Sphingosine-1-phosphate facilitates trafficking of hematopoietic stem cells and their mobilization by CXCR4 antagonists in mice

Prolonged Exposure to Sphingosine 1–Phosphate Receptor-1 Agonists Exacerbates Vascular Leak, Fibrosis, and Mortality after Lung Injury

(2010) Barry S. Shea et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Update on clinical experience with AMD3100, an SDF-1/CXCL12–CXCR4 inhibitor, in mobilization of hematopoietic stem and progenitor cells

(2010) Iskra Pusic et al.   CURRENT OPINION IN HEMATOLOGY

S1P1 receptor directs the release of immature B cells from bone marrow into blood

(2010) Maria L. Allende et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Novel insight into stem cell mobilization-Plasma sphingosine-1-phosphate is a major chemoattractant that directs the egress of hematopoietic stem progenitor cells from the bone marrow and its level in peripheral blood increases during mobilization due to activation of complement cascade/membrane attack complex

(2010) M Z Ratajczak et al.   LEUKEMIA

Sphingosine 1-Phosphate (S1P) Regulates Vascular Contraction via S1P3 Receptor: Investigation Based on a New S1P3 Receptor Antagonist

(2010) A. Murakami et al.   MOLECULAR PHARMACOLOGY

A Placebo-Controlled Trial of Oral Fingolimod in Relapsing Multiple Sclerosis

(2010) Ludwig Kappos et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sphingosine-1-Phosphate Mediates Proliferation Maintaining the Multipotency of Human Adult Bone Marrow and Adipose Tissue-derived Stem Cells

(2010) X. He et al.   Journal of Molecular Cell Biology

The AMD3100 story: The path to the discovery of a stem cell mobilizer (Mozobil)

(2009) Erik De Clercq   BIOCHEMICAL PHARMACOLOGY

Vascular Endothelium As a Contributor of Plasma Sphingosine 1-Phosphate

(2008) Krishnan Venkataraman et al.   CIRCULATION RESEARCH

Evolving concepts on the microenvironmental niche for hematopoietic stem cells

(2008) Marc HGP Raaijmakers et al.   CURRENT OPINION IN HEMATOLOGY

Mobilization of hematopoietic stem cells: state of the art

(2008) Jean-Pierre Levesque et al.   Current Opinion in Organ Transplantation

Eukaryotic Elongation Factor 1A Interacts with Sphingosine Kinase and Directly Enhances Its Catalytic Activity

(2008) Tamara M. Leclercq et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of CD44, but not CD44v6, predicts relapse in children with B cell progenitor acute lymphoblastic leukemia lacking adverse or favorable genetics

(2008) Naveed I. Khan et al.   LEUKEMIA & LYMPHOMA

S1P1 overexpression stimulates S1P-dependent chemotaxis of human CD34+ hematopoietic progenitor cells but strongly inhibits SDF-1/CXCR4-dependent migration and in vivo homing

(2008) Martin F. Ryser et al.   MOLECULAR IMMUNOLOGY

Haematopoietic stem cell release is regulated by circadian oscillations

(2008) Simón Méndez-Ferrer et al.   NATURE

Granulocyte Colony–Stimulating Factor Administration: Adverse Events

(2008) Anita D'Souza et al.   TRANSFUSION MEDICINE REVIEWS