In Vitro and In Vivo Biological Evaluation of O-Carboxymethyl Chitosan Encapsulated Metformin Nanoparticles for Pancreatic Cancer Therapy

Metformin-stimulated AMPK-α1 promotes microvascular repair in acute lung injury

(2013) Ming-Yuan Jian et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Multifunctional calcium phosphate nano-contrast agent for combined nuclear, magnetic and near-infrared in vivo imaging

(2013) Anusha Ashokan et al.   BIOMATERIALS

Different Patterns of Akt and ERK Feedback Activation in Response to Rapamycin, Active-Site mTOR Inhibitors and Metformin in Pancreatic Cancer Cells

(2013) Heloisa P. Soares et al.   PLoS One

SHP-1 in Cell-Cycle Regulation

(2012) Pilar Lopez-Ruiz et al.   Anti-Cancer Agents in Medicinal Chemistry

In vitro and in vivoanti-tumor effect of metformin as a novel therapeutic agent in human oral squamous cell carcinoma

(2012) Qingqiong Luo et al.   BMC CANCER

O-Carboxymethyl chitosan nanoparticles for metformin delivery to pancreatic cancer cells

(2012) K.S. Snima et al.   CARBOHYDRATE POLYMERS

Metformin alters the expression profiles of microRNAs in human pancreatic cancer cells

(2012) Weiguang Li et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Metformin potentiates the effects of paclitaxel in endometrial cancer cells through inhibition of cell proliferation and modulation of the mTOR pathway

(2012) Rabbie K. Hanna et al.   GYNECOLOGIC ONCOLOGY

Metformin improves cardiac function in a nondiabetic rat model of post-MI heart failure

(2011) Meimei Yin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Cancer statistics, 2011

(2011) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Metformin Inhibits Cell Proliferation, Migration and Invasion by Attenuating CSC Function Mediated by Deregulating miRNAs in Pancreatic Cancer Cells

(2011) B. Bao et al.   Cancer Prevention Research

The antidiabetic drug metformin suppresses HER2 (erbB-2) oncoprotein overexpression via inhibition of the mTOR effector p70S6K1 in human breast carcinoma cells

(2011) Alejandro Vazquez-Martin et al.   CELL CYCLE

Metformin inhibits breast cancer cell growth, colony formation and induces cell cycle arrest in vitro

(2011) Irina N. Alimova et al.   CELL CYCLE

Metformin induces unique biological and molecular responses in triple negative breast cancer cells

(2011) Bolin Liu et al.   CELL CYCLE

Clinical Pharmacokinetics of Metformin

(2011) Garry G. Graham et al.   CLINICAL PHARMACOKINETICS

Novel Blood Biomarkers of Pancreatic Cancer–Associated Diabetes Mellitus Identified by Peripheral Blood–Based Gene Expression Profiles

(2010) Hai Huang et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Metformin inhibits P-glycoprotein expression via the NF-κB pathway and CRE transcriptional activity through AMPK activation

(2010) Hyung Gyun Kim et al.   BRITISH JOURNAL OF PHARMACOLOGY

Use of Cells Expressing γ Subunit Variants to Identify Diverse Mechanisms of AMPK Activation

(2010) Simon A. Hawley et al.   Cell Metabolism

Crosstalk between Insulin/Insulin-like Growth Factor-1 Receptors and G Protein-Coupled Receptor Signaling Systems: A Novel Target for the Antidiabetic Drug Metformin in Pancreatic Cancer

(2010) E. Rozengurt et al.   CLINICAL CANCER RESEARCH

Metformin: Taking away the candy for cancer?

(2010) Mathilde Jalving et al.   EUROPEAN JOURNAL OF CANCER

Metformin Disrupts Crosstalk between G Protein-Coupled Receptor and Insulin Receptor Signaling Systems and Inhibits Pancreatic Cancer Growth

(2009) K. Kisfalvi et al.   CANCER RESEARCH

Antidiabetic Therapies Affect Risk of Pancreatic Cancer

(2009) Donghui Li et al.   GASTROENTEROLOGY

In vitro metformin anti-neoplastic activity in epithelial ovarian cancer

(2008) Walter H. Gotlieb et al.   GYNECOLOGIC ONCOLOGY

The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level

(2008) I Ben Sahra et al.   ONCOGENE