Downregulation of MCT4 for lactate exchange promotes the cytotoxicity of NK cells in breast carcinoma

Evaluation of MCT1, MCT4 and CD147 Genes in Peripheral Blood Cells of Breast Cancer Patients and Their Potential Use as Diagnostic and Prognostic Markers

(2017) Maria Luz et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Composite analysis of immunological and metabolic markers defines novel subtypes of triple negative breast cancer

(2017) Thomas A Adams et al.   MODERN PATHOLOGY

Nuclear factor E2-related factor-2 has a differential impact on MCT1 and MCT4 lactate carrier expression in colonic epithelial cells: a condition favoring metabolic symbiosis between colorectal cancer and stromal cells

(2017) K Diehl et al.   ONCOGENE

Tumor Metabolism in the Microenvironment of Nodal Metastasis in Oral Squamous Cell Carcinoma

(2017) Joseph Curry et al.   OTOLARYNGOLOGY-HEAD AND NECK SURGERY

Mitochondrial and glycolytic metabolic compartmentalization in diffuse large B-cell lymphoma

(2017) Mahasweta Gooptu et al.   SEMINARS IN ONCOLOGY

Chronic NKG2D Engagement In Vivo Differentially Impacts NK Cell Responsiveness by Activating NK Receptors

(2017) Christine Koch et al.   Frontiers in Immunology

What Fuels Natural Killers? Metabolism and NK Cell Responses

(2017) Clair M. Gardiner et al.   Frontiers in Immunology

Disruption of the monocarboxylate transporter-4-basigin interaction inhibits the hypoxic response, proliferation, and tumor progression

(2017) Dillon M. Voss et al.   Scientific Reports

MCT1 and MCT4 Expression and Lactate Flux Activity Increase During White and Brown Adipogenesis and Impact Adipocyte Metabolism

(2017) Charlotte Petersen et al.   Scientific Reports

In Vivo Imaging of Tumor Metabolism and Acidosis by Combining PET and MRI-CEST pH Imaging

(2016) Dario L. Longo et al.   CANCER RESEARCH

Immunologic and Metabolic Features of Pancreatic Ductal Adenocarcinoma Define Prognostic Subtypes of Disease

(2016) J. Hutcheson et al.   CLINICAL CANCER RESEARCH

Tumor metabolism, cancer cell transporters, and microenvironmental resistance

(2016) Khalid O. Alfarouk   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Critical role of the NKG2D receptor for NK cell-mediated control and immune escape of B-cell lymphoma

(2015) Lena Belting et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Hypoxia, cancer metabolism and the therapeutic benefit of targeting lactate/H+ symporters

(2015) Ibtissam Marchiq et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Effective impairment of myeloma cells and their progenitors by blockade of monocarboxylate transportation

(2015) Derek James Hanson et al.   Oncotarget

Is the Tumor Infiltrating Natural Killer Cell (NK-TILs) Count in Infiltrating Ductal Carcinoma of Breast Prognostically Significant?

(2014) Ankita Singh Rathore et al.   Asian Pacific Journal of Cancer Prevention

High Monocarboxylate Transporter 4 Protein Expression in Stromal Cells Predicts Adverse Survival in Gastric Cancer

(2014) Ping Yan et al.   Asian Pacific Journal of Cancer Prevention

The Monocarboxylate Transporter 4 Is Required for Glycolytic Reprogramming and Inflammatory Response in Macrophages

(2014) Zheng Tan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Monocarboxylate transporter 4 predicts poor prognosis in hepatocellular carcinoma and is associated with cell proliferation and migration

(2014) Heng-Jun Gao et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Antitumor Activity of 7-Aminocarboxycoumarin Derivatives, a New Class of Potent Inhibitors of Lactate Influx but Not Efflux

(2014) N. Draoui et al.   MOLECULAR CANCER THERAPEUTICS

MCT4 Defines a Glycolytic Subtype of Pancreatic Cancer with Poor Prognosis and Unique Metabolic Dependencies

(2014) GuemHee Baek et al.   Cell Reports

Tumor-Derived Lactate Modifies Antitumor Immune Response: Effect on Myeloid-Derived Suppressor Cells and NK Cells

(2013) Z. Husain et al.   JOURNAL OF IMMUNOLOGY

Pyruvate fuels mitochondrial respiration and proliferation of breast cancer cells: effect of monocarboxylate transporter inhibition

(2012) Anne R. Diers et al.   BIOCHEMICAL JOURNAL

Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate

(2012) Patrick S. Ward et al.   CANCER CELL

Using the “reverse Warburg effect” to identify high-risk breast cancer patients

(2012) Agnieszka K. Witkiewicz et al.   CELL CYCLE

CD147 subunit of lactate/H+ symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumors

(2011) R. Le Floch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tumor pH and Its Measurement

(2010) X. Zhang et al.   JOURNAL OF NUCLEAR MEDICINE

Bicarbonate Increases Tumor pH and Inhibits Spontaneous Metastases

(2009) I. F. Robey et al.   CANCER RESEARCH

Evaluation of endogenous acidic metabolic products associated with carbohydrate metabolism in tumor cells

(2009) Elizabeth A. Mazzio et al.   CELL BIOLOGY AND TOXICOLOGY

Requirements for control of B-cell lymphoma by NK cells

(2009) Christoph D. Brenner et al.   EUROPEAN JOURNAL OF IMMUNOLOGY