New Insights in the Mobilization of Hematopoietic Stem Cells in Lymphoma and Multiple Myeloma Patients

Osteal Tissue Macrophages Are Intercalated throughout Human and Mouse Bone Lining Tissues and Regulate Osteoblast Function In Vitro and In Vivo

(2014) M. K. Chang et al.   JOURNAL OF IMMUNOLOGY

Overcoming the Response Plateau in Multiple Myeloma: A Novel Bortezomib-Based Strategy for Secondary Induction and High-Yield CD34+ Stem Cell Mobilization

(2013) R. Niesvizky et al.   CLINICAL CANCER RESEARCH

The High-Affinity CXCR4 Antagonist BKT140 Is Safe and Induces a Robust Mobilization of Human CD34+ Cells in Patients with Multiple Myeloma

(2013) A. Peled et al.   CLINICAL CANCER RESEARCH

Characterization of peripheral blood stem cell grafts mobilized by granulocyte colony-stimulating factor and plerixafor compared with granulocyte colony-stimulating factor alone

(2013) Beatrice Gaugler et al.   CYTOTHERAPY

Role of key regulators of the cell cycle in maintenance of hematopoietic stem cells

(2012) Akinobu Matsumoto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

S1P promotes murine progenitor cell egress and mobilization via S1P1-mediated ROS signaling and SDF-1 release

(2012) K. Golan et al.   BLOOD

Hematopoietic stem cells: to be or Notch to be

(2012) A. Bigas et al.   BLOOD

Norepinephrine reuptake inhibition promotes mobilization in mice: potential impact to rescue low stem cell yields

(2012) D. Lucas et al.   BLOOD

Blood graft composition after plerixafor injection in patients with NHL

(2012) Ville Varmavuo et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

The Plasminogen System in Regulating Stem Cell Mobilization

(2012) Yanqing Gong et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Hematopoietic stem cell mobilization: updated conceptual renditions

(2012) H Bonig et al.   LEUKEMIA

A specific time course for mobilization of peripheral blood CD34+ cells after plerixafor injection in very poor mobilizer patients: impact on the timing of the apheresis procedure

(2012) François Lefrère et al.   TRANSFUSION

Sphingosine-1-phosphate facilitates trafficking of hematopoietic stem cells and their mobilization by CXCR4 antagonists in mice

(2011) J. G. Juarez et al.   BLOOD

How I treat patients who mobilize hematopoietic stem cells poorly

(2011) L. B. To et al.   BLOOD

Proposed definition of ‘poor mobilizer’ in lymphoma and multiple myeloma: an analytic hierarchy process by ad hoc working group Gruppo ItalianoTrapianto di Midollo Osseo

(2011) A Olivieri et al.   BONE MARROW TRANSPLANTATION

Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche

(2011) Toshio Suda et al.   Cell Stem Cell

CD45 regulates homing and engraftment of immature normal and leukemic human cells in transplanted immunodeficient mice

(2011) Shoham Shivtiel et al.   EXPERIMENTAL HEMATOLOGY

Maintenance of genomic integrity in hematopoietic stem cells

(2011) Kazuhito Naka et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

A novel perspective on stem cell homing and mobilization: review on bioactive lipids as potent chemoattractants and cationic peptides as underappreciated modulators of responsiveness to SDF-1 gradients

(2011) M Z Ratajczak et al.   LEUKEMIA

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Role of Cripto-1 in Stem Cell Maintenance and Malignant Progression

(2010) Caterina Bianco et al.   AMERICAN JOURNAL OF PATHOLOGY

Enhanced c-Met activity promotes G-CSF-induced mobilization of hematopoietic progenitor cells via ROS signaling

(2010) M. Tesio et al.   BLOOD

Role for vitamin D receptor in the neuronal control of the hematopoietic stem cell niche

(2010) Y. Kawamori et al.   BLOOD

Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs

(2010) I. G. Winkler et al.   BLOOD

Positioning of bone marrow hematopoietic and stromal cells relative to blood flow in vivo: serially reconstituting hematopoietic stem cells reside in distinct nonperfused niches

(2010) I. G. Winkler et al.   BLOOD

Development and validation of a decision-making algorithm to guide the use of plerixafor for autologous hematopoietic stem cell mobilization

(2010) L J Costa et al.   BONE MARROW TRANSPLANTATION

CD49d blockade by natalizumab in patients with multiple sclerosis affects steady-state hematopoiesis and mobilizes progenitors with a distinct phenotype and function

(2010) D Jing et al.   BONE MARROW TRANSPLANTATION

Impact of constitutional polymorphisms in VCAM1 and CD44 on CD34+ cell collection yield after administration of granulocyte colony-stimulating factor to healthy donors

(2010) B. Martin-Antonio et al.   HAEMATOLOGICA

Eicosanoid regulation of hematopoiesis and hematopoietic stem and progenitor trafficking

(2010) J Hoggatt et al.   LEUKEMIA

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

(2010) D. F. Egan et al.   SCIENCE

Treatment with Plerixafor in non-Hodgkin's Lymphoma and Multiple Myeloma Patients to Increase the Number of Peripheral Blood Stem Cells When Given a Mobilizing Regimen of G-CSF: Implications for the Heavily Pretreated Patient

(2009) Patrick Stiff et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Poor Mobilization of Hematopoietic Stem Cells—Definitions, Incidence, Risk Factors, and Impact on Outcome of Autologous Transplantation

(2009) Patrick Wuchter et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Prostaglandin E2 enhances hematopoietic stem cell homing, survival, and proliferation

(2009) J. Hoggatt et al.   BLOOD

Plerixafor (AMD3100) and granulocyte colony-stimulating factor (G-CSF) mobilize different CD34+ cell populations based on global gene and microRNA expression signatures

(2009) R. E. Donahue et al.   BLOOD

Plerixafor and G-CSF versus placebo and G-CSF to mobilize hematopoietic stem cells for autologous stem cell transplantation in patients with multiple myeloma

(2009) J. F. DiPersio et al.   BLOOD

Suppression of CXCL12 production by bone marrow osteoblasts is a common and critical pathway for cytokine-induced mobilization

(2009) M. J. Christopher et al.   BLOOD

Rescue from failed growth factor and/or chemotherapy HSC mobilization with G-CSF and plerixafor (AMD3100): an institutional experience

(2009) C J Fowler et al.   BONE MARROW TRANSPLANTATION

MT1-MMP and RECK are involved in human CD34+ progenitor cell retention, egress, and mobilization

(2009) Yaron Vagima et al.   JOURNAL OF CLINICAL INVESTIGATION

Phase III Prospective Randomized Double-Blind Placebo-Controlled Trial of Plerixafor Plus Granulocyte Colony-Stimulating Factor Compared With Placebo Plus Granulocyte Colony-Stimulating Factor for Autologous Stem-Cell Mobilization and Transplantation for Patients With Non-Hodgkin's Lymphoma

(2009) John F. DiPersio et al.   JOURNAL OF CLINICAL ONCOLOGY

Concurrent Blockade of α4-Integrin and CXCR4 in Hematopoietic Stem/Progenitor Cell Mobilization

(2009) Halvard Bonig et al.   STEM CELLS

Impact of Mobilization and Remobilization Strategies on Achieving Sufficient Stem Cell Yields for Autologous Transplantation

(2008) Iskra Pusic et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

A Phase II Study of Plerixafor (AMD3100) plus G-CSF for Autologous Hematopoietic Progenitor Cell Mobilization in Patients with Hodgkin Lymphoma

(2008) Amanda Cashen et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Heparanase regulates retention and proliferation of primitive Sca-1+/c-Kit+/Lin- cells via modulation of the bone marrow microenvironment

(2008) A. Spiegel et al.   BLOOD

The monoclonal anti-VLA-4 antibody natalizumab mobilizes CD34+ hematopoietic progenitor cells in humans

(2008) F. Zohren et al.   BLOOD

Heme oxygenase-1 deficiency leads to disrupted response to acute stress in stem cells and progenitors

(2008) Y.-A. Cao et al.   BLOOD

Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair

(2008) Anne Wilson et al.   CELL

Parathyroid hormone effectively induces mobilization of progenitor cells without depletion of bone marrow

(2008) Stefan Brunner et al.   EXPERIMENTAL HEMATOLOGY

CD45 regulates retention, motility, and numbers of hematopoietic progenitors, and affects osteoclast remodeling of metaphyseal trabecules

(2008) Shoham Shivtiel et al.   JOURNAL OF EXPERIMENTAL MEDICINE