Synthetic lethality between Rb, p53 and Dicer or miR-17–92 in retinal progenitors suppresses retinoblastoma formation

Cooperation between Rb and Arf in suppressing mouse retinoblastoma

(2012) Karina Conkrite et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeting the p53 Pathway in Retinoblastoma with Subconjunctival Nutlin-3a

(2011) R. C. Brennan et al.   CANCER RESEARCH

Searching for synthetic lethality in cancer

(2011) Rachel Brough et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

miR-17 92 cooperates with RB pathway mutations to promote retinoblastoma

(2011) K. Conkrite et al.   GENES & DEVELOPMENT

MicroRNA-processing Enzyme Dicer Is Required in Epicardium for Coronary Vasculature Development

(2011) Manvendra K. Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA Biogenesis Is Required for Myc-Induced B-Cell Lymphoma Development and Survival

(2010) M. P. Arrate et al.   CANCER RESEARCH

Tumorigenicity of the miR-17-92 cluster distilled

(2010) G. van Haaften et al.   GENES & DEVELOPMENT

Dicer Is Required for the Transition from Early to Late Progenitor State in the Developing Mouse Retina

(2010) S. A. Georgi et al.   JOURNAL OF NEUROSCIENCE

Perturbations of MicroRNA Function in Mouse Dicer Mutants Produce Retinal Defects and Lead to Aberrant Axon Pathfinding at the Optic Chiasm

(2010) Rita Pinter et al.   PLoS One

Retinoblastoma Has Properties of a Cone Precursor Tumor and Depends Upon Cone-Specific MDM2 Signaling

(2009) Xiaoliang L. Xu et al.   CELL

Monoallelic but not biallelic loss of Dicer1 promotes tumorigenesis in vivo

(2009) I Lambertz et al.   CELL DEATH AND DIFFERENTIATION

Down-regulation of dicer expression in ovarian cancer tissues

(2009) Georgios Pampalakis et al.   CLINICAL BIOCHEMISTRY

Repression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosis

(2009) Hong-li Yan et al.   EMBO JOURNAL

Dicer1 functions as a haploinsufficient tumor suppressor

(2009) M. S. Kumar et al.   GENES & DEVELOPMENT

A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function

(2009) Sonia A Melo et al.   NATURE GENETICS

RDML: structured language and reporting guidelines for real-time quantitative PCR data

(2009) S. Lefever et al.   NUCLEIC ACIDS RESEARCH

DICER1 Mutations in Familial Pleuropulmonary Blastoma

(2009) D. A. Hill et al.   SCIENCE

A novel and universal method for microRNA RT-qPCR data normalization

(2009) Pieter Mestdagh et al.   GENOME BIOLOGY

Targeted Deletion Reveals Essential and Overlapping Functions of the miR-17∼92 Family of miRNA Clusters

(2008) Andrea Ventura et al.   CELL

Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells

(2008) Rajini Mudhasani et al.   JOURNAL OF CELL BIOLOGY

Dicer Inactivation Leads to Progressive Functional and Structural Degeneration of the Mouse Retina

(2008) D. Damiani et al.   JOURNAL OF NEUROSCIENCE

High-throughput stem-loop RT-qPCR miRNA expression profiling using minute amounts of input RNA

(2008) Pieter Mestdagh et al.   NUCLEIC ACIDS RESEARCH

MicroRNA regulation of a cancer network: Consequences of the feedback loops involving miR-17-92, E2F, and Myc

(2008) B. D. Aguda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA