Channel-Forming Bacterial Toxins in Biosensing and Macromolecule Delivery

Advances in Anticancer Antibody-Drug Conjugates and Immunotoxins

(2015) Franco Dosio et al.   Recent Patents on Anti-Cancer Drug Discovery

Alpha-Synuclein Lipid-Dependent Membrane Binding and Translocation through the α-Hemolysin Channel

(2014) Philip A. Gurnev et al.   BIOPHYSICAL JOURNAL

Designing inhibitors of anthrax toxin

(2014) Ekaterina M Nestorovich et al.   Expert Opinion on Drug Discovery

The investigation of epsilon toxin effects on different cancerous cell lines and its synergism effect with methotrexate

(2014) Sadegh Hasannia et al.   Journal of Cancer Research and Therapeutics

Polymer capture by α-hemolysin pore upon salt concentration gradient

(2014) Byoung-jin Jeon et al.   JOURNAL OF CHEMICAL PHYSICS

Single-molecule site-specific detection of protein phosphorylation with a nanopore

(2014) Christian B Rosen et al.   NATURE BIOTECHNOLOGY

Functional truncated membrane pores

(2014) D. Stoddart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytolethal distending toxin B as a cell-killing component of tumor-targeted anthrax toxin fusion proteins

(2014) C Bachran et al.   Cell Death & Disease

Slowing down single-molecule trafficking through a protein nanopore reveals intermediates for peptide translocation

(2014) Loredana Mereuta et al.   Scientific Reports

Reductive Methylation and Mutation of an Anthrax Toxin Fusion Protein Modulates its Stability and Cytotoxicity

(2014) Christopher Bachran et al.   Scientific Reports

Analysis of a Single α-Synuclein Fibrillation by the Interaction with a Protein Nanopore

(2013) Hai-Yan Wang et al.   ANALYTICAL CHEMISTRY

Electrophysiology of Bacteria

(2013) Anne H. Delcour   Annual Review of Microbiology

Lipid and phase specificity of α-toxin from S. aureus

(2013) M. Schwiering et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

C2-Streptavidin Mediates the Delivery of Biotin-Conjugated Tumor Suppressor Protein P53 into Tumor Cells

(2013) Jörg Fahrer et al.   BIOCONJUGATE CHEMISTRY

Rates and Stoichiometries of Metal Ion Probes of Cysteine Residues within Ion Channels

(2013) Lai-Sheung Choi et al.   BIOPHYSICAL JOURNAL

Cationic Cell-Penetrating Peptide Binds to Planar Lipid Bilayers Containing Negatively Charged Lipids but does not Induce Conductive Pores

(2013) Philip A. Gurnev et al.   BIOPHYSICAL JOURNAL

Cyclodextrin derivatives as anti-infectives

(2013) Vladimir A Karginov   CURRENT OPINION IN PHARMACOLOGY

Cathepsin B as a cancer target

(2013) Christopher S Gondi et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

LukS-PV induces mitochondrial-mediated apoptosis and G0/G1 cell cycle arrest in human acute myeloid leukemia THP-1 cells

(2013) Su Bu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Engineering Anthrax Toxin Variants That Exclusively Form Octamers and Their Application to Targeting Tumors

(2013) Damilola D. Phillips et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutants of listeriolysin O for enhanced liposomal delivery of macromolecules

(2013) Zachary F. Walls et al.   JOURNAL OF BIOTECHNOLOGY

Anthrax toxin-induced rupture of artificial lipid bilayer membranes

(2013) Brian J. Nablo et al.   JOURNAL OF CHEMICAL PHYSICS

Diphtheria toxin-based targeted toxin therapy for brain tumors

(2013) Yan Michael Li et al.   JOURNAL OF NEURO-ONCOLOGY

pH Responsive Janus-like Supramolecular Fusion Proteins for Functional Protein Delivery

(2013) Seah Ling Kuan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Role of Pore-Forming Toxins in Bacterial Infectious Diseases

(2013) F. C. O. Los et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Receptor-Directed Chimeric Toxins Created by Sortase-Mediated Protein Fusion

(2013) A. J. McCluskey et al.   MOLECULAR CANCER THERAPEUTICS

Nanopore-Based Identification of Individual Nucleotides for Direct RNA Sequencing

(2013) Mariam Ayub et al.   NANO LETTERS

Key tissue targets responsible for anthrax-toxin-induced lethality

(2013) Shihui Liu et al.   NATURE

Unfoldase-mediated protein translocation through an α-hemolysin nanopore

(2013) Jeff Nivala et al.   NATURE BIOTECHNOLOGY

Molecular assembly of the aerolysin pore reveals a swirling membrane-insertion mechanism

(2013) Matteo T Degiacomi et al.   Nature Chemical Biology

Multistep protein unfolding during nanopore translocation

(2013) David Rodriguez-Larrea et al.   Nature Nanotechnology

Designed Azolopyridinium Salts Block Protective Antigen Pores In Vitro and Protect Cells from Anthrax Toxin

(2013) Christoph Beitzinger et al.   PLoS One

A Cell-Permeable Fusion Protein Based on Clostridium botulinum C2 Toxin for Delivery of p53 Tumorsuppressor into Cancer Cells

(2013) Jörg Fahrer et al.   PLoS One

Anthrax Toxin-Mediated Delivery of the Pseudomonas Exotoxin A Enzymatic Domain to the Cytosol of Tumor Cells via Cleavable Ubiquitin Fusions

(2013) C. Bachran et al.   mBio

An engineered dimeric protein pore that spans adjacent lipid bilayers

(2013) Shiksha Mantri et al.   Nature Communications

Clostridium perfringens Epsilon Toxin: A Malevolent Molecule for Animals and Man?

(2013) Bradley Stiles et al.   Toxins

Staphylococcus aureus α-Toxin: Nearly a Century of Intrigue

(2013) Bryan Berube et al.   Toxins

Immunotoxins: The Role of the Toxin

(2013) Antonella Antignani et al.   Toxins

Wild Type, Mutant Protein Unfolding and Phase Transition Detected by Single-Nanopore Recording

(2012) Céline Merstorf et al.   ACS Chemical Biology

Probing DNA–Lipid Membrane Interactions with a Lipopeptide Nanopore

(2012) Andrey Bessonov et al.   ACS Nano

Single Molecule Detection of Glycosaminoglycan Hyaluronic Acid Oligosaccharides and Depolymerization Enzyme Activity Using a Protein Nanopore

(2012) Aziz Fennouri et al.   ACS Nano

Thermal Unfolding of Proteins Probed at the Single Molecule Level Using Nanopores

(2012) Linda Payet et al.   ANALYTICAL CHEMISTRY

Interactions of High-Affinity Cationic Blockers with the Translocation Pores of B. anthracis, C. botulinum, and C. perfringens Binary Toxins

(2012) Sergey M. Bezrukov et al.   BIOPHYSICAL JOURNAL

Obstructing Toxin Pathways by Targeted Pore Blockage

(2012) Ekaterina M. Nestorovich et al.   CHEMICAL REVIEWS

Disease Detection and Management via Single Nanopore-Based Sensors

(2012) Joseph E. Reiner et al.   CHEMICAL REVIEWS

Recent trends in nanopores for biotechnology

(2012) Daniel H Stoloff et al.   CURRENT OPINION IN BIOTECHNOLOGY

Bacteria and their Toxins Tamed for Immunotherapy

(2012) Irena Adkins et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

An overview of anthrax infection including the recently identified form of disease in injection drug users

(2012) Caitlin W. Hicks et al.   INTENSIVE CARE MEDICINE

Tumor therapy with a urokinase plasminogen activator-activated anthrax lethal toxin alone and in combination with paclitaxel

(2012) Alexander N. Wein et al.   INVESTIGATIONAL NEW DRUGS

Bacillus thuringiensis Parasporal Proteins Induce Cell-Cycle Arrest and Caspase-Dependant Apoptotic Cell Death in Leukemic Cells

(2012) KoK-Keong Chan et al.   JOURNAL OF ENVIRONMENTAL PATHOLOGY TOXICOLOGY AND ONCOLOGY

Protein Detection by Nanopores Equipped with Aptamers

(2012) Dvir Rotem et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Inversion of Membrane Surface Charge by Trivalent Cations Probed with a Cation-Selective Channel

(2012) Philip A. Gurnev et al.   LANGMUIR

Targeting HER2-positive cancer cells with receptor-redirected anthrax protective antigen

(2012) Andrew J. McCluskey et al.   Molecular Oncology

Rapid induction of inflammatory lipid mediators by the inflammasome in vivo

(2012) Jakob von Moltke et al.   NATURE

Automated forward and reverse ratcheting of DNA in a nanopore at 5-Å precision

(2012) Gerald M Cherf et al.   NATURE BIOTECHNOLOGY

Nanopores: A journey towards DNA sequencing

(2012) Meni Wanunu   Physics of Life Reviews

Role of N-Terminal His6-Tags in Binding and Efficient Translocation of Polypeptides into Cells Using Anthrax Protective Antigen (PA)

(2012) Christoph Beitzinger et al.   PLoS One

Nanopore analysis

(2012) Claudia A. Madampage et al.   Prion

Kinetics and thermodynamics of binding reactions as exemplified by anthrax toxin channel blockage with a cationic cyclodextrin derivative

(2012) E. M. Nestorovich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ratcheting up protein translocation with anthrax toxin

(2012) Geoffrey K. Feld et al.   PROTEIN SCIENCE

Changing the Receptor Specificity of Anthrax Toxin

(2012) A. Mechaly et al.   mBio

Anthrax Lethal Factor Cleavage of Nlrp1 Is Required for Activation of the Inflammasome

(2012) Jonathan L. Levinsohn et al.   PLoS Pathogens

Cellular and Physiological Effects of Anthrax Exotoxin and Its Relevance to Disease

(2012) David E. Lowe et al.   Frontiers in Cellular and Infection Microbiology

Noninvasive Imaging Technologies Reveal Edema Toxin as a Key Virulence Factor in Anthrax

(2011) Fabien Dumetz et al.   AMERICAN JOURNAL OF PATHOLOGY

Anthrax Infection

(2011) Daniel A. Sweeney et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Natural and artificial ion channels for biosensing platforms

(2011) L. Steller et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Nanopore Analysis of β-Amyloid Peptide Aggregation Transition Induced by Small Molecules

(2011) Hai-Yan Wang et al.   ANALYTICAL CHEMISTRY

Chemical Dissection of Protein Translocation through the Anthrax Toxin Pore

(2011) Brad L. Pentelute et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Symmetry Requirements for Effective Blocking of Pore-Forming Toxins: Comparative Study with α-, β-, and γ-Cyclodextrin Derivatives

(2011) Konstantina Yannakopoulou et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Discrimination of neutral oligosaccharides through a nanopore

(2011) Laurent Bacri et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Permeation of Styryl Dyes through Nanometer-Scale Pores in Membranes

(2011) Yao Wu et al.   BIOCHEMISTRY

Therapeutic potential of anticancer immunotoxins

(2011) Swati Choudhary et al.   DRUG DISCOVERY TODAY

The pH-dependent induction of lipid membrane ionic permeability by N-terminally lysine-substituted analogs of gramicidin A

(2011) Tatyana I. Rokitskaya et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

A guide to taming a toxin - recombinant immunotoxins constructed from Pseudomonas exotoxin A for the treatment of cancer

(2011) John E. Weldon et al.   FEBS Journal

Molecular basis of toxicity of Clostridium perfringens epsilon toxin

(2011) Monika Bokori-Brown et al.   FEBS Journal

Epsilon toxin: a fascinating pore-forming toxin

(2011) Michel R. Popoff   FEBS Journal

Web interface for brownian dynamics simulation of ion transport and its applications to beta-barrel pores

(2011) Kyu Il Lee et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Trapping a translocating protein within the anthrax toxin channel: implications for the secondary structure of permeating proteins

(2011) Daniel Basilio et al.   JOURNAL OF GENERAL PHYSIOLOGY

A kinetic analysis of protein transport through the anthrax toxin channel

(2011) Daniel Basilio et al.   JOURNAL OF GENERAL PHYSIOLOGY

Domain Flexibility Modulates the Heterogeneous Assembly Mechanism of Anthrax Toxin Protective Antigen

(2011) Geoffrey K. Feld et al.   JOURNAL OF MOLECULAR BIOLOGY

The Kinetics of Ampicillin Complexation by γ-Cyclodextrins. A Single Molecule Approach

(2011) Alina Asandei et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Tuning the Cavity of Cyclodextrins: Altered Sugar Adaptors in Protein Pores

(2011) Wen-Wu Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dynamics of Unfolded Protein Transport through an Aerolysin Pore

(2011) Manuela Pastoriza-Gallego et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

New insights into the biological effects of anthrax toxins: linking cellular to organismal responses

(2011) Annabel Guichard et al.   MICROBES AND INFECTION

Anthrax and the inflammasome

(2011) Mahtab Moayeri et al.   MICROBES AND INFECTION

The unfolding story of anthrax toxin translocation

(2011) Katie L. Thoren et al.   MOLECULAR MICROBIOLOGY

A Staphylococcus aureus pore-forming toxin subverts the activity of ADAM10 to cause lethal infection in mice

(2011) Ichiro Inoshima et al.   NATURE MEDICINE

Efficient Targeting of Head and Neck Squamous Cell Carcinoma by Systemic Administration of a Dual uPA and MMP-Activated Engineered Anthrax Toxin

(2011) Jeffrey M. Schafer et al.   PLoS One

Cross-Reactivity of Anthrax and C2 Toxin: Protective Antigen Promotes the Uptake of Botulinum C2I Toxin into Human Endothelial Cells

(2011) Angelika Kronhardt et al.   PLoS One

Tailored ß-Cyclodextrin Blocks the Translocation Pores of Binary Exotoxins from C. Botulinum and C. Perfringens and Protects Cells from Intoxication

(2011) Ekaterina M. Nestorovich et al.   PLoS One

Crystal structure of the Vibrio cholerae cytolysin heptamer reveals common features among disparate pore-forming toxins

(2011) S. De et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anthrax toxin protective antigen-Insights into molecular switching from prepore to pore

(2011) James G. Bann   PROTEIN SCIENCE

Antibody drug conjugates — Trojan horses in the war on cancer

(2011) U. Iyer et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

A Receptor-based Switch that Regulates Anthrax Toxin Pore Formation

(2011) Rosemarie M. Pilpa et al.   PLoS Pathogens

The Effects of Anthrax Lethal Toxin on Host Barrier Function

(2011) Tao Xie et al.   Toxins

Real-Time Monitoring of DNA Polymerase Function and Stepwise Single-Nucleotide DNA Strand Translocation through a Protein Nanopore

(2010) John Chu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The C2-streptavidin delivery system promotes the uptake of biotinylated molecules in macrophages and T-leukemia cells

(2010) Jörg Fahrer et al.   BIOLOGICAL CHEMISTRY

Polymer Partitioning and Ion Selectivity Suggest Asymmetrical Shape for the Membrane Pore Formed by Epsilon Toxin

(2010) Ekaterina M. Nestorovich et al.   BIOPHYSICAL JOURNAL

Blockage of Anthrax PA63 Pore by a Multicharged High-Affinity Toxin Inhibitor

(2010) Ekaterina M. Nestorovich et al.   BIOPHYSICAL JOURNAL

Potent inhibition of tumor angiogenesis by the matrix metalloproteinase-activated anthrax lethal toxin: Implications for broad anti-tumor efficacy

(2010) Randall W. Alfano et al.   CELL CYCLE

Role of CypA and Hsp90 in membrane translocation mediated by anthrax protective antigen

(2010) Lydia Dmochewitz et al.   CELLULAR MICROBIOLOGY

Symmetry Complementarity-Guided Design of Anthrax Toxin Inhibitors Based on β-Cyclodextrin: Synthesis and Relative Activities of Face-Selective Functionalized Polycationic Clusters

(2010) Alejandro Díaz-Moscoso et al.   ChemMedChem

Applications of biological pores in nanomedicine, sensing, and nanoelectronics

(2010) Sheereen Majd et al.   CURRENT OPINION IN BIOTECHNOLOGY

Ion Channel Biosensors—Part II: Dynamic Modeling, Analysis, and Statistical Signal Processing

(2010) Vikram Krishnamurthy et al.   IEEE TRANSACTIONS ON NANOTECHNOLOGY

Ion-Channel Biosensors—Part I: Construction, Operation, and Clinical Studies

(2010) Vikram Krishnamurthy et al.   IEEE TRANSACTIONS ON NANOTECHNOLOGY

Polymer translocation through α-hemolysin pore with tunable polymer-pore electrostatic interaction

(2010) Chiu Tai Andrew Wong et al.   JOURNAL OF CHEMICAL PHYSICS

Uni-molecular detection and quantification of selected β-lactam antibiotics with a hybrid α-hemolysin protein pore

(2010) Alina Asandei et al.   JOURNAL OF MOLECULAR RECOGNITION

Ion Selectivity of α-Hemolysin with β-Cyclodextrin Adapter. II. Multi-Ion Effects Studied with Grand Canonical Monte Carlo/Brownian Dynamics Simulations

(2010) Bernhard Egwolf et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Impact of Distant Charge Reversals within a Robust β-Barrel Protein Pore

(2010) Mohammad M. Mohammad et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Permeation through nanochannels: revealing fast kinetics

(2010) Kozhinjampara R Mahendran et al.   JOURNAL OF PHYSICS-CONDENSED MATTER

Facilitated translocation of polypeptides through a single nanopore

(2010) Robert Bikwemu et al.   JOURNAL OF PHYSICS-CONDENSED MATTER

Nanoscale Ionic Diodes with Tunable and Switchable Rectifying Behavior

(2010) Michael X. Macrae et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Processive Replication of Single DNA Molecules in a Nanopore Catalyzed by phi29 DNA Polymerase

(2010) Kate R. Lieberman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Inhibition of Tumor Angiogenesis by the Matrix Metalloproteinase-Activated Anthrax Lethal Toxin in an Orthotopic Model of Anaplastic Thyroid Carcinoma

(2010) R. W. Alfano et al.   MOLECULAR CANCER THERAPEUTICS

Exploring the role of host cell chaperones/PPIases during cellular up-take of bacterial ADP-ribosylating toxins as basis for novel pharmacological strategies to protect mammalian cells against these virulence factors

(2010) Holger Barth   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Internalization of biotinylated compounds into cancer cells is promoted by a molecular Trojan horse based upon core streptavidin and clostridial C2 toxin

(2010) Jörg Fahrer et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Anthrax toxin-neutralizing antibody reconfigures the protective antigen heptamer into a supercomplex

(2010) M. Radjainia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular bases of cyclodextrin adapter interactions with engineered protein nanopores

(2010) A. Banerjee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of a disintegrin and metalloprotease 10 in Staphylococcus aureus  -hemolysin-mediated cellular injury

(2010) G. A. Wilke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeted Toxins in Brain Tumor Therapy

(2010) Yan Michael Li et al.   Toxins

Toxin-Based Therapeutic Approaches

(2010) Assaf Shapira et al.   Toxins

Discrimination of Single Base Substitutions in a DNA Strand Immobilized in a Biological Nanopore

(2009) Robert F. Purnell et al.   ACS Nano

A Semi-Synthetic Ion Channel Platform for Detection of Phosphatase and Protease Activity

(2009) Michael X. Macrae et al.   ACS Nano

Prevention and Treatment of Staphylococcus aureus Pneumonia with a  -Cyclodextrin Derivative

(2009) B. E. Ragle et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Identification of the channel-forming domain of Clostridium perfringens Epsilon-toxin (ETX)

(2009) Oliver Knapp et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Transmembrane cholesterol migration in planar lipid membranes measured with Vibrio cholerae cytolysin as molecular tool

(2009) Oleg V. Krasilnikov et al.   BIOCHIMIE

Genetically Engineered Clostridial C2 Toxin as a Novel Delivery System for Living Mammalian Cells

(2009) Jörg Fahrer et al.   BIOCONJUGATE CHEMISTRY

Interaction of Heparins and Dextran Sulfates with a Mesoscopic Protein Nanopore

(2009) Luciana R. Teixeira et al.   BIOPHYSICAL JOURNAL

Humanized immunotoxins: A new generation of immunotoxins for targeted cancer therapy

(2009) Mrudula Mathew et al.   CANCER SCIENCE

Cyclophilin A facilitates translocation of theClostridium botulinumC2 toxin across membranes of acidified endosomes into the cytosol of mammalian cells

(2009) Eva Kaiser et al.   CELLULAR MICROBIOLOGY

Nanopore analytics: sensing of single molecules

(2009) Stefan Howorka et al.   CHEMICAL SOCIETY REVIEWS

The Dynamic Side of the Hofmeister Effect: A Single-Molecule Nanopore Study of Specific Complex Formation

(2009) Philip A. Gurnev et al.   CHEMPHYSCHEM

Pathophysiology of anthrax

(2009) Arthur et al.   Frontiers in Bioscience-Landmark

Investigation of New Dominant-Negative Inhibitors of Anthrax Protective Antigen Mutants for Use in Therapy and Vaccination

(2009) S. Cao et al.   INFECTION AND IMMUNITY

Evidence for a Proton–Protein Symport Mechanism in the Anthrax Toxin Channel

(2009) Daniel Basilio et al.   JOURNAL OF GENERAL PHYSIOLOGY

The Protective Antigen Component of Anthrax Toxin Forms Functional Octameric Complexes

(2009) Alexander F. Kintzer et al.   JOURNAL OF MOLECULAR BIOLOGY

Study of Peptide Transport through Engineered Protein Channels

(2009) Qitao Zhao et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Ion Selectivity of α-Hemolysin with a β-Cyclodextrin Adapter. I. Single Ion Potential of Mean Force and Diffusion Coefficient

(2009) Yun Luo et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Gramicidin Pores Report the Activity of Membrane-Active Enzymes

(2009) Sheereen Majd et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Lipid bilayer regulation of membrane protein function: gramicidin channels as molecular force probes

(2009) J. A. Lundbaek et al.   Journal of the Royal Society Interface

Receptors of anthrax toxin and cell entry

(2009) Gisou van der Goot et al.   MOLECULAR ASPECTS OF MEDICINE

Membrane translocation by anthrax toxin

(2009) R. John Collier   MOLECULAR ASPECTS OF MEDICINE

The surface of Bacillus anthracis

(2009) Agnès Fouet   MOLECULAR ASPECTS OF MEDICINE

Cellular and systemic effects of anthrax lethal toxin and edema toxin

(2009) Mahtab Moayeri et al.   MOLECULAR ASPECTS OF MEDICINE

Anthrax Toxin Uptake by Primary Immune Cells as Determined with a Lethal Factor-β-Lactamase Fusion Protein

(2009) Haijing Hu et al.   PLoS One

Lethal factor unfolding is the most force-dependent step of anthrax toxin translocation

(2009) K. L. Thoren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-nucleotide discrimination in immobilized DNA oligonucleotides with a biological nanopore

(2009) D. Stoddart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Listeriolysin O as cytotoxic component of an immunotoxin

(2009) Sabine Bergelt et al.   PROTEIN SCIENCE

Interrogating single proteins through nanopores: challenges and opportunities

(2009) Liviu Movileanu   TRENDS IN BIOTECHNOLOGY

Medical countermeasures to protect humans from anthrax bioterrorism

(2009) Dimitrios G. Bouzianas   TRENDS IN MICROBIOLOGY

In Vivo Efficacy of  -Cyclodextrin Derivatives against Anthrax Lethal Toxin

(2008) M. Moayeri et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Amino Acid Residues Involved in Membrane Insertion and Pore Formation ofClostridium botulinumC2 Toxin†

(2008) Alexander E. Lang et al.   BIOCHEMISTRY

Sizing the Bacillus anthracis PA63 Channel with Nonelectrolyte Poly(Ethylene Glycols)

(2008) Brian J. Nablo et al.   BIOPHYSICAL JOURNAL

Nonexponential Kinetics of DNA Escape from α-Hemolysin Nanopores

(2008) Matthew Wiggin et al.   BIOPHYSICAL JOURNAL

Binary Actin-ADP-Ribosylating Toxins and their Use as Molecular Trojan Horses for Drug Delivery into Eukaryotic Cells

(2008) Holger Barth et al.   CURRENT MEDICINAL CHEMISTRY

Excursion of a single polypeptide into a protein pore: simple physics, but complicated biology

(2008) Mohammad M. Mohammad et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

A Single-Molecule Nanopore Device Detects DNA Polymerase Activity with Single-Nucleotide Resolution

(2008) Scott L. Cockroft et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Single-Molecule Detection of Nitrogen Mustards by Covalent Reaction within a Protein Nanopore

(2008) Hai-Chen Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The potential and challenges of nanopore sequencing

(2008) Daniel Branton et al.   NATURE BIOTECHNOLOGY

GroEL as a molecular scaffold for structural analysis of the anthrax toxin pore

(2008) Hiroo Katayama et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Proton-coupled protein transport through the anthrax toxin channel

(2008) A. Finkelstein   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Role of N-Terminal Amino Acids in the Potency of Anthrax Lethal Factor

(2008) Pradeep K. Gupta et al.   PLoS One

Single-molecule DNA detection with an engineered MspA protein nanopore

(2008) T. Z. Butler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid detection of influenza A virus in clinical samples using an ion channel switch biosensor

(2007) S.Y. Oh et al.   BIOSENSORS & BIOELECTRONICS