- Home
- Publications
- Publication Search
- Publication Details
Title
Diabetes, pancreatic cancer, and metformin therapy
Authors
Keywords
-
Journal
Frontiers in Physiology
Volume 5, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2014-11-07
DOI
10.3389/fphys.2014.00426
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Profiling and targeting of cellular bioenergetics: inhibition of pancreatic cancer cell proliferation
- (2014) G Cheng et al. BRITISH JOURNAL OF CANCER
- Repurposing of Metformin and Aspirin by Targeting AMPK-mTOR and Inflammation for Pancreatic Cancer Prevention and Treatment
- (2014) W. Yue et al. Cancer Prevention Research
- Abstract 5405: Limiting glucose availability with metformin increased reactive oxygen species, decreased cell survival, and promoted apoptosis in human and mouse pancreatic cancer cells.
- (2014) Guang Yan et al. CANCER RESEARCH
- Factors That Affect Risk for Pancreatic Disease in the General Population: A Systematic Review and Meta-analysis of Prospective Cohort Studies
- (2014) Ammar Alsamarrai et al. Clinical Gastroenterology and Hepatology
- Metformin is associated with reduced risk of pancreatic cancer in patients with type 2 diabetes mellitus: A systematic review and meta-analysis
- (2014) Zheng Wang et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- A modular and flexible ESC-based mouse model of pancreatic cancer
- (2014) M. Saborowski et al. GENES & DEVELOPMENT
- Targeting mTOR dependency in pancreatic cancer
- (2014) Douglas C Morran et al. GUT
- Mechanism of Metformin-dependent Inhibition of Mammalian Target of Rapamycin (mTOR) and Ras Activity in Pancreatic Cancer
- (2014) Vijayalekshmi Nair et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function
- (2014) Andrea Viale et al. NATURE
- In Vitro and In Vivo Biological Evaluation of O-Carboxymethyl Chitosan Encapsulated Metformin Nanoparticles for Pancreatic Cancer Therapy
- (2014) K. S. Snima et al. PHARMACEUTICAL RESEARCH
- Metformin Inhibits the IL-6-Induced Epithelial-Mesenchymal Transition and Lung Adenocarcinoma Growth and Metastasis
- (2014) Zhongquan Zhao et al. PLoS One
- Radiosensitization of Pancreatic Cancer Cells by Metformin through the AMPK Pathway
- (2014) Aisha Fasih et al. RADIATION RESEARCH
- Antidiabetic Drug Metformin Prevents Progression of Pancreatic Cancer by Targeting in Part Cancer Stem Cells and mTOR Signaling
- (2014) Altaf Mohammed et al. Translational Oncology
- Optimum chemotherapy in the management of metastatic pancreatic cancer
- (2014) Marwan Ghosn WORLD JOURNAL OF GASTROENTEROLOGY
- Mechanistic target of rapamycin (mTOR): a point of convergence in the action of insulin/IGF-1 and G protein-coupled receptor agonists in pancreatic cancer cells
- (2014) Enrique Rozengurt Frontiers in Physiology
- Metformin-mediated growth inhibition involves suppression of the IGF-I receptor signalling pathway in human pancreatic cancer cells
- (2013) Emelie Karnevi et al. BMC CANCER
- Metformin inhibits pancreatic cancer cell and tumor growth and downregulates Sp transcription factors
- (2013) V. Nair et al. CARCINOGENESIS
- Non-linear dose–response relationship between cigarette smoking and pancreatic cancer risk: Evidence from a meta-analysis of 42 observational studies
- (2013) Li Zou et al. EUROPEAN JOURNAL OF CANCER
- Hyperglycemia, Insulin Resistance, Impaired Pancreatic β-Cell Function, and Risk of Pancreatic Cancer
- (2013) Brian M. Wolpin et al. JNCI-Journal of the National Cancer Institute
- Contextual inhibition of fatty acid synthesis by metformin involves glucose-derived acetyl-CoA and cholesterol in pancreatic tumor cells
- (2013) Mary Jo Cantoria et al. Metabolomics
- Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway
- (2013) Jaekyoung Son et al. NATURE
- New insights into pancreatic cancer-induced paraneoplastic diabetes
- (2013) Raghuwansh P. Sah et al. Nature Reviews Gastroenterology & Hepatology
- Metformin Inhibits the Growth of Human Pancreatic Cancer Xenografts
- (2013) Krisztina Kisfalvi et al. PANCREAS
- Different Patterns of Akt and ERK Feedback Activation in Response to Rapamycin, Active-Site mTOR Inhibitors and Metformin in Pancreatic Cancer Cells
- (2013) Heloisa P. Soares et al. PLoS One
- Low Concentrations of Metformin Selectively Inhibit CD133+ Cell Proliferation in Pancreatic Cancer and Have Anticancer Action
- (2013) Shanmiao Gou et al. PLoS One
- Metformin Targets the Metabolic Achilles Heel of Human Pancreatic Cancer Stem Cells
- (2013) Enza Lonardo et al. PLoS One
- Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth
- (2013) H. A. Hirsch et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pancreatic adenocarcinoma: ESMO-ESDO Clinical Practice Guidelines for diagnosis, treatment and follow-up
- (2012) T. Seufferlein et al. ANNALS OF ONCOLOGY
- Metformin inhibition of mTORC1 activation, DNA synthesis and proliferation in pancreatic cancer cells: Dependence on glucose concentration and role of AMPK
- (2012) James Sinnett-Smith et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Diabetes and risk of pancreatic cancer: a pooled analysis from the pancreatic cancer cohort consortium
- (2012) Joanne W. Elena et al. CANCER CAUSES & CONTROL
- Metformin Reduces Endogenous Reactive Oxygen Species and Associated DNA Damage
- (2012) C. Algire et al. Cancer Prevention Research
- O-Carboxymethyl chitosan nanoparticles for metformin delivery to pancreatic cancer cells
- (2012) K.S. Snima et al. CARBOHYDRATE POLYMERS
- Metformin Use Is Associated with Better Survival of Diabetic Patients with Pancreatic Cancer
- (2012) N. Sadeghi et al. CLINICAL CANCER RESEARCH
- Metformin alters the expression profiles of microRNAs in human pancreatic cancer cells
- (2012) Weiguang Li et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Adrenomedullin is Up-regulated in Patients With Pancreatic Cancer and Causes Insulin Resistance in β Cells and Mice
- (2012) Gaurav Aggarwal et al. GASTROENTEROLOGY
- A Prospective Study of Plasma Adiponectin and Pancreatic Cancer Risk in Five US Cohorts
- (2012) Ying Bao et al. JNCI-Journal of the National Cancer Institute
- Mouse models link metabolism and deubiquitination with Kras
- (2012) Rebecca Kirk Nature Reviews Clinical Oncology
- Prevalence of Diabetes Mellitus in Pancreatic Cancer Compared to Common Cancers
- (2012) Gaurav Aggarwal et al. PANCREAS
- Management strategies in pancreatic cancer
- (2011) C. J. Campen et al. AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY
- Metformin Inhibits Cell Proliferation, Migration and Invasion by Attenuating CSC Function Mediated by Deregulating miRNAs in Pancreatic Cancer Cells
- (2011) B. Bao et al. Cancer Prevention Research
- Metformin, Independent of AMPK, Induces mTOR Inhibition and Cell-Cycle Arrest through REDD1
- (2011) I. Ben Sahra et al. CANCER RESEARCH
- Metformin Decreases the Dose of Chemotherapy for Prolonging Tumor Remission in Mouse Xenografts Involving Multiple Cancer Cell Types
- (2011) D. Iliopoulos et al. CANCER RESEARCH
- Diabetes mellitus and risk of pancreatic cancer: A meta-analysis of cohort studies
- (2011) Qiwen Ben et al. EUROPEAN JOURNAL OF CANCER
- Diabetes and pancreatic cancer
- (2011) Donghui Li MOLECULAR CARCINOGENESIS
- FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer
- (2011) Thierry Conroy et al. NEW ENGLAND JOURNAL OF MEDICINE
- PTEN Is a Major Tumor Suppressor in Pancreatic Ductal Adenocarcinoma and Regulates an NF-κB–Cytokine Network
- (2011) Haoqiang Ying et al. Cancer Discovery
- Mechanism of the mitogenic influence of hyperinsulinemia
- (2011) Boris Draznin Diabetology & Metabolic Syndrome
- Anthropometric Measures, Body Mass Index, and Pancreatic Cancer
- (2010) Alan A. Arslan ARCHIVES OF INTERNAL MEDICINE
- Pancreatic cancer in chronic pancreatitis; aetiology, incidence, and early detection
- (2010) Sara Raimondi et al. BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY
- The complexities of obesity and diabetes with the development and progression of pancreatic cancer
- (2010) Bin Bao et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Body mass index, effect modifiers, and risk of pancreatic cancer: a pooled study of seven prospective cohorts
- (2010) Li Jiao et al. CANCER CAUSES & CONTROL
- Metformin against TGFβ-induced epithelial-to-mesenchymal transition (EMT): From cancer stem cells to aging-associated fibrosis
- (2010) Sílvia Cufí et al. CELL CYCLE
- Metformin, Independent of AMPK, Inhibits mTORC1 in a Rag GTPase-Dependent Manner
- (2010) Adem Kalender et al. Cell Metabolism
- Crosstalk between Insulin/Insulin-like Growth Factor-1 Receptors and G Protein-Coupled Receptor Signaling Systems: A Novel Target for the Antidiabetic Drug Metformin in Pancreatic Cancer
- (2010) E. Rozengurt et al. CLINICAL CANCER RESEARCH
- Metformin: Taking away the candy for cancer?
- (2010) Mathilde Jalving et al. EUROPEAN JOURNAL OF CANCER
- A pooled analysis of 14 cohort studies of anthropometric factors and pancreatic cancer risk
- (2010) Jeanine M. Genkinger et al. INTERNATIONAL JOURNAL OF CANCER
- Metformin Disrupts Crosstalk between G Protein-Coupled Receptor and Insulin Receptor Signaling Systems and Inhibits Pancreatic Cancer Growth
- (2009) K. Kisfalvi et al. CANCER RESEARCH
- Insulin resistance and hyperinsulinaemia in the development and progression of cancer
- (2009) Ian F. Godsland CLINICAL SCIENCE
- The influence of glucose-lowering therapies on cancer risk in type 2 diabetes
- (2009) C. J. Currie et al. DIABETOLOGIA
- Alcohol drinking and pancreatic cancer risk: a meta-analysis of the dose-risk relation
- (2009) Irene Tramacere et al. INTERNATIONAL JOURNAL OF CANCER
- Prevalence and Clinical Profile of Pancreatic Cancer–Associated Diabetes Mellitus
- (2008) Rahul Pannala et al. GASTROENTEROLOGY
- IGF-1 Mediates PTEN Suppression and Enhances Cell Invasion and Proliferation via Activation of the IGF-1/PI3K/Akt Signaling Pathway in Pancreatic Cancer Cells
- (2008) Jiachi Ma et al. JOURNAL OF SURGICAL RESEARCH
- Tobacco and the risk of pancreatic cancer: a review and meta-analysis
- (2008) Simona Iodice et al. LANGENBECKS ARCHIVES OF SURGERY
- The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level
- (2008) I Ben Sahra et al. ONCOGENE
- Metformin induces apoptosis of pancreatic cancer cells
- (2008) Luo-Wei Wang et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Pancreatic Cancer–Associated Diabetes Mellitus: Prevalence and Temporal Association With Diagnosis of Cancer
- (2007) Suresh T. Chari et al. GASTROENTEROLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More