF BONE AND MINERAL RESEARCH
- A phase IIA randomized, placebo-controlled clinical trial to study the efficacy and safety of the selective androgen receptor modulator (SARM), MK-0773 in female participants with sarcopenia
- (2013) Dimitris A. Papanicolaou et al. Journal of Nutrition Health & Aging
- Increased Muscle Force Production and Bone Mineral Density in ActRIIB-Fc-Treated Mature Rodents
- (2013) C.-S. Chiu et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Effects of enobosarm on muscle wasting and physical function in patients with cancer: a double-blind, randomised controlled phase 2 trial
- (2013) Adrian S Dobs et al. LANCET ONCOLOGY
- An Antibody Blocking Activin Type II Receptors Induces Strong Skeletal Muscle Hypertrophy and Protects from Atrophy
- (2013) E. Lach-Trifilieff et al. MOLECULAR AND CELLULAR BIOLOGY
- Risks and benefits of testosterone therapy in older men
- (2013) Matthew Spitzer et al. Nature Reviews Endocrinology
- Operational definitions of sarcopenia and their associations with 5-year changes in falls risk in community-dwelling middle-aged and older adults
- (2013) D. Scott et al. OSTEOPOROSIS INTERNATIONAL
- Additive association of vitamin D insufficiency and sarcopenia with low femoral bone mineral density in noninstitutionalized elderly population: the Korea National Health and Nutrition Examination Surveys 2009–2010
- (2013) S.-G. Lee et al. OSTEOPOROSIS INTERNATIONAL
- The Effects of Exercise Training in Addition to Energy Restriction on Functional Capacities and Body Composition in Obese Adults during Weight Loss: A Systematic Review
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- Myostatin – The Holy Grail for Muscle, Bone, and Fat?
- (2013) B. Buehring et al. Current Osteoporosis Reports
- The central role of myostatin in skeletal muscle and whole body homeostasis
- (2012) B. Elliott et al. Acta Physiologica
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- (2012) Yongji Wang et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Muscle Strength and Body Composition Are Clinical Indicators of Osteoporosis
- (2012) Toni Rikkonen et al. CALCIFIED TISSUE INTERNATIONAL
- Activin signaling as an emerging target for therapeutic interventions
- (2012) Kunihiro Tsuchida et al. Cell Communication and Signaling
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- (2012) Matthew Bowser et al. EXPERIMENTAL GERONTOLOGY
- Deciphering the selective androgen receptor modulators paradigm
- (2012) Xuqing Zhang et al. Expert Opinion on Drug Discovery
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- (2012) Lowenna J. Holt et al. FASEB JOURNAL
- Skeletal muscle mass is associated with bone geometry and microstructure and serum insulin-like growth factor binding protein-2 levels in adult women and men
- (2012) Nathan K LeBrasseur et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Normocalcemia is maintained in mice under conditions of calcium malabsorption by vitamin D–induced inhibition of bone mineralization
- (2012) Liesbet Lieben et al. JOURNAL OF CLINICAL INVESTIGATION
- The Safety, Pharmacokinetics, and Effects of LGD-4033, a Novel Nonsteroidal Oral, Selective Androgen Receptor Modulator, in Healthy Young Men
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- A single ascending-dose study of muscle regulator ace-031 in healthy volunteers
- (2012) Kenneth M. Attie et al. MUSCLE & NERVE
- Muscles, exercise and obesity: skeletal muscle as a secretory organ
- (2012) Bente K. Pedersen et al. Nature Reviews Endocrinology
- The skeleton as an endocrine organ
- (2012) Douglas J. DiGirolamo et al. Nature Reviews Rheumatology
- Frailty and sarcopenia: definitions and outcome parameters
- (2012) C. Cooper et al. OSTEOPOROSIS INTERNATIONAL
- Strength training stops bone loss and builds muscle in postmenopausal breast cancer survivors: a randomized, controlled trial
- (2011) Kerri M. Winters-Stone et al. BREAST CANCER RESEARCH AND TREATMENT
- Serum myostatin levels and grip strength in normal subjects and patients on maintenance haemodialysis
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- (2011) A. Sharir et al. DEVELOPMENT
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- (2010) Sebastio Perrini et al. JOURNAL OF ENDOCRINOLOGY
- Developing bones are differentially affected by compromised skeletal muscle formation
- (2009) Niamh C. Nowlan et al. BONE
- Muscle Contraction Is Necessary to Maintain Joint Progenitor Cell Fate
- (2009) Joy Kahn et al. DEVELOPMENTAL CELL
- Effects of an Oral Growth Hormone Secretagogue in Older Adults
- (2009) Heidi K. White et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Nonsteroidal Selective Androgen Receptor Modulators (SARMs): Dissociating the Anabolic and Androgenic Activities of the Androgen Receptor for Therapeutic Benefit
- (2009) Michael L. Mohler et al. JOURNAL OF MEDICINAL CHEMISTRY
- Muscle and bone plasticity after spinal cord injury: Review of adaptations to disuse and to electrical muscle stimulation
- (2009) Shauna Dudley-Javoroski JOURNAL OF REHABILITATION RESEARCH AND DEVELOPMENT
- A phase I/IItrial of MYO-029 in adult subjects with muscular dystrophy
- (2008) Kathryn R. Wagner et al. ANNALS OF NEUROLOGY
- Meta-analysis of walking for preservation of bone mineral density in postmenopausal women
- (2008) Marrissa Martyn-St James et al. BONE
- Myostatin (GDF-8) deficiency increases fracture callus size, Sox-5 expression, and callus bone volume
- (2008) Ethan Kellum et al. BONE
- Reduction in proximal femoral strength due to long-duration spaceflight
- (2008) J.H. Keyak et al. BONE
- Anti-Aging Therapy With Human Growth Hormone Associated With Metastatic Colon Cancer in a Patient With Crohn’s Colitis
- (2008) Gil Y. Melmed et al. Clinical Gastroenterology and Hepatology
- Dietary protein recommendations and the prevention of sarcopenia
- (2008) Douglas Paddon-Jones et al. CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
- Growth Hormone, Insulin-Like Growth Factors, and the Skeleton
- (2008) Andrea Giustina et al. ENDOCRINE REVIEWS
- Role of the GH/IGF-1 axis in lifespan and healthspan: Lessons from animal models
- (2008) Darlene E. Berryman et al. GROWTH HORMONE & IGF RESEARCH
- Comparison of the healing of open tibial fractures covered with either muscle or fasciocutaneous tissue in a murine model
- (2008) Lorraine E. Harry et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Single muscle fiber contractile properties in adults with muscular dystrophy treated with MYO-029
- (2008) Lisa S. Krivickas et al. MUSCLE & NERVE
- Human Sarcopenia Reveals an Increase in SOCS-3 and Myostatin and a Reduced Efficiency of Akt Phosphorylation
- (2008) Bertrand Léger et al. REJUVENATION RESEARCH
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