Targeted inhibition of G q signaling induces airway relaxation in mouse models of asthma

A G Protein-biased Designer G Protein-coupled Receptor Useful for Studying the Physiological Relevance of Gq/11-dependent Signaling Pathways

(2016) Jianxin Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mapping physiological G protein-coupled receptor signaling pathways reveals a role for receptor phosphorylation in airway contraction

(2016) Sophie J. Bradley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The experimental power of FR900359 to study Gq-regulated biological processes

(2015) Ramona Schrage et al.   Nature Communications

Changing face of β2-adrenergic and muscarinic receptor therapies in asthma

(2014) Nastasia V Wasilewski et al.   CURRENT OPINION IN PHARMACOLOGY

RGD peptides induce relaxation of pulmonary arteries and airways via β3-integrins

(2014) Julia Welschoff et al.   FASEB JOURNAL

Conventional and Monocyte-Derived CD11b+ Dendritic Cells Initiate and Maintain T Helper 2 Cell-Mediated Immunity to House Dust Mite Allergen

(2013) Maud Plantinga et al.   IMMUNITY

Endocannabinoid anandamide mediates hypoxic pulmonary vasoconstriction

(2013) D. Wenzel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Decoding Signaling and Function of the Orphan G Protein-Coupled Receptor GPR17 with a Small-Molecule Agonist

(2013) S. Hennen et al.   Science Signaling

Identification of a Novel Vasoconstrictor Peptide Specific for the Systemic Circulation

(2012) Daniela Wenzel et al.   HYPERTENSION

Identification of Magnetic Nanoparticles for Combined Positioning and Lentiviral Transduction of Endothelial Cells

(2012) Daniela Wenzel et al.   PHARMACEUTICAL RESEARCH

The role of extracellular-signal regulate kinase (ERK) in the regulation of airway tone in porcine isolated peripheral bronchioles

(2011) Alice Lelliott et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Applying label-free dynamic mass redistribution technology to frame signaling of G protein–coupled receptors noninvasively in living cells

(2011) Ralf Schröder et al.   Nature Protocols

Deconvolution of complex G protein–coupled receptor signaling in live cells using dynamic mass redistribution measurements

(2010) Ralf Schröder et al.   NATURE BIOTECHNOLOGY

β 2 -Adrenoceptor Antagonist ICI 118,551 Decreases Pulmonary Vascular Tone in Mice via a G i/o Protein/Nitric Oxide-Coupled Pathway

(2009) Daniela Wenzel et al.   HYPERTENSION

The C-terminal Tail of CRTH2 Is a Key Molecular Determinant That Constrains Gαiand Downstream Signaling Cascade Activation

(2008) Ralf Schröder et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biological properties of a specific Gαq/11 inhibitor, YM-254890, on platelet functions and thrombus formation under high-shear stress

(2006) Toshio Uemura et al.   BRITISH JOURNAL OF PHARMACOLOGY