Broad and direct interaction between TLR and Siglec families of pattern recognition receptors and its regulation by Neu1

Siglec-G-CD24 axis controls the severity of graft-versus-host disease in mice

(2014) T. Toubai et al.   BLOOD

DAMP Molecule S100A9 Acts as a Molecular Pattern to Enhance Inflammation during Influenza A Virus Infection: Role of DDX21-TRIF-TLR4-MyD88 Pathway

(2014) Su-Yu Tsai et al.   PLoS Pathogens

Group B Streptococcus Engages an Inhibitory Siglec through Sialic Acid Mimicry to Blunt Innate Immune and Inflammatory Responses In Vivo

(2014) Yung-Chi Chang et al.   PLoS Pathogens

Siglec-E is a negative regulator of acute pulmonary neutrophil inflammation and suppresses CD11b  2-integrin-dependent signaling

(2013) S. J. McMillan et al.   BLOOD

Induction of Siglec-G by RNA Viruses Inhibits the Innate Immune Response by Promoting RIG-I Degradation

(2013) Weilin Chen et al.   CELL

Copresentation of Antigen and Ligands of Siglec-G Induces B Cell Tolerance Independent of CD22

(2013) F. Pfrengle et al.   JOURNAL OF IMMUNOLOGY

T cell regulation mediated by interaction of soluble CD52 with the inhibitory receptor Siglec-10

(2013) Esther Bandala-Sanchez et al.   NATURE IMMUNOLOGY

Mammalian sialidases: Physiological and pathological roles in cellular functions

(2012) T. Miyagi et al.   GLYCOBIOLOGY

Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1

(2012) Petr Broz et al.   NATURE

Sensing and reacting to microbes through the inflammasomes

(2012) Luigi Franchi et al.   NATURE IMMUNOLOGY

Neu1 Sialidase and Matrix Metalloproteinase-9 Cross-talk Is Essential for Toll-like Receptor Activation and Cellular Signaling

(2011) Samar Abdulkhalek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identifying selective inhibitors against the human cytosolic sialidase NEU2 by substrate specificity studies

(2011) Yanhong Li et al.   Molecular BioSystems

Amelioration of sepsis by inhibiting sialidase-mediated disruption of the CD24-SiglecG interaction

(2011) Guo-Yun Chen et al.   NATURE BIOTECHNOLOGY

A Method to Separate Nuclear, Cytosolic, and Membrane-Associated Signaling Molecules in Cultured Cells

(2011) X. Liu et al.   Science Signaling

CD22 x Siglec-G Double-Deficient Mice Have Massively Increased B1 Cell Numbers and Develop Systemic Autoimmunity

(2010) J. Jellusova et al.   JOURNAL OF IMMUNOLOGY

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Neu1 desialylation of sialyl α-2,3-linked β-galactosyl residues of TOLL-like receptor 4 is essential for receptor activation and cellular signaling

(2009) Schammim Ray Amith et al.   CELLULAR SIGNALLING

Dependence of pathogen molecule-induced Toll-like receptor activation and cell function on Neu1 sialidase

(2009) Schammim Ray Amith et al.   GLYCOCONJUGATE JOURNAL

Decoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and induce B cell tolerance in vivo

(2009) Bao Hoa Duong et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Siglec-E Is Up-Regulated and Phosphorylated Following Lipopolysaccharide Stimulation in Order to Limit TLR-Driven Cytokine Production

(2009) C. R. Boyd et al.   JOURNAL OF IMMUNOLOGY

CD24 and Siglec-10 Selectively Repress Tissue Damage-Induced Immune Responses

(2009) G.-Y. Chen et al.   SCIENCE

CD24-Siglec G/10 discriminates danger- from pathogen-associated molecular patterns

(2009) Yang Liu et al.   TRENDS IN IMMUNOLOGY

Pasteurella multocida sialic acid aldolase: a promising biocatalyst

(2008) Yanhong Li et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Modulated Inflammation by Injection of High-Mobility Group Box 1 Recovers Post-Infarction Chronically Failing Heart

(2008) K. Takahashi et al.   CIRCULATION

TSC–mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species

(2008) Chong Chen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The S100A8–serum amyloid A3–TLR4 paracrine cascade establishes a pre-metastatic phase

(2008) Sachie Hiratsuka et al.   NATURE CELL BIOLOGY