Cerebral malaria: why experimental murine models are required to understand the pathogenesis of disease

Cutting Edge: Selective Blockade of LIGHT-Lymphotoxin   Receptor Signaling Protects Mice from Experimental Cerebral Malaria Caused by Plasmodium berghei ANKA

(2014) L. M. Randall et al.   JOURNAL OF IMMUNOLOGY

Malaria-Specific and Nonspecific Activation of CD8+ T Cells during Blood Stage of Plasmodium berghei Infection

(2014) M. Miyakoda et al.   JOURNAL OF IMMUNOLOGY

Chemokine Gene Expression during Fatal Murine Cerebral Malaria and Protection Due to CXCR3 Deficiency

(2014) J. Miu et al.   JOURNAL OF IMMUNOLOGY

Plasmodium falciparum-infected erythrocytes induce NF- B regulated inflammatory pathways in human cerebral endothelium

(2009) A. K. Tripathi et al.   BLOOD

Advances in the management of cerebral malaria in adults

(2009) Saroj K Mishra et al.   CURRENT OPINION IN NEUROLOGY

Platelet microparticles: a new player in malaria parasite cytoadherence to human brain endothelium

(2009) Dorothée Faille et al.   FASEB JOURNAL

Behavior of Parasite-Specific Effector CD8+ T Cells in the Brain and Visualization of a Kinesis-Associated System of Reticular Fibers

(2009) Emma H. Wilson et al.   IMMUNITY

Dynamic Imaging of T Cell-Parasite Interactions in the Brains of Mice Chronically Infected with Toxoplasma gondii

(2009) Marie Schaeffer et al.   JOURNAL OF IMMUNOLOGY

Tumor Necrosis Factor and Lymphotoxin‐α Polymorphisms and Severe Malaria in African Populations

(2009) Taane G. Clark et al.   JOURNAL OF INFECTIOUS DISEASES

Genetics of susceptibility toPlasmodium falciparum: from classical malaria resistance genes towards genome-wide association studies

(2009) F. VERRA et al.   PARASITE IMMUNOLOGY

Lack of Association of Interferon Regulatory Factor 1 with Severe Malaria in Affected Child-Parental Trio Studies across Three African Populations

(2009) Valentina D. Mangano et al.   PLoS One

Retinal Pathology of Pediatric Cerebral Malaria in Malawi

(2009) Valerie A. White et al.   PLoS One

High Throughput Functional Assays of the Variant Antigen PfEMP1 Reveal a Single Domain in the 3D7 Plasmodium falciparum Genome that Binds ICAM1 with High Affinity and Is Targeted by Naturally Acquired Neutralizing Antibodies

(2009) Andrew V. Oleinikov et al.   PLoS Pathogens

Distinct Roles for FOXP3+ and FOXP3− CD4+ T Cells in Regulating Cellular Immunity to Uncomplicated and Severe Plasmodium falciparum Malaria

(2009) Michael Walther et al.   PLoS Pathogens

IP-10-Mediated T Cell Homing Promotes Cerebral Inflammation over Splenic Immunity to Malaria Infection

(2009) Catherine Q. Nie et al.   PLoS Pathogens

Antigenic Variation in Plasmodium falciparum

(2008) Artur Scherf et al.   Annual Review of Microbiology

Host response to cytoadherence inPlasmodium falciparum

(2008) Srabasti J. Chakravorty et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Platelet Factor 4 Mediates Inflammation in Experimental Cerebral Malaria

(2008) Kalyan Srivastava et al.   Cell Host & Microbe

CXCR3 determines strain susceptibility to murine cerebral malaria by mediating T lymphocyte migration toward IFN-γ-induced chemokines

(2008) Philippe E. Van den Steen et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Variation in the ICAM1 gene is not associated with severe malaria phenotypes

(2008) A E Fry et al.   GENES AND IMMUNITY

Interferon regulatory factor-1 polymorphisms are associated with the control of Plasmodium falciparum infection

(2008) V D Mangano et al.   GENES AND IMMUNITY

Host Biomarkers and Biological Pathways That Are Associated with the Expression of Experimental Cerebral Malaria in Mice

(2008) M. S. Oakley et al.   INFECTION AND IMMUNITY

Common Strategies To Prevent and Modulate Experimental Cerebral Malaria in Mouse Strains with Different Susceptibilities

(2008) L. M. Randall et al.   INFECTION AND IMMUNITY

Inhibition of histamine-mediated signaling confers significant protection against severe malaria in mouse models of disease

(2008) Walid Beghdadi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Recovery of Endothelial Function in Severe Falciparum Malaria: Relationship with Improvement in Plasmal‐Arginine and Blood Lactate Concentrations

(2008) Tsin W. Yeo et al.   JOURNAL OF INFECTIOUS DISEASES

Cognitive Dysfunction in Mice Infected withPlasmodium bergheiStrain ANKA

(2008) Mahalia S. Desruisseaux et al.   JOURNAL OF INFECTIOUS DISEASES

Imaging T-cell movement in the brain during experimental cerebral malaria

(2008) F. ORTOLANO et al.   PARASITE IMMUNOLOGY

Control of pathogenic CD8+T cell migration to the brain by IFN-γ during experimental cerebral malaria

(2008) E. BELNOUE et al.   PARASITE IMMUNOLOGY

Both Functional LTβ Receptor and TNF Receptor 2 Are Required for the Development of Experimental Cerebral Malaria

(2008) Dieudonnée Togbe et al.   PLoS One

Blood-stage Plasmodium infection induces CD8+ T lymphocytes to parasite-expressed antigens, largely regulated by CD8 + dendritic cells

(2008) R. J. Lundie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High levels of erythropoietin are associated with protection against neurological sequelae in African children with cerebral malaria

(2008) C. Casals-Pascual et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chemokine receptor CXCR3 and its ligands CXCL9 and CXCL10 are required for the development of murine cerebral malaria

(2008) G. S. V. Campanella et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Can erythropoietin be used to prevent brain damage in cerebral malaria?

(2008) Climent Casals-Pascual et al.   TRENDS IN PARASITOLOGY

IL-10 from CD4+CD25−Foxp3−CD127− Adaptive Regulatory T Cells Modulates Parasite Clearance and Pathology during Malaria Infection

(2008) Kevin N. Couper et al.   PLoS Pathogens

Parasite Burden and CD36-Mediated Sequestration Are Determinants of Acute Lung Injury in an Experimental Malaria Model

(2008) Fiona E. Lovegrove et al.   PLoS Pathogens