Effect of Anti-IL17 Antibody Treatment Alone and in Combination With Rho-Kinase Inhibitor in a Murine Model of Asthma

A Distribution-Moment Approximation for Coupled Dynamics of the Airway Wall and Airway Smooth Muscle

(2018) Anand K. Rampadarath et al.   BIOPHYSICAL JOURNAL

How to Control Asthma with Personalized Management: Where Do We Stand Now?

(2018) Meng Wang et al.   CURRENT DRUG METABOLISM

Functional differences in airway dendritic cells determine susceptibility to IgE-sensitization

(2018) Jonatan Leffler et al.   IMMUNOLOGY AND CELL BIOLOGY

Effects of Anti-IL-17 on Inflammation, Remodeling, and Oxidative Stress in an Experimental Model of Asthma Exacerbated by LPS

(2018) Leandro do Nascimento Camargo et al.   Frontiers in Immunology

Insight Into Non-Pathogenic Th17 Cells in Autoimmune Diseases

(2018) Xinyu Wu et al.   Frontiers in Immunology

Decorin and biglycan are necessary for maintaining collagen fibril structure, fiber realignment, and mechanical properties of mature tendons

(2017) Kelsey A. Robinson et al.   MATRIX BIOLOGY

Targeted inhibition of G q signaling induces airway relaxation in mouse models of asthma

(2017) Michaela Matthey et al.   Science Translational Medicine

ROCK regulates the intermittent mode of interstitial T cell migration in inflamed lungs

(2017) Paulus Mrass et al.   Nature Communications

Influence of an Allergen-Specific Th17 Response on Remodeling of the Airways

(2016) Marcus Peters et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

ROCK activity affects IL-1-induced signaling possibly through MKK4 and p38 MAPK in Caco-2 cells

(2016) Sayantan Banerjee et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Molecular Mechanisms of Airway Hyperresponsiveness in a Murine Model of Steroid-Resistant Airway Inflammation

(2016) Michelle L. Manni et al.   JOURNAL OF IMMUNOLOGY

IL-17RA Signaling in Airway Inflammation and Bronchial Hyperreactivity in Allergic Asthma

(2015) Cynthia R. Willis et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Gαq controls rheumatoid arthritis via regulation of Th17 differentiation

(2015) Yuan Liu et al.   IMMUNOLOGY AND CELL BIOLOGY

Characterization of a high TNF-α phenotype in children with moderate-to-severe asthma

(2015) Sheena D. Brown et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Identification of novel immune phenotypes for allergic and nonallergic childhood asthma

(2015) Diana Raedler et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

T H 2 and T H 17 inflammatory pathways are reciprocally regulated in asthma

(2015) David F. Choy et al.   Science Translational Medicine

Y-27632 is associated with corticosteroid-potentiated control of pulmonary remodeling and inflammation in guinea pigs with chronic allergic inflammation

(2015) Patricia Angeli Pigati et al.   BMC Pulmonary Medicine

Pulmonary Inflammation Is Regulated by the Levels of the Vesicular Acetylcholine Transporter

(2015) Nathalia M. Pinheiro et al.   PLoS One

Gαq signalling: The new and the old

(2014) Guzmán Sánchez-Fernández et al.   CELLULAR SIGNALLING

Cytoskeleton changes of airway smooth muscle cells in juvenile rats with airway remodeling in asthma and the RhoA/ROCK signaling pathway mechanism

(2014) B. Wei et al.   GENETICS AND MOLECULAR RESEARCH

The cell biology of asthma

(2014) David J. Erle et al.   JOURNAL OF CELL BIOLOGY

IL-17-Producing Alveolar Macrophages Mediate Allergic Lung Inflammation Related to Asthma

(2014) C. Song et al.   JOURNAL OF IMMUNOLOGY

Effects of Rho-kinase inhibition in lung tissue with chronic inflammation

(2014) Renato Fraga Righetti et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Controlled and uncontrolled asthma display distinct alveolar tissue matrix compositions

(2014) Maria Weitoft et al.   RESPIRATORY RESEARCH

Combined Inhibition of Tumor Necrosis Factor α and Interleukin-17 As a Therapeutic Opportunity in Rheumatoid Arthritis: Development and Characterization of a Novel Bispecific Antibody

(2014) Jens A. A. Fischer et al.   Arthritis & Rheumatology

IL-1 Family Cytokines Drive Th2 and Th17 Cells to Innocuous Airborne Antigens

(2013) Takao Kobayashi et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Effects of Interleukin-1β on Vascular Reactivity After Lipopolysaccharide-induced Endotoxic Shock in Rabbits and Its Relationship With PKC and Rho Kinase

(2013) Jia-lin Liang et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Modulation of the oscillatory mechanics of lung tissue and the oxidative stress response induced by arginase inhibition in a chronic allergic inflammation model

(2013) Luciana RCRB Aristoteles et al.   BMC Pulmonary Medicine

Rho-kinase inhibition attenuates airway responsiveness, inflammation, matrix remodeling, and oxidative stress activation induced by chronic inflammation

(2012) Samantha Souza Possa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Biglycan

(2012) Madalina V. Nastase et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β

(2012) Christina E. Zielinski et al.   NATURE

IL-17A produced by αβ T cells drives airway hyper-responsiveness in mice and enhances mouse and human airway smooth muscle contraction

(2012) Makoto Kudo et al.   NATURE MEDICINE

Isoprostanes and asthma

(2011) Judith A. Voynow et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Reciprocal expression of IL-25 and IL-17A is important for allergic airways hyperreactivity

(2011) J. L. Barlow et al.   CLINICAL AND EXPERIMENTAL ALLERGY

The Potential Role of Interleukin-17 in Severe Asthma

(2011) Yui-Hsi Wang et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Effects of inducible nitric oxide synthase inhibition in bronchial vascular remodeling-induced by chronic allergic pulmonary inflammation

(2011) Carla Máximo Prado et al.   EXPERIMENTAL LUNG RESEARCH

IL-13 Regulates Th17 Secretion of IL-17A in an IL-10-Dependent Manner

(2011) D. C. Newcomb et al.   JOURNAL OF IMMUNOLOGY

Expression of the T Helper 17-Associated Cytokines IL-17A and IL-17F in Asthma and COPD

(2010) Camille Doe et al.   CHEST

Oxidative stress and airway inflammation after allergen challenge evaluated by exhaled breath condensate analysis

(2010) L. Brussino et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Asthma: Clinical expression and molecular mechanisms

(2010) Robert F. Lemanske et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

RhoA, a Possible Target for Treatment of Airway Hyperresponsiveness in Bronchial Asthma

(2010) Yoshihiko Chiba et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Decorin modulates collagen I-stimulated, but not fibronectin-stimulated, migration of C2C12 myoblasts

(2010) K.P. Goetsch et al.   MATRIX BIOLOGY

Complement-mediated regulation of the IL-17A axis is a central genetic determinant of the severity of experimental allergic asthma

(2010) Stephane Lajoie et al.   NATURE IMMUNOLOGY

An Official American Thoracic Society/European Respiratory Society Statement: Asthma Control and Exacerbations

(2009) Helen K. Reddel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Arginase: a key enzyme in the pathophysiology of allergic asthma opening novel therapeutic perspectives

(2009) Harm Maarsingh et al.   BRITISH JOURNAL OF PHARMACOLOGY

Role of Ca2+mobilization and Ca2+sensitization in 8-iso-PGF2α-induced contraction in airway smooth muscle

(2009) A. Shiraki et al.   CLINICAL AND EXPERIMENTAL ALLERGY

The inhaled Rho kinase inhibitor Y-27632 protects against allergen-induced acute bronchoconstriction, airway hyperresponsiveness, and inflammation

(2008) Dedmer Schaafsma et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

IL-23 and Th17 Cells Enhance Th2-Cell–mediated Eosinophilic Airway Inflammation in Mice

(2008) Hidefumi Wakashin et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Nuclear Factor-κB Activation in Airway Epithelium Induces Inflammation and Hyperresponsiveness

(2008) Cristen Pantano et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Rho-kinase and contractile apparatus proteins in murine airway hyperresponsiveness

(2008) Martin Witzenrath et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Arginase and pulmonary diseases

(2008) Harm Maarsingh et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Schistosoma japonicum infection modulates the development of allergen-induced airway inflammation in mice

(2008) Hong-mei Mo et al.   PARASITOLOGY RESEARCH

Effects of Residual Oil Fly Ash (ROFA) in Mice with Chronic Allergic Pulmonary Inflammation

(2008) Fernanda M. Arantes-Costa et al.   TOXICOLOGIC PATHOLOGY