Chlorogenic Acid Inhibits Liver Fibrosis by Blocking the miR-21-Regulated TGF-β1/Smad7 Signaling Pathway in Vitro and in Vivo

Preliminary Exploration on Anti-Fibrosis Effect of Kaempferol in Mice with Schistosoma Japonicum Infection

(2017) Y-P. Zhou et al.   European Journal of Inflammation

Anti-Schistosomiasis liver fibrosis effects of chlorogenic acid through IL-13/miR-21/Smad7 signaling interactions in vivo and in vitro

(2016) Yao Wang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Chlorogenic acid protects against liver fibrosis in vivo and in vitro through inhibition of oxidative stress

(2016) Haitao Shi et al.   CLINICAL NUTRITION

Mechanism of Corilagin interference with IL-13/STAT6 signaling pathways in hepatic alternative activation macrophages in schistosomiasis-induced liver fibrosis in mouse model

(2016) Peng Du et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

NLRC5 regulates TGF-β1-induced proliferation and activation of hepatic stellate cells during hepatic fibrosis

(2016) Tao Xu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Preliminary study on Emodin alleviating alpha-naphthylisothiocyanate-induced intrahepatic cholestasis by regulation of liver farnesoid X receptor pathway

(2016) Yan Ding et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Phenylethanol Glycosides from Cistanche tubulosa Suppress Hepatic Stellate Cell Activation and Block the Conduction of Signaling Pathways in TGF-β1/smad as Potential Anti-Hepatic Fibrosis Agents

(2016) Shu-Ping You et al.   MOLECULES

Anti-hepatic fibrosis effects of a novel turtle shell decoction by inhibiting hepatic stellate cell proliferation and blocking TGF-β1/Smad signaling pathway in rats

(2016) Ganping Bai et al.   ONCOLOGY REPORTS

Corilagin ameliorates schistosomiasis hepatic fibrosis through regulating IL-13 associated signal pathway in vitro and in vivo

(2016) HUA-RONG LI et al.   PARASITOLOGY

Effect of Corilagin on the miR-21/smad7/ERK signaling pathway in a schistosomiasis-induced hepatic fibrosis mouse model

(2016) Fan Yang et al.   PARASITOLOGY INTERNATIONAL

Dioscin alleviates BDL- and DMN-induced hepatic fibrosis via Sirt1/Nrf2-mediated inhibition of p38 MAPK pathway

(2016) Lina Gu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Profiles of responses of immunological factors to different subtypes of Kawasaki disease

(2015) Yan Ding et al.   BMC MUSCULOSKELETAL DISORDERS

Pathological features of transplanted tumor established by CD133 positive TJ905 glioblastoma stem-like cells

(2015) Feng Jin et al.   Cancer Cell International

Quantitative chemical proteomics for investigating the biomarkers of dioscin against liver fibrosis caused by CCl4 in rats

(2015) Xiaoling Zhang et al.   CHEMICAL COMMUNICATIONS

Anti-inflammatory effect of chlorogenic acid on the IL-8 production in Caco-2 cells and the dextran sulphate sodium-induced colitis symptoms in C57BL/6 mice

(2015) Hee Soon Shin et al.   FOOD CHEMISTRY

Involvement of TLR2 and TLR9 in the anti-inflammatory effects of chlorogenic acid in HSV-1-infected microglia

(2015) Yuan-Jin Guo et al.   LIFE SCIENCES

Potent effects of dioscin against liver fibrosis

(2015) Xiaoling Zhang et al.   Scientific Reports

The effect of chlorogenic acid on blood pressure: a systematic review and meta-analysis of randomized clinical trials

(2014) I J Onakpoya et al.   JOURNAL OF HUMAN HYPERTENSION

Corilagin Protects Against HSV1 Encephalitis Through Inhibiting the TLR2 Signaling Pathways In Vivo and In Vitro

(2014) Yuan-Jin Guo et al.   MOLECULAR NEUROBIOLOGY

MicroRNA-21 activates hepatic stellate cells via PTEN/Akt signaling

(2013) Jun Wei et al.   BIOMEDICINE & PHARMACOTHERAPY

Anti-inflammatory and anti-oxidative effects of corilagin in a rat model of acute cholestasis

(2013) Feng Jin et al.   BMC GASTROENTEROLOGY

Antimicrobial effect and mode of action of chlorogenic acid on Staphylococcus aureus

(2013) Guanghui Li et al.   EUROPEAN FOOD RESEARCH AND TECHNOLOGY

Evolving therapies for liver fibrosis

(2013) Detlef Schuppan et al.   JOURNAL OF CLINICAL INVESTIGATION

Chlorogenic acid–phospholipid complex improve protection against UVA induced oxidative stress

(2013) Sauvik Bhattacharyya et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Regulation of hepatic stellate cells by connective tissue growth factor

(2012) Guangcun Huang   Frontiers in Bioscience-Landmark

Transforming growth factor-β1 induces epithelial–mesenchymal transition and integrin α3β1-mediated cell migration of HSC-4 human squamous cell carcinoma cells through Slug

(2012) Daishi Saito et al.   JOURNAL OF BIOCHEMISTRY

Pathogenesis of Liver Fibrosis

(2011) Virginia Hernandez-Gea et al.   Annual Review of Pathology-Mechanisms of Disease

TGF-β signal transduction spreading to a wider field: a broad variety of mechanisms for context-dependent effects of TGF-β

(2011) Hiroaki Ikushima et al.   CELL AND TISSUE RESEARCH

Increases in p53 expression induce CTGF synthesis by mouse and human hepatocytes and result in liver fibrosis in mice

(2011) Takahiro Kodama et al.   JOURNAL OF CLINICAL INVESTIGATION

IL-13 Induces Connective Tissue Growth Factor in Rat Hepatic Stellate Cells via TGF- -Independent Smad Signaling

(2011) Y. Liu et al.   JOURNAL OF IMMUNOLOGY

NF-κB in the liver—linking injury, fibrosis and hepatocellular carcinoma

(2011) Tom Luedde et al.   Nature Reviews Gastroenterology & Hepatology

Mechanism of the transforming growth factor-β induction of fibronectin expression in hepatic stem-like cells

(2010) W. Cui et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Protective effects of chlorogenic acid on acute hepatotoxicity induced by lipopolysaccharide in mice

(2010) Yuexin Xu et al.   INFLAMMATION RESEARCH

Correlation between microRNA expression levels and clinical parameters associated with chronic hepatitis C viral infection in humans

(2010) Rebecca T Marquez et al.   LABORATORY INVESTIGATION

Docking study on chlorogenic acid as a potential H5N1 influenza A virus neuraminidase inhibitor

(2010) Hua-Jun Luo et al.   MEDICINAL CHEMISTRY RESEARCH