CD147 subunit of lactate/H+ symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumors
Published 2011 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
CD147 subunit of lactate/H+ symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumors
Authors
Keywords
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 108, Issue 40, Pages 16663-16668
Publisher
Proceedings of the National Academy of Sciences
Online
2011-09-20
DOI
10.1073/pnas.1106123108
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Targeting Tumor Hypoxia: Suppression of Breast Tumor Growth and Metastasis by Novel Carbonic Anhydrase IX Inhibitors
- (2011) Y. Lou et al. CANCER RESEARCH
- Two ubiquitin ligases, APC/C-Cdh1 and SKP1-CUL1-F (SCF)- -TrCP, sequentially regulate glycolysis during the cell cycle
- (2011) S. Tudzarova et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hypoxia and energetic tumour metabolism
- (2010) M Christiane Brahimi-Horn et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Clues from cell metabolism
- (2010) William G. Kaelin et al. NATURE
- Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression
- (2010) A. Le et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- AR-C155858 is a potent inhibitor of monocarboxylate transporters MCT1 and MCT2 that binds to an intracellular site involving transmembrane helices 7–10
- (2009) Matthew J. Ovens et al. BIOCHEMICAL JOURNAL
- Epithelial-Mesenchymal Transitions in Development and Disease
- (2009) Jean Paul Thiery et al. CELL
- HIF-1: upstream and downstream of cancer metabolism
- (2009) Gregg L Semenza CURRENT OPINION IN GENETICS & DEVELOPMENT
- Tumor metabolism of lactate: the influence and therapeutic potential for MCT and CD147 regulation
- (2009) Kelly M Kennedy et al. Future Oncology
- CD147 silencing inhibits lactate transport and reduces malignant potential of pancreatic cancer cells in in vivo and in vitro models
- (2009) W Schneiderhan et al. GUT
- A Novel Role for Embigin to Promote Sprouting of Motor Nerve Terminals at the Neuromuscular Junction
- (2009) Enzo Lain et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Studies on the DIDS-binding Site of Monocarboxylate Transporter 1 Suggest a Homology Model of the Open Conformation and a Plausible Translocation Cycle
- (2009) Marieangela C. Wilson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Interaction of monocarboxylate transporter 4 with β1-integrin and its role in cell migration
- (2008) Shannon M. Gallagher et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Tumor Cell Metabolism: Cancer's Achilles' Heel
- (2008) Guido Kroemer et al. CANCER CELL
- Hypoxia-Inducible Carbonic Anhydrase IX and XII Promote Tumor Cell Growth by Counteracting Acidosis through the Regulation of the Intracellular pH
- (2008) J. Chiche et al. CANCER RESEARCH
- Isotype-specific inhibitors of the glycolytic key regulator pyruvate kinase subtype M2 moderately decelerate tumor cell proliferation
- (2008) Gilles A. Spoden et al. INTERNATIONAL JOURNAL OF CANCER
- Tumor-associated Carbonic Anhydrase 9 Spatially Coordinates Intracellular pH in Three-dimensional Multicellular Growths
- (2008) Pawel Swietach et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
- (2008) Heather R. Christofk et al. NATURE
- Targeted gene knockout in mammalian cells by using engineered zinc-finger nucleases
- (2008) Y. Santiago et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started