Emodin Attenuates Lipopolysaccharide-Induced Acute Liver Injury via Inhibiting the TLR4 Signaling Pathway in vitro and in vivo

Effects of corilagin on alleviating cholestasis via farnesoid X receptor-associated pathways in vitro and in vivo

(2018) Fan Yang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Potential Medications or Compounds Acting on Toll-like Receptors in Cerebral Ischemia

(2018) Man Li et al.   Current Neuropharmacology

Intestinal alkaline phosphatase ameliorates experimental colitis via toll-like receptor 4-dependent pathway

(2018) Sung Wook Hwang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Emodin Alleviates Liver Fibrosis of Mice by Reducing Infiltration of Gr1hi Monocytes

(2018) Xiang-An Zhao et al.   Evidence-based Complementary and Alternative Medicine

Crocus sativus L. stigmas and byproducts: Qualitative fingerprint, antioxidant potentials and enzyme inhibitory activities

(2018) Luigi Menghini et al.   FOOD RESEARCH INTERNATIONAL

Inhibition of myocardial hypertrophy by magnesium isoglycyrrhizinate through the TLR4/NF-κB signaling pathway in mice

(2018) Donglai Ma et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Graminex Pollen: Phenolic Pattern, Colorimetric Analysis and Protective Effects in Immortalized Prostate Cells (PC3) and Rat Prostate Challenged with LPS

(2018) Marcello Locatelli et al.   MOLECULES

β-arrestin 2 attenuates lipopolysaccharide-induced liver injury via inhibition of TLR4/NF-κB signaling pathway-mediated inflammation in mice

(2018) Meng-Ping Jiang et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Esculentoside A ameliorates cecal ligation and puncture-induced acute kidney injury in rats

(2017) Guodong Sun et al.   EXPERIMENTAL ANIMALS

A presumed antagonistic LPS identifies distinct functional organization of TLR4 in mouse microglia

(2017) Christin Döring et al.   GLIA

Pentraxin-3 modulates lipopolysaccharide-induced inflammatory response and attenuates liver injury

(2017) Luis Perea et al.   HEPATOLOGY

Gold-quercetin nanoparticles prevent metabolic endotoxemia-induced kidney injury by regulating TLR4/NF-kB signaling and Nrf2 pathway in high fat diet fed mice

(2017) Min-Xuan Xu et al.   International Journal of Nanomedicine

Pro-inflammatory hepatic macrophages generate ROS through NADPH oxidase 2 via endocytosis of monomeric TLR4–MD2 complex

(2017) So Yeon Kim et al.   Nature Communications

Chlorogenic Acid Inhibits Liver Fibrosis by Blocking the miR-21-Regulated TGF-β1/Smad7 Signaling Pathway in Vitro and in Vivo

(2017) Fan Yang et al.   Frontiers in Pharmacology

A New Immunosuppressive Molecule Emodin Induces both CD4+FoxP3+ and CD8+CD122+ Regulatory T Cells and Suppresses Murine Allograft Rejection

(2017) Feifei Qiu et al.   Frontiers in Immunology

Difference in the Inhibitory Effect of Temozolomide on TJ905 Glioma Cells and Stem Cells

(2017) Feng Jin et al.   Frontiers in Neurology

Corylin protects LPS-induced sepsis and attenuates LPS-induced inflammatory response

(2017) Yung-Li Hung et al.   Scientific Reports

NADPH oxidase 4 modulates hepatic responses to lipopolysaccharide mediated by Toll-like receptor-4

(2017) Anand Singh et al.   Scientific Reports

Preliminary study on Emodin alleviating alpha-naphthylisothiocyanate-induced intrahepatic cholestasis by regulation of liver farnesoid X receptor pathway

(2016) Yan Ding et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Emodin Bidirectionally Modulates Macrophage Polarization and Epigenetically Regulates Macrophage Memory

(2016) Stephen Iwanowycz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endoplasmic Reticulum Stress-induced Hepatocellular Death Pathways Mediate Liver Injury and Fibrosis via Stimulator of Interferon Genes

(2016) Arvin Iracheta-Vellve et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Changes in expression and production of heme oxygenase-1 in rats with acute liver injury induced by lipopolysaccharide

(2016) Juan Tang et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Dexmedetomidine may upregulate the expression of caveolin-1 in lung tissues of rats with sepsis and improve the short-term outcome

(2016) Yun Zhang et al.   Molecular Medicine Reports

Salidroside Regulates Inflammatory Response in Raw 264.7 Macrophages via TLR4/TAK1 and Ameliorates Inflammation in Alcohol Binge Drinking-Induced Liver Injury

(2016) Peng Sun et al.   MOLECULES

A CHALLENGING CASE OF SEVERE INFANTILE CHOLESTASIS IN ALPHA-1 ANTITRYPSIN DEFICIENCY

(2016) Zahida Khan et al.   PEDIATRIC AND DEVELOPMENTAL PATHOLOGY

An Hydroalcoholic Chamomile Extract Modulates Inflammatory and Immune Response in HT29 Cells and Isolated Rat Colon

(2016) Luigi Menghini et al.   PHYTOTHERAPY RESEARCH

PER1 prevents excessive innate immune response during endotoxin-induced liver injury through regulation of macrophage recruitment in mice

(2016) T Wang et al.   Cell Death & Disease

Profiles of responses of immunological factors to different subtypes of Kawasaki disease

(2015) Yan Ding et al.   BMC MUSCULOSKELETAL DISORDERS

EGFR kinase activity is required for TLR4 signaling and the septic shock response

(2015) S. Chattopadhyay et al.   EMBO REPORTS

Chilean Strawberry Consumption Protects against LPS-Induced Liver Injury by Anti-Inflammatory and Antioxidant Capability in Sprague-Dawley Rats

(2015) Sebastian Molinett et al.   Evidence-based Complementary and Alternative Medicine

Lipopolysaccharide-induced inflammatory liver injury in mice

(2015) K Hamesch et al.   LABORATORY ANIMALS

Involvement of TLR2 and TLR9 in the anti-inflammatory effects of chlorogenic acid in HSV-1-infected microglia

(2015) Yuan-Jin Guo et al.   LIFE SCIENCES

Protective effect ofSalvia miltiorrhizaandCarthamus tinctoriusextract against lipopolysaccharide-induced liver injury

(2015) Li-Na Gao   WORLD JOURNAL OF GASTROENTEROLOGY

TLR4-HMGB1-, MyD88- and TRIF-dependent signaling in mouse intestinal ischemia/reperfusion injury

(2015) Jie Wang   WORLD JOURNAL OF GASTROENTEROLOGY

Emodin attenuates systemic and liver inflammation in hyperlipidemic mice administrated with lipopolysaccharides

(2014) Xuemei Jia et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Emodin Ameliorates LPS-Induced Acute Lung Injury, Involving the Inactivation of NF-κB in Mice

(2014) Min Xiao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Corilagin Protects Against HSV1 Encephalitis Through Inhibiting the TLR2 Signaling Pathways In Vivo and In Vitro

(2014) Yuan-Jin Guo et al.   MOLECULAR NEUROBIOLOGY

Emodin Ameliorates Ethanol-Induced Fatty Liver Injury in Mice

(2014) Ying Liu et al.   PHARMACOLOGY

Echinacoside ameliorates D-galactosamine plus lipopolysaccharide-induced acute liver injury in mice via inhibition of apoptosis and inflammation

(2014) Xiuhui Li et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Sulforaphane inhibits the engagement of LPS with TLR4/MD2 complex by preferential binding to Cys133 in MD2

(2013) Jung Eun Koo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mesenchymal stem cells alleviate bacteria-induced liver injury in mice by inducing regulatory dendritic cells

(2013) Yi Zhang et al.   HEPATOLOGY

Macrophage biology in development, homeostasis and disease

(2013) Thomas A. Wynn et al.   NATURE

Dexamethasone Down-Regulates the Expression of microRNA-155 in the Livers of Septic Mice

(2013) Zhong-hua Wang et al.   PLoS One

Reduced Hepatic Injury in Toll-Like Receptor 4–Deficient Mice Following D-Galactosamine/Lipopolysaccharide-Induced Fulminant Hepatic Failure

(2012) Ziv Ben Ari et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Effects of simvastatin administration on rodents with lipopolysaccharide-induced liver microvascular dysfunction

(2012) Vincenzo La Mura et al.   HEPATOLOGY

Characterization of TLR4-mediated auto-antibody production in a mouse model of histidyl-tRNA synthetase-induced myositis

(2012) Lisa Harlow et al.   Innate Immunity

Liver Dysfunction and Phosphatidylinositol-3-Kinase Signalling in Early Sepsis: Experimental Studies in Rodent Models of Peritonitis

(2012) Peter Recknagel et al.   PLOS MEDICINE

Protective Effects of Emodin and Chrysophanol Isolated from Marine FungusAspergillus sp.on Ethanol-Induced Toxicity in HepG2/CYP2E1 Cells

(2011) Zhong-Ji Qian et al.   Evidence-based Complementary and Alternative Medicine

Inhibition of heat shock protein (molecular weight 90 kDa) attenuates proinflammatory cytokines and prevents lipopolysaccharide-induced liver injury in mice

(2011) Aditya Ambade et al.   HEPATOLOGY

Hepatoprotection of emodin andPolygonum multiflorumagainst CCl4-induced liver injury

(2011) Bao-Hong Lee et al.   PHARMACEUTICAL BIOLOGY

Trauma Hemorrhagic Shock-Induced Lung Injury Involves a Gut-Lymph-Induced TLR4 Pathway in Mice

(2011) Diego C. Reino et al.   PLoS One

Toll-Like Receptor 4 Stimulation Initiates an Inflammatory Response That Decreases Cardiomyocyte Contractility

(2010) Orna Avlas et al.   ANTIOXIDANTS & REDOX SIGNALING

Emodin suppresses lipopolysaccharide-induced pro-inflammatory responses and NF-κB activation by disrupting lipid rafts in CD14-negative endothelial cells

(2010) Guoquan Meng et al.   BRITISH JOURNAL OF PHARMACOLOGY

Effects of terbutaline on circulatory failure and organ dysfunction induced by peritonitis in rats

(2010) Cheng-Ming Tsao et al.   INTENSIVE CARE MEDICINE

Hepatic sinusoidal cells in health and disease: update from the 14th International Symposium

(2009) Bård Smedsrød et al.   LIVER INTERNATIONAL

Mechanisms of Toll-Like Receptor 4 (TLR4)-Mediated Inflammation After Cold Ischemia/Reperfusion in the Heart

(2009) David J. Kaczorowski et al.   TRANSPLANTATION

Emodin protects rat liver from CCl4-induced fibrogenesis via inhibition of hepatic stellate cells activation

(2009) Miao-Xian Dong et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Exploration of Emodin to treat alpha-naphthylisothiocyanate-induced cholestatic hepatitis via anti-inflammatory pathway

(2008) Yan Ding et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Taxanes inhibit human TLR4 signaling by binding to MD-2

(2008) Nuša Resman et al.   FEBS LETTERS