A component of the mir-17-92 polycistronic oncomir promotes oncogene-dependent apoptosis

Tumor suppressor functions of FBW7 in cancer development and progression

(2012) Zhiwei Wang et al.   FEBS LETTERS

Fbw7 and p53 Cooperatively Suppress Advanced and Chromosomally Unstable Intestinal Cancer

(2012) J. E. Grim et al.   MOLECULAR AND CELLULAR BIOLOGY

Synthetic lethality between Rb, p53 and Dicer or miR-17–92 in retinal progenitors suppresses retinoblastoma formation

(2012) David Nittner et al.   NATURE CELL BIOLOGY

Two sides of the Myc-induced DNA damage response: from tumor suppression to tumor maintenance

(2012) Stefano Campaner et al.   Cell Division

miR-92 is a key oncogenic component of the miR-17-92 cluster in colon cancer

(2011) Akihiko Tsuchida et al.   CANCER SCIENCE

Limiting Ago protein restricts RNAi and microRNA biogenesis during early development in Xenopus laevis

(2011) E. Lund et al.   GENES & DEVELOPMENT

miR-17 92 cooperates with RB pathway mutations to promote retinoblastoma

(2011) K. Conkrite et al.   GENES & DEVELOPMENT

A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL)

(2011) Konstantinos J Mavrakis et al.   NATURE GENETICS

The miR-17-92 Cluster of MicroRNAs Confers Tumorigenicity by Inhibiting Oncogene-Induced Senescence

(2010) L. Hong et al.   CANCER RESEARCH

MicroRNA-223 Regulates Cyclin E Activity by Modulating Expression of F-box and WD-40 Domain Protein 7

(2010) Yanfei Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia

(2010) Konstantinos J. Mavrakis et al.   NATURE CELL BIOLOGY

The ubiquitous nature of cancer: the role of the SCFFbw7 complex in development and transformation

(2010) K M Crusio et al.   ONCOGENE

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

microRNA-24a is required to repress apoptosis in the developing neural retina

(2009) J. C. Walker et al.   GENES & DEVELOPMENT

Genetic dissection of the miR-17 92 cluster of microRNAs in Myc-induced B-cell lymphomas

(2009) P. Mu et al.   GENES & DEVELOPMENT

miR-19 is a key oncogenic component of mir-17-92

(2009) V. Olive et al.   GENES & DEVELOPMENT

Biogenesis of small RNAs in animals

(2009) V. Narry Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

ThemiR-17∼92cluster collaborates with the Sonic Hedgehog pathway in medulloblastoma

(2009) Tamar Uziel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct Thresholds Govern Myc's Biological Output In Vivo

(2008) Daniel J. Murphy et al.   CANCER CELL

miRiad Roles for the miR-17-92 Cluster in Development and Disease

(2008) Joshua T. Mendell   CELL

Cyclin E phosphorylation regulates cell proliferation in hematopoietic and epithelial lineages in vivo

(2008) A. C. Minella et al.   GENES & DEVELOPMENT

Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL

(2008) S. Matsuoka et al.   GENES & DEVELOPMENT

Isoform- and cell cycle–dependent substrate degradation by the Fbw7 ubiquitin ligase

(2008) Jonathan E. Grim et al.   JOURNAL OF CELL BIOLOGY

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

(2008) Witold Filipowicz et al.   NATURE REVIEWS GENETICS