The Anti-Sigma Factor TcdC Modulates Hypervirulence in an Epidemic BI/NAP1/027 Clinical Isolate of Clostridium difficile

Increasing Incidence of Community-Associated Atypical Clostridium difficile Disease in Children

(2010) Susan S. Baker et al.   CLINICAL PEDIATRICS

Human Hypervirulent Clostridium difficile Strains Exhibit Increased Sporulation as Well as Robust Toxin Production

(2010) M. Merrigan et al.   JOURNAL OF BACTERIOLOGY

The role of toxin A and toxin B in Clostridium difficile infection

(2010) Sarah A. Kuehne et al.   NATURE

Evolutionary dynamics of Clostridium difficile over short and long time scales

(2010) M. He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Variations in TcdB Activity and the Hypervirulence of Emerging Strains of Clostridium difficile

(2010) Jordi M. Lanis et al.   PLoS Pathogens

A mariner-Based Transposon System for In Vivo Random Mutagenesis of Clostridium difficile

(2009) S. T. Cartman et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Truncation in the tcdC region of the Clostridium difficilePathLoc of clinical isolates does not predict increased biological activity of Toxin B or Toxin A

(2009) Ruth Murray et al.   BMC INFECTIOUS DISEASES

Clostridium difficile Infection Caused by the Epidemic BI/NAP1/027 Strain

(2009) Jennifer R. O'Connor et al.   GASTROENTEROLOGY

Distinctive Profiles of Infection and Pathology in Hamsters Infected with Clostridium difficile Strains 630 and B1

(2009) D. Goulding et al.   INFECTION AND IMMUNITY

Antibiotic Treatment of Clostridium difficile Carrier Mice Triggers a Supershedder State, Spore-Mediated Transmission, and Severe Disease in Immunocompromised Hosts

(2009) T. D. Lawley et al.   INFECTION AND IMMUNITY

Clostridium difficile—A continually evolving and problematic pathogen

(2009) Lisa F. Dawson et al.   INFECTION GENETICS AND EVOLUTION

Genomic variation and evolution of Staphylococcus aureus

(2009) Jodi A. Lindsay   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

SleC Is Essential for Germination of Clostridium difficile Spores in Nutrient-Rich Medium Supplemented with the Bile Salt Taurocholate

(2009) D. A. Burns et al.   JOURNAL OF BACTERIOLOGY

Recurrent Clostridium difficile infection: A review of risk factors, treatments, and outcomes

(2009) Stuart Johnson   JOURNAL OF INFECTION

The ClosTron: Mutagenesis in Clostridium refined and streamlined

(2009) John T. Heap et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Toxin B is essential for virulence of Clostridium difficile

(2009) Dena Lyras et al.   NATURE

Clostridium difficile Toxin CDT Induces Formation of Microtubule-Based Protrusions and Increases Adherence of Bacteria

(2009) Carsten Schwan et al.   PLoS Pathogens

Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium

(2009) Richard A Stabler et al.   GENOME BIOLOGY

Clostridium difficile–associated diarrhea: an emerging threat to pregnant women

(2008) Nadine G. Rouphael et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Clostridium difficile PCR Ribotype 078: an Emerging Strain in Humans and in Pigs?

(2008) A. Goorhuis et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Increased Sporulation Rate of Epidemic Clostridium difficile Type 027/NAP1

(2008) T. Akerlund et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Comparative analysis of BI/NAP1/027 hypervirulent strains reveals novel toxin B-encoding gene (tcdB) sequences

(2008) R. A. Stabler et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Clostridium difficile toxin synthesis is negatively regulated by TcdC

(2008) B. Dupuy et al.   JOURNAL OF MEDICAL MICROBIOLOGY