Metabolic Reprogramming of Clostridioides difficile During the Stationary Phase With the Induction of Toxin Production

Cwp19 Is a Novel Lytic Transglycosylase Involved in Stationary-Phase Autolysis Resulting in Toxin Release in Clostridium difficile

(2018) Sandra Wydau-Dematteis et al.   mBio

Flavin-Based Electron Bifurcation, Ferredoxin, Flavodoxin, and Anaerobic Respiration With Protons (Ech) or NAD+ (Rnf) as Electron Acceptors: A Historical Review

(2018) Wolfgang Buckel et al.   Frontiers in Microbiology

Shifts in the Gut Metabolome and Clostridium difficile Transcriptome throughout Colonization and Infection in a Mouse Model

(2018) Joshua R. Fletcher et al.   mSphere

A Novel Dual-cre Motif Enables Two-Way Autoregulation of CcpA in Clostridium acetobutylicum

(2018) Lu Zhang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Manual curation and reannotation of the genomes of Clostridium difficile 630Δerm and C. difficile 630

(2017) Henning Dannheim et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Spectral Library Based Analysis of Arginine Phosphorylations inStaphylococcus aureus

(2017) Sabryna Junker et al.   MOLECULAR & CELLULAR PROTEOMICS

Few regulatory metabolites coordinate expression of central metabolic genes in Escherichia coli

(2017) Karl Kochanowski et al.   Molecular Systems Biology

Codon optimality, bias and usage in translation and mRNA decay

(2017) Gavin Hanson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A Flexible Binding Site Architecture Provides New Insights into CcpA Global Regulation in Gram-Positive Bacteria

(2017) Yunpeng Yang et al.   mBio

Clostridioides difficile 630Δerm in silico and in vivo - quantitative growth and extensive polysaccharide secretion

(2017) Henning Dannheim et al.   FEBS Open Bio

Clostridium difficile Colonizes Alternative Nutrient Niches during Infection across Distinct Murine Gut Microbiomes

(2017) Matthew L. Jenior et al.   mSystems

Genome, transcriptome and proteome: the rise of omics data and their integration in biomedical sciences

(2016) Claudia Manzoni et al.   BRIEFINGS IN BIOINFORMATICS

Native plasmids restrict growth of Phaeobacter inhibens DSM 17395: Energetic costs of plasmids assessed by quantitative physiological analyses

(2016) Kathleen Trautwein et al.   ENVIRONMENTAL MICROBIOLOGY

Control of Clostridium difficile Physiopathology in Response to Cysteine Availability

(2016) Thomas Dubois et al.   INFECTION AND IMMUNITY

A systems biology approach reveals major metabolic changes in the thermoacidophilic archaeonSulfolobus solfataricusin response to the carbon source L-fucose versus D-glucose

(2016) Jacqueline Wolf et al.   MOLECULAR MICROBIOLOGY

The protein inventory ofClostridium difficilegrown in complex and minimal medium

(2016) Andreas Otto et al.   Proteomics Clinical Applications

Structural insight in the toppling mechanism of an energy-coupling factor transporter

(2016) Lotteke J. Y. M. Swier et al.   Nature Communications

Time-resolved amino acid uptake of Clostridium difficile 630Δerm and concomitant fermentation product and toxin formation

(2015) Meina Neumann-Schaal et al.   BMC MICROBIOLOGY

Interaction of theClostridium difficileBinary Toxin CDT and Its Host Cell Receptor, Lipolysis-stimulated Lipoprotein Receptor (LSR)

(2015) Sarah Hemmasi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Burden of Clostridium difficile Infection in the United States

(2015) Fernanda C. Lessa et al.   NEW ENGLAND JOURNAL OF MEDICINE

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

2016 update of the PRIDE database and its related tools

(2015) Juan Antonio Vizcaíno et al.   NUCLEIC ACIDS RESEARCH

Integration of metabolism and virulence in Clostridium difficile

(2015) Laurent Bouillaut et al.   RESEARCH IN MICROBIOLOGY

Picking Vanished Proteins from the Void: How to Collect and Ship/Share Extremely Dilute Proteins in a Reproducible and Highly Efficient Manner

(2014) Florian Bonn et al.   ANALYTICAL CHEMISTRY

A novel mode of lactate metabolism in strictly anaerobic bacteria

(2014) Marie Charlotte Weghoff et al.   ENVIRONMENTAL MICROBIOLOGY

T-cell activation by transitory neo-antigens derived from distinct microbial pathways

(2014) Alexandra J. Corbett et al.   NATURE

High-Throughput Screening of a Corynebacterium glutamicum Mutant Library on Genomic and Metabolic Level

(2014) Lorenz C. Reimer et al.   PLoS One

Bridging the gap between transcriptome and proteome measurements identifies post-translationally regulated genes

(2013) Y. Gunawardana et al.   BIOINFORMATICS

Adaptive Strategies and Pathogenesis of Clostridium difficile fromIn VivoTranscriptomics

(2013) Claire Janoir et al.   INFECTION AND IMMUNITY

Effect of an Oxygen-Tolerant Bifurcating Butyryl Coenzyme A Dehydrogenase/Electron-Transferring Flavoprotein Complex from Clostridium difficile on Butyrate Production in Escherichia coli

(2013) E.-H. Aboulnaga et al.   JOURNAL OF BACTERIOLOGY

Structure and mechanism of energy-coupling factor transporters

(2013) Peng Zhang   TRENDS IN MICROBIOLOGY

Antimicrobial-Resistant Strains of Clostridium difficile from North America

(2012) Fred C. Tenover et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Energy conservation via electron bifurcating ferredoxin reduction and proton/Na+ translocating ferredoxin oxidation

(2012) Wolfgang Buckel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Proline-Dependent Regulation of Clostridium difficile Stickland Metabolism

(2012) L. Bouillaut et al.   JOURNAL OF BACTERIOLOGY

Global transcriptional control by glucose and carbon regulator CcpA in Clostridium difficile

(2012) Ana Antunes et al.   NUCLEIC ACIDS RESEARCH

The Rnf Complex of Clostridium ljungdahlii Is a Proton-Translocating Ferredoxin:NAD+ Oxidoreductase Essential for Autotrophic Growth

(2012) P.-L. Tremblay et al.   mBio

Secretion of Clostridium difficile Toxins A and B Requires the Holin-like Protein TcdE

(2012) Revathi Govind et al.   PLoS Pathogens

Multidrug resistance in European Clostridium difficile clinical isolates

(2011) P. Spigaglia et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Transcriptional Regulation of Central Carbon and Energy Metabolism in Bacteria by Redox-Responsive Repressor Rex

(2011) D. A. Ravcheev et al.   JOURNAL OF BACTERIOLOGY

The Key Sigma Factor of Transition Phase, SigH, Controls Sporulation, Metabolism, and Virulence Factor Expression in Clostridium difficile

(2011) L. Saujet et al.   JOURNAL OF BACTERIOLOGY

Quantitative Proteomic Analysis of the Heat Stress Response inClostridium difficileStrain 630

(2011) Shailesh Jain et al.   JOURNAL OF PROTEOME RESEARCH

Time-Resolved Transcriptomics and Bioinformatic Analyses Reveal Intrinsic Stress Responses during Batch Culture of Bacillus subtilis

(2011) Evert-Jan Blom et al.   PLoS One

The Anti-Sigma Factor TcdC Modulates Hypervirulence in an Epidemic BI/NAP1/027 Clinical Isolate of Clostridium difficile

(2011) Glen P. Carter et al.   PLoS Pathogens

Clostridium sticklandii, a specialist in amino acid degradation:revisiting its metabolism through its genome sequence

(2010) Nuria Fonknechten et al.   BMC GENOMICS

Biochemistry, evolution and physiological function of the Rnf complex, a novel ion-motive electron transport complex in prokaryotes

(2010) Eva Biegel et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Integration of Metabolism and Virulence by Clostridium difficile CodY

(2010) S. S. Dineen et al.   JOURNAL OF BACTERIOLOGY

Metabolomic and transcriptomic stress response of Escherichia coli

(2010) Szymon Jozefczuk et al.   Molecular Systems Biology

Systems-wide temporal proteomic profiling in glucose-starved Bacillus subtilis

(2010) Andreas Otto et al.   Nature Communications

MetaboliteDetector: Comprehensive Analysis Tool for Targeted and Nontargeted GC/MS Based Metabolome Analysis

(2009) Karsten Hiller et al.   ANALYTICAL CHEMISTRY

A Proteomic View of an Important Human Pathogen – Towards the Quantification of the Entire Staphylococcus aureus Proteome

(2009) Dörte Becher et al.   PLoS One

Growth phase-dependent global protein and metabolite profiles ofPhaeobacter gallaeciensisstrain DSM 17395, a member of the marineRoseobacter-clade

(2009) Hajo Zech et al.   PROTEOMICS

Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium

(2009) Richard A Stabler et al.   GENOME BIOLOGY

Emergence of reduced susceptibility to metronidazole in Clostridium difficile

(2008) S. D. Baines et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Emerging Pathogens: Challenges and Successes of Molecular Diagnostics

(2008) Jianli Dong et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Induction of toxins in Clostridium difficile is associated with dramatic changes of its metabolism

(2008) S. Karlsson et al.   MICROBIOLOGY-SGM

A multifaceted role for polyamines in bacterial pathogens

(2008) Pratik Shah et al.   MOLECULAR MICROBIOLOGY

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY